Skip to main content

All Questions

Tagged with
Filter by
Sorted by
Tagged with
7 votes
2 answers
66 views

Meaning of "stripped" in "stripped antibody-depleted sera"

From a research paper: FOLR1 autoantibody detection The assay for identification of the presence and relative quantification of FOLR1 autoantibodies in serum samples was performed as previously ...
CopperKettle's user avatar
  • 1,309
1 vote
2 answers
6k views

What is a "pan-specific" antibody?

I am new to biology. I searched a lot to find an article that explains what "pan-specific" antibody is but I could not find anything substantial that would help me understand what it is. An example ...
Tooba's user avatar
  • 13
1 vote
2 answers
206 views

How do I name a binding antibody? “Binding antibody to”, “binding antibody against”, or “anti-[antigen] binding antibody”?

I'm translating a text that describes how an immunogenicity of a drug is measured by assaying the levels of binding antibodies to the drug. Or is it "against the drug"? I'm wondering how to name these ...
CopperKettle's user avatar
  • 1,309
1 vote
1 answer
91 views

Difference between ‘tagging’ and ‘conjugating’ a fluorochrome to an antibody?

The Wikipedia entry on fluorescence repeatedly states that “a fluorochrome must be tagged or conjugated to the antibody”. How is tagged or conjugated different? Is this a mistake or are these indeed ...
C.Colden's user avatar
  • 158
0 votes
1 answer
61 views

Meaning of "Antibody is 50% w/w pure of interfering proteins"

From Google Patents, "Preparing antibodies from cho cell cultures for conjugation": An isolated antibody or ADC is typically at least 50% w/w pure of interfering proteins and other contaminants ...
CopperKettle's user avatar
  • 1,309
5 votes
1 answer
11k views

What is immunopanning (vs. immunoprecipitation and FACS)?

I had never heard the term before today. From what I can tell, it's using antibodies to purify a cell population of interest. I would appreciate more details, especially in how it differs from "...
blep's user avatar
  • 2,824