Questions tagged [antibody]

A protein produced by the B-cells of the immune system which binds to a particular antigen, a foreign substance to the body.

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3
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2answers
9k views

Can more than one antibody bind the same antigen

I'd like to clear something up about antibodies that I'm not sure I've understood in the articles I've read. Looking at concepts such as "affinity maturation", "monovalent antigens" and "polyvalent ...
7
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1answer
763 views

How plasma cells switches secreting different Ig classes?

In Type 1 hypersensitivity how do B lymphocytes switch Ig classes, from synthesizing IgG to IgE? What is the mechanism? I studied multiple pathology books, it says the same as for IgG secreting ...
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1answer
202 views

IgA-s in an immune system vaccined intramuscularly against Hepatisis A

As IgA are immunoglobulins associated with secretion and mucosis membranes, I am interested whether after intramuscular vaccination with Hepatitis A vaccine IgA antibodies will be produced by the ...
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2answers
131 views

How can mutation of viruses lead to loss of fit to antibodies without loss of fit to antigen of cells they infect?

Viruses are known to mutate, thereby escaping immune cells and evading vaccination. Given that there is one and the same specificity of the key to both the receptor on the infected cell causing the ...
10
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2answers
617 views

How are antibodies designed?

Antibodies have the ability of recognising highly specific peptide sequences and bind it at their antigen-binding site. This ability is harnessed as a tool in research to purify target structures in ...
4
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1answer
1k views

Why is the administration of exogenous Anti-D not harmful to the foetus?

Haemolytic disease of the newborn can result from Rhesus incompatibility in utero. In this disease an Rh- mother becomes exposed to the antigens of an Rh+ foetus by fetomaternal haemorrhage causing ...
3
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1answer
125 views

How to inhibit formation of specific antibodies (to antisera)?

Is there a way to inhibit an antibody response to a specific antigen using immunosupression? I am interested in reducing the anti-antibody formation to animal antibodies such as murine antibodies in ...
0
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1answer
42 views

How are antibodies specific for a disease detected in the blood if everybody produces a different antibody for the same antigen?

To break the title down into parts: There exist serology tests that detect the amount of an antibody (Ab) against a specific pathogen/antigen. Every human produces their own Ab for a specific ...
11
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2answers
8k views

Is there a maximum amount of antibodies your body can keep?

I am wondering if you were theoretically able to get vaccinations or antibodies for any and every diseases and/or illness, would there be a limit to how many you can get and keep in your body at one ...