Questions tagged [biomedical-engineering]

The application of engineering principles and design concepts to medicine and biology for healthcare purposes (e.g. diagnostic or therapeutic). This field seeks to close the gap between engineering and medicine: It combines the design and problem solving skills of engineering with medical and biological sciences to advance health care treatment, including diagnosis, monitoring, and therapy.

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What is a good expression vector for Salmonella enterica subsp. enterica serovar typhimurium

I am interested in expressing custom proteins in a Salmonella strain, however I am facing difficulties in finding the appropriate expression vector for it. It seems that most of the resources provide ...
John Appleseed's user avatar
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Why is there a negative sign before voltage in the gate variable functions of the Hodgkin-Huxley model?

In Hodgkin and Huxley's articles (1952, J. Physiol.; 1990, Bulletin of Mathematical Biology), the gate variables are formulated as In particular, as $V$ increases, $\alpha_n$ decreases and $\beta_n$ ...
Jasmine's user avatar
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Recent developments in the diagnosis of Parkinson's Disease

I was reading a research paper titled - "Discovery of Volatile Biomarkers of Parkinson’s Disease from Sebum" by Drupad K. Trivedi. I am Providing a short summary of it. Discovery of ...
Ankush Yadav's user avatar
1 vote
1 answer
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Is the Malaria vaccine the first vaccine against a Eukaryote?

RTS,S or Mosquirix was recently released to the public, offering the first Malaria vaccine. This struck me as particularly important because I don't know of any other vaccine that protects against ...
Shmuel Newmark's user avatar
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Have the potential therapeutic applications of cell fusion between cancer cells and neural cells been investigated?

Studies have appeared on the possible role that cell fusion plays in the formation of certain cancers. For instance, Sitar et al. (2019) have looked into the process of cell fusion in the formation of ...
Max Muller's user avatar
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1 answer
125 views

The Perfect Predator? [closed]

I’m not a biology major or even studying it in any way so I apologize if this makes no sense. I’m curious, if say the Jurassic Park team came up to you and asked you to genetically engineer the ...
Ghull's user avatar
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4 votes
1 answer
294 views

What happens with the nitrogen in blood in membrane oxygenators?

The air we breathe consists of about 80% nitrogen and 20% oxygen. The oxygen gets diffused into the blood and CO2 out of it, the nitrogen does mostly nothing, as there isn't a partial pressure of ...
user9000's user avatar
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Techniques of molecular medicine/biology for aesthetic medicine?

Are there scientifically valid methods (possibly in the developmental stage) that can be used for aesthetic medicine. Usually surgical of physical therapies are used for aesthetic medicine, but ...
TomR's user avatar
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Will DNA nanostructures be useful for medical applications?

There is a lot of work being done on developing small nanomechanical structures and even small nanomechanical actuators built with DNA. I have heard researchers motivate this research with claims ...
wanderingmathematician's user avatar
2 votes
2 answers
266 views

Are there any place in human body that safe to implant things and have large amount of blood run through?

Suppose there was a fuel cell in the size of AAA battery that could convert human blood sugar into electricity. Assume it safe and efficient without causing allergic reaction. But to avoid the risk of ...
Thaina's user avatar
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Young family members to learn genetics - Amino Labs? [closed]

I'm an engineer but want to learn about biology with a niece and nephew who are early teens. I saw Amino Labs (https://amino.bio/) and thought because I work a lot with my hands, doing hands on ...
user97113's user avatar
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How is the Guide RNA created for Crispr?

It seems that to modify DNA a guide RNA and Cripr are introduced. But I'm unable to understand how the Guide RNA is made or created. Is it a simple method which can be done with simple lab equipment ...
Wally's user avatar
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Single wire pacemakers

There are single wire pacemakers used for regulating heart beat. The wire will conduct pulse to the heart. How can one wire be enough? Where is the reference wire for the stimulation of heart?
lkjhg's user avatar
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4 votes
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Are there medical imaging devices to look inside artery? [duplicate]

Are there medical imaging devices to look inside artery? If yes, what is there sensitivity i.e. smallest object they can detect?
rkb's user avatar
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In Vitro Meat Initial Production

I've gotten interested in the science behind in vitro meat, and I was wondering what would be necessary to create it. Would you initially need a primary culture, or an immortalized cell line? And how ...
Sarah Rune's user avatar
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Absorbable stents

Stents are tubular scaffoldings, which are used to expand blocked arteries. Absorbable stents dissolve after few years. Shouldn't the blood vessel become narrow again once the stent has dissolved?
nth's user avatar
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Mosquito vs Human: Swapping the roles

Is there a known mosquito-specific lethal (for some relevant species of mosquitos) virus that you could safely (for the humans) put into the blood of living humans? Is it technically possible to ...
user66081's user avatar
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1 answer
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What is PDMS used for in microfluid models?

When creating a microfluidic model using polydimethylsiloxane (PDMS), is PDMS used only as a stamp to lay proteins in coverslips or can cells be cultured in the channels or patterns created in PDMS?
user27407's user avatar
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2 answers
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What is the difficulty with cloning and genetic engineering in humans?

I asked this question many years ago and was told by my molecular biology professor that humans were (simply) more complicated than goats. So, I didn't get a straight answer, but supposing he told ...
Ben Welborn's user avatar
4 votes
1 answer
193 views

How specific are CRISPR-cas9 cuts?

CRISPR-cas9 uses a string of RNA that matches with DNA and makes a double stranded cut at that point. If the RNA is just a few letters in length, the enzyme would cut DNA in many places. It would be ...
user1889150's user avatar
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1 answer
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iPSC in drug discovery

Pluripotent stem cells are very popular and lots of research has been conducted to use these cells as a tool for drug discovery. My question is how many years would it theoretically safe is we could ...
user53411's user avatar
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1 answer
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How does a test like the Natera Panorama distinguish the child's genome from the mother?

Blood tests on an expectant mother, like the Natera Panorama, are now being used regularly to screen fetuses for chromosome abnormalities. At my wife's recent prenatal visit, she wasn't really even ...
Mark Bailey's user avatar
11 votes
1 answer
40k views

How do disulphide bonds in hair cause curling?

I understand that there are several characteristics of curly hair which differ from straight hair (such as an asymmetrical distribution of disulphide bonds in curly hair), but really am struggling to ...
User2341's user avatar
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1 vote
0 answers
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Large set of semen microscope images needed

As a course project I have to write an algorithm whose purpose is to analyze a sperm sample (total number, motility etc). In order to do that though, I need to have a sufficient number of images to ...
bergercookie's user avatar
2 votes
1 answer
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Are there antibiotics for all bacteria somewhere in the earth? [closed]

When I read about Penicillin, I found that it came from a green mold to protect itself. If all bacteria and/or molds in competition to survive, can we believe that there is an antibiotic for each ...
Trailblazer's user avatar
2 votes
2 answers
513 views

What makes diffculty to make a human bio-tooth compare to a mouse's? [closed]

Some time ago I read a news article that said a bio-engineered tooth based on a mouse's would be available around 2015. There was some research about it at King's College in the UK, and many other ...
Trailblazer's user avatar
15 votes
2 answers
2k views

How to make a fake auditory signal?

My question is about making fake auditory signals. The ear collects sounds from the environment, which are transformed into a neural signal by the hair cells in the inner ear. This signal is sent ...
Nimda's user avatar
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5 votes
1 answer
221 views

How can electric fields inhibit tumor growth?

In MIT's Technology review it is explained that electric fields can cause dividing cancer cells to explode, while these fields have no significant impact on non-dividing tissues. The original research ...
Kevin Kostlan's user avatar
5 votes
1 answer
365 views

Are there any known health benefits / risks from milliampere current (0.1-2 mA) on forehead?

This is about devices like that sold by foc.us that allows user to apply a small current on a specific part of the forehead. For the sake of this question I use the foc.us "gamer" model as example. ...
x457812's user avatar
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