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Questions tagged [cell-biology]

The study of cells, their physiological properties, structure, environmental interaction, division, life cycle, and death, as well as the organelles they contain. Also known as cytology.

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1answer
165 views

Does a theory exist for the formation of thylakoid structure?

I'm interested in how the structure of the thylakoid forms into its characteristic highly rugose stacks of grana. What causes the thylakoid to invaginate and self-associate, albeit with what appear to ...
7
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4answers
15k views

RNA or ribosome, which one moves during translation?

During translation ribosomes decode the genetic information present in the mRNA and protein synthesis takes place. During this process which of those two does move, the ribosome or the mRNA?
7
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1answer
274 views

When collecting cell lysates for a Western blot, how do I induce di-sulfide bonds?

I would like to conduct a simple dimerization experiment for some protein I'm collecting from a cultured cells. My thought is, that if I'm running a non-reducing, denaturing PAGE gel, then removing ...
6
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2answers
124 views

Synthetic biology using existing cells

I was watching the video at this link: http://www.bbc.co.uk/news/science-environment-17436365 The speaker says that a cell is taken and its original DNA content is stripped out and replaced with ...
10
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1answer
3k views

What is a inhibitory tone when talking about neurons?

In this SE answer: Could an "overactive" brain increase the chances of Alzheimer's Disease? user @nico used the word inhibitory tone What does that ...
9
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3answers
49k views

What is the difference between “dikaryotic” and “heterokaryotic” states in the sexual lifecyles of fungi?

Many fungi undergo a reproductive phase in which more than one genetically distinct nuclei (from 2 separate mating types) is present within the same cytoplasm. In the Ascomycota and Basidiomycota, ...
38
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1answer
840 views

How does a cell sense its size?

Cells come in all sorts of sizes. How do they regulate their cell size to the point where similar cell types have a fairly mono-disperse size distribution? Reasked from http://www.quora.com/How-Does-...
10
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1answer
2k views

Do larger multicellular organisms have an increased risk of mutation and thus cancer?

So I was thinking that if each cell has P(X) of becoming cancerous, then the chance of cancer is 1-((1-P(X))^n) where n is the number of cells in the organism. Since larger organisms have more cells ...
4
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1answer
2k views

What's the distinction between a tetrad and a synaptonemal complex in meiosis?

What's the distinction between a tetrad and a synaptonemal complex in meiosis? Are they synonyms? I ask because the concepts seem very closely related, but it seems like there may be a subtle ...
8
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1answer
116 views

Pancretic Acinar Cell - ATP, calcium concentration data

I need to find a decent source of data for concentration of ATP and calcium in the pancreatic acinar cell. So far all I can find is ATP or calcium 'levels' based on fluorescence , which are not ...
24
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3answers
489 views

How crowded is the bacterial cell?

I was wondering what is the protein concentration in an E. coli cell. When studying enzyme kinetics and activity in vitro, I would argue that the substrate and enzyme concentrations resemble those in ...
10
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1answer
997 views

How is the number of mitochondria in a cell regulated?

How does the cell regulate the number of mitochondria in a cell? What happens when there are too many or too few?
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1answer
2k views

X chromosome “weight”?

According to Wikipedia, the X chromosome has approximately 153 million base pairs, while the Y chromosome has only 60 million base pairs. Thus, the difference is roughly 93 million base pairs. My ...
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2answers
1k views

What is the main general difference between Mitosis and Meiosis?

I found such a clause: The general principle is that mitosis creates somatic cells and meiosis creates germ cells. However, I cannot agree. Each gametogonium needs to go through mitosis before ...
14
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1answer
3k views

Does electricity cause damage on a cellular level?

As I understand it the mechanism of death when a mammal is electrocuted is that the current disrupts the SAN/AVN in the heart causing it to fibrilate or arrest. That's on a macro scale, however. ...
6
votes
1answer
633 views

What's a good reference for choosing histological staining chemicals?

It's often difficult to find the appropriate or best stain to use when I want to examine a new type of tissue. I think that's partly because many histological techniques were developed a long time ago,...
7
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1answer
5k views

How does water buffer a sudden drop in temperature?

A property of water is that it is slow to heat and cool. According to my biology book, some energy from an increase in temperature would spent breaking hydrogen bonds, so that temperature does not ...
31
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1answer
7k views

How long will a vegetable live for after being harvested?

I understand this might depend on the types of vegetables, but is there an average or studied specifics? Does it die immediately? Is there a way to precisely diagnose death in plants? If so, what are ...
6
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1answer
113 views

How are chromatids correctly segregated during mitosis?

In my book this is described as happening by kinetochores depolymerising from their attached microtubule spindle, then being dragged towards the spindle's centrosome by a dynein protein. I can ...
13
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1answer
721 views

Did researchers evolve multicellular yeast or did they just turn on multicellularity?

In this new paper "Experimental evolution of multicellularity" found via Ars Technica the researchers describe having developed multicellularity and apoptosis within 60 days from a unicellular yeast ...
8
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3answers
2k views

What triggers meiosis in gonadal cells?

What specific biochemical processes are involved in inducing meiosis rather than mitosis? Why are gonadal cells the only cells in the human body which do undergo meiosis?
6
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1answer
2k views

How does the Golgi Apparatus perform its function?

The Golgi Apparatus is an organelle with a great number of functions, I am particularly intrigued in the role it plays in packaging macromolecules and sending them to their target organelle or to ...
8
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2answers
335 views

Is “exhaustion” of the Hodgkin-Huxley membrane at constant stimulation a real phenomenon?

I was playing around with a simulation of the Hodgkin-Huxley model using their original parameters for the squid giant axon. By applying a constant stimulation current to the model in resting state, ...
7
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1answer
748 views

To understand why satellite cells are genetically inactive in Barr body

DAPI is used as a stain for DNA heterochromatic and euchromatic regions. The Barr body is heterochromatic. In the slide of a normal human female cheek's somatic cells, there is apparently no other ...
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6answers
4k views

Online Molecular and Cellular Biology Video Lectures?

I am looking for video lectures to go through to guide my reading in intro molecular and cellular biology. I've had intro bio and I study evolutionary theory, but my molecule- and cell-level knowledge ...
7
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1answer
217 views

How Do Large Ocean Viruses Form Their Own Organelles?

Several large viruses (Arslan 2011) form their own organelles within the amoebae they invade. How do these organelles form? Reference: Arslan, D., Legendre, M., Seltzer, V., Abergel, C., Claverie, ...
9
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1answer
173 views

What specific membrane adaptations do cells have for saline-rich environs?

Are the cells of marine animals and flora equipped with special ion exchange pumps to mitigate the effects of a saline-rich environment? Or have the cell's membranes adapted through structural ...
22
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1answer
781 views

Are lymphocyte sizes clustered in two groups?

Tortora writes in Principles of Anatomy and Physiology: Lymphocytes may be as small as 6–9 μm in diameter or as large as 10–14 μm in diameter. Those ranges are quite close to each others. Should ...