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Questions tagged [circadian-rhythms]

Any biological process which displays an endogenous, entrainable oscillation of time.

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Circadian clocks in enzymes

I'm aware of the existence of circadian clocks, but I don't understand exactly how circadian clocks regulate other circadian mechanisms. For example, if an enzyme is found to have a circadian rythm, ...
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Delay of sleeping on cortisol cycle

I was told that cortisol has to be measured at 9am or 4pm, because those where its peak level. But I wonder if changes on sleep patters affect the cortisol cycle. I mean, if I usually go to sleep ...
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What is the purpose of Prostaglandin F2-alpha and the Prostaglandin F receptor in the melatonin cell signaling pathway?

I've been doing a lot of research recently on the melatonin cell signaling pathway for an extra credit project at school. I've included an image in this post, which is a diagram of the MT1 pathway. It ...
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127 views

How would our circadian rhythm change over time if we had no sunlight whatsoever?

Of course, over the span of a couple days, our circadian rhythms would lengthen a few hours. But what would happen to the circadian rhythms of humans overall if we had no daylight ever? Say we can ...
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Does iris color effect the amount of light that reaches photosensitive ganglion cells?

Does eye color (of iris) have any effect on the amount of light reaching retina cells and hence effect melatonin production?
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434 views

Is there a difference between sleeping late and waking up late vs sleeping early and waking up early?

For example, if I sleep at 1 AM and wake up at 10 AM, will it negatively affect my health opposed to sleeping at 10 PM and waking up at 7 AM?
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How does the body count time in the short term?

So I've done some research and found out about the different circadian cycles that use chemical clocks to help us keep time in the long term (hours, days, etc.). This doesn't seem to explain how we ...
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224 views

What is blue light?

What is the "blue light" often discussed in relation to human melatonin production, sleep/wake cycles, etc.? A Google search seems to define it as light of a particular wavelength, suggesting that it ...
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Why are fearful stimuli more powerful at night?

For example, horror movies appear to be scarier when viewed at night than during broad day light. Does light have any role in this phenomenon? Are there changes in hormones at night versus during ...
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Variation of length of circadian rhythm in humans in absense of time reference

Are there any studies which show the range of the length of circadian rhythms for people that are removed from actual time, (Eg no sunset/ sunrise, no clocks or other reference of time)? For example, ...
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Does apoptosis occur more at a particular time of day?

I am interested to know if apoptosis (programmed cell death) occurs more frequently during daytime or nighttime hours, e.g. if apoptosis is associated with a circadian rhythm. A simple search turned ...
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468 views

How can space-time affect ageing? [closed]

I recently watched the movie -"interstellar" and I came through the question that how can ageing be affected by space-time? Wherever I look, I get it as a fact that it's kind of ageing slows down in ...
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Photoperiodism: Short-Day Plants

My Campbell's Biology textbook discusses photoperiodism of plants and introduces us to short-day and long-day plants. What I don't understand is why short day plants will not flower if they are ...
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What is the connection between sleep requirement and age?

By this question: Is the human biological clock genetically programmed or learnt? we discussed that the sleep requirement depends on the age of the individual. - Figure 1. - Sleep requirements by age ...
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Is the human biological clock genetically programmed or learnt?

Argument favouring learning: A newborn sleeps for 20-22 hours. But overtime (s)he learns to focus sleeping time to night time, according to his or her needs and family needs. Some sleep from 1 am to 7 ...
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How did the introduction of artificial light changed the life cycle of a plant?

Plants in urbanized areas are constantly exposed to artificial light after sunset. In their natural habitat there is a more distinct day and night cycle. Since light is an important factor in a plant ...
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Circadian Clock During a Flight

I am interested in knowing how our Circadian Clock responds (and if there are resultant changes) when we travel across Time Zones? UPDATE 24th April I am reopening this question as the statement in ...
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Why aren't circadian rhythms exactly 24 hours long?

Most organisms exhibit circadian rhythms that have a periodicity of about, but not exactly 24 hours. Why is this? And to what extent can variation in periodicity in circadian rhythms among the ...
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How do humans perceive time?

We can see length, and other physical quantities. We can perceive through our other senses like (temperature through thermoreceptors, weight through pressure receptors etc.). But how do we "sense" ...
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How do PER/CRY complexes accumulate in the cytoplasm?

The Period/Cryptochrome (PER/CRY) complex is a heterodimer that transcriptionally regulates circadian rhythm. When it is phosphorylated, it is transported to the nucleus and it inhibits a ...
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Would constant light or fading light be registered as more wakefulness promoting by the Supra Chiasmatic Nucleus?

During the fall and winter season, a number of people are experiencing Seasonal Affective Disorder. One of the way it has traditionally been treated is with a dedicated lightbox - a very high ...
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3answers
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Why do we weigh less in the morning?

At first I thought it may be related to physics. You know, in one half of the day, the gravity changes, and the scale shows a different weight than the other. Then at night, gravity intensifies, and ...
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308 views

High frequency human genetic oscillators?

The most well studied genetic oscillators in human genomes are involved in regulating the circadian clock (which operates on an approximately 24-hour cycle) and cell cycle activity (with single cycles ...
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Is there a correlation between brain size and amount of sleep? [closed]

As far as we know, sleep seems to be the part of the daily cycle when executive functions are resting and memories are fortifying. Many, but not all, of the functions that become dysfunctional upon ...
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341 views

How would a different solar day affect evolution?

Has anyone theorized how evolution would be affected by a different length of solar day, what were the conclusions? The thought came from thinking about life on other planets/moons, but I'm initially ...
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Circadian rhythm in birds

Animals can use their circadian clocks to determine direction from the position of the sun. In a particular experiment conducted in Iceland, a bird, kept in a cage open to the sky, was trained to ...
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What is the cause of singularity in phase response curve of human sleep and bright light?

I have no background in science as I am a computer programmer, but I am trying to get information on phase response curves, human sleep and exposure to bright light as I am trying to get to grips with ...
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1answer
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Does sleep duration vary for animals based on time of the year?

I'm interested in the sleep patterns of wild animals, that still use sun for controlling their biological clock. Animals entrain their biological clock to the day/night cycle using light as the ...
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1answer
254 views

Do lunar rhythms have impact on human biology, if so, how?

I'm approaching this question from the circadian rhythm perspective. A circadian rhythm is a 24 hour cycle. While doing research on deep sea circadian rhythms, I found this abstract which seemed to ...
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Do marine deep sea life forms exhibit circadian rhythms? If so, what entrains them?

I've been reading a lot about circadian rhythms, when suddenly this question popped into my head: do circadian rhythms exist for deep sea organisms (3000 ft / 1000 meters+)? For land mammals, the ...
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1answer
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What non invasive methods of estimating Body Time are there?

I found this article on estimating body time using molecular timetable of 168 genes. researchers looked at gene expressions and plotted them to 24 hour cosines curve with some pretty spectacular ...
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1answer
625 views

What is the mechanism of regulation of PER /CRY genes?

I've read multiple descriptions of biological/circadian clocks and they all mention PER, CRY and CLOCK genes. While I kinda get how they are connected, what interests me is how these actually regulate ...
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1answer
218 views

Is there a comprehensive list of human circadian-like processes, hormones or gene expressions?

I'm reading this article onblood sugar and circadian rhythms and the following question popped into my head: a lot of articles mention various diurnal or circadian rhythmicity of biological processes. ...
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What causes adenosine build up in the brain when awake?

Adenosine is an important hormone in sleep regulation. It is postulated that when a person is awake, there is a build up of adenosine in the brain, which inhibits the neurons in the brain, and ...
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1answer
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Is there an optimal illumination level for human habitats/workplaces?

I know of melanopsin, a photo pigment in mammal eye that helps regulate circadian rhythms. It responds most strongly to blue spectrum light. There have been experiments that demonstrated that ...
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137 views

Are (baseline) high blood levels of melatonin associated with either circadian rhythm or mood disorders?

(Exogenous) melatonin is administered at night for treatment of circadian rhythm disorders, but melatonin taken during the day is linked with depression. I would like to know if high blood levels of (...
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Is there an entry-level circadian model of serotonin, ghrelin, dopamine and the sense of well being?

I've long been interested in circadian rhythms and recently came across a variety of articles that appear to indicate that the following neurotransmitters, transferases and hormones are connected. ...
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242 views

Are serotonin levels in humans affected by light?

I'm reading this Wikipedia article on light therapy and noticed a peculiar statement: The production of the hormone melatonin, a sleep regulator, is inhibited by light and permitted by darkness ...
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1k views

Is there a normal human melatonin concentration to light level curve?

I'm looking for a graph or a curve that would show the typical concentration of melatonin in blood or saliva for humans over 24 hours. It would be good to know the photoperiod for the same human as ...
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What light intensity starts melatonin release in humans?

I'm interested in whether any studies have determined the intensity of light at eye level that starts melatonin release in humans. I know that: melatonin release is suppressed by blue light with ...
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1answer
137 views

Does artificial heat (shower/tea) affect diurnal rhythms in humans?

I've been reading that over the course of the day, human body temperature follows diurnal rhythm with the lowest body temperature observed some time close to the middle of the sleep episode, while the ...
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2answers
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Is there a circadian component to hunger?

I'm wondering what produces the feeling of hunger in humans. Checking Wikipedia revealed that leptin and ghrelin are two hormones involved. I've also read that the digestive system produces its own ...
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Can the sleep/wake cycle be influenced by non-visible spectrum electro-magnetic radiation?

I've been reading a few papers on Melanopsin and Suprachiasmatic Nucleus (SCN), and see that the sleep/wake transition is ...
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2answers
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Do men have significant hormonal cycles?

I know there's a similar question here. But that discussion dissolved into lunar cycle and a correlation with it. I want to find more towards the original question of is there a periodic hormone ...
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1answer
306 views

What biological systems are affected by Vitamin B6 (or B vitamins in general)?

B vitamins and particularly the B6 vitamin appears to the one of the main ingredients in energy drinks. There has been anecdotal evidence from people interested in dreaming that ingestion of vitamin ...
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632 views

How is human biological clock modelled in modern science?

Im an engineer by education and i program a lot, so the question sounds weird to people from other disciplines. Im trying to better understand the human biological clock. Yet i do not really know ...
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2answers
969 views

Is it possible to live without health problems sleeping one day and not the other?

Basically, I want to know if it would be humanely possible to sleep one day, skip the next, sleep, skip, sleep, skip, etc, with a 8 hour sleep time. If you need any extra information, let me know.
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582 views

What can the timing of human urination tell about the human's physical condition and circadian rhythms?

I've noticed a peculiar phenomenon. A subject drinks 400 ml of water, then observes time until the urge to urinate is felt. The time is 15 minutes. The subject releases water. 14 minutes later another ...
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1answer
363 views

Why is maintaining a circadian rhythm important?

What are the real consequences of never maintaining a circadian rhythm? How is circadian rhythm important for health and function? Where did it arise in evolution?
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What influences the timing of human bowel movements in the morning?

I'm trying to understand if the timing of human bowel movements in the morning is associated with the circadian rhythm, and can thus be used to make predictions about the circadian rhythm. What ...