We’re rewarding the question askers & reputations are being recalculated! Read more.

Questions tagged [dna]

Deoxyribonucleic acid (DNA) is the carrier of genetic information, including for all known living organisms. The only known exceptions are RNA viruses.

Filter by
Sorted by
Tagged with
-1
votes
1answer
37 views

From DNA data, is it easier to conclude that chimpanzees are our close relative, than it is to do a paternity testing?

Well, today I was contemplating on how to explain evolution, approaching with the dialectic method. When it came to why chimpanzees and us being so close in the tree of evolution isn't outright absurd,...
0
votes
0answers
48 views

DNA of Different Species and The Fossil Record of Their Common Ancestor

Let me please be clear about something. I believe in evolution. The evidence and data are compelling and conclusive which makes it a very well-established theory. I'm seeking a certain evidence (if ...
-1
votes
0answers
22 views

If humans have shorter telomeres than mice, why then do we have longer lifespans? [duplicate]

Since telomeres are associated with aging, and longer telomeres means more cell divisions the cell is capable of, then longer telomeres mean longer lifespans. But then mice have longer telomeres than ...
0
votes
5answers
110 views

What is the fundamental difference between human genome and other genomes that makes human a self-conscious living organism?

DNA is considered to be the blueprint from which any organism can be created. DNA carries the genetic information to construct a living body. DNA carries genes which represents the information that is ...
2
votes
1answer
61 views

Taq Polymerase's stability at high temperature

I was asked a question as to what is so special with Taq Polymerase that makes it quite stable at high temperatures though its functioning is the same as other DNA polymerases like that of mesophiles. ...
3
votes
1answer
67 views

Are there any ways to force DNA-origami to create a geometric shape from non-nucleotides (not from DNA)?

I mean, can we create with the help of DNA-origami figures that would not consist of DNA, but, for example, carbon? Is it even possible?
-1
votes
0answers
39 views

What are the forces involved in giving each and every one of the $DNA$ (out of kazillions) the helix shape?

I am not a biology student. So please bear with me if the question is nonsense. Almost all of the heavenly bodies are almost spherical. This can be easily explained using theory of gravity. But each ...
0
votes
0answers
51 views

How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share?

How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share? There are articles online that indicate that humans share xxx% of DNA with Chimpanzees, bananas, and other assorted ...
3
votes
1answer
73 views

Why do we need to amplify DNA sequences?

I am learning about biotechnology. I have no education in biology or chemistry and am simply interested in the subject of biotechnology. I am wondering why we need to have multiple copies of a piece ...
1
vote
2answers
50 views

How do mutations and protein synthesis link to cancer?

How do mutations and protein synthesis link to cancer? I know that a mutation in DNA can cause the triplet code on the mRNA to change so different amini acids are made and a different order means a ...
0
votes
2answers
105 views

Does it make sense to make my own DNA copy (kind of backup) while I am young?

As I understand, when I am getting older DNA becomes more and more damaged in my body. Does it make sense to make my own DNA copy (kind of backup) while I am young (38 years old or for my kids) in ...
0
votes
0answers
17 views

How much DNA can differ among different humans today?

According to this article, Australian aborigines carry unknown DNA Australian Aboriginal people carry the DNA of an unknown human relative. This made me wonder, is it known how much DNA can differ ...
1
vote
1answer
38 views

During DNA foot-printing, what is the purpose of radioactively labeling only one end of the DNA fragment?

I read that during DNA foot-printing analysis, DNA is radioactively labeled on one end before being cleaved by DNase 1. I understand that it is labeled so in order to locate the fragment on a gel, but ...
0
votes
2answers
21 views

What's the difference between the terms “gene map” and “genome”?

It seems some sites arbitrarily restrict "gene map" to only a single chromosome, but others don't. Supposing we don't restrict it to just a single chromosome, is it different from "genome"? Are these ...
0
votes
0answers
38 views

Linker DNA and Genetic Expression

So I was reading on linker DNA, and the textbook only describes it in terms of structure. I was wondering if linker DNA can ever contain genes, and if it can, whether it will always be expressed or ...
0
votes
1answer
54 views

How does the helicase enzyme break the hydrogen bonds between the strands of DNA?

I know helicase breaks the hydrogen bonds between the strands of a DNA, but how is this done? Does it put an ion between the strands of the nucleic acid so that the bond breaks apart itself or is ...
1
vote
4answers
108 views

Is variation a result of Evolution?

We know that the DNA copying mechanism that replicates DNA during cellular division is not 100% accurate and the resultant errors are the source of variation in the members of a population. At the ...
2
votes
0answers
27 views

What is the status of the cfDNA ends?

I am working on a protocol to ligate cfDNA, extracted from blood, into some vector. I have looked into the literature but I cannot find any detail about the status of the ends of the cfDNA. Are they ...
2
votes
2answers
109 views

Can 1.5 gigabytes encoded in the human genome really account for the complexity of a human being?

I read the human genome is 1.5 gigabytes in size. Thats actually not a lot; Photoshop probably takes more space. Mac OS takes 10+ gigabytes of space. Also, the genome is 1.5 gigabytes when counting ...
4
votes
0answers
46 views

Who invented dN/dS?

I am writing a paper, and I want to refer to the original paper that coined the term dN/dS (or Ka/Ks for that matter). I have found early works on dN and dS (like Miyata and Yasunaga 1980), but cannot ...
1
vote
4answers
91 views

Why do mutations not take place in mRNA of higher eukaryotes?

Is it because it is too short-lived to be mutated? Both DNA and RNA are nucleic acids so how is mRNA protected? RNA viruses undergo mutations to evolve so I guess it is not immune to mutations
5
votes
1answer
73 views

A little help understanding DNA supercoiling

I am studying molecular biology from Lewin's Genes XII and got confused in the supercoiling topic. Since then I read from several other sources and so far understood the following. However, I can't ...
-1
votes
1answer
62 views

How to find which genetic pattern is responsible for structure of a cell

I studied that DNA are blueprints that describes an organism. How do I learn more specifically about DNA regions responsible for storing structure of a cell. By Structure of a cell I meant to ask ...
0
votes
1answer
46 views

Separate DNA fragments with very different size (oligo and lambda-DNA)

I am running a ligation reaction to one of the sticky ends of lambda-DNA. The oligo for the ligation is 25 bp (10x excess), whereas lambda-DNA is 48 kbp. I would like to recover the lambda-DNA and ...
-4
votes
1answer
40 views

In a Chromosome, 2 nm is the length of what?

this figure comes from the nature 2 nm at the top right hand corner is the length of what?
-2
votes
1answer
41 views

DNA and Genes, which consists of which? It seems that the hot answer on quora is different to the nih post

This quora's answer has got 8.3k views and 20 Upvoters. "Genes are a part of the DNA." per nih, "Genes are made up of DNA, which is telling the truth." in my understanding, the quora version ...
1
vote
0answers
31 views

Is presence of air necessary for silica gel to absorb moisture?

I am a biologist currently doing field work where I need to quickly dry leaf samples using silica gel crystals. I use the orange indicating kind that are 2-4mm in size. The setup is like this. I ...
2
votes
1answer
44 views

Insertional inactivation using pBR322

I have questions regarding "selection using insertional inactivation". In a typical DNA recombination experiment using plasmid pBR322 where a new gene in inserted in the place of tet gene, it is ...
-2
votes
1answer
45 views

Difference Junk DNA and Pseudogenes [duplicate]

1-Are Pseudogenes and Junk DNA both Non-Coding DNA or they are different entity? How much Pseudogenes & Junk DNA do we have respectively? 2-I read that Non-Coding DNA has functions, my question ...
1
vote
0answers
42 views

Is UV radiation more likely to cause mutations during mitosis?

According to Life: The Science of Biology (10th edition), UV radiation might cause the formation of pyrimidine dimers, which are the primary cause of skin cancer in humans. Are mutations more likely ...
0
votes
1answer
32 views

Can I use a basic compound microscope to analyze the ploidy of plant chromosomes?

So, I'm not really any kind of trained botanist. But I do have two things: some dandelion seeds from France, and, collecting dust in my garage along with related accessories, this thing. Normally, ...
4
votes
1answer
110 views

Explain to a layperson how cigarettes smoke might cause cancer

I have a very intelligent friend who is a light smoker, and also a Biology layperson. I wondered whether understanding exactly how cigarettes smoke can cause cancer, might encourage him to smoke less ...
4
votes
1answer
125 views

Replacing, instead of repairing, DNA

I've been doing some light reading on DNA damage theory of aging. One of the main ideas from that theory that I got is that the accumulation of damage in our DNA is one of the biggest causes of why we ...
1
vote
0answers
52 views

Why is double stranded DNA considered to be one molecule? [duplicate]

Wikipedia, for example, refers to DNA as "a" molecule, not two separate molecules forming a double-helix structure. Isn't this technically incorrect? There are two separate polynucleotide strands (...
1
vote
0answers
81 views

Number of DNA strands per chromosome

As I was reading Griffith's Introduction to genetic analysis this evidence was provided for single DNA makes single chromosome. Eventually geneticists demonstrated directly that certain chromosomes ...
2
votes
1answer
46 views

What is the difference between DNA vs RNA Editing in the context of gene therapy?

As a someone with beginner knowledge on biology, I have come across the terms "RNA editing". Take this paper for example : RNA Editing with CRISPR-Cas13 From my understanding, DNA -> RNA -> Proteins ...
0
votes
1answer
28 views

How do primers anneal to ssDNA?

In a PCR type protocol, the high temperature stage of the cycle will cause dsDNA to denature, as well as any annealed primers. At the lower temperature the denatured dsDNA will remain denatured. As ...
1
vote
1answer
70 views

Do all restriction enzymes have palindromic recognition sites?

I am trying to find out the requirements for a segment of DNA to be the recognition site of a restriction enzyme. Acording to the article on Restriction Enzymes in Wikipedia, "many of them" (...
2
votes
1answer
82 views

Can radiation exposure cause cancer later in life even if no traces of radioactive material are present in the body anymore?

I had a long-lasting debate with a friend of mine about the Fukushima incident. The question that we tried to solve was if radiation or toxin exposure can cause cancer later in life even if no ...
0
votes
2answers
68 views

Can something cause both breaks and cross-links in DNA?

A double strand break in DNA is exactly that: the strands of DNA are severed. A cross-linkage occurs when something forms a covalent bond between two nucleotides in DNA. However, is it possible for ...
1
vote
1answer
90 views

What do lower case nucleotides mean in this gene sequence?

The following table (image linked below) shows promoter sequences recognized by different sigma factors. The sequence given for, e.g. sigma B is "GTTTaa"; why are the "a"s lowercase? (from "A sigma ...
1
vote
0answers
28 views

Genes of the electron transport chain

Where are the genes of proteins that make the electron transport chain of mitochondria?(are they in in the nucleus or they are in the dna of the mitochondria itself?) Thanks for this answering system ...
4
votes
2answers
180 views

What did Francis Crick and James Watson discover that Rosalind Franklin didn't?

I've recently been introduced to the history of DNA research from Miescher to Franklin, Crick, and Watson, and I've found that Franklin had figured out a great many number of things out that Crick and ...
0
votes
0answers
23 views

Is it possible to Clone a Dinosaur with a full strand of their DNA? [duplicate]

If you have a full strand of Dinosaur DNA would it be possible to make it living and hatch a dinosaur? Or would it be a failure? Could you use a bird or alligator, for replacein
0
votes
1answer
57 views

Where can I find DNA decryption research? [closed]

What is the name of the science that studies the mathematics of DNA? Where can I learn about maths, statistics, types of code, numbers, patterns and graphs for genes and information found in DNA?
3
votes
2answers
91 views

Can DNA be flattened?

DNA is always shaped like a double helix. But could you flatten the double helix (which is essentially just a twisted ladder) and would DNA still be able to duplicate and control cells?
2
votes
0answers
17 views

Need help to determine % difference between DNA-strand from two different haplotypes. Known nucleotide diversity and more

Backround: 229 DNA sequences 493 bp in length Haplotype diversity: 0.9956 Average number of nucleotide differences: 12.50544 Polymorphic sites: 145 Nucleotide diversity: 0.02426 Is it possible ...
1
vote
2answers
41 views

Phenotypes caused by mutations in mitochondrial DNA?

Will mutations in mitochondrial DNA necessarily affect phenotypes? I have some cursory knowledge of serial endosymbiotic cell theory, and find it difficult to consider that the DNA of the former ...
0
votes
1answer
19 views

Is newly produced sperm healthy if there was previous DNA damage?

I read that sperm cannot repair DNA damage. So does this mean that if your sperm has DNA damage, then all of your sperm (whether present or future) has DNA damage? Or does it just mean that the ...
2
votes
1answer
62 views

Is DNA from more parents (than two) better for the fitness of the offspring?

I'm designing a system (a computer system actually) and (a whole while ago) I spoke with a friend about it and he had this opinion: If you combine DNA of more parents (than 2) it's better for the ...