Questions tagged [endocrinology]

The area of physiology dealing with the production and effects of hormones.

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Why do beta-1 and beta-2 adrenergic receptors result in two completely different effects (though both use Gs pathway)?

$\beta_2$ adrenergic Receptors are $G_s$-coupled 7-TM proteins. Considering that $G_s$ , by activation increases $[\text{cAMP}]_\text{cytosol}$ which inhibits MLCK of smooth muscles (and causes ...
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What controls the size of breasts?

I am not a biology student, just a curious person. To be specific, I'm talking about female humans. I know that it might apply to other mammals. What controls the size of breasts? I have heard about ...
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Why severely increased Ligand (eg Hormones) concentration downregulates the Receptor?

As an example continuous high blood level of GnRH in humans causes a suppression of LH and FSH. This is due to the fact that increased GnRH downregulates GnRH-Receptors . My question is how this is ...
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When assessing a threat, does the amygdala compare the stimulus to memories of the amygdala or the hippocampus?

Two excerpts from the one article. My understanding of this excerpt is that the amygdala is using its own memories: The amygdala learns how to respond to various stimuli based on it’s reference to ...
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Steroid hormones: how do they travel through the cytoplasm (not just the blood plasma) if they're hydrophobic?

I get that steroid hormones need hydrophilic plasma protein carriers (eg albumin, TBG) to travel in the plasma because they're not soluble in the plasma. However, I don't see any sources talking about ...
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Glycogenolysis & Gluconeogenesis

Is glycogenolysis and Gluconeogenesis is the same in the terms of product formed? This doubt arrived when I was attempting true & false and the question was Glucocorticoids stimulate ...
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Mandibular angle steepness/curve — adjustment possibilities from a biological and physics/mechanical standpoint

Is there any known way by anyone on here who could postulate a method by which the steepness of the mandibular angle can be altered to a lower degree with the concepts of morphogenic, bioenergetic/...
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746 views

What is the effect of TSH on the calcitonin?

I know that TSH is released from the pituitary gland and it motivates the thyroid gland to release thyroxine, and calcitonin is released when the calcium level is high in the blood, but is calcitonin ...
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489 views

Genetic engineering for insulin production

In order to put human DNA inside a bacteria in order to have it create Insulin, from what type of cell would you need to take the gene for insulin? I thought it should be from any somatic cell, since ...
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Why isn't there T2 thyroid hormone?

The follicles in the thyroid, intake iodine and bind them onto the tyrosine rings (attached to the thyroglobulin). This produces either MIT or DIT (tyrosine rings with 1 or 2 iodines attached ...
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Silly question about two human mechanisms: induced “REM dreams” by masturbation?

First of all, I'm a layman concerning Biological discussion. Well, my question is simple: is there any relationship between the hormones liberated by masturbation and REM phase of sleep? I'm ...
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How are Thyroid Stimulating Ab destroying thyroid tissues?

I was reading about Graves' disease, which is an autoimmune disorder. I read a few books, including Endocrinology by Hadley and Levine, and websites where they mentioned that the antibody named TSAb (...
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Enlargement of thyroid gland

Why does thyroid gland enlarge both in hypothyroidism and hyperthyroidism? Hypothyroid goitre is due to lack of iodine in diet and hyperthyroid goitre (Exopthalmic goitre, Grave's disease) is due to ...
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Which hormones, metabolites, or other molecules build up as the day progresses, other than melatonin and adenosine?

Melatonin and adenosine reach peak levels around midnight/bedtime. I was wondering what other molecules also buildup as the day progresses. Particularly molecules that affect the CNS and/or immune ...
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1answer
170 views

Does estrogen increase muscular growth in females?

Regarding humans it is said that most psychological effects caused in men by testosterone are caused in women by estrogens. There are many studies on that, particularly regarding temporary shifts of ...
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How does exercising/starved muscle import glucose (released by liver)?

Adrenaline releases glucose from the liver during sport or if starved. This glucose goes to the blood through GLUT2 transporter. But how does it get transported into the muscle cells? GLUT4 is the ...
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What are cells not affected by hormones called?

Cells that are affected by hormones are called target cells which have their own receptors that listen to signals. I'm unsure of the actual name of cells that are not affected by hormones, I tried ...
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Do human beings have pheromone receptors?

What is the current consensus on whether or not humans have receptors that detect pheromones? If there are purported receptors, in what anatomical areas are they located? With what organ systems do ...
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Endocrine system in frogs, interstitial pressure gradient prevents absorption into blood?

Frogs have an elastic interstitial space and the pressure gradient to capillaries prevents reabsorption (Hendrick, 2013). Does this mean that diffusion of hormones into capillaries becomes a problem, ...
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Why do patients with type 2 diabetes not show the body wasting seen in type 1 diabetics?

Type 1 diabetes results from the destruction of the cells in the pancreas that produce insulin, while type 2 diabetes is characterized by so-called "insulin resistance", presumably a reduced ...
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Why is the thyroid gland in the neck?

The neck seems like an odd place for it. All other neck anatomy must interface between the head and abdomen (trachea, esophagus, circulation, spine etc). Surprisingly I have not been able to find ...
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What is the function of dreaming? Does a particular hormone secretion interfere with dreaming? Why do some people dream more?

I'm really interested to know when we are sleeping how a series of stories come to our mind that we called this process dreaming. If you know a useful article on this topic, please tell me thanks.
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Why is insulin given in type 2 diabetes?

For this reason "insulin insensitivity", or a decrease in insulin receptor signaling, leads to diabetes mellitus type 2 – the cells are unable to take up glucose, and the result is hyperglycemia (an ...
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1answer
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Why would it be beneficial for cortisol and corticosterone to exhibit pronounced anti-inflammatory activity?

These questions are always a little silly (as we will never truly know), but it always struck me as odd that corticosterone and cortisol exhibit pronounced anti-inflammatory activity. Because these ...
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Why is angiotensin converting enzyme localized in the lungs

I understand that it's also found elsewhere, such as in renal capillaries, but I can't see logic behind it being located in the lungs. Isn't ACE's function, through making more angiotensin II, causing ...
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Differences between neurotransmitters and neuromodulators

According to the Wikipedia article on neuromodulation a neuromodulator can be conceptualized as a neurotransmitter that is not reabsorbed by the pre-synaptic neuron or broken down into a ...
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1answer
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Are hormones antigenic?

I have been asked whether hormones are antigenic. I would have to think that the answer is no because they are used as various drugs such as FSH in infertility treatments without the need of ...
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Can ovulation and menstruation occur simultaneously?

Is that possible that ovulation happens in the time of actual menstrual haemorrhage in human females - let say in a case that woman has 21 day cycle and her menstrual period is 7 days? If yes, does ...
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Target cells of adrenaline?

I have been thinking about how adrenaline increases blood sugar levels, but have not been able to find an answer to the target cells. Does it affect the hepatocytes and muscle cells, like glycogen? ...
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Effect of angle of light on flowering of plants

I understand that the angle of light changes the direction of growth in plants (phototropism), but would the angle of light have any effect as such on the flowering of plants? Thank you!
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Endocrinology - cortisol and its effect on growth

If cortisol has permissive effect on growth hormone then why does patients with Cushing syndrome are of stunted growth ?
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How does the body make sure that Vasoactive Intestinal Protein reaches only the target tissue?

Vasoactive Intestinal Protein (VIP) is a 28 amino acid neuropeptide that has several effects in several systems. These include the cardiovascular system, respiratory systerm, urinary system, immune ...
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After hysterectomy does FSH secretion stop?

This question came in an exam, and my reference book says yes, it does. But it hasn't explained why. If the ovaries are also removed, then the menstrual cycle should stop. In absence of hormones ...
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Why males are more prone to cardiovascular diseases such as heart attacks than females?

I often see more people of males undergoing treatment for heart disease. It is often said that female reproductive hormone (oestrogen) has some cardio-protective action by preventing constriction of ...
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Are neurotransmitters part of the endocrine system?

I was speaking with a substitute teacher of mine, and we were discussing whether neurotransmitters are part of the endocrine system or not. My class just spent an entire semester on the topic of the ...
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Are all endocrine glands associated with common human feelings?

I was looking at endocrine glands and found it interesting that a few of them have some very understandable feelings/mentalities associated with them. In particular: Gonads: arousal/romance ...
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Is atrial natriuretic peptide relased when we drink water?

I know that osmolarity is controlled by the hypothalamus and recover by ADH which reabsorb water. It also can be released when ECV is very low. ECV/salt is controlled by aldosterone/atrial ...
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1answer
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Can stress and arousal be independent?

I'm trying to figure out if it's possible to have a stress response without being initially, or simultaneously aroused. I'm defining stress to be physiological stress (ie. release of cortisol) and ...
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What is the difference between a cytokine, a hormone and a protein hormone?

I'm trying to figure out the difference between hormone, cytokine and protein hormone. It's clear to me that all three are biological messengers, but there seems to some ambiguity and overlap between ...
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Science behind IGF-1 levels increase in milk from rBGH or rBGT treated cows

It is obvious that the use of rBGH or rBGT increases the IGF-1 levels in milk, but from all the research I have done on the internet I did not find why, well yeh cause they inject that hormone but how ...
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Prolactin and Dopamine throughout orgasm?

Dopamine is also known as a prolactin-inhibiting hormone, which keeps prolactin levels in the body in check. However, during orgasm, dopamine is released to make the experience pleasurable. I know ...
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What happens to eyelids when we feel sleepy?

Why is that whenever we feel sleepy, our eyelids start to feel heavier. It is not like we can any time close our eyes and will immediately fall asleep. But, when we feel sleepy our eyelids ...
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1answer
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How are testosterone levels distributed among men and women?

Wikipedia tells me that men have 7 to 8 time higher levels of testosterone than women, on average. Since the hormone is linked with performance in certain athletic events, my hypothesis, which I ...
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Could certain drugs enable one to consistently eat above TDEE or BMR without fat gains?

I heard anabolic steroids and stuff like DNP and ephedrine and etc. can somewhat enable one to eat more and get away with it without much or any fat gain, despite eating more than the body would ...
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What's the difference between releasing hormones and tropic hormones?

I've been reading my textbook and two terms have appeared that, after a bit of looking, I still can't seem to be able to distinguish. Here's what the textbook says (McGraw Hill Bio 12, 2011): After ...
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Is there any way bicondylar/bigonial, bizygomatic or bitemporal breadth can change in adults?

Without cosmetic surgery or etc., are there any cases/example wherein a human adult has had a change in significance regarding these regions of the face? I have seen many anecdotes where people have ...
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1answer
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What's the difference between the neuroendocrine system vs endocrine system?

This is what I have understood so far: Neuroendocrine system involved neuroendocrine cells (also known as neurosecretory cells) that receive nerve impulses by a sensory neuron to release ...
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Hormones - biotic or abiotic

Are hormones biotic or abiotic? I have tried reading different articles, and I've found that it is both, but can that be true?
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How does hyperthyroidism cause diarrhea?

According to Robbin's Pathology, hyperthyroidism leads to an overactivity of the sympathetic system. It also goes on to mention that this sympathetic hyperstimulation in the gut leads to increased ...
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Hormonal terms Somatotrophin or somatotropin?

Are Somatotropin and Somatotrophin hormones the same? It's confusing because when you type in Somatotrophin in google, it says, "a growth hormone secreted by the anterior pituitary gland.", but there'...

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