Questions tagged [gene]

The basic unit of heredity which encodes for some function RNA or protein product.

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1answer
40 views

How does new species come into existence?

The only reason for the creation of new species that I found from the internet is geographical isolation. Are there any more reasons?
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can anybody help me to identify Divergent gene pair from a list of human genes, is there is any connection between Transcription Start Site(TSS)

I am trying to build a computational model to predict the divergent and convergent gene pair from a set of genes. For that, I want to categorize the gene pairs based on gene orientation. From a paper, ...
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What is the real meaning of divergent gene pair?

is it only related with Head to Head organisation of the gene or the TSS distance is also a factor. I am trying to build a computational model to predict the divergent and convergent gene pair from a ...
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What is the full form of Lex A protein? [closed]

Would you please tell me the full form of lexA protein?
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Convolution and deconvolution in gene expression

I am trying to understand the mathematical concept behind convolution and deconvolution in gene expression. Went through various papers but they are way too complicated. Can anyone provide simple ...
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How do I identify and then isolate a Gene that codes for a particular observable phenotype

How do I identify and then isolate a Gene that codes for a particular observable phenotype. It is a novel bacteria and I do not know the gene sequence or the protein that it codes for.
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What are the implications/predictions of the selfish gene theory?

Are there any testable predictions or implications of the selfish gene theory? Or it is just interesting interpretation of the observations/experimental data? If this theory is not falsifiable and ...
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Genes where both a disabling mutation and copy number amplification cause different genetic diseases

I'm trying to make a list of such genes, because they must be tightly regulated. MeCP2 is one - it causes Rett Syndrome with a disabling mutation, but causes MeCP2 duplication syndrome if its copy ...
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What is an allele?

According to the entry for allele in Wikipedia: “An allele is a variant form of a given gene, meaning it is one of two or more versions of a known mutation at the same place on a chromosome.” ...
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What does it mean that the transcript is enriched?

I think I don't get the meaning of "enriched" in the context of genes. What's the difference of gene being "enriched" and "expressed" in the cell?
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Can two proteins activate/inhibit the same gene at the same time?

Suppose there are two proteins inhibiting a particular gene. Its not necessary that both will inhibit the gene at the same time instance right? So if one protein has already inhibited that gene before ...
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Study on Introns?

I am curious whether there has been a study done on the effects of removing introns. Specifically, what happens if you genetically edit a eukaryote genome to no longer contain introns? Or maybe just a ...
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Identify which of the two columns A and B represent gene and chromosome

I am a bit confused on this question in my Textbook (STD 12) and have got all sorts of answers on searching it but I am still not able to comprehend it literally. Can someone answer this and explain ...
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Are any genes over a billion years old?

Are there any genes (for any organism) for which we can say with confidence that they are over a billion years old?
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Marigold Colors

Is it really true that Marigolds have three colors (Blue, Purple, and Rea) and that they are controlled by two genes? I saw this claim in one of my classes.
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Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

All humans have the same sort of proteins in our bodies. Take haemoglobin for example. Is the gene coding for haemoglobin in my body identical to everyone else's gene or is there slight variations ...
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What is the average number of alleles per gene we have today?

Yesterday I was making some calculations, and I started to wonder the average number of alleles per gene the human species have today. The best question would be how many mutations per base or how ...
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Consider gene is countable, can anyone give a concrete example of “a gene”?

gene is a countable noun but people always say genes, so what is A gene? for instance, Each chromosome contains many genes, so, which part of the chromosome of Escherichia coli could be ...
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Need help in identifying and understanding the origin of an expression variant

We usually denote the origin of a mutation as either somatic or germline. This information is usually available in certain databases such as CIVIC, ClinVar, COSMIC etc. But when we come to variants ...
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Do human genes get affected by irregular sleep and other factors

I'm new here so please go easy on me. Do our genes-the ones that carry our appearance, intelligence and other traits get destroyed or lost due to irregular sleep, excessive body heat, smoking, ...
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Where can I find DNA decryption research? [closed]

What is the name of the science that studies the mathematics of DNA? Where can I learn about maths, statistics, types of code, numbers, patterns and graphs for genes and information found in DNA?
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Emergence of novel protein interactions by mutation of amino acids

Are there any examples of proteins that, without coming from a recent duplication event, underwent a mutation(s) that caused it to have a novel interaction with a new ligand, substrate, other protein ...
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Why eyebrow growth stopped after it has specific length?

When comparing with hair that grow forever after we cut it, why eyebrow not. what gene measure current length of eyebrow so it stop to grow after specific length.
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What is the difference between Regulatory Gene and Modifier Gene?

If both controls the expression of another gene by physically or genetically interacting with the target gene, which attributes make "Regulatory gene" different from "Modifier gene" or vice-versa?
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Is there a known mutation of an insertion type that prevents being infected by a virus?

Recently there was big news about the mutation CCR5 delta 32, that prevents HIV from infecting white blood cells, that was a deletion type of a mutation. Do we know of an insertion type of mutation ...
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Does the law of independent assortment apply to homologous chromosomes or alleles, or both?

My textbook is giving me two definitions 1st def: "random orientation of homologous chromosomes at the metaphase plate in meiosis 1." 2nd def: "alleles for one gene separate into gametes ...
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What does Ercc1-/- / DAT-Cre+ mean?

I really need to know what Ercc1-/- / DAT-Cre+ mean. I think the 1st part means that the mice don't have the Ercc1 gene (knockout). But what about DAT-Cre+? This question arised from reading the ...
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How can inbreeding be used for selecting mutations?

I understand that inbreeding, after a number of generations of crossing genetically related individuals eventually yields homozygotes, however I can't seem to understand how it can be used for ...
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Identifying statistically significant gene rich and gene poor regions

I am just wondering If there any adapted way of Identifying significant gene rich and gene poor regions in each chromosome for a given genome say mm10?
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If bacteria with recombinant DNA molecules do not survive in gene cloning, how they can be grown into a colony after being isolated?

This is as far as my understanding of gene cloning goes. Let's say that the plasimd (vector) in the bacteria contains an ampicillin resistence gene. Through restriction enzymes, the ampicillin ...
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Gene frequency — database/site

Is there any free database when one can check the gene frequency in a healthy population? For example I would like to check it for genes like BIN1, CLU or CR1. On the English Wikipedia I found a gene ...
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Can Tajima's D and other population genetic tools be used to copare Arabidopsis ecotypes?

I am currently investigating 2 genes in Arabidopsis taliana that are a product of a recent duplication even (observable from synteny and phylogenetic analysis). In addition to the molecular and ...
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Are modern gene-editing techniques capable of creating genetically-superior versions of humans? [closed]

Can we alter the DNA in, say, a small-framed, low muscle mass male to those of elite bodybuilders? Can we alter the DNA sequence that stops balding and hair loss? How about the genes responsible for ...
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Question: What is CINWntUp and CINnormL?

What is CINWntUp and CINnormL? I read a paper that uses this two things as classes but Im not sure what they represent. I imply that CIN is referring to Chromosomal instability but I don't know what ...
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Are androgenic-anabolic steroids a form of gene editing?

Is taking AAS a form of gene-editing? Steroids alter genes in some way since they allow people to build more muscle than what's naturally possible -- so they sort of "break" natural genetics somehow. ...
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Gene expression: which allele is considered?

For human beings, we have two copies of each gene inherited from the parents. The question is, when referring to gene expression, which copy (or allele) is considered?
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Confusion about a gene's description

I have a very basic biology question. I am reading the description of gene FAM166A here, and I have no idea what "sequence similarity 166" means. What does 166 stand for, what is this gene's sequence "...
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How do you define a gene list?

So I wrote in a chapter that I will be checking for publications with gene lists in them. I got a comment asking "How would you define a gene list and what criteria did I use". I know that gene lists ...
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Functional Difference between the Distal Promoter and Enhancer Region

According to the Wikipedia article on eukaryotic promoter regions, the distal promoter is: Anything further upstream (but not an enhancer or other regulatory region whose influence is positional/...
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Query regarding KEGG KGML pathway files

With respect to the the Wnt pathway in KEGG, the KGML file of this pathway has description of each interaction between a pair of genes. These interactions are designated in the form: ...
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How to do a blast search for similar sequences?

Tried doing a Blast search for a PPO gene in an advocado genome: https://www.ncbi.nlm.nih.gov/blast/Blast.cgi?PAGE_TYPE=BlastSearch&PROG_DEFAULTS=on&BLAST_SPEC=OGP__3435__73885&DATABASE=...
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How to find a gene sequence?

So I need to learn how to find the sequence of a gene, polyphenoloxidase. Please do not do this for me. Tell me how to approach the problem. I have found : https://www.ncbi.nlm.nih.gov/gene and ...
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Genes and Intelligence

Assuming that intelligence has a genetic component, • do we know which genes contribute to it? and, if so, • can we predict intelligence from genomic analysis?
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how many copies of tp53 (p53) gene do we have?

I just started studying biology so I almost have no knowledge. I learned about the tp53 gene and I just wanted to know how many copies of tp53 gene we have?
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Which gene regulatory network is the largest in human?

What is the maximum number of nodes involved in any gene regulatory network and which network is it, provided its from human?
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Can gene-gene interactions result in gene expression?

I am building a project on Inferring Gene Regulatory Networks using ARACNE and PCA-CMI algorithms, and the input to these algorithms is taken from the DREAM3 challenge. The format of the input data ...
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What is linkage?

If two genes are on the same chromosome, are they always “linked”? What if they are more than 50 cM apart? Then they would follow Mendalian pattern of inheritence. So are they still linked?
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Do chromosomes change with time?

An offspring is 23 chromosomes of mother and 23 of father, if one of the mate learns say music after the birth of their first child— will their second offspring have better music skills than former? ...
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How should I interpret for example AA result, when SNPedia only has CC/CT/TT listed? [closed]

I don't know how to properly formulate this question because I'm new to this, so please edit this if you can... For example when I would check SNPedia for rs gene, it would have listed CC/CT/TT genes,...
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Isolating gene of interest from a large strand of DNA [closed]

I was always confused about this in class and never learned it fully. So say you have 10,000 bp of DNA and you just want to isolate 100bp of specific region(gene of interest) using restriction enzyme. ...