Questions tagged [gene]

The basic unit of heredity which encodes some functional RNA or protein.

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Why does eyebrow growth stop after it reaches a specific length?

When compared to hair that grows forever after we cut it, why do eyebrows stop growing? What genes measure current length of eyebrow to ensure it stops growing after a specific length?
Mohammad Fajar's user avatar
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How to name this bacterial gene when running out of letters?

There's a gene in some bacteria that I have to name. My (very limited) understanding is that for bacteria, naming conventions are based a lot on Demerec et al. 1966 (https://www.ncbi.nlm.nih.gov/pmc/...
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Do some plant proteins have no domains?

I've always been under the impression that all proteins consist of at least one domain (with the exception of intrinsically disordered proteins). However, I've come across some things which challenge ...
arara's user avatar
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Number of alleles' variations in a mushroom that has over 20,000 sexes

I am trying to understand the mating behavior of a particular species of fungi known as Schizophyllum commune, or the split-gill. I found a blog post that explains the mechanisms that define the ...
Joonthan Wimbed's user avatar
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CRISPR Knock in

Using the CRISPR/Cas9 technology, it is possible that after inducing a DSB with the Cas9 endonuclease guided with an RNA designed by the user and using a template DNA, get a desired Knock-In (KI) by ...
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Gene Name Finding

X8HS20 - please help, I am not able to find the proper name or function of this gene in any database - can someone kindly help to figure out what it is ? I hypothesize that it is some gene of ...
Stack Man's user avatar
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What are the causes of gene amplification in archaea?

I was studying this article about Genome Sequencing of a Genetically Tractable Pyrococcus furiosus Strain Reveals a Highly Dynamic Genome in order to try to extrapolate some features that could ...
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Can two proteins activate/inhibit the same gene at the same time?

Suppose there are two proteins inhibiting a particular gene. Its not necessary that both will inhibit the gene at the same time instance right? So if one protein has already inhibited that gene before ...
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Does the law of independent assortment apply to homologous chromosomes or alleles, or both?

My textbook is giving me two definitions 1st def: "random orientation of homologous chromosomes at the metaphase plate in meiosis 1." 2nd def: "alleles for one gene separate into gametes ...
BlueMagic1923's user avatar
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Can Tajima's D and other population genetic tools be used to copare Arabidopsis ecotypes?

I am currently investigating 2 genes in Arabidopsis taliana that are a product of a recent duplication even (observable from synteny and phylogenetic analysis). In addition to the molecular and ...
Igentile's user avatar
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Functional Difference between the Distal Promoter and Enhancer Region

According to the Wikipedia article on eukaryotic promoter regions, the distal promoter is: Anything further upstream (but not an enhancer or other regulatory region whose influence is positional/...
Hawkeye's user avatar
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Which gene regulatory network is the largest in human?

What is the maximum number of nodes involved in any gene regulatory network and which network is it, provided its from human?
girl101's user avatar
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Gene networks in insects

I am working on gene networks and I currently have the honey bee gene network to work with. What I am missing is a gene network that I could compare it with. Could you please guide me to a database/...
The Last Word's user avatar
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Familial Hypercholesterolemia

Why does Familial Hypercholesterolemia shows autosomal dominant pattern? Let us take that there is mutation in LDL receptor gene, it is said that: The LDL receptor gene is located on the short arm ...
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Is there any technique can quickly expand one set of cell chromosomes?

Assume a cell type is very scarce while isolated out and hard to expand in vitro, and I wanna have more of its chromosomes, is there any technique , in vivo or in vitro or ex vitro, any would count, ...
Xin Liu's user avatar
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What is the upper limit of number of SNP based mutation in any protein?

I want to know if there is any upper limit of, how many point mutation a protein can have because of disease or nsSNPs? The general studies only focus mostly on a single or double site mutation of any ...
Devashish Das's user avatar
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How to find name of the gene

Considering the kegg page, this page contains the description of the gene Edwardsiella tarda EIB202: ETAE_0074 . Now this gene has a name given in the page as : wabG. Now considering another gene 1 ...
girl101's user avatar
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How to identify a pseudogene to a specific protein coding genes?

Pseudogenes are those sequences in the genome that bear similarity to specific protein coding genes, but nevertheless are unable to produce functional proteins due to existence of frameshifts, prema- ...
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GO term for orthologous gene IDs

I have a list of orthologous gene IDs from the first supplementary file in here. The gene IDs are of the following type: ...
abcdef's user avatar
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His Tag location in gene circuit

I am part of an undergraduate research group and we are trying to produce a protease in an E.coli gene circuit. We are not sure where to place the His tag in our circuit. The sequence is ...OmpA(gene)-...
Kelly Eckartt's user avatar
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Immediate Early Genes during sleep

In Neuroscience 3rd ed by Bear et al. on page 607, immediate early genes are described as related to changing synaptic strength, yet have decreased expression during sleep. The explanation given is ...
SorcererofDM's user avatar
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Gene Mapping - Please explain in Lay terms

Taking an AP bio course, and for some reason I cannot comprehend the mechanism of how one determines the location of alleles on a chromosome. The math is simple and I can memorize it, but its bugging ...
Morgan Harkins's user avatar
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What is the most accurate polygenic score for Alzheimer’s disease?

To date, which polygenic score (i.e. which study) has produced the largest effect size for Alzheimer’s prediction in out-of-sample validation?
BigMistake's user avatar
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What gene does the RAN-2 antigen correspond to?

In many papers, immunopanning is performed against RAN-2, which stand for "rat neural antigen-2" (some examples). It seems to have been first described by Bartlett and colleagues in 1981 and ...
Alexlok's user avatar
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How do i find and download targets of drugs which are in DrugBank?

Recently, I am focused on drugs and their interactions. But since I am new in this field, using experts experience would help me a lot. I have downloaded DrugBank xml file from DrugBank website and ...
Orca's user avatar
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What actually causes temporal isolation

Temporal isolation is caused when members of the same species are available to reproduce at the same time. How is such a phenomenon even possible, is it caused by mutations which lead to a certain ...
Malhar Kookada's user avatar
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Do homologous chromosomes have same rates of gene expression in a cell?

I was googling around and found only articles related to XY differences in expression. Can you please clarify if homologous genes/chromosomes have about the same levels of expression in a cell or one ...
IlliakaillI's user avatar
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390 views

Using the law of independent assortment, why can't heterozygous parents make identical twins?

In a case where two parents are heterozygous, why can't any pairs of their children be identical twins? As the question asks, I tried to explain this using the law of independent assortment, which ...
John Liu's user avatar
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What is a good book to start with if I'm interested in Gene clustering analysis?

As a beginner, I would like to learn more about gene clustering analysis, namely discovering groups of correlated genes potentially coregulated or associated to some conditions or finding patterns in ...
Bianca I.'s user avatar
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Microarray experiment validation meaning

I have a quick question: what does microarray experiment validation mean ? I was reading a paper in which they say that the data of the experiment show that the 3 genes radB, dp1 and dp2 are co-...
Manuela's user avatar
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Is the mRNA produced constant during time?

I am doing a statistical data analysis of a dataset of P. Furiosus cells exposed to gamma radiation. For the samples exposed to gamma radiation, I have the values of mRNA produced over time. For the ...
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How do I identify and then isolate a Gene that codes for a particular observable phenotype

How do I identify and then isolate a Gene that codes for a particular observable phenotype. It is a novel bacteria and I do not know the gene sequence or the protein that it codes for.
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Genes where both a disabling mutation and copy number amplification cause different genetic diseases

I'm trying to make a list of such genes, because they must be tightly regulated. MeCP2 is one - it causes Rett Syndrome with a disabling mutation, but causes MeCP2 duplication syndrome if its copy ...
Mike Flynn's user avatar
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Study on Introns?

I am curious whether there has been a study done on the effects of removing introns. Specifically, what happens if you genetically edit a eukaryote genome to no longer contain introns? Or maybe just a ...
alpha-tetramer's user avatar
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Is there a known mutation of an insertion type that prevents being infected by a virus?

Recently there was big news about the mutation CCR5 delta 32, that prevents HIV from infecting white blood cells, that was a deletion type of a mutation. Do we know of an insertion type of mutation ...
Mocas's user avatar
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Gene networks for different tissues?

I currently work on gene networks and specifically, I analyze the brain gene regulatory network of an insect to understand its sexual behaviour. During a recent presentation, I got asked this question ...
The Last Word's user avatar
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109 views

Organ secretions

If an animal secrets an enzyme from an organ that is entirely dedicated for the same secretion, can one or cannot one just use the gene coding for that protein to obtain the protein in vitro. How much ...
MPG's user avatar
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minimum ratio of the shortest isoform to the longest one derived from one same parent gene

I want to know what is the minimum percentage of the shortest isoform/transcript to the longest one that derived from the same parent gene? Does it have organism specificity? What is the function of ...
pengchy's user avatar
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1 answer
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Mutated and unmutated PCR product

If I have a mutated colony containing the fusion protein, mCherry instead of the stop codon TAA, and an unmutated colony which does not contain the protein. Why will the PCR products of the two ...
user59188's user avatar
0 votes
1 answer
90 views

Critical discussion: Gene expression and systems biology allows us to understand the control of complex traits

I'm having a bit of trouble tackling this question. Any help on what I should write about or the points I should mention would be much appreciated. I keep seeing articles about eQTL and QTL are these ...
Sarath K's user avatar