Questions tagged [genetics]
Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.
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Quantifying the Genetic Basis of Complex Diseases
This question is very general. So in general, there are 2 types of diseases for which we understand "causality" very well: 1. Infectious disease, where there is some etiological agent that causes the ...
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1answer
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PCR markers for C57B6
Do you know any primers that can be used to genotype mice and check if they are still C57B6? I'm concerned about genetic drift in my colony. I bought a breeding pair 3 years ago and expanded. I wanna ...
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Parthenogenesis vs. Fertilization. Is a polar body different from an egg?
In Parthenogenesis that happens by automixis "the replication of an egg by meiosis and the transformation of the haploid egg to a diploid cell occur by fusion with a polar body." =https://www....
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Effect of myelination on inteligence in cephalopods
Cephalopods are known for their unique intelligence compared to other invertebrates.
The number of neurons of cephalopods is of the order $5*10^8$, similar to dogs. Humans have about $10^{11}$ ...
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2answers
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ELI5 what is true breeding?
In "Variation under Domestication", Darwin makes several references to the concept of true breeding:
They believe that every race which breeds true, let the distinctive characters be ever so slight,...
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What steps are required in order to obtain haplogroup data from a DNA sample? [closed]
How can one obtain haplogroup data from a DNA sample? What tools would be required for the purpose?
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1answer
17 views
Analysis of post transplantation lineage tags
I'm having some trouble understanding some bits of a study, mostly about the Sleeping Beauty system and TARIS model, from this paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408613/
I ...
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1answer
61 views
Are there animal species where some females have greater amounts of male-associated qualities than average males?
In the human species, some women ( a meaningful, though not large percentage) are taller and stronger than the average man.
Is a similar thing true in the animal kingdom? Are there some meaningful ...
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29 views
Understanding HSV1 - What could be an appropriate/common path? [closed]
This question could be off-topic, but I will try to make it fit.
I have no biology background at all but want to get a more detail understanding of Herpes Simple Virus 1 (HSV), how it works, how it ...
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2answers
50 views
What is the substance that tumors release that stimulates growth of blood vessels but suppresses its release from other tumors?
I'm currently in high school and I am working on a cancer research project. My project consists of a cancer, and different ways to treat it. I have a set of benign tumor and I was thinking of ...
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40 views
How can we say that a gene is spacio-temporally regulated?
Gene expression is depending on the space and time of the cell. How can we distinguish the function of a gene without a chance of changing its expression? And also how is it possible to find the exact ...
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What is maximum growth rate possible for tree if we could genetically modified it?
If we genetically modified tree to have it grow as fast as possible and consume carbon mass as much as possible. I want to know the uppermost limit for it to grow in each year around the tropical area ...
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What controls specific gene silencing during cell differentiation?
I am intrigued by the fact that all cells of our body use the same DNA. How do the cells differentiate during the post fertilisation divisions?
I read about gene silencing, which can be an answer to ...
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2answers
86 views
How does a drastic change to the genome persist and spread?
I just read the article on songbirds in the November, 2019 Scientific American. The article explains that songbirds have an extra chromosome, called GRC (germ-line restricted chromosome) that other ...
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3answers
124 views
How Incomplete dominance can be explained at molecular level?
What is exactly happening at the molecular level when two genes constitute incomplete dominance? Whether the protein formed from each of the genes constitute a new protein having a different function ...
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26 views
Way to analyze the functional relevance of human mutation in vivo
In the literature I „found“ a pointmutation in the protein coding sequence of an enzyme subunit to be a risk factor for a certain disease. It is not known whether the mutation leads to loss or gain ...
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26 views
Study on Introns?
I am curious whether there has been a study done on the effects of removing introns. Specifically, what happens if you genetically edit a eukaryote genome to no longer contain introns? Or maybe just a ...
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1answer
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Genetics and Heredogram - Proving the teacher is wrong
I want serious help here. I'm in first year of medical school and I jut had my second test in Genetics. One question of the test gave us a heredogram and asked us what was the most probable type of ...
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Brain evolution in the age of the caesarian
I have just been reading an account of the evolution of human intelligence in Matthew Syed’s recent book on diversity, called “Rebel Minds”.
He is not the originator of this idea, but he suggests ...
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4answers
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Is evolution a means to an end?
In "The Red Queen", Matt Ridley frequently argues that evolution is a means to an end, without providing much explanation for such a big statement.
Is this a fact in biology? Do species mutate their ...
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1answer
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Do some genes follow Rock-Paper-Scissors model of dominance?
Assuming there are at least 3 alleles of the gene $G$ in total - $G_R$, $G_S$ and $G_P$ - is there any gene for which the following is true?
$G_R$ is more dominant than $G_S$.
$G_S$ is more dominant ...
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Rods and Cones functioning in Achromatopsia affected individual
When facing genetically caused Achromatopsia have the cones still been developed by the individual or does the latter completely lack them? I have looked for evidence both online and on some more ...
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2answers
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Identify which of the two columns A and B represent gene and chromosome
I am a bit confused on this question in my Textbook (STD 12) and have got all sorts of answers on searching it but I am still not able to comprehend it literally.
Can someone answer this and explain ...
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1answer
29 views
Why is sickle cell trait expressed in half of all cells rather than all cells containing half-sickled haemoglobin
If sickle cell trait is due to be heterozygous with respect to a single gene mutation on the haemoglobin β-globin chain, why is it the case that ~50% of RBCs are sickled rather than half of the ...
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Which trait does the given Pedigree chart show? [closed]
I have a doubt in this pedigree chart , according to me it should be autosomal dominant. But the ans given is X linked recessive , in the case of X linked recessive one daughter should be carrier and ...
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How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share?
How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share? There are articles online that indicate that humans share xxx% of DNA with Chimpanzees, bananas, and other assorted ...
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1answer
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Is every flower on a plant unique?
I've noticed on my dahlia plants that sometimes there's a flower which looks completely different then the rest . Either color or structural. I dig these bulbs up each fall and keep inside to replant....
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1answer
92 views
What is the genetic reason that this flower has petals of two different colors?
I have two different varieties of the flower, portulaca: one is bright pink, the other is pure white with pink specks at the centre. Recently a flower bloomed which had 50% of the former and 50% of ...
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1answer
155 views
Can primers for PCR be duplicated?
Complete beginner question here, don't laugh:
If I have some primers that have been synthesized, and I am close to running out of them, is there any way to duplicate them / amplify them / synthesize ...
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chromosome 19 and recombination
Im doing a project with structural variation created by recombination within the human genome during spermatogenesis, where im especially examining intrachromatid homolog recombination.
I find that ...
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1answer
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Why does X inactivation happen?
Is X inactivation really important? Why don’t the dominant genes on one chromosome mask the recessive on the other chromosome? This happens in other sets of chromosomes so why exactly does this happen ...
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2answers
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What's the difference between the terms “gene map” and “genome”?
It seems some sites arbitrarily restrict "gene map" to only a single chromosome, but others don't. Supposing we don't restrict it to just a single chromosome, is it different from "genome"? Are these ...
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Linkage terminology in drosophila
Consider two linked loci that are 50+ map units apart. I perform a test cross between a female that is heterozygous at both loci to a male that is homozygous recessive. In this case, the phenotypic ...
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Linker DNA and Genetic Expression
So I was reading on linker DNA, and the textbook only describes it in terms of structure. I was wondering if linker DNA can ever contain genes, and if it can, whether it will always be expressed or ...
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Inheritance percentiles
I am aware that the average DNA contribution from each grandparent is 25%, while the possible range is 0%-50%. I found a source citing 18%-32% as the "normal" range but this was undefined. I assume ...
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1answer
91 views
Example of a virus becoming symbiotic with an organism
The human gut has an indispensably beneficial ecosystem of bacteria. What are the examples of a virus that becomes symbiotic with an organism, or even incorporates beneficially into the genome of the ...
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Does intelligence depend more on environment than on genetic factors? [duplicate]
Many have argued that the test of IQ is simply a test of language. The application of the test consists of asking a number of questions. The person should understand the question presented to them and ...
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Is there any evidence that genes which are associated with physically adjacent structures are located near each other within the genome?
I am not sure if there are individual genes for, say, fingers and if so, would such genes be near the genes that affect hand growth? If not "near" in the Euclidean sense, could there be a different ...
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1answer
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Chromosome naming convention: Why are there chromosomes named “1” and “1A”?
I've been stumbling on multiple genome of birds where there is a "1A" chromosome and a "1" chromosome. For example, the zebra finch has 1A and 4A. What does that mean?
Do you have any resource about ...
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1answer
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The First Polymerase
Knowing that polymerase protein is needed for the transcription of genes, which polymerase is used in the transcription of polymerase protein itself?
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4answers
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Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?
All humans have the same sort of proteins in our bodies. Take haemoglobin for example.
Is the gene coding for haemoglobin in my body identical to everyone else's gene or is there slight variations ...
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1answer
40 views
What does “genetic correlations” mean as opposed to just correlations?
I'm reading the paper "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior". In Fig. 4 shows "Genetic correlations of same-sex sexual behavior with various ...
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What is the average number of alleles per gene we have today?
Yesterday I was making some calculations, and I started to wonder the average number of alleles per gene the human species have today. The best question would be how many mutations per base or how ...
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4answers
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Is variation a result of Evolution?
We know that the DNA copying mechanism that replicates DNA during cellular division is not 100% accurate and the resultant errors are the source of variation in the members of a population.
At the ...
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Animal Transgensis - biological Implications?
I'm writing a report on the biological Implications of Transgensis of a cow which carried the gene for myelin sheath protein in its milk.
I was wondering if anyone would know what sort of biological ...
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1answer
59 views
What is a Singleton Variant
I'm reading a paper that on a population genetics study where they sequence a number of genomes. The study states that 101 Singleton Variants per individual where found. What does Singleton mean?
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1answer
32 views
Do conservation oriented genetic database exist?
Are there any projects for the creation of the international genetic database of all endangered species, so we, at least, have a chance to clone them in the future if our current conservational ...
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0answers
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How does chromosome doubling occur?
Sterile hybrid with genome AB undergoes doubling of chromosome set to form fertile tetraploid with genome AABB.
But since A and B is not homologous, synapsis cannot occur at prophase I, so there is ...
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1answer
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What percentage of Americans have Native Indian ancestry? [closed]
What percentage of americans have native indian ancestry?
I tried to find the answer online and it's difficult to search for.
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1answer
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Tools I can use to find similar genes
What tools are available to estimate the function and purpose of a gene ? I think the right approach is to find similar sequences of genes that we know the function of.
All the information I have on ...
