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Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Is it theoretically possible to safely eliminate most viruses in the atmosphere, hence preemptively cure all the viral diseases?

Could we create a genetically modified virus or bacteria (with inability to mutate into something dangerous for animals) that would quickly spread all over the planet and selectively kill most of the ...
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Mendel heredity [on hold]

can anybody solve this problem with details. Thnx in advance. In some type of pigs, the allele of black hair is dominant (B) and the allele of white hair is recessive (b). If two pigs of the following ...
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1answer
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On which chromosomes were the traits studied by Mendel?

In his experiment with peas, Mendel mainly studied two traits : yellow/green colours and round/wrinkly shapes. I've heard that the pea genome is very large and its sequencing is a challenge. However, ...
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(answered) reciprocal cross vs test cross [on hold]

A reciprocal cross is one between a male and a female parent, but is this just a subtype of test crosses? Nevermind, reciprocal is to determine if trait is sex linked and test cross is for whether ...
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1answer
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Basic questions about human genome project

The "human genome" was sequenced by the Human Genome Project around 2000. But I don't understand what was done and what its significance is. Questions: Wasn't a single person's genome sequenced? I....
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what would be the genetic risks of marrying a distant ancestor?

Suppose that the human life span is multiplied a few times. If the human lifespan was multiplied two to three times age 120 to 240 would be roughly equivalent to age 60 to 80. Thus it would be ...
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EJ138 bladder cancer cell line

My question is about EJ138 bladder cancer cell line. Is there any mutation in this cell line, esp in TP53 gene?
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29 views

Can someone help me with the term degeneracy?

As a bit of background, I am not a biologist, I'm just a computer programmer and entrepreneur, I mostly build software applications. Currently I'm involved in a software project with a smart business ...
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17 views

Stem Cells Receptor Protein

Do stem cells (such as bone marrow cells) have any distinct receptor protein on their surface that could potentially be targeted for in vivo gene therapy?
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437 views

Is there logic in this sentence? “Authors discovered a gene as one of the genes evolved through natural selection”

From a news report: PhD candidate Daiki Sato and Professor Masakado Kawata have discovered SLC18A1 (VMAT1), which encodes vesicular monoamine transporter 1, as one of the genes evolved through ...
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1answer
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What is the meaning of Sequestered germline?

What is the meaning of Sequestered germline. I understand the meaning of Sequestered in English but what is its meaning in context of germline. For eg-" female germ cells are Sequestered early in ...
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1answer
48 views

Does a reproductively successful male have the same genetics as a reproductively successful female?

Evolutionarily, using humans as an example, it would make sense that a successful female would produce successful male offspring. If a successful female produced male offspring that weren't successful,...
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44 views

Non-coding DNA correlation with rate of evolution

Non-coding DNA can be helpful in generating useful mutations that can go on to become new features/functionality of an organism. Non-coding DNA also indirectly reduces chances of mutation of useful/...
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why did a dwarf mammoth sunflower grow? [migrated]

I planted at most three dozen mammoth sunflowers last spring. they are all coming up fine, some even blooming. however, one in particular is a tiny, what I would describe as dwarf that is less than ...
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1answer
65 views

are clones siblings to the original?

i have a question about cloning, if a person had his/her DNA sample like hair or blood used to make a clone wouldn't that clone be that same person's brother or sister since they share the same ...
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1answer
93 views

Is the mutation rate in pseudogenes higher than in coding regions?

Coding genes are subject selective pressure that are not present for pseudogenes, that would suggest that pseudogenes have a higher mutation rate than coding regions. If so, how much higher?
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Could the Immune Gene HLA-B27 be gentically altered, snipped, switched off, replaced, edited within the body

Could the Immune Gene HLA-B27 be genetically altered, snipped, switched off, replaced, edited within the body.? Thousands upon thousands suffer immune disease as do I from this highly implicated gene....
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1answer
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Dihybrid cross question

An experiment is set up to study two genes. The two genes assort independently and for each gene the expression of alleles involves complete dominance. In the genetic cross RrTt x RrTt, a number of ...
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Young family members to learn genetics - Amino Labs? [closed]

I'm an engineer but want to learn about biology with a niece and nephew who are early teens. I saw Amino Labs (https://amino.bio/) and thought because I work a lot with my hands, doing hands on ...
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2answers
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What is the chance a given gene will end up in a given gamete?

Let us say a somatic cell had a desired gene. This somatic cell was replicated during interphase so that it had two of the desired gene. It then underwent meiosis. My question then is, what is the ...
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2answers
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I'm not sure, are there 46 or 92 DNA strands in each somatic cell. Whatever, how many, then these strands join together to make a 6 or 7 ft long DNA?

When a cell is not divided it has DNA in chromatin form. Usually it is written in books that DNA is 6 ft long. In each cell there are 46 chromosomes, so there are 46 or 92 DNA strands. When a cell is ...
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Why is serum ferritin elevated in Chronic disease anemia?

I've been searching the reason of this but I've been not able to find it.
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1answer
43 views

Are there chromosomes that we inherit that are not recombinated? [closed]

We do have chromosomes that recombinated ,but aren't there pure chromosomes that are not recombinated that people would have?
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1answer
33 views

Can supplements affect DNA? (Could 10,000% Methylcobalamin affect MTHFR genotype)

Originally titled "Could B12 supplementation affect dna test results for B12 need?" - B12 just seems like a good example question to frame the more general question of "Can supplements affect DNA?" I ...
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1answer
39 views

Time taken for species to become endemic [closed]

Is it known how long species take to become endemic? I know from examples such as Canada which have no endemics following the end of glaciation that the process must take at least 10 thousand years, ...
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Measuring genetic distance: $F_{ST}$ vs. Nei's distance

As far as I'm aware, Nei's genetic distance is quite old compared to $F_{ST}$. However, I have recently read more papers that utilized Nei's genetic distance alongside with $F_{ST}$. As I'm not very ...
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1answer
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Fst genetic distance: Autosomal vs. mtDNA

As far as I'm aware, mtDNA is only inherited from the mother. Hence, if I compute Fst from autosomal SNPs, then I'll get the actual genetic distance between two human populations. If I compute the ...
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1answer
52 views

Its there a gene or genes for intelligence?

I don't know almost nothing of genetics but I felt a little interested in the subject of genetics and its role in intelligence and i found to reports that talk about certain genes that contribute to ...
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1answer
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Introgression vs admixture

What is the difference between genetic introgression and genetic admixture ? Are these terms interchangeable ? Do they apply to different population scopes or something ? The usage seems kind of vague ...
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1answer
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Why the SNPs from the earliest human haplogroups are missing in people outside of Africa if they are infact the descendants of it?

The SNPs M91, P97, M31, P82, M23, M114, P262, M32, M59, P289, P291, P102, M13, M171, M118 from haplogroup A and SNPs M60, M181, P90 from haplogroup B are missing in people without recent African ...
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2answers
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Can a viable embryo develop from the fusion of two egg cells?

For a zygote to form, two haploid gametes undergo meiosis and fuse during fertilisation. Since two egg cells (or even two sperm cells) are both haploid, is it theoretically possible for them to make ...
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1answer
96 views

Is marriage with half-cousin's daughter more risky than marriage with others?

I want to know is marriage with half-cousin's girl more risky than marriage with a non-family girl? Also I like to know if her parent are cousins(but from mother side), does it add more risk to this ...
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1answer
69 views

Could we back-breed birds into dinosaurs? [closed]

Do some species of birds have dinosaur DNA? Seeing as how birds evolved from dinosaurs. I presume this isn't possible as I haven't seen anything else about it on the internet but it's interesting to ...
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1answer
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How do the chromosomes arrange themselves after fertilization in humans?

In human reproduction the male produces sperm containing 23 chromosomes and the female has the oovum containing 23 chromosomes , so after fertilization the zygote contains 46 chromosomes. What I want ...
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1answer
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HLA typing between siblings to identify a genetic disorder

If a patient suffering from a complex array of signs and symptoms for a disease and is having an 8/8 loci match with his sister who suffers no such symptoms can you conclude that the disease is an X-...
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1answer
55 views

How to categorize non-coding sequences in the genome?

I'm trying to wrap my head around the diversity of functions in a genome. Obviously, you've got coding and non-coding regions. But within "non-coding" regions, it seems to be a "wild west" to me. ...
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1answer
39 views

Confusion about a gene's description

I have a very basic biology question. I am reading the description of gene FAM166A here, and I have no idea what "sequence similarity 166" means. What does 166 stand for, what is this gene's sequence "...
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True examples of common variation due to Mendelian Inheritance

Classic examples of mendelian inheritance are genetic diseases such as sickle-cell anemia, Tay-Sachs, cystic fibrosis, and xeroderma pigmentosa. For some of these diseases, it is believed that they ...
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1answer
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Neuroscience - A neuron with two types of synapses (electrical and chemical) at the same time

I learn that the nerves from the Peripheral Nervous System can carry signals from and to other organs of the body. I'm wondering if A Single Nerve carries 1) Only chemical signals 2) Only physical ...
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1answer
36 views

Mendelian dominant trait involved with Hypodontia [closed]

If the absence of teeth is a dominant trait, then why is it not seen in generations? My teacher taught that absence of teeth is a mendelian dominant trait, but why don't we see this trait if it is ...
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1answer
19 views

mRNA Sequencing Basepair from Polyadenylation Site?

I was wondering how many basepairs are usually sequenced with mRNA/cDNA illumina methods from upstream of the polyedenlation site? Thanks.
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Did the chromosomal fusion within humans affect phenotypical change compared to the separated chromosomes in the other apes?

I just read this article on the evolutionary divergence between humans and chimps, and how the most significant event was when the 24 number of chromosomes in chimps was reduced to 23 in humans due to ...
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2answers
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What happens to the complementary base when the other undergoes a base substitution mutation?

From what I know only the base pairs A and T/U, or G and C can occur due to hydrogen bonding. So if a base substitution mutation occurs, say an A is replaced by a C on the strand, does it affect only ...
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Estimating population divergence time with a single mitochondrial marker

Is it possible to estimate population divergence time with a single mitochondrial marker? Here is additional information for my specific case: Mitochondrial marker: Cytochrome Oxidase Subunit 1 (...
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1answer
19 views

Lac Operon and Arabinose Operon

In the lower concentration of glucose, what among lactose and arabinose, when both are present in the growth medium, is more likely to be utilized by E. coli?
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Gene flow analysis with a single mitochondrial marker

I am currently studying a mud snail genus called Ecrobia. Several species of this genus occur in both the Mediterranean and Black seas. Therefore, I would like to investigate whether there is: ...
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Is there any data to explore the heterozygosity of the South African lion over the last 18 years?

Background: I need to find data on the heterozygosity of the south African lion over the last 18 years... and I'm struggling: so far I have found a single data point. Question: Where can I find ...
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1answer
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What is the relationship between induction of cell differentiation and DNA methylation status?

This may sound like a broad question to ask, but I am working on interpreting a review article for my epigenetics course and I'm having trouble reconciling two seemingly contradictory things this ...
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Finding whether a DNA strand contains duplicate sequences

I know that using Hybridization Probes one can check if a nucleotide sequence complementary to the probe is present in a DNA strand by marking it and then verifying whether it attached the strand or ...
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2answers
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number of chromatids seen in karyotype

The karyotype is performed on a cell whose cycle has been stopped in metaphase or pro metaphase, using colchicine or by other means. In the textbooks I read that during the S phase each of the 46 ...