Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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2answers
43 views

Identify which of the two columns A and B represent gene and chromosome

I am a bit confused on this question in my Textbook (STD 12) and have got all sorts of answers on searching it but I am still not able to comprehend it literally. Can someone answer this and explain ...
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Systemic Sclerosis links?

What is the link between; vascular damage, Toll-Like Receptors and inflammation in systemic sclerosis?
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Do we actually know the Huntington chorea molecular mechanism?

I mean, did we know all genes involucrated on the dynamic mutation, and the protein that are used or it will be affected? I found this paper on chorea genetics from 2016 where literally concludes: ...
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31 views

Different types of DNA [on hold]

How B-DNA is converted to A-DNA in a less diluted solution? Please also explain the mechanism
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15 views

Why is sickle cell trait expressed in half of all cells rather than all cells containing half-sickled haemoglobin

If sickle cell trait is due to be heterozygous with respect to a single gene mutation on the haemoglobin β-globin chain, why is it the case that ~50% of RBCs are sickled rather than half of the ...
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2answers
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What is the advantage of circular DNA in bacteria?

From what I understand, bacteria have circular DNA. What advantages does it have over linear strands like for eukaryotes? Do there exist bacteria with more than one ring of DNA?
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Which trait does the given Pedigree chart show?

I have a doubt in this pedigree chart , according to me it should be autosomal dominant. But the ans given is X linked recessive , in the case of X linked recessive one daughter should be carrier and ...
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1answer
31 views

Is every flower on a plant unique?

I've noticed on my dahlia plants that sometimes there's a flower which looks completely different then the rest . Either color or structural. I dig these bulbs up each fall and keep inside to replant....
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How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share?

How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share? There are articles online that indicate that humans share xxx% of DNA with Chimpanzees, bananas, and other assorted ...
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Genetic equilibrium in case of two phenotypes and three alleles with inbreeding and fitness taken in account

Suppose there is an organism with diploid genome. Gen $A$ is represented with three possible alleles $A_1$, $A_2$ and $A_3$. Dominance is complete and the dominance hierarchy of alleles is following: $...
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2answers
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Do plants have distinctive DNA genomes from each other like humans do?

Can exact same species of plant have a distinct genome from others of same exact species growing nearby or in a different place/country etc. ? Can a leaf be traced to the the exact plant based on DNA ...
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1answer
80 views

What is the genetic reason that this flower has petals of two different colors?

I have two different varieties of the flower, portulaca: one is bright pink, the other is pure white with pink specks at the centre. Recently a flower bloomed which had 50% of the former and 50% of ...
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1answer
30 views

Do conservation oriented genetic database exist?

Are there any projects for the creation of the international genetic database of all endangered species, so we, at least, have a chance to clone them in the future if our current conservational ...
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1answer
147 views

Can primers for PCR be duplicated?

Complete beginner question here, don't laugh: If I have some primers that have been synthesized, and I am close to running out of them, is there any way to duplicate them / amplify them / synthesize ...
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2answers
1k views

Advantages of pain sensation?

The hazards of congenital insensitivity to pain (CIP) are well-known. This question is about the obverse: what selective advantage, if any, does the normal sensation of pain confer? I'm thinking of ...
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chromosome 19 and recombination

Im doing a project with structural variation created by recombination within the human genome during spermatogenesis, where im especially examining intrachromatid homolog recombination. I find that ...
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1answer
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Why does X inactivation happen?

Is X inactivation really important? Why don’t the dominant genes on one chromosome mask the recessive on the other chromosome? This happens in other sets of chromosomes so why exactly does this happen ...
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2answers
21 views

What's the difference between the terms “gene map” and “genome”?

It seems some sites arbitrarily restrict "gene map" to only a single chromosome, but others don't. Supposing we don't restrict it to just a single chromosome, is it different from "genome"? Are these ...
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Linkage terminology in drosophila

Consider two linked loci that are 50+ map units apart. I perform a test cross between a female that is heterozygous at both loci to a male that is homozygous recessive. In this case, the phenotypic ...
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Linker DNA and Genetic Expression

So I was reading on linker DNA, and the textbook only describes it in terms of structure. I was wondering if linker DNA can ever contain genes, and if it can, whether it will always be expressed or ...
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Inheritance percentiles

I am aware that the average DNA contribution from each grandparent is 25%, while the possible range is 0%-50%. I found a source citing 18%-32% as the "normal" range but this was undefined. I assume ...
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2answers
243 views

What was the biological mechanism that allowed Tarrare to eat so much?

Are there any conjectured mechanisms that cause Tarrare's extremely oversized stomach and abdominal cavity? Along with his superhuman appetite of course. Whether from a medical perspective or a ...
3
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1answer
82 views

Example of a virus becoming symbiotic with an organism

The human gut has an indispensably beneficial ecosystem of bacteria. What are the examples of a virus that becomes symbiotic with an organism, or even incorporates beneficially into the genome of the ...
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3answers
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Does recombination slow mutation accumulation in sexual populations? Is there any evidence?

Mullers Ratchet is the process by which asexual organisms would accumulate mutations without bound. It is claimed that sexual organisms would slow this mutation accumulation through recombination. Is ...
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Does intelligence depend more on environment than on genetic factors? [duplicate]

Many have argued that the test of IQ is simply a test of language. The application of the test consists of asking a number of questions. The person should understand the question presented to them and ...
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3answers
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Book Recommendations: GRE Subject Test In Biochemistry, Cell And Molecular Biology

There are probably a lot of really good answers that may vary significantly in terms of content. I'm looking for a set of books that I can read in preparation for the GRE Subject Test In Biochemistry,...
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1answer
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Chromosome naming convention: Why are there chromosomes named “1” and “1A”?

I've been stumbling on multiple genome of birds where there is a "1A" chromosome and a "1" chromosome. For example, the zebra finch has 1A and 4A. What does that mean? Do you have any resource about ...
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Is there any evidence that genes which are associated with physically adjacent structures are located near each other within the genome?

I am not sure if there are individual genes for, say, fingers and if so, would such genes be near the genes that affect hand growth? If not "near" in the Euclidean sense, could there be a different ...
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1answer
51 views

Balancing selection vs introgression?

Balancing selection can maintain polymorphisms in natural populations for extended periods of evolutionary time. However, in this paper, Dannemann et al. 2016 identify three archaic haplotypes in the ...
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2answers
177 views

Why would low complexity regions be linked with relaxed selection?

I'm reading a text (Wagner, 2007) on identifying positive selection. In the paper, the author says that low complexity regions are known to be associated with the relaxed selection. I'm trying to ...
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4answers
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Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

All humans have the same sort of proteins in our bodies. Take haemoglobin for example. Is the gene coding for haemoglobin in my body identical to everyone else's gene or is there slight variations ...
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4answers
107 views

Is variation a result of Evolution?

We know that the DNA copying mechanism that replicates DNA during cellular division is not 100% accurate and the resultant errors are the source of variation in the members of a population. At the ...
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1answer
52 views

The First Polymerase

Knowing that polymerase protein is needed for the transcription of genes, which polymerase is used in the transcription of polymerase protein itself?
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1answer
86 views

Fertilization of the human egg- where does our centrosome come from?

Is there a centrosome in a human egg cell? Is the reason why the egg cell remains paused before meiosis 2 because there isn't a centrosome, and it only divides when the sperm fertilizes it thus it can ...
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1answer
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When is it reasonable to assume selection for an observed change?

In speciation events, a lot of changes seems to appear simultaneously. How can a specific partial changes, occuring together with a lot of other changes, be said to be advantageous or disadvantageous? ...
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6answers
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Why these 2 dots frequently occur in dog's eyebrows? Do it serve/served any advantage?

It has been wonder me, in spite of so-many variations in color-patterns in dogs; these 2 dots (1 on each eyebrow) remains frequently occurring. Dog-1 Dog-1 close up. this one has a white dot. ...
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1answer
38 views

What does “genetic correlations” mean as opposed to just correlations?

I'm reading the paper "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior". In Fig. 4 shows "Genetic correlations of same-sex sexual behavior with various ...
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What is the average number of alleles per gene we have today?

Yesterday I was making some calculations, and I started to wonder the average number of alleles per gene the human species have today. The best question would be how many mutations per base or how ...
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1answer
52 views

x-linked recessive inheritance and correlation for males

I was inspired by a discussion in this thread. Wikipedia lists a number of disorders linked to recessive genes on the x-chromosome. One typical example is red-green color blindness. Now wikipedia says ...
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0answers
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Animal Transgensis - biological Implications?

I'm writing a report on the biological Implications of Transgensis of a cow which carried the gene for myelin sheath protein in its milk. I was wondering if anyone would know what sort of biological ...
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1answer
30 views

What is a Singleton Variant

I'm reading a paper that on a population genetics study where they sequence a number of genomes. The study states that 101 Singleton Variants per individual where found. What does Singleton mean?
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1answer
190 views

What is the expected amount of DNA shared by first cousins and the people between them in a family tree?

What is the expected amount of DNA that is shared by all of the people between first cousins, including the first cousins, in a family tree?
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How does chromosome doubling occur?

Sterile hybrid with genome AB undergoes doubling of chromosome set to form fertile tetraploid with genome AABB. But since A and B is not homologous, synapsis cannot occur at prophase I, so there is ...
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1answer
32 views

What percentage of Americans have Native Indian ancestry? [closed]

What percentage of americans have native indian ancestry? I tried to find the answer online and it's difficult to search for.
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2answers
5k views

Why do people with type O blood have anti-A and anti-B antibodies?

People with type O blood have anti-A and anti-B antibodies, even without receiving a transfusion. Why?
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1answer
46 views

Tools I can use to find similar genes

What tools are available to estimate the function and purpose of a gene ? I think the right approach is to find similar sequences of genes that we know the function of. All the information I have on ...
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3answers
129 views

Will modern-day insects grow to massive size in a high-oxygen environment?

It's a reasonably well-known fact that insects grew to massive sizes due to the excessive concentration of oxygen in the prehistoric-Earth's atmosphere. If one were to try to recreate this high-...
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2answers
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What could humans do to “see” what dogs smell?

We're able to see a lot of things using computers that we can't see normally: yellow-green, UV light, X-rays, etc. What do we have that harnesses the ability to "see" what dogs smell (e.g., harnessing ...
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2answers
1k views

Barr body Giemsa staining

Not all the female cheek cells show Barr Bodies when stained with Giemsa stain? Only 30 to 40% female cells show Barr Bodies. Why? Our Experiment: We washed mouth twice with listerine to reduce ...
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Why do I have 95% of chimpanzee's DNA, and only 2% of Neanderthal's DNA? [duplicate]

Excuse me if it is a question with a simply answer, but I don't understand these discoveries, looking a discrepancy from my unknowledge of genetics: I have 95% of Chimapanzee's DNA, and, I have [...