Stack Exchange Network

Stack Exchange network consists of 175 Q&A communities including Stack Overflow, the largest, most trusted online community for developers to learn, share their knowledge, and build their careers.

Visit Stack Exchange

Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

2
votes
2answers
81 views

Is DNA actually like source code repository?

So after reading articles like "People Use Just 8.2% of Their DNA" etc., and thinking a bit... I got this idea: What if DNA is actually like a software source code repository? You know, it has "...
4
votes
2answers
2k views

Are these cats calico?

Calico cats are cats that have 3 fur colors and are always female or males two X chromosomes. I've seen many cats that will have 2 fur colors (one of them is usually white) and another, third, color ...
0
votes
1answer
13 views
-2
votes
0answers
31 views

How many genes do viruses have? [on hold]

What is the range for the number of genes any virus contains? What is the average? Are there any viruses that contain only 1 gene?
1
vote
0answers
23 views

Absorbance anomaly

The standard concentration for absorbance of 1 for ssDNA is 33 ug/ml, while for RNA it is 40 ug/ml. I can't find the reason for the difference in this value for these two macro-molecules. My professor ...
0
votes
0answers
8 views

skin colouration in thalassemia

Now when i was studying about thalassemia, I read that anaemia is its major characterstic. I can understand that fact. But it was also written that the skin gets darker/pale. Wikipedia says that the ...
8
votes
1answer
656 views

Genetic expression in interspecific hybrids

Referring to interspecific hybrids, I have the following two questions:- Quoting from wikipedia:- The offspring of an interspecific cross are very often sterile; thus, hybrid sterility prevents ...
-3
votes
0answers
24 views

What does chrM stand for in a VCF file? [on hold]

I'm guessing the M is for Mitochondria, but Googling has not helped me to confirm this question. The wikipedia file for Variant Call Format also was not helpful.
0
votes
0answers
21 views

Intein Splicing

Currently I am trying to read and understand this paper on intein splicing. https://sci-hub.tw/https://www.ncbi.nlm.nih.gov/pubmed/22001202 However, I'm a little confused with Figure 4. Why do the ...
-1
votes
0answers
31 views

Why is the DNA structure a double helix? [on hold]

why DNA not mads any other linear structure other than double helix which thing responsible for DNA double helix.
0
votes
1answer
97 views

How to find which mutation in a protein is related to a disease? [on hold]

I have the FGFR3 protein in UniProt and they ask me to find which of the following four mutations is related to a disease: N98F, P64K, T79S, or F384L. Where can I find such information? Thanks
5
votes
2answers
589 views

Are all genes transcribed in differentiated cells?

My textbook tells me that it’s specific transcription factors that allow for a different set of genes to be expressed in different cells (differential gene expression). My book gives the example of ...
-1
votes
0answers
11 views

What is the meaning of child additive to dominance effect, dc/ac =0.5?

I am conducting collaborative research about family-based genome-wide association study, where I am using the genotypes data. There is a point called "child additive to dominance effect, dc/ac =0.5", ...
0
votes
0answers
20 views

Control of protein by DNA sequence with respect to RNA polymerase

I want to know how can a particular base sequence like the TATA box in the -10 region of a gene is able to regulate a protein's function like RNA polymerase? What kind of interaction really occurs?Is ...
8
votes
3answers
759 views

How close genetically is the most human-like chimpanzee to the most chimp-like human?

I understand that: Chimpanzees are the closest species to humans genetically. Only 1%-6% of their genes are different. Within any species there is genetic diversity, i.e. no two individuals have the ...
-1
votes
0answers
21 views

this is a question regarding distance between genes,how is this question done? [closed]

[![this is a question regarding distance between genes,how is this question done?][1]][1] [1]: https://i.stack.imgur.com/1xtF1.jpgthis is a question regarding distance between genes,how is this ...
0
votes
1answer
77 views

In what does Genetic clustering and Cline sharpness differ?

They are both ways to measure divergence in species but I'm not understanding in what exactly the differ if both use hybrid zones and gene frequencies in the study.
2
votes
2answers
290 views

number of chromatids seen in karyotype

The karyotype is performed on a cell whose cycle has been stopped in metaphase or pro metaphase, using colchicine or by other means. In the textbooks I read that during the S phase each of the 46 ...
-2
votes
1answer
33 views

What is the gene for height?

Height doesn't seem to be linked to sex, which is surprising. I have seen ways to predict children's height and it involves taking the average of both parents height. Upon my search, I did not find ...
1
vote
2answers
2k views

Genes & Map Units

Two genes of a flower, one controlling blue (B) versus white (b) petals and the other controlling round (R) versus oval (r) stamens, are linked and are 10 map units apart. You cross a homozygous blue ...
3
votes
1answer
77 views

Webtool to design guide RNA (gRNA) for use with CRISPR-AsCpf1?

My goals are to use a free webtool to: Identify guide RNAs (direct-repeat sequence followed by the targeting sequence) appropriate for use with AsCpf1 in order to target a specific segment of genomic ...
0
votes
1answer
24 views

x-linked recessive inheritance and correlation for males

I was inspired by a discussion in this thread. Wikipedia lists a number of disorders linked to recessive genes on the x-chromosome. One typical example is red-green color blindness. Now wikipedia says ...
1
vote
1answer
38 views

How to download different kinds of data from NCBI eutils?

I have been researching NCBI eutils and wish to get some 'big data' from it. I know that I can construct queries to query one of (I think) 8 databases, like this: ...
2
votes
4answers
87 views

What's the benefit of the average human body temperature?

Why would the body choose a resting temperature of 36.1c to 37.2c? It seems a very inefficient mechanism of survival considering the typical ambient temperatures on Earth. If there is a benefit to ...
4
votes
3answers
273 views

Have humans finished evolving?

I thought that massive changes among organisms are over long periods of time. This is caused by, to my knowledge: Evolutionary pressure Natural/artificial selection Mutations Genetic drift Will ...
-1
votes
0answers
21 views

What is the difference between different schools of taxonomy?

I have been quite interested about biology lately. I would like to know what are some of the main differences between schools of taxonomy. Thank you for the answer!
0
votes
1answer
10 views

Maximum recombination frequency [duplicate]

During the process of crossing over, Why is the maximum possible recombination frequency between two genes equal to 50% and not more than that?
1
vote
0answers
73 views

The space of all human DNAs [closed]

This is both a math and biology question but I think it makes more sense for a biologist to answer it. My question is: what can be said, if anything, about the space of all possible human DNAs (for a ...
1
vote
1answer
20 views

If DNA methylation inactivates genes, does DNA demethylation activate them?

DNA demethylation can be passive or active. The passive process takes place in the absence of methylation of newly synthesized DNA strands by DNMT1 during several replication rounds – for example, ...
10
votes
3answers
30k views

What's the difference between shotgun sequencing and clone based sequencing?

In a lecture during my undergraduate degree we were introduced to the race to complete the human genome. Celera were competing with Sanger and collaborators to sequence the human genome. Celera ...
5
votes
3answers
741 views

What is the difference between silent and synonymous mutations?

Several sources all caution that silent mutations and synonymous substitutions are not the same thing and should not be confused. But they seem to draw different actual distinctions between the terms: ...
2
votes
2answers
781 views

Why can't this be 1st meiotic division non-disjunction as well?

The child has gotten 2 "sick" chromosomes from his dad and 1 healthy from his mom, leaving it with trisomy 13. I can see how this can happen in the second meiotic division of the father but I can ...
10
votes
4answers
8k views

Is Chargaff's rule really applicable?

Chargaff's rules states that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to ...
-4
votes
3answers
4k views

Did cats evolve from monkeys ? or vice versa?

Did cats evolve from monkeys? or vice versa? How similar are the genes of cats and monkeys? What is the proof that they are related or that they are not related? Most monkeys climb in trees and ...
0
votes
0answers
24 views

Is Wikipedia a good source of taxonomy? [duplicate]

I have been quite interested in biology lately,and I would like to know whether it is a good choice to look up taxonomic information there.
17
votes
2answers
3k views

What is the smallest number of amino acids required for life?

Is there any hypothesis on the minimum number of amino acids required for life?
15
votes
2answers
11k views

Genetic linkage greater than 50 centimorgans

Classically, the linkage between two loci can be measured in centimorgans (cM), which represents the percent chance that these two loci will recombine an odd number of times (generating a recombinant ...
0
votes
1answer
27 views

Possible combinations in the Meiosis' Telophase 1

As you might already know Meiosis is the process in eukaryotic, sexually-reproducing animals that reduces the number of chromosomes in a cell before reproduction $^{[1]}$ One of the reasons why ...
12
votes
1answer
758 views

Why does size decrease across the sequence of human chromosomes?

The following graph shows a decrease in the number of base pairs per chromosome across the sequential set of human chromosomes: Is this because chromosomes were originally numbered by their size on ...
11
votes
1answer
252 views

How can the number of genes increase through evolution?

I am aware of the basics of evolutionary theory, however I don't understand how mutations can add genes over time. Am I correct in thinking that creatures within the same species who mutate to have ...
7
votes
2answers
2k views

Why is the strength of genetic drift inversely proportional to the population size?

I saw a concept on the Internet that says "the strength of genetic drift is inversely proportional to the population size". I don't know why they are inversely proportional? Can somebody explain? ...
-1
votes
0answers
28 views

E. coli (K-12) sample is not dying to isopropyl alcohol

I am doing a high school science project on the effectiveness of household antiseptics and the resistances the bacteria evolve to them. I am using E. coli K-12. In the sample, the bacteria population ...
7
votes
2answers
2k views

What is the instructional language of DNA?

DNA carries most of the genetic instructions used in the development, functioning and reproduction of all known living organisms and many viruses (Wikipedia). Is it already know how ATCG's sequences ...
14
votes
3answers
2k views

Can genes change as we age?

Let's say you're a 23-year-old man who impregnates a woman. Will your genes be the same if you were to impregnate another woman at age 35? Will your genes in those 12 years have changed/mutated/become ...
6
votes
5answers
4k views

Why do most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: From changing environments. Mutations. Possibly even genetic ...
12
votes
2answers
18k views

Does one parent transmit more DNA to the offspring than the other one?

Does one parent transmit more DNA to the offspring than the other one? Or do both parents always transmit the same amount of genetic material to their offspring? In other words, can a baby be ...
23
votes
4answers
3k views

Why is a heritability coefficient not an index of how “genetic” something is?

On his blog, Eric Turkheimer writes: [T]aken as a number, a unit of analysis, heritability coefficients are funny things to aggregate on such a massive level. What exactly are we supposed to ...
11
votes
5answers
3k views

How does DNA still work after recombination?

If you take two computer programs and randomly swapped pieces from each of them. The result is not going to work. It will just be garbage. If you take two novels and randomly swapped chapters the ...
54
votes
4answers
6k views

Why do men have nipples?

I'd be tempted to call nipples in men vestigial, but that suggests they have no modern function. They do have a function, of course, but only in women. So why do men (and all male mammals) have them?
2
votes
1answer
75 views

How much of my ancestry will match with my brother?

Recently, my brother (full sibling) got his ancestry checked from MyHeritageDNA. They have a similar service like 23 and me and I've found out that both companies are offering the basic service almost ...