Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

Filter by
Sorted by
Tagged with
0
votes
1answer
2k views

Is brachydactyly due to mutation?

I have this so called "clubbed thumbs"also known as brachydactyly. It is of D-type. I searched for it on internet and found that it is a dominant inherited disease. But to my surprise,none of my ...
6
votes
3answers
812 views

Is the genetic term “polycistronic” still used in modern biology?

Is the term "cistronic", meaning an ORF on a mRNA, still commonly used in modern genetics? I´ve seen "polycistronic" being applied to prokaryotic mRNA in old textbooks, but I´ve rarely stumbled upon ...
0
votes
0answers
46 views

Inbreeding depression in Gouldian Finches

I currently breed Gouldian finches, including the yellow mutation. I was lucky to breed 6 youngsters including pure yellow and yellow split. How far can I interbreed the offspring (i.e step brothers/...
1
vote
0answers
22 views

Species diversity in cheese and yoghurt?

There have been studies on the number of species on humans and in various other environments. I was wondering how many species including: viruses, bacteria, yeasts, and fungi inhabit ordinary farm ...
-1
votes
1answer
43 views

Confusion about result of monohybrid cross in Mendelian genetics

I was studying monohybrid crosses in genetics where the character considered is stem height. Whenever I came across punnett squares, I used to calculate the probability of the genotype of the ...
4
votes
3answers
156 views

What makes an E.coli an E.coli, genotype or phenotype?

According to this paper, among 61 strains of E. coli they studied only 6% of the genes are common in all. Which means that the overwhelming majority of the genes are not shared. And wikipedia ...
0
votes
1answer
70 views

If coelocanths are more related to humans than groupers -does a Coelocanth's DNA literally have more sequences in common with a human than a grouper?

Would a coelocanth and a human still have more sequences in common than a coelocanth and a grouper? Would the coelocanth and human dna basically "look" more similar than either would to a ray-finned ...
1
vote
2answers
108 views

In marine DNA viral diversity studies, what would “paradigm of rampant mosaicism” refer to?

The recent paper in Cell Marine DNA Viral Macro- and Microdiversity from Pole to Pole describes the (huge) new Global Ocean Viromes 2.0 (GOV 2.0) dataset. In the Results and Discussion section, the ...
2
votes
1answer
125 views

What's the exact meaning of and how to derive the coefficient of the path from sire to offspring?

According to Wright's Coefficients of Inbreeding and Relationship, the coefficient of the path from sire to offspring is given as $p_{o \cdot s}=\frac{1}{2}\frac{\sqrt{1+F_s}}{\sqrt{1+F_o}}$ But ...
0
votes
1answer
50 views

What is the use of having a surrogate mother in animal cloning?

In animal cloning, an ovum is collected by an animal and processed to form an embryo after fusion, which is going to be inserted to a surrogate mother. So my question is that why can't the embryo be ...
0
votes
1answer
20 views

Easy Hardy Weinberg Equilibrium [duplicate]

Hi My friend and I get 2 different answers to this question. I would like to know how to calculate the value of q. My friend says that 500/1500=q because there are 500 recessive alleles in the ...
0
votes
1answer
38 views

Studying the epigenetic variability, can I use SNPs?

So, I'm trying to study the effects of epigenetic variability on the brain structure. Can I use SNPs associated with a gene's higher expression to compute the likelihood of that gene being expressed ...
0
votes
1answer
89 views

Are all fusion genes somatic in origin or can fusion genes be germline?

Fusion genes should have an origin.These are essentially hybrid genes that are translocated in its entirety. Eg. BCR-ABL, EML4-ALK are known to be implicated in cancer pathogenesis. Do these ...
1
vote
2answers
3k views

What is Mendelian Segregation and how is it related to the Hardy-Weinberg equilibrium?

I can't find the exact definition of Mendelian segregation. In addition, I am wondering how it is related to the Hardy-Weinberg equilibrium?
1
vote
1answer
33 views

Are chromosomal microdeletions passed on?

I've been looking around but can't find a clear answer: are chromosomal micro-deletions passed on (hereditary) or not?
1
vote
1answer
64 views

What does “PDPN+ cells” means?

Are they podoplanin positive cells (cells that tested positive for podoplanin)? "...though it has been shown that podoplanin (PDPN+) cells analogous to mouse FRCs are found in human secondary ...
2
votes
2answers
138 views

Rationale behind Most Recent Common Ancestor (MRCA)?

My main question is this - I heard Richard Dawkins say in a video that after 1000s of years, any given individual alive today will be either an ancestor to ALL of the humans (in that future time) or ...
0
votes
1answer
39 views

How to search for a DNA sequence in a genome on ENA (European Nucleotide Archive)?

I have to do a search for small DNA sequences in the genome of an organism in ENA. I have the accession number and project id. However, I can't download the whole genome because of the download size ...
5
votes
1answer
231 views

How can a child be blood type AB, if both of the parents are blood type A?

Basically, both of my parents are blood type A (both are confirmed and it's also certain both of them are my biological parents). I recently found out my blood type is AB. How is this possible? I ...
2
votes
0answers
44 views

What the “due to” means in the definition of heritability?

According to Wray and Visscher, heritability is formally defined as the proportion of phenotypic variation (VP) that is due to variation in genetic values (VG). My question is, what does “due to” ...
3
votes
4answers
12k views

Are gametes diploid or haploid?

Some sources say that gametes are haploid, some say that they are diploid. I'm confused.
0
votes
0answers
20 views

For eQTL analysis, is it ok to combine all the ethnic groups?

I am performing eQTL analysis, and wish to be answered for a quick question. In conducting eQTL analysis, biologically, is it fine to include subjects from all ethnic groups (to increase statistical ...
3
votes
3answers
324 views

What does the gene name “lexA” stand for?

It is an important gene expressed in E. coli that represses the SOS response and also the expression of lambda lytic phase genes. UV light and damage to DNA is responsible for its breakdown and hence ...
3
votes
1answer
422 views

Left and Right Handedness

Today I found out that the gene for being Left-handed is dominant while Right-handed is recessive. I personally am left handed and so is my father. My mothers father is also left handed and I was ...
0
votes
0answers
89 views

Number of DNA strands per chromosome

As I was reading Griffith's Introduction to genetic analysis this evidence was provided for single DNA makes single chromosome. Eventually geneticists demonstrated directly that certain chromosomes ...
0
votes
1answer
46 views

What species would this be?

A common way to define species can be found on Wikipedia: A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can ...
0
votes
1answer
45 views

Gene frequency — database/site

Is there any free database when one can check the gene frequency in a healthy population? For example I would like to check it for genes like BIN1, CLU or CR1. On the English Wikipedia I found a gene ...
2
votes
1answer
46 views

skin colouration in thalassemia

Now when i was studying about thalassemia, I read that anaemia is its major characterstic. I can understand that fact. But it was also written that the skin gets pale. Wikipedia says that the skin ...
1
vote
2answers
58 views

Meaning of letter “c” in description of mutation: “Homozygous c.195C>G; (p.Cys65Trp)”

In a table in a paper titled Cerebral folate deficiency: Analytical tests and differential diagnosis, there's the following description of a mutation in a patient: Homozygous c.195C>G; (p.Cys65Trp)...
-1
votes
1answer
91 views

Is it possible to change the DNA of all the cells of an adult human [closed]

The process of making and transferring changes is pretty straightforward relatively speaking in an embroyo. You change the DNA of one cell and all the cells now inherit this change. But let's say ...
4
votes
0answers
86 views

Mechanism behind Philadelphia chromosome translocation?

I was reading up on causative factors of leukemia on medicinenet and I came across the following statement: ...an exchange between chromosomes 9 and 22 leads to what is known as the Philadelphia ...
1
vote
1answer
88 views

If some humans inherited 3% of Neanderthal DNA, why are we 99.9% same genome? [duplicate]

Many sources say that humans are 99.5 to 99.9 percent the same. Also some sources state that some humans have 3.4% Neanderthal DNA and some don't share those genes. Why is that?
4
votes
2answers
730 views

Are all genes transcribed in differentiated cells?

My textbook tells me that it’s specific transcription factors that allow for a different set of genes to be expressed in different cells (differential gene expression). My book gives the example of ...
0
votes
0answers
29 views

Why can't a genetically sound human stay alive for an indefinite amount of time given all the ideal conditions? [duplicate]

I have read that even if we can control our food and lifestyle and keep things as ideal as possible, there are other factors beyond our control like effects from neutrinos passing through our body ...
1
vote
1answer
33 views

How are haplotype blocks different from genes?

According to Cardon et al. 2003, a haplotype block is A discrete chromosome region of high linkage disequilibrium and low haplotype diversity. It is expected that all pairs of polymorphisms ...
0
votes
1answer
41 views

Do human genes get affected by irregular sleep and other factors

I'm new here so please go easy on me. Do our genes-the ones that carry our appearance, intelligence and other traits get destroyed or lost due to irregular sleep, excessive body heat, smoking, ...
7
votes
2answers
2k views

Why is the strength of genetic drift inversely proportional to the population size?

I saw a concept on the Internet that says "the strength of genetic drift is inversely proportional to the population size". I don't know why they are inversely proportional? Can somebody explain? ...
2
votes
0answers
50 views

Recombination due to crossover, outcome?

Garden peas normally have 7 pairs of chromosomes (n=7, 2n=14). Please calculate how many different types of gametes can be produced through the meiotic process if no crossover happens. If cross-over ...
1
vote
0answers
24 views

Is it possible to Clone a Dinosaur with a full strand of their DNA? [duplicate]

If you have a full strand of Dinosaur DNA would it be possible to make it living and hatch a dinosaur? Or would it be a failure? Could you use a bird or alligator, for replacein
0
votes
1answer
58 views

Where can I find DNA decryption research? [closed]

What is the name of the science that studies the mathematics of DNA? Where can I learn about maths, statistics, types of code, numbers, patterns and graphs for genes and information found in DNA?
0
votes
2answers
57 views

What's the difference between reaction norms and phenotypic plasticity?

I'm trying to understand better these two concepts, but I cannot see a clear difference yet. Reaction norm: "set of phenotypes that can be produced by an individual genotype when exposed to different ...
1
vote
0answers
13 views

How does a neutral allele change relative to a nearby allele under selection?

Suppose I'm looking at a gene being selected against (A) that's decreasing at a rate ($\Delta$P). If there's a nearby allele that is neutral (B) am I correct to assume that B will decrease with A at a ...
2
votes
1answer
2k views

Are left-handed people more likely to be colorblind?

My friend, uncle, and I are left handed and also suffer from Protan colorblindness. Is it more likely for left-handed people to be colorblind? Disclaimer: I was originally Right handed and due to a ...
1
vote
2answers
30 views

Is there natural occurrence of induced pluripotency / expression of Yamanaka factors and what is the evolutionary explanation of that?

Is there natural biological processes in which the full (full reprogramming into pluripotent state) or partial (partial reprogramming, stopped before point-of-no-return, preserving the functional ...
-1
votes
1answer
45 views

Can Females Songbirds Have Male Plumage?

Male birds are colorful for courtship displays, females are dull for camouflage. But, is written in a website somewhere that sometimes, when females birds are sterile, they grow male plumage due to ...
-2
votes
1answer
43 views

is it possible for a son to inherit an allele on a Y chromosome?

Obviously, the only way for one to be male is to inherit the Y chromosome, but are there alleles on the y chromosomes? Or is it just automatically the recessive trait without an allele.
0
votes
0answers
25 views

N value in a GWAS?

Just like the title says. I am reading about a GWAS but I don't know much about them. I understood most of it but I couldn't figure out what the "n" value was.
6
votes
3answers
3k views

Math behind the Genetic Relationship Matrix

The genetic relationship matrix (GRM) can estimate the genetic relationship between two individuals ($j$ and $k$) over $m$ SNPs and $i$ representing a specific SNP. What I don't understand from their ...
2
votes
0answers
17 views

Need help to determine % difference between DNA-strand from two different haplotypes. Known nucleotide diversity and more

Backround: 229 DNA sequences 493 bp in length Haplotype diversity: 0.9956 Average number of nucleotide differences: 12.50544 Polymorphic sites: 145 Nucleotide diversity: 0.02426 Is it possible ...
1
vote
1answer
42 views

If DNA methylation inactivates genes, does DNA demethylation activate them?

DNA demethylation can be passive or active. The passive process takes place in the absence of methylation of newly synthesized DNA strands by DNMT1 during several replication rounds – for example, ...

1
3 4
5
6 7
42