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Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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What are the differences in the two possible methods to calculate the Hardy-Weinberg Equation?

I am more than flabbergasted by calculations of Hardy-Weinberg equilibria. The formula's theory assumes a binomal distribution of allele frequencies in a population, and hence allows the comparison of ...
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why and how multi allele gets reported during variant calling in vcf?

This might be a very basic question for many here. With the basic understanding of inheritance, eventhough there is a possibility of multiple genotypes due to multi alleles, the resulting genotype can ...
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1answer
121 views

Do chromosomes line up as pairs in mitosis or meiosis?

Here is a question from the book SAT II Success Biology E/M (where the SAT is the exam taken by the American high school students): Homologous chromosomes line up in pairs in (A) metaphase of ...
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1answer
67 views

Is it theoretically possible to safely eliminate most viruses in the atmosphere, hence preemptively cure all the viral diseases? [closed]

Could we create a genetically modified virus or bacteria (with inability to mutate into something dangerous for animals) that would quickly spread all over the planet and selectively kill most of the ...
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1answer
72 views

On which chromosomes were the traits studied by Mendel?

In his experiment with peas, Mendel mainly studied two traits : yellow/green colours and round/wrinkly shapes. I've heard that the pea genome is very large and its sequencing is a challenge. However, ...
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1answer
46 views

Basic questions about human genome project [closed]

The "human genome" was sequenced by the Human Genome Project around 2000. But I don't understand what was done and what its significance is. Questions: Wasn't a single person's genome sequenced? I....
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1answer
474 views

Is there logic in this sentence? “Authors discovered a gene as one of the genes evolved through natural selection”

From a news report: PhD candidate Daiki Sato and Professor Masakado Kawata have discovered SLC18A1 (VMAT1), which encodes vesicular monoamine transporter 1, as one of the genes evolved through ...
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1answer
66 views

What is the meaning of Sequestered germline?

What is the meaning of Sequestered germline. I understand the meaning of Sequestered in English but what is its meaning in context of germline. For eg-" female germ cells are Sequestered early in ...
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1answer
60 views

Does a reproductively successful male have the same genetics as a reproductively successful female?

Evolutionarily, using humans as an example, it would make sense that a successful female would produce successful male offspring. If a successful female produced male offspring that weren't successful,...
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1answer
48 views

Non-coding DNA correlation with rate of evolution

Non-coding DNA can be helpful in generating useful mutations that can go on to become new features/functionality of an organism. Non-coding DNA also indirectly reduces chances of mutation of useful/...
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1answer
204 views

are clones siblings to the original?

i have a question about cloning, if a person had his/her DNA sample like hair or blood used to make a clone wouldn't that clone be that same person's brother or sister since they share the same ...
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1answer
102 views

Is the mutation rate in pseudogenes higher than in coding regions?

Coding genes are subject selective pressure that are not present for pseudogenes, that would suggest that pseudogenes have a higher mutation rate than coding regions. If so, how much higher?
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Could the Immune Gene HLA-B27 be gentically altered, snipped, switched off, replaced, edited within the body

Could the Immune Gene HLA-B27 be genetically altered, snipped, switched off, replaced, edited within the body.? Thousands upon thousands suffer immune disease as do I from this highly implicated gene....
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1answer
232 views

Dihybrid cross question

An experiment is set up to study two genes. The two genes assort independently and for each gene the expression of alleles involves complete dominance. In the genetic cross RrTt x RrTt, a number of ...
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Young family members to learn genetics - Amino Labs? [closed]

I'm an engineer but want to learn about biology with a niece and nephew who are early teens. I saw Amino Labs (https://amino.bio/) and thought because I work a lot with my hands, doing hands on ...
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2answers
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What is the chance a given gene will end up in a given gamete?

Let us say a somatic cell had a desired gene. This somatic cell was replicated during interphase so that it had two of the desired gene. It then underwent meiosis. My question then is, what is the ...
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2answers
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I'm not sure, are there 46 or 92 DNA strands in each somatic cell. Whatever, how many, then these strands join together to make a 6 or 7 ft long DNA?

When a cell is not divided it has DNA in chromatin form. Usually it is written in books that DNA is 6 ft long. In each cell there are 46 chromosomes, so there are 46 or 92 DNA strands. When a cell is ...
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1answer
52 views

Are there chromosomes that we inherit that are not recombinated? [closed]

We do have chromosomes that recombinated ,but aren't there pure chromosomes that are not recombinated that people would have?
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1answer
45 views

Can supplements affect DNA? (Could 10,000% Methylcobalamin affect MTHFR genotype)

Originally titled "Could B12 supplementation affect dna test results for B12 need?" - B12 just seems like a good example question to frame the more general question of "Can supplements affect DNA?" I ...
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1answer
44 views

Time taken for species to become endemic [closed]

Is it known how long species take to become endemic? I know from examples such as Canada which have no endemics following the end of glaciation that the process must take at least 10 thousand years, ...
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Measuring genetic distance: $F_{ST}$ vs. Nei's distance

As far as I'm aware, Nei's genetic distance is quite old compared to $F_{ST}$. However, I have recently read more papers that utilized Nei's genetic distance alongside with $F_{ST}$. As I'm not very ...
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1answer
37 views

Fst genetic distance: Autosomal vs. mtDNA

As far as I'm aware, mtDNA is only inherited from the mother. Hence, if I compute Fst from autosomal SNPs, then I'll get the actual genetic distance between two human populations. If I compute the ...
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1answer
83 views

Its there a gene or genes for intelligence?

I don't know almost nothing of genetics but I felt a little interested in the subject of genetics and its role in intelligence and i found to reports that talk about certain genes that contribute to ...
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1answer
226 views

Introgression vs admixture

What is the difference between genetic introgression and genetic admixture ? Are these terms interchangeable ? Do they apply to different population scopes or something ? The usage seems kind of vague ...
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2answers
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Why the SNPs from the earliest human haplogroups are missing in people outside of Africa if they are infact the descendants of it?

The SNPs M91, P97, M31, P82, M23, M114, P262, M32, M59, P289, P291, P102, M13, M171, M118 from haplogroup A and SNPs M60, M181, P90 from haplogroup B are missing in people without recent African ...
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2answers
158 views

Can a viable embryo develop from the fusion of two egg cells?

For a zygote to form, two haploid gametes undergo meiosis and fuse during fertilisation. Since two egg cells (or even two sperm cells) are both haploid, is it theoretically possible for them to make ...
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1answer
135 views

Is marriage with half-cousin's daughter more risky than marriage with others?

I want to know is marriage with half-cousin's girl more risky than marriage with a non-family girl? Also I like to know if her parent are cousins(but from mother side), does it add more risk to this ...
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1answer
97 views

Could we back-breed birds into dinosaurs? [closed]

Do some species of birds have dinosaur DNA? Seeing as how birds evolved from dinosaurs. I presume this isn't possible as I haven't seen anything else about it on the internet but it's interesting to ...
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1answer
70 views

How do the chromosomes arrange themselves after fertilization in humans?

In human reproduction the male produces sperm containing 23 chromosomes and the female has the oovum containing 23 chromosomes , so after fertilization the zygote contains 46 chromosomes. What I want ...
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1answer
21 views

HLA typing between siblings to identify a genetic disorder

If a patient suffering from a complex array of signs and symptoms for a disease and is having an 8/8 loci match with his sister who suffers no such symptoms can you conclude that the disease is an X-...
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1answer
79 views

How to categorize non-coding sequences in the genome?

I'm trying to wrap my head around the diversity of functions in a genome. Obviously, you've got coding and non-coding regions. But within "non-coding" regions, it seems to be a "wild west" to me. ...
2
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1answer
42 views

Confusion about a gene's description

I have a very basic biology question. I am reading the description of gene FAM166A here, and I have no idea what "sequence similarity 166" means. What does 166 stand for, what is this gene's sequence "...
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True examples of common variation due to Mendelian Inheritance

Classic examples of mendelian inheritance are genetic diseases such as sickle-cell anemia, Tay-Sachs, cystic fibrosis, and xeroderma pigmentosa. For some of these diseases, it is believed that they ...
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Neuroscience - A neuron with two types of synapses (electrical and chemical) at the same time

I learn that the nerves from the Peripheral Nervous System can carry signals from and to other organs of the body. I'm wondering if A Single Nerve carries 1) Only chemical signals 2) Only physical ...
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1answer
38 views

Mendelian dominant trait involved with Hypodontia [closed]

If the absence of teeth is a dominant trait, then why is it not seen in generations? My teacher taught that absence of teeth is a mendelian dominant trait, but why don't we see this trait if it is ...
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1answer
20 views

mRNA Sequencing Basepair from Polyadenylation Site?

I was wondering how many basepairs are usually sequenced with mRNA/cDNA illumina methods from upstream of the polyedenlation site? Thanks.
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Did the chromosomal fusion within humans affect phenotypical change compared to the separated chromosomes in the other apes?

I just read this article on the evolutionary divergence between humans and chimps, and how the most significant event was when the 24 number of chromosomes in chimps was reduced to 23 in humans due to ...
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2answers
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What happens to the complementary base when the other undergoes a base substitution mutation?

From what I know only the base pairs A and T/U, or G and C can occur due to hydrogen bonding. So if a base substitution mutation occurs, say an A is replaced by a C on the strand, does it affect only ...
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0answers
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Estimating population divergence time with a single mitochondrial marker

Is it possible to estimate population divergence time with a single mitochondrial marker? Here is additional information for my specific case: Mitochondrial marker: Cytochrome Oxidase Subunit 1 (...
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1answer
24 views

Lac Operon and Arabinose Operon

In the lower concentration of glucose, what among lactose and arabinose, when both are present in the growth medium, is more likely to be utilized by E. coli?
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Gene flow analysis with a single mitochondrial marker

I am currently studying a mud snail genus called Ecrobia. Several species of this genus occur in both the Mediterranean and Black seas. Therefore, I would like to investigate whether there is: ...
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Is there any data to explore the heterozygosity of the South African lion over the last 18 years?

Background: I need to find data on the heterozygosity of the south African lion over the last 18 years... and I'm struggling: so far I have found a single data point. Question: Where can I find ...
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1answer
54 views

What is the relationship between induction of cell differentiation and DNA methylation status?

This may sound like a broad question to ask, but I am working on interpreting a review article for my epigenetics course and I'm having trouble reconciling two seemingly contradictory things this ...
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Finding whether a DNA strand contains duplicate sequences

I know that using Hybridization Probes one can check if a nucleotide sequence complementary to the probe is present in a DNA strand by marking it and then verifying whether it attached the strand or ...
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2answers
161 views

number of chromatids seen in karyotype

The karyotype is performed on a cell whose cycle has been stopped in metaphase or pro metaphase, using colchicine or by other means. In the textbooks I read that during the S phase each of the 46 ...
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Increasing my PCR efficiency to be able to better visualise my bands

I run an electrophoresis in agarose gel and my expected bands are extremely week, is even hard to see them. It looks I need to increase my PCR efficiency. I have read about a Hot start setp, which ...
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1answer
60 views

What exactly happens during the crossover [closed]

My knowledge of biology is rather limited, but I think I have a grasp of some basic concepts. For me (as a person close to math) a chromosome is a sequence of elements from the set {A,C,T,G} of some (...
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Is Rh factor an evidence for human evolution from primates?

The Rhesus Factor is an important blood antigen that is found on Rhesus macaque and human being. So is this an evidence for human evolution from monkeys. ???
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Genetics and evolution: Cross between plant

Three corn phenotypes plant-color booster, liguleless and silkless are all controlled by a single gene located on the same chromosome. In all cases, the wild type allele is dominant. A cross between a ...
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How are animal patterns encoded in the dna?

After seeing the patterns on the feathers of a argusianus argus pheasant (shown below), I am curious where is the information that encodes a pattern for a particular bird, and what form is this ...