Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Recombination Data Set

So I was looking over some genetics question and came across this data set. In Fruit fly Drosophila melanogaster, there is a dominant gene b+ for grey body color and another dominant gene c+ for ...
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Why doesn't complete melanism exist in humans? [duplicate]

What would be the evolutionary reasons? Is it because of the importance of vitamin D?
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How can individual strands of coat hair have only a single color when considering codominance?

I understand how codominance works. We have two (or more) alleles for one gene, neither having dominance over the other. They are both expressed independently, which means that different phenotypes ...
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Pedigrees - Autosomal Dominant vs Recessive Question

I saw this question and the answer key says that the pedigree shows autosomal dominant inheritance. But I'm a bit confused because can't it show autosomal recessive inheritance as well?
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Edit: P generation: AAbbddEEff X aaBBDDeeFF. If A and B are 40 centimorgan apart, what is the probabilty to get aabbddeeff in F2?

(F1 is: AaBbDdEeFf. Then, it goes through this: AaBbDdEeFf X AaBbDdEeFf). I drew the 2 chromosomes for AaBb (in coupling) and then: the possibilty for a is 0.5 (A or a) and the possibilty for no ...
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DNA mutations in humans are generally bad, but why in viruses make their bodies stronger?

I want to know why this happens to viruses. can we apply that technique to the human body too
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Evolution: Can the genotype frequencies change, but the allele frequencies remain constant?

If a population isn't evolving because it's in Hardy-Weinberg (HW) equilibrium, then I know that both genotype and allele frequencies must stay constant. My question is, can evolution still not occur ...
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When is it better for a gene to cause a biased sex ratio?

Because genes are selfish and want to maximise their transmission from generation to generation, if they can distort a population's sex ratio, isn't it always in their interest to cause a biased sex ...
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Using punnett squares to express sex/gene linkage and recombination frequency

I have been using punnett squares to visualize mating experiments. I am looking at a pairing which is known to have a crossover event occur. I know from empirically collected data the recombination ...
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What are the effect of radioactivity on grey wolves in Chernobyl?

I am doing some research about the effects that radioactivity has and is having on grey wolves in Chernobyl and more particularly on their genetics, but maybe also looking at the populations in the ...
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Why are adenoviral vector vaccines safe in terms of insertion mutagenesis due to genome integration and E4 region's proteins effects?

Disclaimer: I'm neither a genetics professional nor an anti-vax fanatic, I just tried to compare COVID-19 vaccine types currently available on the market and got some questions that I'd like to answer ...
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Why didn't Escobar's hippos introduced in a single event die out due to inbreeding

Today I read a BBC Report about how Pablo Escobar had once imported 4 hippos (1 male, 3 female) into his estate in Colombia for his private zoo. After his downfall, while other species were shipped ...
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Get “DNA” of one parent based on its children [closed]

I'm no biology expert so bear with me, but I've been given a task to estimate alleles of an animal based on the animal's children and the children's other parents. I've looked up Mendel's laws but I'm ...
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Is the number of nucleoli in a nucleus fixed?

A nucleus can have multiple nucleoli. But are there any constraints on the number of nucleoli in a nucleus? Can cells of individuals of different species have a different number of nucleoli? Can ...
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Explanation of “differential transcript usage” (DTU)

This paper describes differential transcript usage as Differential transcript usage (DTU) is a special case of alternative splicing in which a gene’s relative transcript abundance (RTA) profile, the ...
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exercise of gene linkage in genetics

Could you help me solve this problem: AAbbCC is crossed with aaBBcc and the offspring re-crossed with aabbcc. Considering that A and B are linked and their distance is 12 mapping units, while the gene ...
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What does this mean? [closed]

The phenotypic ratio of dihybrid cross 9:3:3:1 can be derived as a combination series 3 yellow: 1 green, with 3 round :1 wrinkled. This derivation can be writtenbas follows: (3 round :1 wrinkled) (...
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Does Darwin's Theory of Evolution refute Terence McKenna theory “Stoned Ape” theory of human evolution?

I haven't read it but I'm asking for a quick answer. As far as I know, Terence McKenna's theory of evolution in humans main concept is that a hominid has tried in their diet psilocybin mushrooms, and ...
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Examples of environmentally influenced gene-expression in humans?

In discussions of the relevant importance of genetic and environmental influences on the development of the individual, it's often stated that the genetic and environmental influences interact. An ...
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Where does the term “cos site” come from?

The word cosmid is derived from cos sites of lambda phages. Why are cos sites called cos sites? What does this "cos" refer to?
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Inheritance of FEVR (Genetic Disease)

If a woman has FEVR and is affected by the disease, what are the chances of her passing the disease to future generations. I read somewhere from a credible source like NIH(I couldn't find the link ...
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The Perfect Predator? [closed]

I’m not a biology major or even studying it in any way so I apologize if this makes no sense. I’m curious, if say the Jurassic Park team came up to you and asked you to genetically engineer the ...
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3 primers to know if Homozygous, Heterozygous or WT

In this imaginary experiment, I am using T-DNA to make an insertional mutagenesis that will get randomly inserted into the DNA where it might get inserted within a gene, disrupting it. In order to get ...
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Why is the number of cells virtually a constant?

Going back to highschool, I learnt about mitosis: in order to renew their cells, eucaryots' cells divide themselves into two copies. But my course didn't cover what moderate the replication. By ...
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Advantages of pain sensation?

The hazards of congenital insensitivity to pain (CIP) are well-known. This question is about the obverse: what selective advantage, if any, does the normal sensation of pain confer? I'm thinking of ...
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Why is cannibalism not an evolutionary stable situation?

In the 'the selfish gene' Dawkins writes (page 109): "The reason lions do not hunt lions is that it would not be an ESS (evolutionary stable situation) for them to do so. A cannibal strategy would be ...
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Can DNA fingerprinting tell you if someone has been genetically engineered?

I am writing a fictional novel about an extensively genetically engineered man, unbeknownst to him, who gets into trouble on a regular basis. The man is physically large and strong, very fast (tiger-...
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Analysis of post transplantation lineage tags

I'm having some trouble understanding some bits of a study, mostly about the Sleeping Beauty system and TARIS model, from this paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408613/ I ...
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Can Cas13 edit DNA

Can Cas13 be used to edit DNA or is it only for RNA? I have tried looking at literature and my understanding is that it can only edit RNA.
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gene mutation occurs on two strands of DNA or just one strand?

Suppose we have one strand with 3'-AAA-5' and the other strand is 5'-TTT-3'. So when point mutation occurs, does it happen to two strands at the same time? e.g. 3'-AAA-5' becomes 3'-AGA-5' and 5'-TTT-...
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Cystic Fibrosis Genetic Risk Determination

Let's say Jane has Cystic Fibrosis and we know her brother doesn't. What are the chances of her brother's future child having CF? (The chances of Cystic Fibrosis in the general population can be taken ...
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Why are Chromosome Territories important?

Chromosomes occupy discrete regions of the nucleus, referred to as 'Chromosome Territories'. This spatial organization is emerging as a crucial aspect of gene regulation and genome stability in health ...
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Balancing selection vs introgression?

Balancing selection can maintain polymorphisms in natural populations for extended periods of evolutionary time. However, in this paper, Dannemann et al. 2016 identify three archaic haplotypes in the ...
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Standard notation for crossings (female, male)

Is there any standard for the notation of a crossing (hybrid) which tells me which part is the mother and which is the father? Example StrainA: egg cell ...
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Fertilization of the human egg- where does our centrosome come from? [closed]

Is there a centrosome in a human egg cell? Is the reason why the egg cell remains paused before meiosis 2 because there isn't a centrosome, and it only divides when the sperm fertilizes it thus it can ...
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x-linked recessive inheritance and correlation for males

I was inspired by a discussion in this thread. Wikipedia lists a number of disorders linked to recessive genes on the x-chromosome. One typical example is red-green color blindness. Now wikipedia says ...
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Can autosomal inheritance follow the rules of linked inheritance?

Sex-linked inheritance occurs, as the name implies, on sex chromosomes, mostly the X chromosomes. Sex-linked inheritance is particularly interesting due to the fact that the set of possible final ...
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How could I make my fish gold?

I'm doing research on how the pigmentation of fish. I want to know how could you change it with the help of genetic modification. I have some Silver Dollar fish (Metynnis argenteus) and I want to make ...
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At what rate do chromosomal rearrangements occur?

How often do chromosomal rearrangements occur? I am interested about these kind of chromosomal rearrangements that are passed on to the descendants, i.e. germ line chromosomal rearrangements. The ...
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What is neutral theory of evolution?

The question is not about the very basics, but more about where the line separating the neutral theory from the rest of population genetics lies. One often reads/hears claims that "the findings ...
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Why/How do Cyanobacteria Produce Toxins?

I've been doing some research on the versatility of nitrogen-fixing cyanobacteria, particularly of the genus Anabaena, and I often run into safety hazards and have to add extra steps to my procedures ...
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How many people are required to maintain genetic diversity?

Imagine humans were to colonize a distant planet and it was a single one-way trip. How many people would they need to bring? Obviously 2 is the minimum, but that would result in a lot of inbreeding. ...
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Questions regarding transformation in bacterial cells

First off, in transformation the donor DNA aligns itself with the complementary bases in the recipient DNA. Now a "perfect" alignment of the donor DNA ( Sorry if my terminologies are ...
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Can Taq polymerase be stored with PCR primers?

I don't think it's possible for TAQ to be stored with the primers, but I'm not sure. This storage wouldn't be long-term (a few days, or a week at most). Thoughts?
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Why does the DNA of Bacillus subtilis not contain DNA families of 20-37 members?

I am reading the book "Molecular biology of the Cell, 6th edition" and in chapter one page 18 the following figure is included I am presuming this figure represents all genes within the ...
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How to figure out frequency of genotypes in generation n+1 AFTER figuring out the recombinants?

I have something that I want to make sure that it makes sense. I am not an expert on population genetics For example: I have population at generation 1 individuals : (A,A,B,D) I know that there was 1 ...
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Are these cats calico?

Calico cats are cats that have 3 fur colors and are always female or males two X chromosomes. I've seen many cats that will have 2 fur colors (one of them is usually white) and another, third, color ...
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Why is a heritability coefficient not an index of how “genetic” something is?

On his blog, Eric Turkheimer writes: [T]aken as a number, a unit of analysis, heritability coefficients are funny things to aggregate on such a massive level. What exactly are we supposed to ...
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In theory, would it be possible to genetically engineer an adult to experience more pleasure or (physical) pain?

(Not sure if this is too close to be acceptable, but this is similar to a question I asked in the neuroscience/psychology stack exchange, but with a focus on the genetic aspect. Might be best to check ...

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