Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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6 views

Systemic Sclerosis links?

What is the link between; vascular damage, Toll-Like Receptors and inflammation in systemic sclerosis?
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Different types of DNA [on hold]

How B-DNA is converted to A-DNA in a less diluted solution? Please also explain the mechanism
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Identify which of the two columns A and B represent gene and chromosome

I am a bit confused on this question in my Textbook (STD 12) and have got all sorts of answers on searching it but I am still not able to comprehend it literally. Can someone answer this and explain ...
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30 views

Do we actually know the Huntington chorea molecular mechanism?

I mean, did we know all genes involucrated on the dynamic mutation, and the protein that are used or it will be affected? I found this paper on chorea genetics from 2016 where literally concludes: ...
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Does haemophilia in men bring about sterility in later stage of life?

In NCERT(books issued by the government of India), it is written that the possibility of a female becoming haemophilic is extremely rare because mother of such individual need to be a carrier while ...
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Why is sickle cell trait expressed in half of all cells rather than all cells containing half-sickled haemoglobin

If sickle cell trait is due to be heterozygous with respect to a single gene mutation on the haemoglobin β-globin chain, why is it the case that ~50% of RBCs are sickled rather than half of the ...
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Which trait does the given Pedigree chart show?

I have a doubt in this pedigree chart , according to me it should be autosomal dominant. But the ans given is X linked recessive , in the case of X linked recessive one daughter should be carrier and ...
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How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share?

How much DNA (or genes) do homo-sapiens and ursus arctos (brown bear) share? There are articles online that indicate that humans share xxx% of DNA with Chimpanzees, bananas, and other assorted ...
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Genetic equilibrium in case of two phenotypes and three alleles with inbreeding and fitness taken in account

Suppose there is an organism with diploid genome. Gen $A$ is represented with three possible alleles $A_1$, $A_2$ and $A_3$. Dominance is complete and the dominance hierarchy of alleles is following: $...
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Is every flower on a plant unique?

I've noticed on my dahlia plants that sometimes there's a flower which looks completely different then the rest . Either color or structural. I dig these bulbs up each fall and keep inside to replant....
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What is the genetic reason that this flower has petals of two different colors?

I have two different varieties of the flower, portulaca: one is bright pink, the other is pure white with pink specks at the centre. Recently a flower bloomed which had 50% of the former and 50% of ...
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Can primers for PCR be duplicated?

Complete beginner question here, don't laugh: If I have some primers that have been synthesized, and I am close to running out of them, is there any way to duplicate them / amplify them / synthesize ...
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chromosome 19 and recombination

Im doing a project with structural variation created by recombination within the human genome during spermatogenesis, where im especially examining intrachromatid homolog recombination. I find that ...
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Why does X inactivation happen?

Is X inactivation really important? Why don’t the dominant genes on one chromosome mask the recessive on the other chromosome? This happens in other sets of chromosomes so why exactly does this happen ...
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What's the difference between the terms “gene map” and “genome”?

It seems some sites arbitrarily restrict "gene map" to only a single chromosome, but others don't. Supposing we don't restrict it to just a single chromosome, is it different from "genome"? Are these ...
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Linkage terminology in drosophila

Consider two linked loci that are 50+ map units apart. I perform a test cross between a female that is heterozygous at both loci to a male that is homozygous recessive. In this case, the phenotypic ...
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Linker DNA and Genetic Expression

So I was reading on linker DNA, and the textbook only describes it in terms of structure. I was wondering if linker DNA can ever contain genes, and if it can, whether it will always be expressed or ...
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Inheritance percentiles

I am aware that the average DNA contribution from each grandparent is 25%, while the possible range is 0%-50%. I found a source citing 18%-32% as the "normal" range but this was undefined. I assume ...
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1answer
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Example of a virus becoming symbiotic with an organism

The human gut has an indispensably beneficial ecosystem of bacteria. What are the examples of a virus that becomes symbiotic with an organism, or even incorporates beneficially into the genome of the ...
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Does intelligence depend more on environment than on genetic factors? [duplicate]

Many have argued that the test of IQ is simply a test of language. The application of the test consists of asking a number of questions. The person should understand the question presented to them and ...
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Is there any evidence that genes which are associated with physically adjacent structures are located near each other within the genome?

I am not sure if there are individual genes for, say, fingers and if so, would such genes be near the genes that affect hand growth? If not "near" in the Euclidean sense, could there be a different ...
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Chromosome naming convention: Why are there chromosomes named “1” and “1A”?

I've been stumbling on multiple genome of birds where there is a "1A" chromosome and a "1" chromosome. For example, the zebra finch has 1A and 4A. What does that mean? Do you have any resource about ...
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The First Polymerase

Knowing that polymerase protein is needed for the transcription of genes, which polymerase is used in the transcription of polymerase protein itself?
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Do all humans have an identical nucleotide sequence for certain proteins, e.g haemoglobin?

All humans have the same sort of proteins in our bodies. Take haemoglobin for example. Is the gene coding for haemoglobin in my body identical to everyone else's gene or is there slight variations ...
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1answer
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What does “genetic correlations” mean as opposed to just correlations?

I'm reading the paper "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior". In Fig. 4 shows "Genetic correlations of same-sex sexual behavior with various ...
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What is the average number of alleles per gene we have today?

Yesterday I was making some calculations, and I started to wonder the average number of alleles per gene the human species have today. The best question would be how many mutations per base or how ...
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Is variation a result of Evolution?

We know that the DNA copying mechanism that replicates DNA during cellular division is not 100% accurate and the resultant errors are the source of variation in the members of a population. At the ...
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Animal Transgensis - biological Implications?

I'm writing a report on the biological Implications of Transgensis of a cow which carried the gene for myelin sheath protein in its milk. I was wondering if anyone would know what sort of biological ...
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What is a Singleton Variant

I'm reading a paper that on a population genetics study where they sequence a number of genomes. The study states that 101 Singleton Variants per individual where found. What does Singleton mean?
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Do conservation oriented genetic database exist?

Are there any projects for the creation of the international genetic database of all endangered species, so we, at least, have a chance to clone them in the future if our current conservational ...
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How does chromosome doubling occur?

Sterile hybrid with genome AB undergoes doubling of chromosome set to form fertile tetraploid with genome AABB. But since A and B is not homologous, synapsis cannot occur at prophase I, so there is ...
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What percentage of Americans have Native Indian ancestry? [closed]

What percentage of americans have native indian ancestry? I tried to find the answer online and it's difficult to search for.
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Tools I can use to find similar genes

What tools are available to estimate the function and purpose of a gene ? I think the right approach is to find similar sequences of genes that we know the function of. All the information I have on ...
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3answers
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Will modern-day insects grow to massive size in a high-oxygen environment?

It's a reasonably well-known fact that insects grew to massive sizes due to the excessive concentration of oxygen in the prehistoric-Earth's atmosphere. If one were to try to recreate this high-...
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Why do I have 95% of chimpanzee's DNA, and only 2% of Neanderthal's DNA? [duplicate]

Excuse me if it is a question with a simply answer, but I don't understand these discoveries, looking a discrepancy from my unknowledge of genetics: I have 95% of Chimapanzee's DNA, and, I have [...
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What could humans do to “see” what dogs smell?

We're able to see a lot of things using computers that we can't see normally: yellow-green, UV light, X-rays, etc. What do we have that harnesses the ability to "see" what dogs smell (e.g., harnessing ...
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General Enhancer Questions (Methylation Patterns, ect.)

I have a biological question(s) for ya'll involving enhancers. 1.) Enhancers work by being the binding sites for TFs. But how does this increase transcription? (Especially when enhancers can be ...
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Probability for a megafauna specimen to exhibit a gene not present in either parent

What is the rough probability for a megafauna specimen to exhibit a gene not present in either parent? I'm looking, ideally, at the chance for one specific individual to be the first in a breeding ...
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1answer
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Estimate for number of genes changed in speciation between a megafauna parent and child species [closed]

At least in terms of a back-of-the-envelope calculation, what is a believable range for the number of gene changes between parent and child species to represent speciation between species of megafauna?...
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Blood and hair follicles from 25 people put on the Moon; enough to regenerate a human population?

Discussion on the question Why were blood and hair follicles from 25 people put on the Moon? calls into question whether this is a stunt or might have any basis in science. There's two parts to my ...
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Why is the size of the human penis not in proportion to that of the rest of the body?

According to this research https://qph.fs.quoracdn.net/main-qimg-2ffcc3b19663af67c96ac1be8f3d6351-c it is more likely for tall men to have large penis but there are still many tall not having large ...
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What are the consequences of less DARC expression as a result of a Duffy weak allele?

According to codegen.eu I'm a carrier of a Duffy weak allele. For SNP rs34599082 I have alleles C and T. T is a rare allele that found is less thatn ~1% of the population. Codegen.eu directs me to ...
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What is the Definition of Homologous Chromosomes? length, gene position are the same or similar? [duplicate]

what is the Definition of Homologous Chromosomes? this post says Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length,...
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DNA and Genes, which consists of which? It seems that the hot answer on quora is different to the nih post

This quora's answer has got 8.3k views and 20 Upvoters. "Genes are a part of the DNA." per nih, "Genes are made up of DNA, which is telling the truth." in my understanding, the quora version ...
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Consider gene is countable, can anyone give a concrete example of “a gene”?

gene is a countable noun but people always say genes, so what is A gene? for instance, Each chromosome contains many genes, so, which part of the chromosome of Escherichia coli could be ...
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How accurate are Illumina microarray chips for genotyping?

What is the error rate for these machines in genotyping (like for 23&me)? What is the chance of a false positive or false negative?
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When is it reasonable to assume selection for an observed change?

In speciation events, a lot of changes seems to appear simultaneously. How can a specific partial changes, occuring together with a lot of other changes, be said to be advantageous or disadvantageous? ...
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Why isn't the human zygote considered a human life how is a living anatomically modern human defined biologically? [closed]

It has 46 chromosomes by default when healthy(Differences almost always are pathological) and has almost every biological functions, processes a Newborn or and Adult person has. It even invades ...
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Examples of environmentally influenced gene-expression in humans?

In discussions of the relevant importance of genetic and environmental influences on the development of the individual, it's often stated that the genetic and environmental influences interact. An ...
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Is presence of air necessary for silica gel to absorb moisture?

I am a biologist currently doing field work where I need to quickly dry leaf samples using silica gel crystals. I use the orange indicating kind that are 2-4mm in size. The setup is like this. I ...