Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Why do I have 95% of chimpanzee's DNA, and only 2% of Neanderthal's DNA? [duplicate]

Excuse me if it is a question with a simply answer, but I don't understand these discoveries, looking a discrepancy from my unknowledge of genetics: I have 95% of Chimapanzee's DNA, and, I have [...
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What could humans do to “see” what dogs smell?

We're able to see a lot of things using computers that we can't see normally: yellow-green, UV light, X-rays, etc. What do we have that harnesses the ability to "see" what dogs smell (e.g., harnessing ...
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General Enhancer Questions (Methylation Patterns, ect.)

I have a biological question(s) for ya'll involving enhancers. 1.) Enhancers work by being the binding sites for TFs. But how does this increase transcription? (Especially when enhancers can be ...
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Allelic dominance and recessiveness [duplicate]

What is the reason for the allelic dominance and recessiveness of a gene? Is it all about the chance or probability of getting the fusion of a particular character ? So how can be there a dominance ...
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Parents' genetic testing before pregnancy [closed]

I need to determine whether I and/or my partner should perform a genetic test prior to pregnancy. I find it difficult to filter and analyze the information available on the Internet. I would like to ...
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44 views

Probability for a megafauna specimen to exhibit a gene not present in either parent

What is the rough probability for a megafauna specimen to exhibit a gene not present in either parent? I'm looking, ideally, at the chance for one specific individual to be the first in a breeding ...
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50 views

Estimate for number of genes changed in speciation between a megafauna parent and child species [closed]

At least in terms of a back-of-the-envelope calculation, what is a believable range for the number of gene changes between parent and child species to represent speciation between species of megafauna?...
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Blood and hair follicles from 25 people put on the Moon; enough to regenerate a human population?

Discussion on the question Why were blood and hair follicles from 25 people put on the Moon? calls into question whether this is a stunt or might have any basis in science. There's two parts to my ...
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Why is the size of the human penis not in proportion to that of the rest of the body?

According to this research https://qph.fs.quoracdn.net/main-qimg-2ffcc3b19663af67c96ac1be8f3d6351-c it is more likely for tall men to have large penis but there are still many tall not having large ...
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How does miRNA change as biomarker after disease remission? [on hold]

I am going to start a research about miRNA and I found it is not only used a biomarker as genetic susbitbilty, but also a response marker. This idea is so unintutive for me that what me to ask: How ...
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Do performance-enhancing drugs alter DNA?

Suppose someone was taking a drug that boosts cognitive performance. Would this change be reflected in his or her DNA? I'm guessing not because the genetic component of IQ is set at birth but I just ...
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What are the consequences of less DARC expression as a result of a Duffy weak allele?

According to codegen.eu I'm a carrier of a Duffy weak allele. For SNP rs34599082 I have alleles C and T. T is a rare allele that found is less thatn ~1% of the population. Codegen.eu directs me to ...
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58 views

What is the Definition of Homologous Chromosomes? length, gene position are the same or similar? [duplicate]

what is the Definition of Homologous Chromosomes? this post says Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length,...
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DNA and Genes, which consists of which? It seems that the hot answer on quora is different to the nih post

This quora's answer has got 8.3k views and 20 Upvoters. "Genes are a part of the DNA." per nih, "Genes are made up of DNA, which is telling the truth." in my understanding, the quora version ...
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Consider gene is countable, can anyone give a concrete example of “a gene”?

gene is a countable noun but people always say genes, so what is A gene? for instance, Each chromosome contains many genes, so, which part of the chromosome of Escherichia coli could be ...
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How accurate are Illumina microarray chips for genotyping?

What is the error rate for these machines in genotyping (like for 23&me)? What is the chance of a false positive or false negative?
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1answer
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Is it reasonable to assume selection for an observed change? [closed]

Assume a gene G plays a role in regard to factors A, B, C and D. Factor A is important on a daily basis. Factor B is important on a hourly basis. Factor C is important on a yearly basis. Factor D is ...
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2answers
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Why isn't the human zygote considered a human life how is a living anatomically modern human defined biologically?

It has 46 chromosomes by default when healthy(Differences almost always are pathological) and has almost every biological functions, processes a Newborn or and Adult person has. It even invades ...
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Examples of environmentally influenced gene-expression in humans?

In discussions of the relevant importance of genetic and environmental influences on the development of the individual, it's often stated that the genetic and environmental influences interact. An ...
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Is presence of air necessary for silica gel to absorb moisture?

I am a biologist currently doing field work where I need to quickly dry leaf samples using silica gel crystals. I use the orange indicating kind that are 2-4mm in size. The setup is like this. I ...
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1answer
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Is there a name for survival of the fittest in a single family? [closed]

Imagine a case where the children of a bird each have a 50% chance of being born blind. But the bird always has on average 4 chicks. So on average 2 will be blind and 2 sighted. (Perhaps this could ...
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Is it possible to breed neanderthals through selective breeding?

I've heard most non-subsaharan africans have neanderthal DNA with it being more prevalent in northern regions, that sometimes 1-4% of the DNA has neanderthal origins. Speaking strictly ...
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What causes cellular differentiation?

Each cell in our body contains identical dna. And, yet some cells become liver cells, some become brain cells etc. How this happens , when all of them has same dna? Is it because of epigenetic control ...
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1answer
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Difference Junk DNA and Pseudogenes [duplicate]

1-Are Pseudogenes and Junk DNA both Non-Coding DNA or they are different entity? How much Pseudogenes & Junk DNA do we have respectively? 2-I read that Non-Coding DNA has functions, my question ...
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Inbreeding depression in Gouldian Finches

I currently breed Gouldian finches, including the yellow mutation. I was lucky to breed 6 youngsters including pure yellow and yellow split. How far can I interbreed the offspring (i.e step brothers/...
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Species diversity in cheese and yoghurt?

There have been studies on the number of species on humans and in various other environments. I was wondering how many species including: viruses, bacteria, yeasts, and fungi inhabit ordinary farm ...
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Is the genetic term “polycistronic” still used in modern biology?

Is the term "cistronic", meaning an ORF on a mRNA, still commonly used in modern genetics? I´ve seen "polycistronic" being applied to prokaryotic mRNA in old textbooks, but I´ve rarely stumbled upon ...
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Confusion about result of monohybrid cross in Mendelian genetics

I was studying monohybrid crosses in genetics where the character considered is stem height. Whenever I came across punnett squares, I used to calculate the probability of the genotype of the ...
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1answer
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If coelocanths are more related to humans than groupers -does a Coelocanth's DNA literally have more sequences in common with a human than a grouper?

Would a coelocanth and a human still have more sequences in common than a coelocanth and a grouper? Would the coelocanth and human dna basically "look" more similar than either would to a ray-finned ...
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1answer
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Easy Hardy Weinberg Equilibrium [duplicate]

Hi My friend and I get 2 different answers to this question. I would like to know how to calculate the value of q. My friend says that 500/1500=q because there are 500 recessive alleles in the ...
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1answer
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What is the use of having a surrogate mother in animal cloning?

In animal cloning, an ovum is collected by an animal and processed to form an embryo after fusion, which is going to be inserted to a surrogate mother. So my question is that why can't the embryo be ...
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Studying the epigenetic variability, can I use SNPs?

So, I'm trying to study the effects of epigenetic variability on the brain structure. Can I use SNPs associated with a gene's higher expression to compute the likelihood of that gene being expressed ...
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What does “dissection-based microscopy” mean as described here, and how can it give genetic information?

The Phys.org article 'DNA microscopy' offers entirely new way to image cells references the new Open Access paper in Cell DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical ...
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Are chromosomal microdeletions passed on?

I've been looking around but can't find a clear answer: are chromosomal micro-deletions passed on (hereditary) or not?
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What the “due to” means in the definition of heritability?

According to Wray and Visscher, heritability is formally defined as the proportion of phenotypic variation (VP) that is due to variation in genetic values (VG). My question is, what does “due to” ...
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For eQTL analysis, is it ok to combine all the ethnic groups?

I am performing eQTL analysis, and wish to be answered for a quick question. In conducting eQTL analysis, biologically, is it fine to include subjects from all ethnic groups (to increase statistical ...
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Number of DNA strands per chromosome

As I was reading Griffith's Introduction to genetic analysis this evidence was provided for single DNA makes single chromosome. Eventually geneticists demonstrated directly that certain chromosomes ...
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1answer
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What species would this be?

A common way to define species can be found on Wikipedia: A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can ...
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How can I calculate Fst, Gst, and Nei diversity index?

I got different polymorphisms of Cucumber mosaic virus in different regions of its genome from different libraries of RNAseq. This virus have two coding regions which are 3A and CP regions. I have ...
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Is it possible to change the DNA of all the cells of an adult human [closed]

The process of making and transferring changes is pretty straightforward relatively speaking in an embroyo. You change the DNA of one cell and all the cells now inherit this change. But let's say ...
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Meaning of letter “c” in description of mutation: “Homozygous c.195C>G; (p.Cys65Trp)”

In a table in a paper titled Cerebral folate deficiency: Analytical tests and differential diagnosis, there's the following description of a mutation in a patient: Homozygous c.195C>G; (p.Cys65Trp)...
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If some humans inherited 3% of Neanderthal DNA, why are we 99.9% same genome? [duplicate]

Many sources say that humans are 99.5 to 99.9 percent the same. Also some sources state that some humans have 3.4% Neanderthal DNA and some don't share those genes. Why is that?
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Why can't a genetically sound human stay alive for an indefinite amount of time given all the ideal conditions? [duplicate]

I have read that even if we can control our food and lifestyle and keep things as ideal as possible, there are other factors beyond our control like effects from neutrinos passing through our body ...
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Are all fusion genes somatic in origin or can fusion genes be germline?

Fusion genes should have an origin.These are essentially hybrid genes that are translocated in its entirety. Eg. BCR-ABL, EML4-ALK are known to be implicated in cancer pathogenesis. Do these ...
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1answer
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Do human genes get affected by irregular sleep and other factors

I'm new here so please go easy on me. Do our genes-the ones that carry our appearance, intelligence and other traits get destroyed or lost due to irregular sleep, excessive body heat, smoking, ...
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How are haplotype blocks different from genes?

According to Cardon et al. 2003, a haplotype block is A discrete chromosome region of high linkage disequilibrium and low haplotype diversity. It is expected that all pairs of polymorphisms ...
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Is it possible to Clone a Dinosaur with a full strand of their DNA? [duplicate]

If you have a full strand of Dinosaur DNA would it be possible to make it living and hatch a dinosaur? Or would it be a failure? Could you use a bird or alligator, for replacein
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How do crossbreeding with Neanderthals affect the genetic difference between ethnic groups?

I do not know exactly how much Neanderhtal/Denisova DNA non-subsaharan peoples carry around today, but I have heard figures of less than two percent in Europe, up to three percent in East Asia and ...
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what are best methods for mrsa screening in hospital?

methods for screening MRSA are based on PCR (mecA detection) and MRSA latex test and culture. I need to know sensitive, specific and cost-effective methods for diagnosis MRSA infection on one work day ...
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2answers
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What's the difference between reaction norms and phenotypic plasticity?

I'm trying to understand better these two concepts, but I cannot see a clear difference yet. Reaction norm: "set of phenotypes that can be produced by an individual genotype when exposed to different ...