Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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78 views

When is it reasonable to assume selection for an observed change?

In speciation events, a lot of changes seems to appear simultaneously. How can a specific partial changes, occuring together with a lot of other changes, be said to be advantageous or disadvantageous? ...
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Why these 2 dots frequently occur in dog's eyebrows? Do it serve/served any advantage?

It has been wonder me, in spite of so-many variations in color-patterns in dogs; these 2 dots (1 on each eyebrow) remains frequently occurring. Dog-1 Dog-1 close up. this one has a white dot. ...
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41 views

What does “genetic correlations” mean as opposed to just correlations?

I'm reading the paper "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior". In Fig. 4 shows "Genetic correlations of same-sex sexual behavior with various ...
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What is the average number of alleles per gene we have today?

Yesterday I was making some calculations, and I started to wonder the average number of alleles per gene the human species have today. The best question would be how many mutations per base or how ...
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Animal Transgensis - biological Implications?

I'm writing a report on the biological Implications of Transgensis of a cow which carried the gene for myelin sheath protein in its milk. I was wondering if anyone would know what sort of biological ...
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1answer
74 views

What is a Singleton Variant

I'm reading a paper that on a population genetics study where they sequence a number of genomes. The study states that 101 Singleton Variants per individual where found. What does Singleton mean?
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193 views

What is the expected amount of DNA shared by first cousins and the people between them in a family tree?

What is the expected amount of DNA that is shared by all of the people between first cousins, including the first cousins, in a family tree?
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How does chromosome doubling occur?

Sterile hybrid with genome AB undergoes doubling of chromosome set to form fertile tetraploid with genome AABB. But since A and B is not homologous, synapsis cannot occur at prophase I, so there is ...
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1answer
33 views

What percentage of Americans have Native Indian ancestry? [closed]

What percentage of americans have native indian ancestry? I tried to find the answer online and it's difficult to search for.
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Why do people with type O blood have anti-A and anti-B antibodies?

People with type O blood have anti-A and anti-B antibodies, even without receiving a transfusion. Why?
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1answer
48 views

Tools I can use to find similar genes

What tools are available to estimate the function and purpose of a gene ? I think the right approach is to find similar sequences of genes that we know the function of. All the information I have on ...
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3answers
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Will modern-day insects grow to massive size in a high-oxygen environment?

It's a reasonably well-known fact that insects grew to massive sizes due to the excessive concentration of oxygen in the prehistoric-Earth's atmosphere. If one were to try to recreate this high-...
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What could humans do to “see” what dogs smell?

We're able to see a lot of things using computers that we can't see normally: yellow-green, UV light, X-rays, etc. What do we have that harnesses the ability to "see" what dogs smell (e.g., harnessing ...
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Why do I have 95% of chimpanzee's DNA, and only 2% of Neanderthal's DNA? [duplicate]

Excuse me if it is a question with a simply answer, but I don't understand these discoveries, looking a discrepancy from my unknowledge of genetics: I have 95% of Chimapanzee's DNA, and, I have [...
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Why replication collapse but not stall leads to DNA break?

I have been looking into the concept of replication dynamics and was wondering why collapsing but not stalling leads to a DNA break.
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General Enhancer Questions (Methylation Patterns, ect.)

I have a biological question(s) for ya'll involving enhancers. 1.) Enhancers work by being the binding sites for TFs. But how does this increase transcription? (Especially when enhancers can be ...
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Estimate for number of genes changed in speciation between a megafauna parent and child species [closed]

At least in terms of a back-of-the-envelope calculation, what is a believable range for the number of gene changes between parent and child species to represent speciation between species of megafauna?...
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49 views

Probability for a megafauna specimen to exhibit a gene not present in either parent

What is the rough probability for a megafauna specimen to exhibit a gene not present in either parent? I'm looking, ideally, at the chance for one specific individual to be the first in a breeding ...
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Blood and hair follicles from 25 people put on the Moon; enough to regenerate a human population?

Discussion on the question Why were blood and hair follicles from 25 people put on the Moon? calls into question whether this is a stunt or might have any basis in science. There's two parts to my ...
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What does “dissection-based microscopy” mean as described here, and how can it give genetic information?

The Phys.org article 'DNA microscopy' offers entirely new way to image cells references the new Open Access paper in Cell DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical ...
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Why is the size of the human penis not in proportion to that of the rest of the body?

According to this research https://qph.fs.quoracdn.net/main-qimg-2ffcc3b19663af67c96ac1be8f3d6351-c it is more likely for tall men to have large penis but there are still many tall not having large ...
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6answers
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Do apes and humans share 99% of DNA or 99% of genes? What is the difference?

I made an answer on the Scifi.SE that can be read here. It is about how the characters in the story Jurassic Park might have gotten DNA for all the species shown. In my answer, I said this: Apes ...
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How many genes do we share with our mother?

Somewhere I have read we share more than 99% of our genes with every other other person and 98% of our genes with chimpanzees. What does this mean? Don't we share 50% of our genes with our mother and ...
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What is the Definition of Homologous Chromosomes? length, gene position are the same or similar? [duplicate]

what is the Definition of Homologous Chromosomes? this post says Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length,...
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What are the consequences of less DARC expression as a result of a Duffy weak allele?

According to codegen.eu I'm a carrier of a Duffy weak allele. For SNP rs34599082 I have alleles C and T. T is a rare allele that found is less thatn ~1% of the population. Codegen.eu directs me to ...
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DNA and Genes, which consists of which? It seems that the hot answer on quora is different to the nih post

This quora's answer has got 8.3k views and 20 Upvoters. "Genes are a part of the DNA." per nih, "Genes are made up of DNA, which is telling the truth." in my understanding, the quora version ...
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Consider gene is countable, can anyone give a concrete example of “a gene”?

gene is a countable noun but people always say genes, so what is A gene? for instance, Each chromosome contains many genes, so, which part of the chromosome of Escherichia coli could be ...
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How accurate are Illumina microarray chips for genotyping?

What is the error rate for these machines in genotyping (like for 23&me)? What is the chance of a false positive or false negative?
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Why isn't the human zygote considered a human life how is a living anatomically modern human defined biologically? [closed]

It has 46 chromosomes by default when healthy(Differences almost always are pathological) and has almost every biological functions, processes a Newborn or and Adult person has. It even invades ...
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Is presence of air necessary for silica gel to absorb moisture?

I am a biologist currently doing field work where I need to quickly dry leaf samples using silica gel crystals. I use the orange indicating kind that are 2-4mm in size. The setup is like this. I ...
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1answer
49 views

Is there a name for survival of the fittest in a single family? [closed]

Imagine a case where the children of a bird each have a 50% chance of being born blind. But the bird always has on average 4 chicks. So on average 2 will be blind and 2 sighted. (Perhaps this could ...
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2answers
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Is it possible to breed neanderthals through selective breeding?

I've heard most non-subsaharan africans have neanderthal DNA with it being more prevalent in northern regions, that sometimes 1-4% of the DNA has neanderthal origins. Speaking strictly ...
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Are mutations a source of genetic variation?

Here is a question from the book SAT II Success Biology E/M (where the SAT is the exam taken by the American high school students): Which of the following statements is true about mutations? (A) ...
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What causes cellular differentiation?

Each cell in our body contains identical dna. And, yet some cells become liver cells, some become brain cells etc. How this happens , when all of them has same dna? Is it because of epigenetic control ...
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1answer
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Difference Junk DNA and Pseudogenes [duplicate]

1-Are Pseudogenes and Junk DNA both Non-Coding DNA or they are different entity? How much Pseudogenes & Junk DNA do we have respectively? 2-I read that Non-Coding DNA has functions, my question ...
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1answer
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Is brachydactyly due to mutation?

I have this so called "clubbed thumbs"also known as brachydactyly. It is of D-type. I searched for it on internet and found that it is a dominant inherited disease. But to my surprise,none of my ...
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Is the genetic term “polycistronic” still used in modern biology?

Is the term "cistronic", meaning an ORF on a mRNA, still commonly used in modern genetics? I´ve seen "polycistronic" being applied to prokaryotic mRNA in old textbooks, but I´ve rarely stumbled upon ...
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Inbreeding depression in Gouldian Finches

I currently breed Gouldian finches, including the yellow mutation. I was lucky to breed 6 youngsters including pure yellow and yellow split. How far can I interbreed the offspring (i.e step brothers/...
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Species diversity in cheese and yoghurt?

There have been studies on the number of species on humans and in various other environments. I was wondering how many species including: viruses, bacteria, yeasts, and fungi inhabit ordinary farm ...
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Confusion about result of monohybrid cross in Mendelian genetics

I was studying monohybrid crosses in genetics where the character considered is stem height. Whenever I came across punnett squares, I used to calculate the probability of the genotype of the ...
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3answers
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What makes an E.coli an E.coli, genotype or phenotype?

According to this paper, among 61 strains of E. coli they studied only 6% of the genes are common in all. Which means that the overwhelming majority of the genes are not shared. And wikipedia ...
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If coelocanths are more related to humans than groupers -does a Coelocanth's DNA literally have more sequences in common with a human than a grouper?

Would a coelocanth and a human still have more sequences in common than a coelocanth and a grouper? Would the coelocanth and human dna basically "look" more similar than either would to a ray-finned ...
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In marine DNA viral diversity studies, what would “paradigm of rampant mosaicism” refer to?

The recent paper in Cell Marine DNA Viral Macro- and Microdiversity from Pole to Pole describes the (huge) new Global Ocean Viromes 2.0 (GOV 2.0) dataset. In the Results and Discussion section, the ...
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What's the exact meaning of and how to derive the coefficient of the path from sire to offspring?

According to Wright's Coefficients of Inbreeding and Relationship, the coefficient of the path from sire to offspring is given as $p_{o \cdot s}=\frac{1}{2}\frac{\sqrt{1+F_s}}{\sqrt{1+F_o}}$ But ...
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What is the use of having a surrogate mother in animal cloning?

In animal cloning, an ovum is collected by an animal and processed to form an embryo after fusion, which is going to be inserted to a surrogate mother. So my question is that why can't the embryo be ...
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Easy Hardy Weinberg Equilibrium [duplicate]

Hi My friend and I get 2 different answers to this question. I would like to know how to calculate the value of q. My friend says that 500/1500=q because there are 500 recessive alleles in the ...
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1answer
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Studying the epigenetic variability, can I use SNPs?

So, I'm trying to study the effects of epigenetic variability on the brain structure. Can I use SNPs associated with a gene's higher expression to compute the likelihood of that gene being expressed ...
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1answer
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Are all fusion genes somatic in origin or can fusion genes be germline?

Fusion genes should have an origin.These are essentially hybrid genes that are translocated in its entirety. Eg. BCR-ABL, EML4-ALK are known to be implicated in cancer pathogenesis. Do these ...
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What is Mendelian Segregation and how is it related to the Hardy-Weinberg equilibrium?

I can't find the exact definition of Mendelian segregation. In addition, I am wondering how it is related to the Hardy-Weinberg equilibrium?
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Are chromosomal microdeletions passed on?

I've been looking around but can't find a clear answer: are chromosomal micro-deletions passed on (hereditary) or not?