Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Would our body adapt to changes that are not in our DNA?

If a person was to undergo a treatment or surgery at a very young age, that significantly reduced their final height, would the rest of their body adjust to the sudden change? If not; because our arms’...
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What are the advantages of sexual reproduction over asexual reproduction? [closed]

What are the advantages of sexual reproduction over asexual reproduction? How does variation influence ecological and evolutionary success?
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Linked genes outcomes in offspring

This question is from a genetics session in my university: The test cross between a plant with smooth and yellow seeds and a plant with wrinkled and green seeds gives the following results: 140 ...
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Probability of carrying an autosomal recessive trait given both parents are carriers

I recently came across a question that asked for the probability of having a child with an autosomal recessive trait, namely cystic fibrosis. From various parts of the question, we can conclude that ...
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Genetic Inheritance [closed]

With suppression in mind consider the following in a system that requires two genes (and their products) to produce a function or phenotype: The products of the two genes are both necessary and ...
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How do eukaryotes terminate transcription? (clarification on Campbell Biology)

I'm having trouble understanding how eukaryotes terminate transcription. Studying Campbell Biology (pg. 342, 10th ed.), I read: In eukaryotes, RNA polymerase II transcribes the polyadenylation ...
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Meaning of Phred score - probability of base calling error

I learned that Phred quality scores are logarithmically linked to error probabilities. For example, if Phred assigns a quality score of 10 to a base, the chances that this base is called incorrectly ...
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Are there any DNA base sequences that are shared by every living being that we know of? And if yes, are some of those sequences “silent”?

In "every living being" I am not including viruses as another question already answered that. I have read that some part of the DNA sequences of humans and other animals/plants are "silent" as in not ...
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Why does the definition of a “gene” require it to have a product?

In a textbook, I found the following (emphasis in the original): At this point, we can provide a molecular definition of a gene as a sequence of DNA that specifies production of a functional ...
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Transcription - strands, directions [duplicate]

I am hoping that you can help me improve my understanding of transcription. :) I have tried searching for the answers to all of these questions online already, but I have either had trouble finding ...
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126 views

How does DNA code for the actual *shape* of individual body parts/areas (NOT segments or Hox genes)?

Just to save the trouble - I am not asking for general information on how DNA codes for proteins and definitely not how Hox genes work. I have a very good understanding of the evolutionary process and ...
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36 views

What do the haploinsufficiency scores in the clinVar database represent?

I understand that haploinsufficiency occurs when one of the two copies of a gene is mutated to the point of being unusable, and the single copy remaining is unable to cope with the cell's demands for ...
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Online phylogenetic tree of human lineages

I am looking for a source of information about the diversity of human lineages and their relationships. With a quick google search it is easy to find this type of tree A perfect online resource ...
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Why do some animals have beards?

Why do some animals such as some Goats, Ibex, Orangutan etc, have long well-shaped beard like men?
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What is the number of DNA strands per cell?

I wonder if each cell possess only one strand of DNA which according to my book is more than "7 feet" long(if uncoiled), then why does human has 46 chromosomes which are actually coiled chromatin (DNA ...
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Why are GC-rich regions less condensed than GC-poor regions?

As far as I know, chromatin consists of two kinds: Heterochromatin is more condensed so translational factors have less access to this region, and this region is poor in GC. Euchromatin is less ...
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Does reversion of resistant strains to wild-type only occur when no more drug pressure is exerted

We always read that wild-type reversion of a resistant strain occurs when no more drug pressure is exerted. Could resistance reversion also occur under drug pressure, but from a drug other than the ...
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Factors affecting which chromosome will come from the father

Tell me please. In course of biology, I remember that a man has XY chromosomes, and a woman has only X. Accordingly, depending on which chromosome comes from Father(man) Y or X, a girl (XX) or a boy (...
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DNA of identical twins

I read an article which says that identical twins have 100% similarity between their DNA, but they have different fingerprints. Does that mean the DNA is different in the fingers? What body features ...
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Is bi-allelic gene expression random?

Supposing we have the genotypes “Aa”, “AA”, and “aa”... which are not mono-allelic (not imprinted and not X-inactivated). Does the dominance of the “A” allele over “a” allele affect which gene is ...
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107 views

What is the most genetically complex organism?

I understand that new genomes are being sequenced ever day and these answers replace themselves often; although as of today, what has been proven to be the most genetically complex organism (Other ...
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Do genes play a role in the athleticism and shape of a person?

I am an Indian with a small thin stature with some deposition of fat around my belly.I was wondering if genes play a role in fat deposition in the body for Indian, Chinese, European or African people. ...
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311 views

Is there some genetic variance underlying music appreciation?

Is there any research done on the genetic variance for Music appreciation? If not, why is there no genetic variance for this trait?
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Are there examples of Apis mellifera of different colors?

Re: my previous species-identification question, What species is this gray bee? I'm still curious: Are there any recorded/reported cases of either albino Apis mellifera, or at least with ...
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How do mutations with very little fitness benefit get fixed?

I have one little issue with evolutionary theory that I have not been able to understand. Suppose genetic mutations happen from generation to generation. Nevertheless, from one generation to the next ...
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Does low gravity exposure to early stages of human fetus have potential to unloc unused genetic information from earlier stages of evolution?

The title seems quite self explanatory but let me elaborate. New mutations do take a very long time and many generations to occure in the genetic code. But our genetic code already holds all the ...
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Is it possible that by mutation a human could see infrared or other 'colours'?

Incoming light reacts with the several types of cone cells in the eye. In humans, there are three types of cones sensitive to three different spectra, resulting in trichromatic color vision. Each ...
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Size constraints on CRISPR guide RNA

I had a quick questions on the size limitations of a CRISPR guide. More specifically on the shorter end. Can I make a guide that is say 7-10bp and still have an active complex? I transfect using an ...
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Difference between crossover rate and recombination rate?

I am not a biology student and therefore, need clarification if crossover rate and recombination rate are the same thing. So if the text says 'recombination rate per base pair per generation' or '...
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The human has 46 double chromosomes or simple chromosomes?

What I mean: does the human cell have 46 of these: or 46 of these: Thank you in advance.
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Convergence compared to genetic distance

Is there an information (preferably in the form of a chart, though anything will do) comparing convergent evolution to how closely related the 2 species are on the tree of life. My searches for ...
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346 views

Double stranded RNA Single stranded DNA

I have seen in textbooks referring to ds RNA and ssDNA. How a RNA can be double stranded and likewise how a DNA can single stranded and if they do exist why are there names not interchanged?
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What is the genetic background for fast metabolism?

I am wondering if it is possible that people with very fast metabolism have some genetic mutation. There are people who can eat a lot while others would definitely get fat with such a diet. In other ...
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Drosophila grey / yellow

I am studying biology by myself via distance-learning. I have been trying to solve the following problem for a while now and hoped you could help me. As this is "homework" I would appreciate hints ...
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Could we breed a dog to the size of a thumb?

We've gotten from a wolf to a small breed such as a chihuahua. So the question is: can we go even further and have a dog as small as a thumb (adult dog)? If not, what are the factors that limit the ...
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1answer
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Genetics, sickle cell anemia

Sickle cell anemia is autosomal recessive. Then Why is it an example of codominant alleles? I thought a person with sickle cell trait is heterozygous because one of his/her alleles is recessive and ...
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35 views

How to identify whether something is in linkage disequilibrium?

If the following loci indicated the presence of an SNP in flu strains, is Locus 2 and Locus 3, which are located 10 bp apart in linkage disequilibrium? "When alleles and molecular markers are ...
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When gene editing are both chromosomes in a pair changed?

Sorry for the possibly confused question, my knowledge of genetics is limited to medical training only but I have a question. Are gene editing techniques such as CRISPR used on both of the ...
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What do the signs +/+ +/- mean in this image?

I don't understand what this graph is supposed to explain, especially what the signs +/+ or -/- mean. I just know it characterises some rats.
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How can seedless fruits not be GMO?

Biology is the closest I could find to botany on SE. Grafting can not occur naturally and so if a fruit does not have seeds there is no way it could reproduce in nature. That logic makes complete ...
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How Would I Isolate and Amplify a Viral Enzyme? [closed]

what procedures would I use to isolate and amplify integrase? If I am trying to study the integrase enzyme which is found in HIV how would I 1) destroy the viral capsule to release its contents. 2) ...
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Why don't rates of cancer increase generation to generation?

As cells divide, they accumulate mutations that can sometimes cause cancer. Gametes have to divide like any other cell, and thus generation to generation mutations should accumulate in people's ...
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Is it possible in modern biology to make any person's identical twin (or genetical clone) using his DNA?

I was told by a Biotech professor (who came in our college for a guest lecture) that Bio Technology has now become so advanced that if we want to make an identical twin (or Genetical DNA Twin) of a ...
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Finding intensity of selection against dominant homozygotes

I was looking at some Olympiad questions and came across the following: If the frequency of a completely recessive allele is $0.2$ and it remains unchanged from generation to generation due to ...
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Why don't restriction endonucleases digest transformed plasmids?

In the textbook that I'm using, it explains that bacteria does not digest its own chromosomal DNA because the sites that would be cut by its own endonuclease are methylated. Is there a similar ...
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Which enzyme is Nick Lane referring to?

In Life Ascending the author, Nick Lane, refers to an enzyme in his introduction: '' It concerns an enzyme (a protein that catalyses a chemical reaction) that is so central to life that it is found ...
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How is a specific fragment isolated for PCR amplification?

For background I am interested in studying engineering applications of a specific protein, which is not commercially available. My end goal is to express the gene for the protein in bacterial cells, ...
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Why are males more likely than females to have autism spectrum disorder?

The male to female ratio in autism spectrum disorder is around 4:1. However it seems ASD is not a simple X-linked disorder. Then how is it possible males are more susceptible than females, if the ...
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How does further hybridization affect fertility?

Numeruous scientific sites state that hybrids (like mules) are infertile. On the other hand, ligers are known to mate with both tigers and lions and still have viable offspring. So my question is: if ...