Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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231 views

How do parents give their offspring a chromosome?

Whenever an organism sexually reproduces, it gives its offspring one chromosome from each of its pairs of chromosomes. My questions are Is this done randomly? Is it uniformly random? If so, what ...
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461 views

How should one interpret heritability? Is it related to $R^2$?

From Wiki: Heritability estimates are often misinterpreted if it is not understood that they refer to the proportion of variation between individuals on a trait that is due to genetic factors. It ...
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236 views

Need of X or Y chromosome protein after meiosis

After meiosis each spermatid get either the X chromosome or the Y chromosome. I know that the 4 spermatids formed from 1 spermatogonia are connected by cytoplasm and so the proteins made by X or Y ...
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2answers
725 views

Explain allelic complementation at molecular level

I know that Allelic complementation is a phenomenon where two recessive loss-of-function allele generate a functional gene product by compensating each others' defect. But I don't get how do they ...
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453 views

What does min mean?

I read that "trp operon is located at 27 min on E.coli chromosome." What does "min" mean ?
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289 views

Inbred mice has no severe phenotype outcome?

Why does 20 generation of inbred mouse have no particular strange phenotypes, but on the contrary, when on purposely inbreed dogs or tigers for specific phenotype cause severe deformation of the bone ...
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114 views

X-recessive disorders and genetic markers

Please observe the following pedigree of a family with a x-recessive disease (bleeder disease). The A's are genetic markers so close to the disease gene that recombination is negligible. I ...
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239 views

Mutations/deletions with CRISPR

I need to stop some protein from being active and searching for some universal way to do so. In mammalians. With CRISPR it is possible to knock-out the entire gene. But it's a little complicate (...
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3answers
819 views

Sense and anti sense strand

Why the sense strand is only involved in transcription though the antisense strand just has the compliment strand of the sense strand?
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43 views

Mendelian dominant trait involved with Hypodontia [closed]

If the absence of teeth is a dominant trait, then why is it not seen in generations? My teacher taught that absence of teeth is a mendelian dominant trait, but why don't we see this trait if it is ...
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105 views

If evolution is true, how do all organisms have varying amount of chromosomes? [duplicate]

I thought genetic mutation changes genes and therefore evolution happens, but it doesn't explain how chromosomes are created/removed if the first organism had a set amount and now all the organisms ...
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95 views

How can co-dominant alleles work in flower petals?

I am studying gene inheritance, and I understand complete dominance/co-dominance and incomplete dominant penetrance in flowers. I know how to recognize each case. However, how does co-dominance work?...
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36 views

What are primary reasons for the failure to localise/anchor sequences in genome assemblies?

My question concerns the incorporation of individual sequence reads into chromosomes during gene sequencing projects, especially those with larger genomes such as Drosophila melanogaster or Homo ...
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302 views

IBD-value in pedigree with inbreeding

I have a question about IBD. Please see the figure below. How many pairs of alleles are IBD for X and Y, or what is the IBD value for X and Y. Is it four (4)? I have seen it to be maximally 2, but ...
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3answers
688 views

Double stranded RNA Single stranded DNA

I have seen in textbooks referring to ds RNA and ssDNA. How a RNA can be double stranded and likewise how a DNA can single stranded and if they do exist why are there names not interchanged?
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49 views

Probability for a megafauna specimen to exhibit a gene not present in either parent

What is the rough probability for a megafauna specimen to exhibit a gene not present in either parent? I'm looking, ideally, at the chance for one specific individual to be the first in a breeding ...
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132 views

Neutral genetic mutations in eukaryotic cells [closed]

Why are most mutations in eukaryotic cells neutral? i.e. have no effect on the phenotype.
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59 views

Estimate for number of genes changed in speciation between a megafauna parent and child species [closed]

At least in terms of a back-of-the-envelope calculation, what is a believable range for the number of gene changes between parent and child species to represent speciation between species of megafauna?...
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64 views

Why is sickle cell trait expressed in half of all cells rather than all cells containing half-sickled haemoglobin

If sickle cell trait is due to be heterozygous with respect to a single gene mutation on the haemoglobin β-globin chain, why is it the case that ~50% of RBCs are sickled rather than half of the ...
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2k views

What are sex linked traits?

Which of the two definitions of sex-linked trait is correct? Traits controlled by genes present on the non-homologous region of sex chromosomes are called sex-...

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