Questions tagged [genetics]
Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.
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What's the difference between reaction norms and phenotypic plasticity?
I'm trying to understand better these two concepts, but I cannot see a clear difference yet.
Reaction norm: "set of phenotypes that can be produced by an individual genotype when exposed to different ...
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1answer
59 views
Where can I find DNA decryption research? [closed]
What is the name of the science that studies the mathematics of DNA?
Where can I learn about maths, statistics, types of code, numbers, patterns and graphs for genes and information found in DNA?
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How does a neutral allele change relative to a nearby allele under selection?
Suppose I'm looking at a gene being selected against (A) that's decreasing at a rate ($\Delta$P). If there's a nearby allele that is neutral (B) am I correct to assume that B will decrease with A at a ...
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1answer
45 views
Can Females Songbirds Have Male Plumage?
Male birds are colorful for courtship displays, females are dull for camouflage. But, is written in a website somewhere that sometimes, when females birds are sterile, they grow male plumage due to ...
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2answers
31 views
Is there natural occurrence of induced pluripotency / expression of Yamanaka factors and what is the evolutionary explanation of that?
Is there natural biological processes in which the full (full reprogramming into pluripotent state) or partial (partial reprogramming, stopped before point-of-no-return, preserving the functional ...
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1answer
43 views
is it possible for a son to inherit an allele on a Y chromosome?
Obviously, the only way for one to be male is to inherit the Y chromosome, but are there alleles on the y chromosomes? Or is it just automatically the recessive trait without an allele.
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2answers
138 views
Rationale behind Most Recent Common Ancestor (MRCA)?
My main question is this -
I heard Richard Dawkins say in a video that after 1000s of years, any given individual alive today will be either an ancestor to ALL of the humans (in that future time) or ...
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0answers
25 views
N value in a GWAS?
Just like the title says. I am reading about a GWAS but I don't know much about them. I understood most of it but I couldn't figure out what the "n" value was.
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0answers
57 views
Recombination due to crossover, outcome?
Garden peas normally have 7 pairs of chromosomes (n=7, 2n=14). Please calculate how many different types of gametes can be produced through the meiotic process if no crossover happens. If cross-over ...
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0answers
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Need help to determine % difference between DNA-strand from two different haplotypes. Known nucleotide diversity and more
Backround:
229 DNA sequences
493 bp in length
Haplotype diversity: 0.9956
Average number of nucleotide differences: 12.50544
Polymorphic sites: 145
Nucleotide diversity: 0.02426
Is it possible ...
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1answer
40 views
How to search for a DNA sequence in a genome on ENA (European Nucleotide Archive)?
I have to do a search for small DNA sequences in the genome of an organism in ENA. I have the accession number and project id. However, I can't download the whole genome because of the download size ...
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1answer
46 views
What is the cause of “imbalanced” linkage disequilibrium?
With perfect linkage disequilibrium ($D' = 1, R^2 = 1$), you might have the following table of counts for the alleles:
B b
A 100 0
a 0 100
With "...
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1answer
47 views
Understanding genetic similarity in humans [duplicate]
I was reading "Blueprint" by Robert Plomin (online preview on webpage) and got stuck when I got to these two sentences in the prologue:
"We are the same as every other human being for more than 99 ...
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2answers
44 views
Phenotypes caused by mutations in mitochondrial DNA?
Will mutations in mitochondrial DNA necessarily affect phenotypes?
I have some cursory knowledge of serial endosymbiotic cell theory, and find it difficult to consider that the DNA of the former ...
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2answers
108 views
In marine DNA viral diversity studies, what would “paradigm of rampant mosaicism” refer to?
The recent paper in Cell Marine DNA Viral Macro- and Microdiversity from Pole to Pole describes the (huge) new Global Ocean Viromes 2.0 (GOV 2.0) dataset.
In the Results and Discussion section, the ...
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0answers
15 views
How do researchers define the region a lead SNP encompasses?
As I understand it, a lead SNP captures the variance for all unmeasured SNPs in a region due to it's low p-value and high linkage disequilibrium. However, in different papers the region size differs (...
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1answer
30 views
How to do a nucleic acid or genome and amino acid search [closed]
I have been looking to find a database where i can search for genome and amino acid search. Are there any open source databases available for the same.
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2answers
31 views
Are SNPs always in linkage disequilibrium with other SNPs
Is it possible to have a SNP that is not found is be non-randomly associating with any other SNP?
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2answers
50 views
Is complete dominance actually a genotypic process?
An example often stated for codominance is blood groups, where both alleles version of the protein is expressed and can be found in the cell membrane.
An example of incomplete dominance often given ...
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3answers
179 views
Is DNA actually like source code repository?
So after reading articles like "People Use Just 8.2% of Their DNA" etc., and thinking a bit... I got this idea:
What if DNA is actually like a software source code repository? You know, it has "...
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1answer
46 views
skin colouration in thalassemia
Now when i was studying about thalassemia, I read that anaemia is its major characterstic. I can understand that fact. But it was also written that the skin gets pale.
Wikipedia says that the skin ...
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0answers
25 views
Absorbance anomaly
The standard concentration for absorbance of 1 for ssDNA is 33 ug/ml, while for RNA it is 40 ug/ml. I can't find the reason for the difference in this value for these two macro-molecules. My professor ...
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1answer
34 views
What are primary reasons for the failure to localise/anchor sequences in genome assemblies?
My question concerns the incorporation of individual sequence reads into chromosomes during gene sequencing projects, especially those with larger genomes such as Drosophila melanogaster or Homo ...
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1answer
47 views
What is the gene for height?
Height doesn't seem to be linked to sex, which is surprising. I have seen ways to predict children's height and it involves taking the average of both parents height. Upon my search, I did not find ...
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1answer
65 views
x-linked recessive inheritance and correlation for males
I was inspired by a discussion in this thread. Wikipedia lists a number of disorders linked to recessive genes on the x-chromosome. One typical example is red-green color blindness. Now wikipedia says ...
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4answers
179 views
What's the benefit of the average human body temperature?
Why would the body choose a resting temperature of 36.1c to 37.2c? It seems a very inefficient mechanism of survival considering the typical ambient temperatures on Earth. If there is a benefit to ...
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1answer
72 views
How to download different kinds of data from NCBI eutils?
I have been researching NCBI eutils and wish to get some 'big data' from it. I know that I can construct queries to query one of (I think) 8 databases, like this:
...
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1answer
528 views
Maximum recombination frequency [duplicate]
During the process of crossing over, Why is the maximum possible recombination frequency between two genes equal to 50% and not more than that?
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0answers
81 views
The space of all human DNAs [closed]
This is both a math and biology question but I think it makes more sense for a biologist to answer it. My question is: what can be said, if anything, about the space of all possible human DNAs (for a ...
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0answers
27 views
Is Wikipedia a good source of taxonomy? [duplicate]
I have been quite interested in biology lately,and I would like to know whether it is a good choice to look up taxonomic information there.
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1answer
44 views
If DNA methylation inactivates genes, does DNA demethylation activate them?
DNA demethylation can be passive or active. The passive process takes place in the absence of methylation of newly synthesized DNA strands by DNMT1 during several replication rounds – for example, ...
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1answer
84 views
Possible combinations in the Meiosis' Telophase 1
As you might already know
Meiosis is the process in eukaryotic, sexually-reproducing animals that reduces the number of chromosomes in a cell before reproduction $^{[1]}$
One of the reasons why ...
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1answer
26 views
Repopullation after a mass extinction [duplicate]
Is it possible to restart the whole human species with less than 10 individual.
let say that the whole human species was wipe out of the surface of the earth by a catastrophe only 8 different couple ...
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1answer
43 views
What is the difference between Regulatory Gene and Modifier Gene?
If both controls the expression of another gene by physically or genetically interacting with the target gene, which attributes make "Regulatory gene" different from "Modifier gene" or vice-versa?
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The Viceroy Evolution Paradox [duplicate]
The viceroy butterfly generates a toxin compound which make it distasteful to predators. Biologists agree that the viceroy must have developed this trait as a passive defence mechanism to prevent ...
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2answers
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What was the biological mechanism that allowed Tarrare to eat so much?
Are there any conjectured mechanisms that cause Tarrare's extremely oversized stomach and abdominal cavity? Along with his superhuman appetite of course. Whether from a medical perspective or a ...
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1answer
42 views
Interpretation of genetic results
Result of genetic testing indicated: c.341del, p.Thr114Lysfs*37.
The c.341del probably means:deletion at the cDNA 341 nucleotide.
Buy what does the second part:p.Thr114Lysfs*37 ?
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0answers
157 views
what is the difference between homozygous and heterozygous duplication?
In a genetic test result it's written
homozygous duplication
or
heterozygous duplication
Does it mean four copies of the ...
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0answers
76 views
Does the law of independent assortment apply to homologous chromosomes or alleles, or both?
My textbook is giving me two definitions
1st def: "random orientation of homologous chromosomes at the metaphase plate in meiosis 1."
2nd def: "alleles for one gene separate into gametes ...
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1answer
64 views
How do biologists discover information from fossils? [closed]
I have a query about the study of fossils (palaeontology). Let me know about the study of fossils. How do biologist discover "DNA" information from dead and old fossils such as a dinosaur? (answer ...
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0answers
21 views
What are the issues with excessive tandem repeats in replication?
Why is it that tandem repeats like CAGCAGCAG cause primer-template misalignment and diseases like Huntingtons disease? By my understanding, too many such repeats can cause strands to form hairpins and ...
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1answer
202 views
Do all gene mutations in pathogens lead to more harmful consequences for humans?
It seems that the concern we always hear is that bacteria and viruses mutate to dodge our treatments either through random mutations or survival of the fittest. Do harmful living things ever mutate to ...
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1answer
98 views
Can I train my non-dominant hand and make it dominant?
Are our dominant limbs decided on birth or is there some way in which I can train my non-dominant hand and make it as coordinated as my dominant?
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1answer
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Is evolution theory falsifiable by whether mutations result in a loss or gain of genetic information? [closed]
If I understand the theory correctly, evolution revolves around the process of adaptation of a being to its environment which results in the increment of survival and reproduction chances for that ...
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1answer
39 views
What does Ercc1-/- / DAT-Cre+ mean?
I really need to know what Ercc1-/- / DAT-Cre+ mean. I think the 1st part means that the mice don't have the Ercc1 gene (knockout). But what about DAT-Cre+?
This question arised from reading the ...
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1answer
99 views
Why not self pollination for finding the genotype instead of test cross?
Test cross can tell us what's the genotype of a plant is. But we can know that even by self pollinating the plant. For example,
If a garden pea plant has the genotype TT, then self pollinating them ...
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1answer
40 views
How are mitochondrial diseases like MERRF inherited?
I am doing a project on the disorder MERRF in Mitochondrial DNA. I have to make a pedigree and explain how it is transferred on from generation to generation. I know that it is inherited maternally, ...
2
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0answers
60 views
What are the different types of SNPs?
When I search for this online I get answers such as substitutions, deletions, insertions etc. But I mean in the sense that I have been reading different terms infront of the word SNP such as: lead SNP,...
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1answer
55 views
How can inbreeding be used for selecting mutations?
I understand that inbreeding, after a number of generations of crossing genetically related individuals eventually yields homozygotes, however I can't seem to understand how it can be used for ...
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3answers
157 views
What makes an E.coli an E.coli, genotype or phenotype?
According to this paper, among 61 strains of E. coli they studied only 6% of the genes are common in all. Which means that the overwhelming majority of the genes are not shared.
And wikipedia ...
