Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

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Understanding genetic similarity in humans [duplicate]

I was reading "Blueprint" by Robert Plomin (online preview on webpage) and got stuck when I got to these two sentences in the prologue: "We are the same as every other human being for more than 99 ...
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x-linked recessive inheritance and correlation for males

I was inspired by a discussion in this thread. Wikipedia lists a number of disorders linked to recessive genes on the x-chromosome. One typical example is red-green color blindness. Now wikipedia says ...
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Maximum recombination frequency [duplicate]

During the process of crossing over, Why is the maximum possible recombination frequency between two genes equal to 50% and not more than that?
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Is Wikipedia a good source of taxonomy? [duplicate]

I have been quite interested in biology lately,and I would like to know whether it is a good choice to look up taxonomic information there.
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The Viceroy Evolution Paradox [duplicate]

The viceroy butterfly generates a toxin compound which make it distasteful to predators. Biologists agree that the viceroy must have developed this trait as a passive defence mechanism to prevent ...
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What are the issues with excessive tandem repeats in replication?

Why is it that tandem repeats like CAGCAGCAG cause primer-template misalignment and diseases like Huntingtons disease? By my understanding, too many such repeats can cause strands to form hairpins and ...
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How can inbreeding be used for selecting mutations?

I understand that inbreeding, after a number of generations of crossing genetically related individuals eventually yields homozygotes, however I can't seem to understand how it can be used for ...
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Can environmental pressures affect genes in one generation? [duplicate]

Environmental pressures are the catalyst of evolution. Pushing a species to adapt to changes therein. My question is can these mechanisms cause significant adaptation over one generation(parent-> ...
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Are there any DNA base sequences that are shared by every living being that we know of? And if yes, are some of those sequences “silent”?

In "every living being" I am not including viruses as another question already answered that. I have read that some part of the DNA sequences of humans and other animals/plants are "silent" as in not ...
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Convergence compared to genetic distance

Is there an information (preferably in the form of a chart, though anything will do) comparing convergent evolution to how closely related the 2 species are on the tree of life. My searches for ...
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113 views

How do these triplets code for these proteins?

I am slightly confused by the diagram above. The first codon of the unaltered DNA is AAG. During transcription, isn't this coverted to UUC (mRNA). So doesn't UUC code for phe and not Lys? Likewise, ...
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Fertilization of the human egg- where does our centrosome come from?

Is there a centrosome in a human egg cell? Is the reason why the egg cell remains paused before meiosis 2 because there isn't a centrosome, and it only divides when the sperm fertilizes it thus it can ...
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Why aren't “Water Giraffes” a thing?

If we assume that the Brachiosaurus and the modern Giraffe with their long necks both came to be by the need to reach higher-situated vegetable nutrition (which is a somewhat controversial assumption ...
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Does cellular/organism death happen to enable evolution? [duplicate]

On the topic of whether we could conceivably understand death and extend human lifespans significantly - I'm wondering if any smart folks can point me to where my thinking regarding death may be wonky....
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What metric(s) is a good proxy for relatedness?

In attempting to seed a simulation, where an individual foregoes resources that go r to same-type individuals and (1-r) to all members (including same-type individuals). What commonly used metrics ...
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132 views

epigenetic vs. environmental factors

I'm trying to understand the difference between epigenetic and environmental factors. For example, if gene A increases the risk of lung cancer by 50% and smoking increases the risk by another 75% when ...
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What are some features that do not make an individual better than others without this feature? [closed]

If a mutation occurs so that this allele gives a noticeable feature that is present in this individual but absent in every other individual and this feature is of no benefit or detriment to the ...
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Understanding Genetic Dynamics of Specific Problem

The following questions comes from International Biology Olympiad 2014, theoretical part B. It states: Earlier research suggested that the red flower pigment of plant species was the result of a ...
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DNA replication during Mitosis

I am a bit confused. During Meiosis, DNA is replicated to form a cell with half the DNA and likely to have variations. But since the replication process of meiosis and mitosis are the same, why do DNA ...
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222 views

How do you find probabilites of carrying an X linked recessive disease in a blank pedigree given only one phenotype?

In the above pedigree, the black square indicates the male affected with Hemophilia which is a X-linked recessive trait. What is the probability that the proposed child, which is a male (indicated as ?...
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103 views

Homework - Genetics linkage problem

A farmer purchases f1 hybrid seeds. These seeds contain four heterozygous loci that give a significant increase in crop yield when compared to either homozygote. Two of these loci are on the same ...
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134 views

How many Endogenous Retroviruses do we share with other primates?

Is there a list of Endogenous Retroviruses that we share with other primates? I would like to map all (or most) of them into a hierarchy and see how it fits in our evolutionary branch.
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Is the barcode COI sequence the sense or antisense strand of DNA?

Is the COI sequence commonly used for DNA barcoding the sense or the antisense strand of DNA?
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78 views

Why aren't there more Ash-Red pigeons?

My favorite color pigeon is Ash-Red, but I don't see a lot of them. I figured it must be a recessive phenotype, but when I googled it, I found out it's dominant. So why aren't there more Ash-Red ...
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Question about aneuploidy

I am learning about aneuploidy and non-disjunction and just wanted some clarification with regards to terminology. In particular, do the terms monosimony and trisimony refer only to INDIVIDUALS (i.e. ...
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Calculating gene separation -a genetics problem

I am really struggling with genetics. In particular, I have the following question Now I am OK with calculating the separation of genes in centrimorgans when I have data like so: But in the first ...
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Estimate of total number of oncogenic mutations

So there are a number of ways point mutations can hyperactivate or inactivate genes. But realistically there are only some small number of point mutations ever observed for a particular gene in ...
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DNA Sequencing and genotyping [closed]

Before going to the details of the question let me post a few other details- (I posted something similar and got no useful answers-probably because I didn't explain things properly or something else)- ...
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C to T Transition Mechanism

I am seeing C to T transitions in my sequencing data, but also some strange signatures that follow along with that. I am trying to understand the biology of what is occurring. In the data I see more C ...
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3answers
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Passing on Alleles

Just a basic question on alleles, I am just trying to learn the basic concepts. So if we are to screen two parents, both with one dominant and one recessive allele for a given characteristic e.g. eye ...
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Hybridization of an Indo-Aryan ethnic group and a Tibeto-Burmese ethnic group

The state in which I reside houses these two distinct ethnic groups. Physical Traits of the Indo-Aryan group Height:Medium Eyes:does not posses epicanthic fold Nasal bones:is not flat and broad ...
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Are antibiotic-resistant bacteria necessarily less virulent than their original strain?

In the absence of antibiotic treatment, is there a reduction in the average severity of disease caused by resistant strains of pathogenic bacteria compared to wild-type ones? I would assume that ...
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127 views

Is there an evolutionary advantage associated with migraine? [duplicate]

I have read Wikipedia article on Genetics of migraine headaches and I don't buy it Because genetics influence susceptibility to migraine, it can be shaped by evolution. Fitness-impairing ...
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Links between Genetics and Personality Types

This topic was visited briefly in the thread, Genetic Effects on Personality, but I was surprised not to find more on it. (Is there a taboo I don't know about? What's the ethical stance on this ...
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How do geneticists compute the percentage of DNA shared between species?

It's not exactly clear to me what is meant when people say that humans and bananas share 50% of their DNA.
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Is it possible for two creature in the same order and have odd haploid chromosome species to reproduce

Take the degu and the rat for example. The degu has 29 chromosome pairs Rats have 21 chromosome pairs. They are only share the same order ( Rodentia ) Would it be possible for them to reproduce? ( ...
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IBD-value in pedigree with inbreeding

I have a question about IBD. Please see the figure below. How many pairs of alleles are IBD for X and Y, or what is the IBD value for X and Y. Is it four (4)? I have seen it to be maximally 2, but ...
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689 views

Nature of Dengue Fever Genetic Material

Once the genetic material for Dengue Fever is inserted into the human DNA, would the Dengue Fever molecular material be in the form of its own isolated DNA fragment or will it be inserted directly ...
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Function and Mechanism of Height Genes

I have an inquiry regarding the exact function of height genes. To my knowledge, although they are heavily regulated by epigenetic factors, height genes can have either an "on" or an "off" allele, ...
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Cut-off values for LD, LOD and D-prime as algorithmic input

I created an algorithm to generate SNPs for random people of different descents - based on HapMap data. While this works good, there is something else I want to take into consideration. So if a SNP ...
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Similarity between the human genome and archea genome in deep sea hydrothermal vents?

I'm trying to find some reference that shows what percentage of the human genome is similar to some organism from the domain Archea that lives near or on deep sea hydrothermal vents. Can someone ...
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Genetic Relationship Matrix

The classical definition of the Genetic Matrix G = ZZ'/2p(1-p) where Z = M - P where P = 2(p-0.5) I don't have a background in biology but understand Maths and ...
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1answer
90 views

Solid mouse (C57BL/6) WT primers

I am trying to get a good pair (or better yet, library of pairs) of primers that give me one band in WT mice (C57BL/6). Do you know where I could find such a thing? Alternatively, I thought of just ...
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Barr body Giemsa staining

Not all the female cheek cells show Barr Bodies when stained with Giemsa stain? Only 30 to 40% female cells show Barr Bodies. Why? Our Experiment: We washed mouth twice with listerine to reduce ...
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Find the probability of Filium (child) that are dark (and) heterozygote [duplicate]

Two mice are crossed and both are dark and heterozygote. Find the probability of their filium(children) dark (and) heterozygote in F1. Here's what our teacher explained: I don't understand. I ...
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Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
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If gene differs between chromosome pair does individual get a mixture of protein shapes?

Do diploids such as humans end up with a mixture of two different shaped proteins where the appropriate gene is expressed differently in the two halves of a chromosome pair or is there some governing ...
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Phenotype choice for one of a MZ twin pair in a genetic association study

I was having a discussion with a colleague and this question came up... It is commonplace in molecular genetics studies to only genotype one of a pair of monozygotic twins (and then implicitly impute ...
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Can I train my non-dominant hand and make it dominant?

Are our dominant limbs decided on birth or is there some way in which I can train my non-dominant hand and make it as coordinated as my dominant?
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Is the lac operon repressed in the presence of both glucose and lactose?

In the presence of both sugars (glucose and lactose) will there be repression of the lac operon completely? I know that more glucose means less cAMP --> less CAP --> less positive regulation, and ...