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Questions tagged [hematology]

The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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How can a child be blood type AB, if both of the parents are blood type A?

Basically, both of my parents are blood type A (both are confirmed and it's also certain both of them are my biological parents). I recently found out my blood type is AB. How is this possible? I ...
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Can blood that has had an anticoagulant added to it be boiled without coagulating?

If I understood the information I've found elsewhere correctly, you can't boil untreated blood without it coagulating, right? But what if you added an anticoagulant to it? Would it be possible to boil ...
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43 views

What are the effects of oxygen toxicity in human blood?

I was reading some text on deep sea Physiology, and for to know that diving to do could cause oxygen toxicity in the blood. This was the exact text from the book Textbook of Medical Physiology by ...
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How could eating/drinking an alkaline substance change blood ph?

https://www.lifehacker.com.au/2016/12/no-foods-do-not-alter-the-ph-of-your-blood/ This article suggests that while the body maintains homeostasis through regulating ph via the kidneys, "High doses of ...
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How does extravasation of blood into surrounding tissues decrease blood loss?

Isn't that by itself, blood loss? (This is given as the 2nd step following vascular injury) ..or is there a way this blood is taken up or something?
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Has any work been done on using induced chimerism before birth to avoid tissue rejection?

See this question for a fuller description of the idea behind the question. I've only ever found one reference to this idea (in Xeno: The Promise of Transplanting Animal Organs into Humans By David K....
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19 views

In adverse effects of Heparin, why is bleeding from deeper organs more common?

The reason given in my book is that it i because it interferes with the secondary hemostasis..but i did not understand how that implies that bleeding from deeper organs is more common..
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What caused loss of conscious awareness (shutdown), tunnel vision, auditory exclusion, muscle sensation (explain physiology in detail)?

I am going to explain this situation I had a very strong fight or flight reaction towards someone who didn't pose any danger to me and I consciously knew he was no threat, I don't know him, never saw ...
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Could bone marrow transplants be used to prevent tissue rejection of trans-species organs?

So the immune system doesn't calibrate (for want of a better euphemism) to recognize it's own cells until fairly well along in fetal development & the major components of the immune system (...
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How do natural hearts deal with the risk of blood clots associated with artificial hearts, VADs, and valves

From what I read about artificial devices engineered to substitute parts of the heart or the entire heart, blood clotting is a major risk that can be modulated by the device's surface material and ...
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29 views

How does the cardiac cycle and electrical activity all relate to blood pressure in the heart? [closed]

I know how the cardiac cycle works and understand the electrical activity in the heart such as the AV nodes, SA nodes and Bundles, but how do they work together in relation to blood pressure?
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Does blood carry metallic nanoparticles?

I find this particular chart about constituents of blood very informative and interesting. Looking through the different components, I see metals such as copper, zinc, etc. Are these only carried as ...
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47 views

How does vasodilation slow blood flow?

During inflammation, cytokines and histamine cause vasodilation to increase blood flow to the inflamed area. However, it is also said that vasodilation slows blood flow which facilitates the adhesion ...
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Realistic Application of CRISPR in Human Disorders

Human trials recently began to use the genome editing technology CRISPR to treat sickle cell anemia using edited stem cells. Sickle cell anemia is caused by a single DNA Mutation, and is also a ...
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Can a cancerous cell from outside cause cancer in a healthy person?

If a cancerous cell enters the body of a healthy person from someone else's blood or something, will that healthy person get cancer? In human beings.
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Why is there low hepcidin levels in hemochromatosis?

If hemochromatosis is iron overload and there is excess iron in the blood, why does the liver reduce hepcidin secretion (which increases the iron uptake) furthering the worsening of hemochromatosis?
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What's the difference between a lymphocyte and a plasma cell?

According to my understanding, lymphocytes is the broad terminology for both T lymphocytes as well as B lymphocytes, while plasma cells refers to mature B cells which produce antibodies. But then why ...
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Why is beta thalassemia major not lethal while alpha thalassemia with loss of all 4 genes lethal?

So why is beta thalassemia major with two B0 alleles not fatal in utero (despite the hemoglobin not having any B chains), while alpha thalassemia with deletion of all 4 genes encoding for the alpha ...
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What's the difference between beta thalassemia minor and beta thalassemia intermediate?

I mean beta thalassemia minor is caused by inserting one abnormal allele while beta thalassemia intermediate is when the person has at least one B+ allele. Is beta thalassemia intermedia a type of ...
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Why do I feel nauseous at the sight of blood, despite not being afraid of it?

Every time I ask google this question, all it spits at me is info on blood phobias ^-^; basically, I've always been hugely interested in morbid stuff, but I noticed that I always feel sick when ...
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131 views

How does a glucose molecule enter the cell from blood vessel?

The transporters in the plasma membrane of the cells promote the entry of glucose molecules from the extracellular matrix to the cytosol of the cell. Could someone explain how does the nutrient ...
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why is erythrocyte sedimentation rate higher in females?

erythocyte sedimentation rate should be independent of the sex. what is the reason behind this sex bias and why does it increase during pregnancy and how does age influence it.
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Is too much CO2 in the air toxic?

I know that if there is too much CO2 in the air we will have too much greenhouse effect. I would like to know if there is too much CO2 in the room, something like 3% while there is also more that ...
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Why should collected blood from patients be analyzed as soon as possible?

I'm looking for the possible factors influencing blood samples. What happens to the blood cells esp. WBCs/PBMCs after 8 hours of blood draw? For example, I know that granulocytes may cause oxidative ...
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What would the RBCs of someone heterozygous for sickle cell anemia look like?

Would half of the RBCs look normal, and the other half sickled? Or would all of the RBCs have slight deformation/sickling? Thanks!
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Is there a specific suffix for “within a cell”? i.e. in a similar manner to how -aemia refers to within the blood

Words like hyperglycemia and hyponatremia refer to the relative level of each component in the blood, not in the cell. Is there a suffix for within the cell? For reference I would like one word as an ...
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104 views

Why does applying pressure to a venipuncture site prevent haematoma?

From what understand, when drawing blood, a phlebotomist puts pressure on the venipuncture site while withdrawing the needle to prevent a haematoma. I'd like clarification; How does this prevent a ...
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41 views

Turbulence in blood

Turbulence in blood flow is known to indicate diseased or obstructed arteries. Techniques to measure turbulence in blood flow are mostly based on turbulence kinetic energy measurments using MRI [e.g., ...
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Is it okay to donate blood after doing miRNA extractions?

I am planning to do miRNA extraction from the blood serum using Qiagen miRNeasy Serum/Plasma kit. As I am frequently participating in the whole blood donation (not for experiment; the process ...
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104 views

Found in blood sample - what is it? Hopefully not a nemotode-

After examining someone's blood - through microscope - I found these. There were some more that were not photographed. Could someone please inform me on what these are? Maybe abiotic material on the ...
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In Vivo and In Vitro Assays for Determining Self-Renewal Capabilities of of HSC and Progenitor Cells?

I am interested in understanding how we can determine the self-renewal capabilities of different cells on the hematopoietic hierarchy. For example, lets say I have a purified subset of MPP cells. How ...
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How does blood react to heat when inside the body

I was wondering: What are the possible dangers of being burned on the surface of the skin. Does it congeal (that's what my intuition tells me)? At which temperature would that happen? How heat-...
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How do drugs tests check so many substances?

There are about 170 drugs banned for sports and many other drugs that can be used in crimes. How can blood tests practically detect so many different substances? Do they divide the sample into 170 ...
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Location of ABO and Rh antigens

I read somewhere that in addition to red blood cells (RBCs), ABO antigens can be found in the other body tissues of the human. But Rh antigens located just on RBCs, in the other words, Rh polypeptides ...
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862 views

Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

Erythrocytes (red blood cells) are a common feature of almost all vertebrates. What evolutionary advantage do they provide in containing haemoglobin, rather than it being just a plasma protein? In ...
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Mice that have been reconstituted with geneX-transduced cells

I read this article in the following: ... Mice that have been reconstituted with geneX-transduced cells Now, someone who is not familiar with animal sciences, what does this exactly mean? ...
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Why does Anti-A antibodies make type-A blood type clump?

A-type blood has B-antibodies; it also clumps anti-A antibodies are inserted. Why is that? The blood has no antibodies against the A-antibodies to make clump in this way.
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How might IV-saline cause kidney damage that seems to be less likely with “balanced fluids” IVs instead?

The ABC News article What's in the IV bag? Studies show safer option than saline includes: Saline — salt dissolved in water — has been the most widely used fluid in the U.S. for more than a century ...
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If women need more dietary iron than men, then do blood donors also?

My understanding that women's dietary iron requirements are slightly higher because I've heard the only way of losing iron from your body is by losing blood, and this happens in menstruation. This got ...
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What are these flower like cells in the photo attached?

I am a student of BSc. Zoology... I was doing a TC of RBC of my blood when I encountered these strange flower like cells. Are they lysed RBCs ? If so, why are they so geometric in shape ?
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Is carbon dioxide dissolved in plasma same as carbonic acid?

Carbon dioxide is transported through blood via 3 methods : 1. Dissolved in plasma 2. As bicarbonate ion 3.through RBCs. The carbondioxide when transported as bicarbonate ion i.e HCO3- and H+. What ...
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Sickle cell life span

How long do sickle red blood cells "live" before being broken down in phagocytosis? I had trouble doing a normal search as it brings up life span of those inflicted with the disease. Also, I have ...
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Do Marsupials have a standard classification system for their blood groups?

I've seen a limited amount of animal blood groups listed...like dogs, cats, horses, etc. But what blood types do marsupials have? To clarify, what I want to know is if the species has a ...
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202 views

Why is blood collected at crime scenes? [closed]

I have read that mature red blood cells (MRBs)do not have DNA. So I am curious why crime scene technicians collect blood. Is it to collect and amplify segments of white blood cells?
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What happens to neutrophils in whole blood stored for transfusion?

The lifetime of neutrophils is normally quite short, 3-5 days in vivo (link). On the other hand, whole blood can be stored for a fairly long time, up to 35 days (link). What happens to neutrophils ...
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1answer
255 views

Veins collapse when empty

Veins collapse when empty. That's because they have thin and almost inelastic walls. What has inelasticity and thinness of the walls to do with the collapsing of the veins?
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Does donating blood lower testosterone levels? [closed]

I'm a guy and I decided to donate blood because of persuasion. My testicles feel weak afterwards specifically. I mean they feel like they're compensating -- assuming that makes sense. Is this because ...
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1answer
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What are null cells?

My histology textbook says the following: The pluripotential hemopoietic stemm cell (which resembles a lymphocyte) is a member of the null cell population of lymphocytes. It then goes on to add: ...
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Why do erythrocytes have no MHC1 but platelets do?

Red blood cells do not have a considerable number of MHC1 through their membranes, and that's explained by them not having a nucleus. But why do platelets have MHC1s if they have no nucleus either? I ...
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66 views

Blood Group Notation

In a textbook, I encountered a notation used when writing blood groups down, which was "I" with the blood group type as a superscript. I was curious as to why the letter "I" is used in this notation ...