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Questions tagged [hematology]

The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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+100

Can a person survive on blood in place of water?

This question: Can you get enough water by eating only fish? asks if a person could survive on fish alone. Can a person survive on fish and/ or blood alone of any species if stuck at sea or animal ...
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How are codocytes or target cells formed?

How are codocytes or target cells formed in conditions like Thalassemia? And why do they appear like a target(as in why is there a central red surrounded by pallor surrounded by red?)
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1answer
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How does blood pressure substantially drop in the capillaries and arterioles?

Is this due to increased frictional resistance which decreases the velocity of the blood? You would think using Bernoulli's principle that the velocity of blood in the capillaries would increase due ...
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1answer
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When endothelial cells in blood vessels (arteries or veins) are damaged, does atheroma form first or blood clot?

I have learnt from Khan Academy's video on atheresclerosis that when the endothelial cells of an artery are damaged, atheroma forms at the site, and if the atheroma’s fibrous cap is ruptured, ...
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1answer
41 views

How do veins's valve pocket sinus tend to become hypoxic?

For context, this question relates to the formation of deep vein thrombosis as I read that hypoxemia in vein can trigger coagulation cascade and cause a thrombus to form in vein. I read that vein's ...
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0answers
35 views

Is there other unknown-compound in Blood?

Blood is made of red blood cells, platelets, plasma etc. Let's say, then, there are these $x$ known compounds in blood. But how can one be sure that there is no other compound other than those $x$ ...
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Are there health benefits to donating blood?

Donating blood is typically thought of as a commensal act, benefiting the recipient at no cost beyond time and inconvenience to the donor. Some even view it as a parasitic act, wherein the recipient ...
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1answer
33 views

Why does atheroma contain thromplastin/tissue factor?

From my understanding, when the endothelial lining of arteries is damaged, atheroma is formed at the site of the damaged area. If the atheromas is ruptured, thromboplastin contained in atheroma is ...
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26 views

What is the role of plasminogen used in the preparation of APSAC? (Anisoylated Plasminogen Streptokinase Activator Complex)

What is the role of plasminogen in APSAC, and how is there indirect activation of plasmin through APSAC? Reference https://www.sciencedirect.com/topics/chemistry/fibrinolytic-agent
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1answer
83 views

Lobed Nuclei still count as One nucleus?

Do the Lobed Nuclei of immune cells (such as Megakaryocytes) still count as one nucleus?
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1answer
52 views

Where do Red Blood Cells use energy?

I know that RBCs use glycolysis of glucose to lactate to produce most of their energy, but, if they are just carrier cells, where do they use the energy?
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140 views

How can a child be blood type AB, if both of the parents are blood type A?

Basically, both of my parents are blood type A (both are confirmed and it's also certain both of them are my biological parents). I recently found out my blood type is AB. How is this possible? I ...
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1answer
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Can blood that has had an anticoagulant added to it be boiled without coagulating?

If I understood the information I've found elsewhere correctly, you can't boil untreated blood without it coagulating, right? But what if you added an anticoagulant to it? Would it be possible to boil ...
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1answer
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What are the effects of oxygen toxicity in human blood?

I was reading some text on deep sea Physiology, and for to know that diving to do could cause oxygen toxicity in the blood. This was the exact text from the book Textbook of Medical Physiology by ...
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1answer
36 views

In adverse effects of Heparin, why is bleeding from deeper organs more common?

The reason given in my book is that it i because it interferes with the secondary hemostasis..but i did not understand how that implies that bleeding from deeper organs is more common..
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1answer
783 views

Could bone marrow transplants be used to prevent tissue rejection of trans-species organs?

So the immune system doesn't calibrate (for want of a better euphemism) to recognize it's own cells until fairly well along in fetal development & the major components of the immune system (...
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1answer
126 views

How does the cardiac cycle and electrical activity all relate to blood pressure in the heart? [closed]

I know how the cardiac cycle works and understand the electrical activity in the heart such as the AV nodes, SA nodes and Bundles, but how do they work together in relation to blood pressure?
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1answer
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Does blood carry metallic nanoparticles?

I find this particular chart about constituents of blood very informative and interesting. Looking through the different components, I see metals such as copper, zinc, etc. Are these only carried as ...
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1answer
70 views

How does vasodilation slow blood flow?

During inflammation, cytokines and histamine cause vasodilation to increase blood flow to the inflamed area. However, it is also said that vasodilation slows blood flow which facilitates the adhesion ...
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0answers
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Realistic Application of CRISPR in Human Disorders

Human trials recently began to use the genome editing technology CRISPR to treat sickle cell anemia using edited stem cells. Sickle cell anemia is caused by a single DNA Mutation, and is also a ...
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3answers
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Can a cancerous cell from outside cause cancer in a healthy person?

If a cancerous cell enters the body of a healthy person from someone else's blood or something, will that healthy person get cancer? In human beings.
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1answer
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Why is there low hepcidin levels in hemochromatosis?

If hemochromatosis is iron overload and there is excess iron in the blood, why does the liver reduce hepcidin secretion (which increases the iron uptake) furthering the worsening of hemochromatosis?
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0answers
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What's the difference between a lymphocyte and a plasma cell?

According to my understanding, lymphocytes is the broad terminology for both T lymphocytes as well as B lymphocytes, while plasma cells refers to mature B cells which produce antibodies. But then why ...
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2answers
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Why is beta thalassemia major not lethal while alpha thalassemia with loss of all 4 genes lethal?

So why is beta thalassemia major with two B0 alleles not fatal in utero (despite the hemoglobin not having any B chains), while alpha thalassemia with deletion of all 4 genes encoding for the alpha ...
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0answers
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Why do I feel nauseous at the sight of blood, despite not being afraid of it?

Every time I ask google this question, all it spits at me is info on blood phobias ^-^; basically, I've always been hugely interested in morbid stuff, but I noticed that I always feel sick when ...
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1answer
256 views

How does a glucose molecule enter the cell from blood vessel?

The transporters in the plasma membrane of the cells promote the entry of glucose molecules from the extracellular matrix to the cytosol of the cell. Could someone explain how does the nutrient ...
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why is erythrocyte sedimentation rate higher in females?

erythocyte sedimentation rate should be independent of the sex. what is the reason behind this sex bias and why does it increase during pregnancy and how does age influence it.
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Is too much CO2 in the air toxic?

I know that if there is too much CO2 in the air we will have too much greenhouse effect. I would like to know if there is too much CO2 in the room, something like 3% while there is also more that ...
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1answer
45 views

Why should collected blood from patients be analyzed as soon as possible?

I'm looking for the possible factors influencing blood samples. What happens to the blood cells esp. WBCs/PBMCs after 8 hours of blood draw? For example, I know that granulocytes may cause oxidative ...
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1answer
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What would the RBCs of someone heterozygous for sickle cell anemia look like?

Would half of the RBCs look normal, and the other half sickled? Or would all of the RBCs have slight deformation/sickling? Thanks!
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1answer
178 views

Is there a specific suffix for “within a cell”? i.e. in a similar manner to how -aemia refers to within the blood

Words like hyperglycemia and hyponatremia refer to the relative level of each component in the blood, not in the cell. Is there a suffix for within the cell? For reference I would like one word as an ...
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1answer
276 views

Why does applying pressure to a venipuncture site prevent haematoma?

From what understand, when drawing blood, a phlebotomist puts pressure on the venipuncture site while withdrawing the needle to prevent a haematoma. I'd like clarification; How does this prevent a ...
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1answer
56 views

Turbulence in blood

Turbulence in blood flow is known to indicate diseased or obstructed arteries. Techniques to measure turbulence in blood flow are mostly based on turbulence kinetic energy measurments using MRI [e.g., ...
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Found in blood sample - what is it? Hopefully not a nemotode-

After examining someone's blood - through microscope - I found these. There were some more that were not photographed. Could someone please inform me on what these are? Maybe abiotic material on the ...
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In Vivo and In Vitro Assays for Determining Self-Renewal Capabilities of of HSC and Progenitor Cells?

I am interested in understanding how we can determine the self-renewal capabilities of different cells on the hematopoietic hierarchy. For example, lets say I have a purified subset of MPP cells. How ...
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How does blood react to heat when inside the body

I was wondering: What are the possible dangers of being burned on the surface of the skin. Does it congeal (that's what my intuition tells me)? At which temperature would that happen? How heat-...
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1answer
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How do drugs tests check so many substances?

There are about 170 drugs banned for sports and many other drugs that can be used in crimes. How can blood tests practically detect so many different substances? Do they divide the sample into 170 ...
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0answers
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Location of ABO and Rh antigens

I read somewhere that in addition to red blood cells (RBCs), ABO antigens can be found in the other body tissues of the human. But Rh antigens located just on RBCs, in the other words, Rh polypeptides ...
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Why isn’t Haemoglobin a plasma protein, rather than being encompassed by the erythrocyte?

Erythrocytes (red blood cells) are a common feature of almost all vertebrates. What evolutionary advantage do they provide in containing haemoglobin, rather than it being just a plasma protein? In ...
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1answer
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Mice that have been reconstituted with geneX-transduced cells

I read this article in the following: ... Mice that have been reconstituted with geneX-transduced cells Now, someone who is not familiar with animal sciences, what does this exactly mean? ...
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Why does Anti-A antibodies make type-A blood type clump?

A-type blood has B-antibodies; it also clumps anti-A antibodies are inserted. Why is that? The blood has no antibodies against the A-antibodies to make clump in this way.
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1answer
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How might IV-saline cause kidney damage that seems to be less likely with “balanced fluids” IVs instead?

The ABC News article What's in the IV bag? Studies show safer option than saline includes: Saline — salt dissolved in water — has been the most widely used fluid in the U.S. for more than a century ...
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1answer
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If women need more dietary iron than men, then do blood donors also?

My understanding that women's dietary iron requirements are slightly higher because I've heard the only way of losing iron from your body is by losing blood, and this happens in menstruation. This got ...
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0answers
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What are these flower like cells in the photo attached?

I am a student of BSc. Zoology... I was doing a TC of RBC of my blood when I encountered these strange flower like cells. Are they lysed RBCs ? If so, why are they so geometric in shape ?
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Is carbon dioxide dissolved in plasma same as carbonic acid?

Carbon dioxide is transported through blood via 3 methods : 1. Dissolved in plasma 2. As bicarbonate ion 3.through RBCs. The carbondioxide when transported as bicarbonate ion i.e HCO3- and H+. What ...
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1answer
1k views

Sickle cell life span

How long do sickle red blood cells "live" before being broken down in phagocytosis? I had trouble doing a normal search as it brings up life span of those inflicted with the disease. Also, I have ...
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0answers
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Do Marsupials have a standard classification system for their blood groups?

I've seen a limited amount of animal blood groups listed...like dogs, cats, horses, etc. But what blood types do marsupials have? To clarify, what I want to know is if the species has a ...
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1answer
247 views

Why is blood collected at crime scenes? [closed]

I have read that mature red blood cells (MRBs)do not have DNA. So I am curious why crime scene technicians collect blood. Is it to collect and amplify segments of white blood cells?
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What happens to neutrophils in whole blood stored for transfusion?

The lifetime of neutrophils is normally quite short, 3-5 days in vivo (link). On the other hand, whole blood can be stored for a fairly long time, up to 35 days (link). What happens to neutrophils ...
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1answer
365 views

Veins collapse when empty

Veins collapse when empty. That's because they have thin and almost inelastic walls. What has inelasticity and thinness of the walls to do with the collapsing of the veins?