Questions tagged [hematology]

The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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Do people with type O- blood have a higher risk for autoimmune diseases?

Recently in my Physiology class, I learned that antigens help the immune system differentiate between the body's own cells and foreign cells. This led me to this question: If people with type O- blood,...
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What exactly does my body do with oxygen? Why do I need it? [closed]

I know that my body and brain need oxygen in order to survive. If I stop breathing, my lungs (and blood) can't distribute oxygen to my body anymore, and I could get brain damage and die. What exactly ...
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Is Haemoglobin a positively charged Sol?

My book NCERT(Class 12, Surface chemistry) claims that hemoglobin is a positively charged sol The cytosolic pH in human cells is around 7.4, but fluctuates as the cell is replicating according to ...
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Why are basophils and eosinophils considered granulocytes?

I have read that granulocytes are a type of leukocytes that have granules (hence the name) visible by microscopy. But then there is something called a granulocyte/monocyte progenitor cell, which I ...
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Why is heparin contraindicated in patients with severe uncontrolled hypertension?

Heparin is a parenteral anti coagulant- prevents clot formation by inhibiting factors 2 a and 10 a mainly. Now, patients with severe uncontrolled hypertension- have persistent bp of more than 140/90. ...
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Vitamin B12 deficiency Megaloblastic anemic

I have two doubts regarding Megaloblastic anemia which shakes my mind (1) first is- I know that vitamin B12 is required for thymidine synthesis which is further required for DNA synthesis and so if ...
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How does the negative charge on endothelium prevent blood coagulation?

I was reading about the factors that keep the blood inside the body in fluid state and came across a line in my book which states that, "Smoothness of the endothelium, its negative charge and its ...
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What is the time frame for coagulation of blood cells & the resulting separation of the cells and platelets from the plasma in a dead body?

I have had this subject come up repeatedly in the context of a discussion about death and how it affects the body. I found this statement, which is typical of the common understanding among non-...
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Why is only the donor's antigen seen during a blood transfusion?

I am a high school student and I am a little confused that why only donor's antigen matters during blood transfusion? for e.g if the donor's blood is O- so it means that it will antibodies against all ...
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What is the water content of avian blood?

I'm doing a work about heavy metal contamination in seabirds. I have found that the toxic threshold for Cu in blood is 1,15 μg/g wet weight. That number refers to an average between some seabirds. I ...
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What is the relationship between the oxygen affinity of hemoglobin and the maximal oxygen uptake (VO₂ max) of the human body?

I was curious about whether any of the numerous documented human hemoglobin variants conferred a quantifiable athletic advantage but the only thing I've found of any relevance is the relative oxygen ...
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Blood cell lineages

Blood cells are often spoken of as arising from three lineages -- erythroid, myeloid, and lymphoid lineages that will respectively produce the red cells; the platelets, granulocytes, and monocytes; ...
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Why don’t bone marrow donations harm the donor in the long term?

I have googled about this, and the most I can really find is that donating bone marrow/blood stem cells is not harmful in the long run, but I want to know why and how much is really known about this. ...
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Why are cells in blood smears undetectable after absorbing moisture?

I'm a student learning how to prepare blood films and today I was curious about something, so I performed an experiment. After preparing a thin blood smear and drying it (no staining), I took a look ...
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What are these structures in blood from a nosebleed?

I decided to look at some blood from a nosebleed (not mine) under the microscope and took some pictures of the results. There many large orange structures interspersed within the blood cells and I'm ...
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Can a person survive without platlets in the bloodstream? [closed]

Can a person survive without platlets or thrombocytes in the bloodstream, if I guarentee that the person is isolated and won't injure? Any help will be appreciated. Thank you!
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Does alcohol really helps to get substances get faster into the bloodstream? [closed]

I saw the video where Arnold Schwarzenegger cooks some protein cocktail and adds Austrian Schnapps to the mix, saying that it's to make everything get faster to the blood. Is it true or some kind of a ...
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is blood anaerobic? [closed]

I was wondering if anyone knows whether there is free molecular oxygen in the blood? My reasoning would be that oxygen is too reactive to be left alone in the blood, that's why it is transported in a ...
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Uranium based blood [closed]

Here's a hypothetical planet with complex, sapient life and a very weak magnetic field. Could they have Uranium-based blood, much as our blood is based on iron and crab's is based on copper? ...
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How long does foreign DNA stay intact in human blood?

How aggressively is foreign DNA in blood targeted and degraded by the human body? I am asking because we have a metagenomics project where we want to detect parasite DNA in the human blood. The ...
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How good are the hematologic parameters (e,g, IL6 or others) in predicting which patients will develop a severe COVID-19 disease?

Clinical implications of the hematologic profile of COVID-19 patients including cytokine storm, coagulation profile and thrombophilic complications are starting to be recognized. Hypercoagulability ...
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How do injected purified anti-D antibodies prevent the natural production of antibodies in order to prevent Hemolytic Disease of the Newborn?

Treatments involving Anti-D antibodies are given to pregnant women carrying Rh+ fetuses when the mother has an Rh- blood type in order to prevent Hemolytic Disease of the Newborn during the 2nd ...
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Blood serum transfusions - could vaccines against the anti-A/anti-B etc. antibodies be derived, at least in theory?

People with the AB-positive blood type have all three of the A, B and RhD antigens present on their red blood cells, and no antibodies to these in their blood serum (aka blood plasma.) This means that ...
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What is the mechanism of aspirin as an anticoagulant? [duplicate]

I understand that aspirin prevents blood clots from forming by interfering with the clotting action. I want to know at which stage aspirin interferes with clot forming and what really happens in the ...
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CML (Chronic Myeloid Leukemia) and blast cell percentage

I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
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If you add type A blood to type B blood, is there a visible reaction?

I read that the original discovery of blood types was because they combined random blood samples togethers and noticed a reaction. I was wondering if this was a visible reaction? Or is anti-A or anti-...
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Why is the blood thick in Wet Cupping / Hijama

I have just witnessed the wet cupping procedure being performed and have questions regarding the blood that is seen in the cups. I understand there are no studies that show cupping is an effective ...
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How many hematopeietic stem cells (in percentage) does the bone marrow contains?

I've found out that the body marrow of an adult weights about 5% of it's total weight. How much (%) of the bone marrow consists of hematopeietic stem cells and how much consists of other non-...
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How far up a limb can a severed artery retract?

This is about the application of tourniquets. I was taught a hand width above wound, but recently I read severd arteries can in some cases retract higher than that which would then bleed into the arm. ...
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What is the mass of a single erythrocyte?

I really have been searching through internet on different languages, but can’t find any article that answers on the question what is the single erythrocyte mass. I don’t know, I think it’s pretty ...
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What is blood pH for different animals?

So we all know that humans average blood pH is 7.4. But is it the same for the animals? I need examples of animals with the same blood pH as humans and the ones with different blood pH. I guess dogs ...
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How does the choice of blood draw site influence the possible specificity of a serological test?

The news has reported that a new serological test for the presence of anti-SARS-CoV-2 antibodies has received an emergency use authorization from the FDA, and notably has a higher specificity than ...
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Edema and hydrostatic pressure

I'm currently studying Robbins basic pathology, and I'm confused about a specific statement: It states in the book that when hydrostatic pressure is low due to a lack of albumin synthesis, it leads ...
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What causes the localization of myoglobin in turkey to regions of muscle tissue?

I've read that myoglobin localization is responsible for the darker colour of leg muscles in turkeys. Why does this localization occur in terms of any of cell biology, molecular biology, or ...
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Can erythrocytes Function without plasma?

my title is not very specific. So i will proceed to clarify it. I am trying to make sure that the only blood cells in a sample are Erytocytes, since i want to evaluate their metabolism, I am aware ...
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Is there any situation where bloodletting should be paired with transfusion?

Clearly, bloodletting only has benefits in a couple of rare instances —— for example promoting blood flow into reattached tissues1. But could it (or, should it) realistically be used along with ...
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Pressure measurement blood flow

During blood pressure measurement, when the flow within the arteries of the arm is interrupted, how is blood flow redistributed to the rest of the circulatory system? Is it possible that more blood ...
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Which type of test tube should not be used for blood collection?

The following question is presented in my biology textbook: You are required to draw blood from patient and keep it in a test tube for analysis of blood corpuscles and plasma. You are provided with ...
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How much heme is in cooked pork and beef; why is cooked pork ("the other white meat") not red?

The new video See how Impossible Pork will make you forget about pig meat includes a very short discussion of the addition of heme to the product to make it taste like beef the deep red color of a ...
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How is plasmin formed from plasminogen?

In Ganong's Review of medical physiology it is mentioned that plasminogen is converted to active plasmin when tissue type plaminogen activator hydrolyses the bond between Arg560 and Valine 561. Can ...
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Would gargling with salt water every day increase blood sodium levels?

Would gargling and rinsing with salt water every day for a few minutes increase your blood sodium levels? Considering the fact that sublingual medication is a very effective way for introducing ...
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Does animal blood, esp. human, really have similar salinity as ocean water, and does that prove anything about evolution?

It is an often-repeated claim that human, and in fact all animal blood is salty because we evolved from aquatic organisms, and that blood has a similar concentration of salts as ocean water, or at ...
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Where can I find extensive information on animal blood types and transfusions?

I'm interested in doing research on different animal blood types, including blood transfusion across different species. What are some resources you could recommend for me?
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How much does capillary action contribute to blood flow to the human brain?

The BBC News Universal Wonders short video Why water is one of the weirdest things in the universe says after 01:50: Water molecules can float upwards against the ...
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Non-nucleated cell-like population with RNA

We're working on invertebrate hemolymph (blood) and we have found with flow cytometry (staining with DRAQ5) a cell-like population without nucleus but it has RNA production. Does anyone any ...
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Why are red blood cells not attacked by NK cells?

All cells containing a nucleus present MHC-I, while some specialized cells present MHC-II in addition to that. Since erythrocytes lack any MHC why do natural killer cells not attack them? It is my ...
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How are monocytes larger than capillaries?

I have read that the average size of a capillary is about 8 micrometers. How is it possible that the 15 micrometer or so monocytes in blood do not block these vessels? https://en.m.wikipedia.org/wiki/...
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Can a person survive on blood in place of water?

This question: Can you get enough water by eating only fish? asks if a person could survive on fish alone. Can a person survive on fish and/ or blood alone of any species if stuck at sea or animal ...
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How does blood pressure substantially drop in the capillaries and arterioles?

Is this due to increased frictional resistance which decreases the velocity of the blood? You would think using Bernoulli's principle that the velocity of blood in the capillaries would increase due ...
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When endothelial cells in blood vessels (arteries or veins) are damaged, does atheroma form first or blood clot?

I have learnt from Khan Academy's video on atheresclerosis that when the endothelial cells of an artery are damaged, atheroma forms at the site, and if the atheroma’s fibrous cap is ruptured, ...

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