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Questions tagged [hematology]

The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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1answer
84 views

Triosephosphate isomerase deficiency

Triose phosphate isomerase deficiency, a rare condition, is the only glycolytic enzymopathy that is lethal. This deficiency is characterized by severe hemolytic anemia and neurodegeneration. How can ...
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1answer
652 views

Effect of forced breathing on RBC size

Microcytosis, i.e. decrease in the size of RBCs occurs: – In iron deficiency anaemia, – During prolonged forced breathing and – When osmotic pressure of the blood is increased. I am ...
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2answers
26k views

What percent of your blood can you lose before you need a transfusion

Losing a little blood is okay. If your a normal healthy person, and got into an accident, how do they know if you need a transfusion or if you'll be okay? This is hypothetical.
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2answers
987 views

Why does high EDTA concentration cause swelling of platelets?

According to this textbook, high ( >2mg/ml of blood) EDTA concentration causes swelling of platelets which lead to their fragmentation. I know that high concentration of EDTA increases plasma ...
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3answers
15k views

Presence of MHC on red blood cells

Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
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1answer
1k views

How is the probability of Rh type inheritance calculated?

I found somewhere on the Internet that, if parents are both Rh-positive, their children have 93.75% chance of being RH-positive and 6.25% chance of being RH-negative. My question is: How is this ...
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1answer
221 views

Roughly at least, how many types of cells comprise human blood?

A long time ago there were only three kinds - red, white, and rose platelets. Advances in cell sorters and more recently in genetic techniques and differentiation studies have led to the ...
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1answer
518 views

Human anti animal antibodies issues in blood testing

Do people have to be exposed to animals to get HAMA antibodies? Can these antibodies impact blood tests with false negatives as well as false positives?
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0answers
101 views

What does factor VIII have to do with thromboplastin formation?

I've got the following question and I'm afraid that the question doesn't match with the answer... Factor III (rather than factor VIII) is known as thromboplastin or tissue factor and it makes sense ...
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1answer
494 views

Why does ammonium oxalate cause swelling of RBCs?

From Pre examination procedures in laboratory diagnosis by Walter Guder : ...It consists of three parts by weight of ammonium oxalate which causes swelling of erythrocytes balanced by two parts ...
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1answer
44 views

Arteries used for inserting catheter

For catheter purpose, femoral and subclavian arteries are mostly used as starting point. Why? Are there other arteries which are used for the purpose?
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0answers
96 views

Is human blood useful as food?

Lacking other resources, could a healthy adult slit his wrist to feed a starving child with his blood? Would it be nutritional and would a starving dehydrated child eat it?
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What are preparation mistakes that could make red blood cells appear crenate in isotonic solution?

Thank you for your time. I separated red blood cells from a whole blood sample purchased from a blood bank. In isotonic solution, the red cells appear crenate. I would like to know if there is ...
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2answers
1k views

Can one use a hemocytometer on a compound upright microscope?

I'm posting this as a follow-up on What to look for when buying a light microscope?. The answerer states that you would need to use a an inverted microscope to count cell in the hemocytometer(counting ...
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1answer
150 views

How does one experimentally obtain a hemoglobin-oxygen dissociation curve?

I've always wanted to do comparative eco-physiology studies looking at Hemoglobin-Oxygen affinity of populations in different environments, but I can't find a protocol to experimentally measure the ...
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1answer
2k views

Can you bleed from your bones?

I was talking to my science teacher about the body specifically the red bone marrow. She said that blood is created in the red bone marrow. Does that mean that if you were to cut a fresh bone open ...
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2answers
155 views

Are there any exceptional cases in which a person with O negative blood group cannot donate?

Are there any exceptional cases in which a person with O negative blood group cannot donate or any case in which compatibility might not be established between O negative an any other blood group?
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1answer
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Hemoglobin oxygen affinity curve

I have a general understanding of the Bohr effect, and that Hemoglobin's affinity for oxygen will shift depending on the conditions of the lungs and tissues. However, I'm struggling with the following ...
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0answers
57 views

What could be the reason for the large difference between sodium and potassium blood concentrations?

Reference values for sodium and potassium concentrations in blood tests are usually in the range of 135-145 mEq/L and 3.5-5.1 mEq/L, respectively. My question is what could be the reason for this (...
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0answers
4k views

Chart of blood pH across different animal species?

How does blood pH vary across species? I can't find an article or chart listing this kind of information. So far I've found bits and pieces like: Human blood pH is nominally 7.4. 7.4 seems to be a ...
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1answer
147 views

Reusing frozen blood [closed]

Considering the short supplies of blood in hospitals, why can't we freeze on our blood from time to time and and have it stocked for reuse in an emergency? That could make ourselves responsible for ...
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0answers
47 views

Why is thrombin time longer than prothrombin time? [duplicate]

Thrombin time (TT) and prothrombin time (PT) are two different clinical measures of blood plasma coagulation. Both clotting tests end with the conversion of fibrinogen to fibrin; however, the TT ...
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0answers
23 views

How pulmonary vasculature removes embolism?

This book says: Pulmonary vasculature removes emboli before they reach into systemic circulation. I can speculate that if the emboli are made of fat or clot then our body could degrade it but how ...
2
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1answer
130 views

What is the difference between ferritin and hemoglobin?

I have been reading that ferritin is the store of iron but hemoglobin is actually the amount of this in blood. Does hemoglobin get sourced from ferritin? Is it possible for a person to be low on ...
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0answers
13 views

Non-splenic pools of erythrocytes?

In splenectomized animals, where could red blood cells be released from, to explain an increased hematocrit after exercise or muscular contractions?
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1answer
95 views

A hypothetical emergency situation

This question was posed to me by my Biology teacher: Consider a hypothetical emergency situation of a person shot by a bullet in the heart. The bullet goes into the body and comes out from it, ...
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1answer
3k views

Does a blood transfusion cure disease?

Does transferring blood between two people also transfer all the white blood cells? Why can't AIDS victims with low t-cell count just get blood transfusions till they have more t-cells? Why can't ...
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1answer
490 views

What is the speed of blood in when flows through the fingertip?

What is the average speed of blood as it flows through the index finger on the right hand?
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2answers
20k views

Why is prothrombin time test not used for heparin

Prothrombin time test is used for the monitoring of warfarin but not heparin. Why is this used for warfarin monitoring and why is it not used for heparin monitoring?
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1answer
687 views

Blood clumping in mosquitos

Will a mosquito die due to blood clumping if it sucks blood from two people who have different blood groups? What will happen in its gut? Is there any mechanism to avoid clumping? Or do mosquitoes ...
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1answer
602 views

Why do people perceive blood pressure as the force that moves the blood forwards (see details)?

For example "Veins contain a lot of valves because the blood pressure inside them is low.". This wouldn't make any sense unless if blood pressure was perceived as the force that drives the blood ...
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1answer
105 views

Is it possible to completely puncture a human hand and have no blood come out?

Illusionist David Blaine sometimes performs a trick where he takes a very long and thin ice pick, insterts it in his hand, and comes out the other side (the palm). However, there is no blood present. ...
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2answers
22k views

What happens when you mix type A with type B blood (and v.v)

What happens when you mix different blood types that are not compatible? For example, if a patient has type A blood and receives type B blood, or v.v.?
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1answer
586 views

Does Blood Loss Shorten Telomeres?

If blood loss necessitates immediate cell division to replace lost cells, does the increase in cell division correlate to shortening of telomeres? Does it further cause the Hayflick Limit to be ...
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1answer
105 views

Can we use cancer cells to generate blood vessels?

Is there any possibility to use cancer cells, which generate blood vessels, to generate our blood vessels when we are wounded or when we have varicose veins in our legs? Thanks for your answer in ...
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1answer
118 views

What do bloodsucking animals actually feed on?

A number of animals, including mosquitos, leeches, ticks and so on, feed on blood. And yet, at least in mammals, most stored nutrients can be found in body fat as fat, muscles and liver as glycogen ...
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0answers
38 views

Iron deficiency anemia [duplicate]

It is said that iron deficiency anemia is characterised by microcytic-hypochromic RBCs. I would like to ask how iron deficiency causes decrease in the volume of RBCs? If the volume is decreasing ...
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1answer
30k views

What is the difference between regular blood, a woman's and a virgin's menstrual blood?

There are many stories that blood contains the life-force energy and specifically menstrual (period) blood has always been a feature of many rituals and some ancient Sumerian tablets mentioned that ...
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0answers
260 views
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72 views

How does the composition of blood cell types in human blood change during our lifetimes?

I was reading the paper Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. There they do additional checks to see that their results are not due to differing ...
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1answer
102 views

Is Hemoglobin binding to oxygen the same as Adsorption

I have recently been reading about Hemoglobin and came across how it binds to oxygen. This seems very similar to Adsorption. Is the process of Hemoglobin binding to oxygen through Adsorption ?
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1answer
105 views

What is the reason for 'microcytic' anaemia?

I know the causes for microcytic anaemia are Fe deficiency, prolonged inflammation, Thalessemia, Sideroblastic etc. All these logically point to a decrease in Haemoglobin synthesis - either Haeme or ...
32
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3answers
148k views

Why do mammalian red blood cells lack a nucleus?

How did the red blood cell in humans get to lose its nucleus (and other organelles)? Does the bone marrow just not put the nucleus in, or is it stripped out at some stage in the construction of the ...
4
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1answer
11k views

why does blood when oxidized over time become bluish green?

Oxygenated blood is bright red and deoxygenated blood is dark red or brown. If you take oxygenated blood and leave it in the air it will turn dark red, then brown, then finally a bluish green from ...
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1answer
287 views

Does Goryaev's chamber have the same grid layout as the conventional counting chamber used in the West?

I'm translating a Russian biotec text where some cell counting operations are mentioned. The piece of equipment the authors mention in this context is "Goryaev's chamber" (камера Горяева): We ...
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1answer
1k views

How are antibodies extracted from donor blood?

When blood is donated, the antibodies within it are extracted, but how exactly do they do it? How do they take out the antibodies within the blood, what process do they go through?
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0answers
24 views

What is a normal healthy amount of Titratable acid in a person's blood?

A person's normal pH for arterial blood is 7.41 and venous blood is 7.36. But I am curious to what is a normal amount of Titratable Acid in someone's blood?
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3answers
204 views

Why ml scale blood retrieval is required to run a blood test?

Substances found in blood are present at microscopic scale and tend to be invisible to the unaided eye. Why is a whole vial of blood (at ml scale) is required to assess the presence and concentration ...
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1answer
9k views

How does aspirin “thin” blood?

As we all know, aspirin doesn't actually thin the blood, as it has been explained to me, it makes it "slippery". Slippery blood doesn't stick to itself hence this helps prevent internal blood clots (...
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0answers
82 views

Does capillary blood pressure have any effect on how much oxygen or nutrient gets distributed to tissues?

From what I have read regarding blood pressure and blood flow, I've come to the conclusion that, apart from the osmolarity of blood, the only determinant of how much oxygen/nutrients the tissues get ...