Questions tagged [hematology]

The study of blood, the blood-forming organs, along with blood diseases and their treatment.

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1answer
603 views

Veins collapse when empty

Veins collapse when empty. That's because they have thin and almost inelastic walls. What has inelasticity and thinness of the walls to do with the collapsing of the veins?
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Can the mating of a couple with Rhesus positive and negative blood types result in miscarriage?

Can the combination of $+ve$ and $-ve$ blood groups of a couple be a cause of miscarriage in pregnancy?
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1answer
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Does donating blood lower testosterone levels? [closed]

I'm a guy and I decided to donate blood because of persuasion. My testicles feel weak afterwards specifically. I mean they feel like they're compensating -- assuming that makes sense. Is this because ...
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Is blood regarded as an organ?

It consist approximately 7 percent of body weight. By definition organ is composed of multiple tissues. Blood is a fluid, a circulating tissue. Therefore can we call this fluid system a liquid organ?...
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Why do erythrocytes have no MHC1 but platelets do?

Red blood cells do not have a considerable number of MHC1 through their membranes, and that's explained by them not having a nucleus. But why do platelets have MHC1s if they have no nucleus either? I ...
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1answer
162 views

Blood Group Notation

In a textbook, I encountered a notation used when writing blood groups down, which was "I" with the blood group type as a superscript. I was curious as to why the letter "I" is used in this notation ...
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0answers
3k views

Why women have high Erythrocyte sedimentation rate? [closed]

Why ESR (Erythrocyte sedimentation rate) 1. higher in women 2. increases with age 3. increases in pregnancy, infection, malignancies what I thought so far : since women are menstruating so there ...
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1answer
215 views

Meaning of red blood cell volume expansion

In the scientific papers about EPO I read RBC volume (mL) expansion. What is it? The volume of a single cell or the volume expansion (=that is the increase of the number of cells) caused by the EPO? ...
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1answer
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Why does oxygen bind to hemoglobin in an specific angle?

There is an specific angle of the bond between oxygen and hemoglobin in lungs, which I don't know, but what interests me more is the question, why is it specific?
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What's the difference in roles of GATA-2 and BMI-1 in guiding Hematopietic cells?

I've discovered that hematopoietic cells become lineage-positive (Lin+) and go down the path of becoming lymphoblasts and myeloblasts, and that both BMI-1 and GATA-2 are transcription factors that ...
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1answer
244 views

What evolutionary reason is there for hemolytic disease?

Nowawadays we have methods which allow us to overcome hemolytic disease of newborn or to prevent it to onset. The Rh or Kell conflict, but how is it possible that it is present? Why it haven't ...
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Where does the extra blood in arterial circulation when exercising come from? [closed]

When exercising more blood is in our arterial circulation. Where did this blood come from and how did it get there ?
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1answer
503 views

Why is the pressure pulse bigger after exercise?

Right after exercise, is the amplitude of the pulse smaller or bigger than resting period? And why is that ?
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250 views

What is “multiple” myeloma?

Multiple myeloma, commonly referred to as myeloma, is a cancer of the plasma cells found in the bone marrow.(source) Is there any significance in calling myeloma as "MULTIPLE" myeloma?
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What's the smallest animal with hemoglobin running in its veins?

What's the smallest known animal with hemoglobin running in its veins? Here I mean an animal that on its own is able to produce the hemoglobin that is running in its veins. For that reason this ...
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Does drinking water from stainless steel increase hemoglobin?

I'm pretty sure iron molecules will be present in water. Cooks who use iron or stainless steel pots increase the amount of iron they consume
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1answer
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Triosephosphate isomerase deficiency

Triose phosphate isomerase deficiency, a rare condition, is the only glycolytic enzymopathy that is lethal. This deficiency is characterized by severe hemolytic anemia and neurodegeneration. How can ...
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1answer
763 views

Effect of forced breathing on RBC size

Microcytosis, i.e. decrease in the size of RBCs occurs: – In iron deficiency anaemia, – During prolonged forced breathing and – When osmotic pressure of the blood is increased. I am ...
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26k views

What percent of your blood can you lose before you need a transfusion

Losing a little blood is okay. If your a normal healthy person, and got into an accident, how do they know if you need a transfusion or if you'll be okay? This is hypothetical.
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Why does high EDTA concentration cause swelling of platelets?

According to this textbook, high ( >2mg/ml of blood) EDTA concentration causes swelling of platelets which lead to their fragmentation. I know that high concentration of EDTA increases plasma ...
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3answers
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Presence of MHC on red blood cells

Do red blood cells have no MHC? (I have often heard that they do not.) If so why are they not destroyed by immune cells?
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1answer
1k views

How is the probability of Rh type inheritance calculated?

I found somewhere on the Internet that, if parents are both Rh-positive, their children have 93.75% chance of being RH-positive and 6.25% chance of being RH-negative. My question is: How is this ...
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1answer
229 views

Roughly at least, how many types of cells comprise human blood?

A long time ago there were only three kinds - red, white, and rose platelets. Advances in cell sorters and more recently in genetic techniques and differentiation studies have led to the ...
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1answer
611 views

Human anti animal antibodies issues in blood testing

Do people have to be exposed to animals to get HAMA antibodies? Can these antibodies impact blood tests with false negatives as well as false positives?
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What does factor VIII have to do with thromboplastin formation?

I've got the following question and I'm afraid that the question doesn't match with the answer... Factor III (rather than factor VIII) is known as thromboplastin or tissue factor and it makes sense ...
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1answer
548 views

Why does ammonium oxalate cause swelling of RBCs?

From Pre examination procedures in laboratory diagnosis by Walter Guder : ...It consists of three parts by weight of ammonium oxalate which causes swelling of erythrocytes balanced by two parts ...
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Arteries used for inserting catheter

For catheter purpose, femoral and subclavian arteries are mostly used as starting point. Why? Are there other arteries which are used for the purpose?
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99 views

Is human blood useful as food?

Lacking other resources, could a healthy adult slit his wrist to feed a starving child with his blood? Would it be nutritional and would a starving dehydrated child eat it?
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What are preparation mistakes that could make red blood cells appear crenate in isotonic solution?

Thank you for your time. I separated red blood cells from a whole blood sample purchased from a blood bank. In isotonic solution, the red cells appear crenate. I would like to know if there is ...
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Can one use a hemocytometer on a compound upright microscope?

I'm posting this as a follow-up on What to look for when buying a light microscope?. The answerer states that you would need to use a an inverted microscope to count cell in the hemocytometer(counting ...
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1answer
157 views

How does one experimentally obtain a hemoglobin-oxygen dissociation curve?

I've always wanted to do comparative eco-physiology studies looking at Hemoglobin-Oxygen affinity of populations in different environments, but I can't find a protocol to experimentally measure the ...
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1answer
3k views

Can you bleed from your bones?

I was talking to my science teacher about the body specifically the red bone marrow. She said that blood is created in the red bone marrow. Does that mean that if you were to cut a fresh bone open ...
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Are there any exceptional cases in which a person with O negative blood group cannot donate?

Are there any exceptional cases in which a person with O negative blood group cannot donate or any case in which compatibility might not be established between O negative an any other blood group?
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Hemoglobin oxygen affinity curve

I have a general understanding of the Bohr effect, and that Hemoglobin's affinity for oxygen will shift depending on the conditions of the lungs and tissues. However, I'm struggling with the following ...
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What could be the reason for the large difference between sodium and potassium blood concentrations?

Reference values for sodium and potassium concentrations in blood tests are usually in the range of 135-145 mEq/L and 3.5-5.1 mEq/L, respectively. My question is what could be the reason for this (...
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4k views

Chart of blood pH across different animal species?

How does blood pH vary across species? I can't find an article or chart listing this kind of information. So far I've found bits and pieces like: Human blood pH is nominally 7.4. 7.4 seems to be a ...
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1answer
174 views

Reusing frozen blood [closed]

Considering the short supplies of blood in hospitals, why can't we freeze on our blood from time to time and and have it stocked for reuse in an emergency? That could make ourselves responsible for ...
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Why is thrombin time longer than prothrombin time? [duplicate]

Thrombin time (TT) and prothrombin time (PT) are two different clinical measures of blood plasma coagulation. Both clotting tests end with the conversion of fibrinogen to fibrin; however, the TT ...
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How pulmonary vasculature removes embolism?

This book says: Pulmonary vasculature removes emboli before they reach into systemic circulation. I can speculate that if the emboli are made of fat or clot then our body could degrade it but how ...
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1answer
142 views

What is the difference between ferritin and hemoglobin?

I have been reading that ferritin is the store of iron but hemoglobin is actually the amount of this in blood. Does hemoglobin get sourced from ferritin? Is it possible for a person to be low on ...
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Non-splenic pools of erythrocytes?

In splenectomized animals, where could red blood cells be released from, to explain an increased hematocrit after exercise or muscular contractions?
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1answer
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A hypothetical emergency situation

This question was posed to me by my Biology teacher: Consider a hypothetical emergency situation of a person shot by a bullet in the heart. The bullet goes into the body and comes out from it, ...
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1answer
3k views

Does a blood transfusion cure disease?

Does transferring blood between two people also transfer all the white blood cells? Why can't AIDS victims with low t-cell count just get blood transfusions till they have more t-cells? Why can't ...
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1answer
502 views

What is the speed of blood in when flows through the fingertip?

What is the average speed of blood as it flows through the index finger on the right hand?
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1answer
731 views

Blood clumping in mosquitos

Will a mosquito die due to blood clumping if it sucks blood from two people who have different blood groups? What will happen in its gut? Is there any mechanism to avoid clumping? Or do mosquitoes ...
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1answer
668 views

Why do people perceive blood pressure as the force that moves the blood forwards (see details)?

For example "Veins contain a lot of valves because the blood pressure inside them is low.". This wouldn't make any sense unless if blood pressure was perceived as the force that drives the blood ...
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1answer
115 views

Is it possible to completely puncture a human hand and have no blood come out?

Illusionist David Blaine sometimes performs a trick where he takes a very long and thin ice pick, insterts it in his hand, and comes out the other side (the palm). However, there is no blood present. ...
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What happens when you mix type A with type B blood (and v.v)

What happens when you mix different blood types that are not compatible? For example, if a patient has type A blood and receives type B blood, or v.v.?
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622 views

Does Blood Loss Shorten Telomeres?

If blood loss necessitates immediate cell division to replace lost cells, does the increase in cell division correlate to shortening of telomeres? Does it further cause the Hayflick Limit to be ...
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1answer
108 views

Can we use cancer cells to generate blood vessels?

Is there any possibility to use cancer cells, which generate blood vessels, to generate our blood vessels when we are wounded or when we have varicose veins in our legs? Thanks for your answer in ...