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Questions tagged [histone]

Basic (positively charged) proteins that help in compacting the genomic DNA in the form of chromatin, by forming nucleosomes.

13
votes
1answer
1k views

How are epigenetic marks transmitted during cell division?

As far as I know, this is one of the biggest questions in the epigenetic field: how are the epigenetic marks like histone modifications propagated through cell division? A lot is already known about ...
7
votes
3answers
1k views

In what sense is the “histone code” a code?

Since I started learning about molecular cell biology, I have witnessed an increasing amount of attention to this thing called a "histone code." However, unlike the central dogma of molecular cell ...
5
votes
1answer
270 views

How does “inheritance of methylation” of DNA and/or histones work?

What are the current models/ideas describing the mechanisms explaining inheritance of methylation on DNA resp. histone level? Is there evidance of this "setup" information being really duplicated/...
7
votes
2answers
643 views

Why DNA needs histones to be packaged and ordered?

I know that histones are proteins that package and order the DNA into structural units called nucleosomes, my question is Why DNA needs histones to be packaged and ordered ? Why DNA cannot do that by ...