Questions tagged [hiv]

The Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus which reproduces in human CD4-positive cells, which are primarily T-helper lymphocytes and macrophages. HIV is the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS).

11 questions with no upvoted or accepted answers
Filter by
Sorted by
Tagged with
3
votes
0answers
39 views

Do we know that PrEP actually prevents infection, rather than masking it?

Pre-exposure prophylactic treatment (PrEP) for HIV is commonly said to reduce infection rates by more than 75%. Similar treatments for already-infected patient treatments do not cure HIV, but reduce ...
3
votes
0answers
6k views

Can HIV mutate to become airborne?

HIV has a very high mutation rate due to its inability to correct errors in DNA replication and it is very adaptable to its environment. Hence I wonder whether is it possible for it to mutate such ...
2
votes
0answers
302 views

HIV and open reading frames

In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well. e.g. ...
1
vote
0answers
63 views

why hiv genome not attacked by lysosome in macrophage

HIV cells lifecycle in macrophages suggests the early phase with naked genome entering the macrophage along with reverse trancriptase enzyme. i am thinking that macrophages are abundant with lysosomes ...
1
vote
0answers
57 views

T lymphocytes and HIV-AIDS

in studying maturation of lymphocytes into two different types-T LYMPHOCYTES and B LYMPHOCYTES. it is mentioned that if a lymphocyte matures in thymus gland it becomes T LYMPHOCYTE and becomes B ...
1
vote
0answers
79 views

Can HIV be automatically cured by waiting until CD4 T cells count drop to 0?

As I know, HIV needs host cell, CD4 T cell to repicate itself, and at late stage of AIDS, count of this cell in patient will drop to 0, my question is, if we can provide a sterilised environment for ...
1
vote
1answer
209 views

Engineered CD8 T-cell therapy for HIV infection

CD8 T-cells are effective in controlling HIV during the early phase of the infection. However by the time, the virus mutates and develops an evasion mechanism against CD8 T-cells. Since cancer cells ...
0
votes
0answers
7 views

How much of the genotype-phenotype map do we understand in HIV?

From what I understand, viruses have very small genomes relative to those of standard model organisms used in biological research. For example, according to Wikipedia, "the HIV genome contains nine ...
0
votes
0answers
25 views

In HIV-1, what produces Tat?

The Trans-activator of transcription (Tat) plays a crucial role in regulating the transcription process of HIV-1. But which state of the Long Terminal Repeat (LTR) produces Tat? Is it the "...
0
votes
0answers
29 views

Which cells are prefered by the HIV virus to establish an infection?

We always read that HIV infects CD4 cells, macrophages, and dendritic cells. However, is it a common event for HIV to infect non-immune cells within a host? If not, why? And also if not, why are ...