Questions tagged [hiv]

The Human Immunodeficiency Virus (HIV) is a single-stranded RNA virus which reproduces in human CD4-positive cells, which are primarily T-helper lymphocytes and macrophages. HIV is the causative pathogen of Acquired Immunodeficiency Syndrome (AIDS).

13 questions with no upvoted or accepted answers
Filter by
Sorted by
Tagged with
3
votes
0answers
42 views

Do we know that PrEP actually prevents infection, rather than masking it?

Pre-exposure prophylactic treatment (PrEP) for HIV is commonly said to reduce infection rates by more than 75%. Similar treatments for already-infected patient treatments do not cure HIV, but reduce ...
3
votes
0answers
6k views

Can HIV mutate to become airborne?

HIV has a very high mutation rate due to its inability to correct errors in DNA replication and it is very adaptable to its environment. Hence I wonder whether is it possible for it to mutate such ...
2
votes
0answers
102 views

T-cell “exhaustion” in patients with Covid-19

Following up on my previously asked question, which asks how COVID infects T-cells in immune system. Here's a study that shows that recovered covid patients have "exausted t-cells". To quote: T ...
2
votes
0answers
306 views

HIV and open reading frames

In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well. e.g. ...
1
vote
0answers
64 views

why hiv genome not attacked by lysosome in macrophage

HIV cells lifecycle in macrophages suggests the early phase with naked genome entering the macrophage along with reverse trancriptase enzyme. i am thinking that macrophages are abundant with lysosomes ...
1
vote
0answers
61 views

T lymphocytes and HIV-AIDS

in studying maturation of lymphocytes into two different types-T LYMPHOCYTES and B LYMPHOCYTES. it is mentioned that if a lymphocyte matures in thymus gland it becomes T LYMPHOCYTE and becomes B ...
1
vote
0answers
82 views

Can HIV be automatically cured by waiting until CD4 T cells count drop to 0?

As I know, HIV needs host cell, CD4 T cell to repicate itself, and at late stage of AIDS, count of this cell in patient will drop to 0, my question is, if we can provide a sterilised environment for ...
1
vote
1answer
212 views

Engineered CD8 T-cell therapy for HIV infection

CD8 T-cells are effective in controlling HIV during the early phase of the infection. However by the time, the virus mutates and develops an evasion mechanism against CD8 T-cells. Since cancer cells ...
0
votes
0answers
11 views

If the IAVI G001 HIV vaccine proves itself, why would it work?

The IAVI G001 HIV vaccine trial looks promising. If it works, will it work by preventing a single cell from being infected, or by allowing the body to attack infected cells? What I'm trying to ...
0
votes
0answers
27 views

Eradication of HIV

If the last person with AIDS dies, does that mean the disease/virus has been eradicated forever? Since the disease can ever only be transmitted, shouldn't it be possible to completely remove it from ...
0
votes
0answers
74 views

For how long viruses survive in non-air moisture environments?

On the Internet there are plenty of information that viruses don't live long after they were exposed to air, after they starting to dry out. But it's hard to find an information on how long viruses ...
0
votes
0answers
31 views

Which cells are prefered by the HIV virus to establish an infection?

We always read that HIV infects CD4 cells, macrophages, and dendritic cells. However, is it a common event for HIV to infect non-immune cells within a host? If not, why? And also if not, why are ...