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Questions tagged [host-pathogen-interaction]

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Do all gene mutations in pathogens lead to more harmful consequences for humans?

It seems that the concern we always hear is that bacteria and viruses mutate to dodge our treatments either through random mutations or survival of the fittest. Do harmful living things ever mutate to ...
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What does it mean for Caenorhabditis species to be “pseudoparasitic”?

In this Wormbook chapter, Kiontke says that some Caenorhabditis species live "pseudoparasitically" on warm-blooded animals. What does it mean? What is a pseudoparasite? I understand a parasite to be ...
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What is the difference between transport proteins and effector proteins in gram-negative bacteria?

When considering pathogenic gram-negative bacteria, is there any difference between the function of transport proteins and effector proteins? Or are they of the same functionality? Any reference ...
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CD4+ as Monocytes cell surface receptors

Today in class, our teacher was discussing about the pathogenecity of the HIV virus. He said that the binding between HIV virus and macrophages is done by the interaction between the GP120 of the ...
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1answer
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What, other than genetic factors, influence which individual survives a parasite and which perishes?

What factors other than "good genes" are at play in determining whether one individual survives a parasite and another individual in the same species perishes as a result of the same parasite? For ...
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How do prions cross the blood brain barrier?

How does the PrP scrapie protein maintain its confirmation while going through the GI tract? How does the PrP scrapie protein cross the blood brain barrier? Wouldn't the host immune system recognize ...
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1answer
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Are there any bacterial lineages which are particularly well adapted to becoming endosymbionts?

Is there any particular bacterial lineages which contain a large number of endosymbiotic species and that inhabit a large range of eukaryotic hosts? To me, this would seem to suggest that they are ...
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1answer
51 views

Save endangered parasitic species?

It seems to be an important issue the parasitic control and even some pursue the eradication of some species. Most of the researchers in parasitology are focused on the host damage and population ...
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How Anopheles crop doesn't digest gametocytes of P. vivax?

Background According to my A-level textbook: When Anopheles mosquitoes inject their proboscises and suck up blood from human host of malaria agent, they suck all stages of malaria parasite present in ...
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Quantity of toxin release by pathogen in host

I came across these lines from this paper: Pathogenic microbes exert a broader sphere of influence by releasing a bolus of toxin that can act upon many cells within a given tissue and/or diffuse ...
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1answer
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Are there specific non-protein substances that pathogens release into their host?

Reading research articles, I have found out that proteins called effectors get released into the host cell when a pathogen attacks a host. My question is, whether pathogens also release non-protein ...
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Is honey in hot green tea unsafe?

I used Google to try to figure out what kind of mixture honey has with hot water, and I found several Ayurvedic sources claiming that honey in hot water is toxic. For example: Honey – NEVER Put It ...
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Good model for comparative genomics in relation to temperature adaptation

Can anyone suggest any highly related bacterial or parasitic species which live at very distinct temperatures, which might be a good model for comparison of genomes in regard to temperature adaptation....
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Are all pathogens parasites?

If parasites are organisms that feed on other living organisms, then aren't all pathogens parasites? I've emphasised on 'feed' because I guess the pathogens just eat us (i.e. take nutrients to ...
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Did not understand a small excerpt from a research paper

Was going through this paper, among multiple things that i did not understand, I came across this part: Each amino acid residue of a single window was encoded into a unitary bit string of length ...
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1answer
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What is a functional screen?

I was going through this paper, but did not understand a term. What is the meaning of functional screen? (I am not a biology student, I don't understand much, and a small simple explanation would ...
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1answer
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What are the limiting factors of pathogen population size in human populations?

I understand that one limiting factor in non-human animal populations is that increased pathogen populations decrease animal populations from killing them, which decreases the density of the animals, ...
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2answers
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Secretion in Gram negative bacteria

Among the 6 secretion systems in bacteria, can these 6 ways be sorted out in the order of how harmful it is to the human host? Like say type 3 is highly virulent so that comes first, but I don't know ...
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2answers
370 views

Difference between modules in KEGG Module

The KEGG module M00115 includes a set of reactions while M00542 does not have any; it just shows the list of enzymes. Is the reaction set for M00542 still unknown?
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Viruses selected by evolution

First let me apologize in advance for I know almost nothing about biology. I had a conversation today with a family member who is a bio-computer-scientist and he talked to me about what his colleagues ...
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How is cancer associated with host pathogen interaction?

Does cancer by any chance fall under host pathogen interaction domain? What I mean to ask is that, is there pathogen interaction involved in cancer? I went through this article: http://en.wikipedia....
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133 views

How host defends against S. pneumoniae capsule?

The host response involves at least phagocytosis and probably localised acute inflammatory response at least after the colonisation. I am thinking how the host can defend against pneumolysin which ...
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Predicting host-pathogen gene interaction networks

Background What we have are: ~20 genome sequences for a host species that come with gene annotations Several sequenced genomes for parasite/pathogens of these hosts Question What are the possible ...