Questions tagged [human-genetics]

The scientific study of inheritance as it occurs specifically in human beings.

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Bad Genes in Human Genome Project [on hold]

I know that we found 20,000 to 25000 genes in Human Genome Project. Now,my questions are- Are ALL THESE (20k) Genes expressed (or functioning) in our body? Is there any BAD GENE in these 20k genes ...
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Bone age And Height [closed]

My bone age is 9-10 years old i m 20 years old I want to ask will my height increase ? I really want to grow my height is 4'11.5 I m so worried about it plz help and suggest me natural ways to ...
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What is the practical use of one's DNA sample?

I have the opportunity to have my whole genome sampled and receive the raw results. What are the practical use I can make of it? I know of companies (23andMe for instance) who will process a sample, ...
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1answer
26 views

Are chromosomal microdeletions passed on?

I've been looking around but can't find a clear answer: are chromosomal micro-deletions passed on (hereditary) or not?
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1answer
117 views

Replacing, instead of repairing, DNA

I've been doing some light reading on DNA damage theory of aging. One of the main ideas from that theory that I got is that the accumulation of damage in our DNA is one of the biggest causes of why we ...
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1answer
34 views

How to determine if two mutations in a gene are on the same or different alleles?

I would like to know, except a familial study, is there another way to determine if a mutation/variation is cis or trans (i.e. on the same or different alleles)? For example by sequencing technique or ...
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0answers
30 views

What the “due to” means in the definition of heritability?

According to Wray and Visscher, heritability is formally defined as the proportion of phenotypic variation (VP) that is due to variation in genetic values (VG). My question is, what does “due to” ...
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24 views

What physical differences can be observed due to the inactivation of the X-chromosome in female monozygotic twins?

I'm doing research on twins, specifically on how to identify monozygotic twins and dizygotic twins by their physical appearance alone. Since I assume that the X-chromosome plays some part in the ...
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2answers
174 views

Why are (some) human men sexually attracted to female breasts?

Many human men are sexually attracted to female breasts. Is there an evolutionary reason for this?
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1answer
74 views

Is it possible to change the DNA of all the cells of an adult human [closed]

The process of making and transferring changes is pretty straightforward relatively speaking in an embroyo. You change the DNA of one cell and all the cells now inherit this change. But let's say ...
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1answer
69 views

If some humans inherited 3% of Neanderthal DNA, why are we 99.9% same genome? [duplicate]

Many sources say that humans are 99.5 to 99.9 percent the same. Also some sources state that some humans have 3.4% Neanderthal DNA and some don't share those genes. Why is that?
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20 views

Why can't a genetically sound human stay alive for an indefinite amount of time given all the ideal conditions? [duplicate]

I have read that even if we can control our food and lifestyle and keep things as ideal as possible, there are other factors beyond our control like effects from neutrinos passing through our body ...
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1answer
34 views

Do human genes get affected by irregular sleep and other factors

I'm new here so please go easy on me. Do our genes-the ones that carry our appearance, intelligence and other traits get destroyed or lost due to irregular sleep, excessive body heat, smoking, ...
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2answers
96 views

Rationale behind Most Recent Common Ancestor (MRCA)?

My main question is this - I heard Richard Dawkins say in a video that after 1000s of years, any given individual alive today will be either an ancestor to ALL of the humans (in that future time) or ...
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1answer
35 views

skin colouration in thalassemia

Now when i was studying about thalassemia, I read that anaemia is its major characterstic. I can understand that fact. But it was also written that the skin gets pale. Wikipedia says that the skin ...
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1answer
23 views

Repopullation after a mass extinction [duplicate]

Is it possible to restart the whole human species with less than 10 individual. let say that the whole human species was wipe out of the surface of the earth by a catastrophe only 8 different couple ...
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64 views

Why do genetic testing companies (FTDNA,AncestryDNA,23andme) express DNA shared in centimorgans (cM) instead of in number of base pairs or in percent?

Expressing DNA shared in number of base pairs or in percent of total genome would be so much simpler and easier to understand for the customers. .
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0answers
63 views

what is the difference between homozygous and heterozygous duplication?

In a genetic test result it's written homozygous duplication or heterozygous duplication Does it mean four copies of the ...
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1answer
83 views

Can I train my non-dominant hand and make it dominant?

Are our dominant limbs decided on birth or is there some way in which I can train my non-dominant hand and make it as coordinated as my dominant?
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1answer
132 views

Are all genetic disorders inherited?

I know that genetic diseases such as cystic fibrosis are often passed down through generations and are therefore classified as genetic disorders, but if a mutation occurs spontaneously, which for ...
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1answer
45 views

What labs/companies provide comparative genomic analysis? [closed]

I’m looking for labs/companies that provide comparative genomic analysis between two different species, AND do so for the “paying” public. I am looking to test a hypothesis regarding genetic ...
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1answer
32 views

X linked traits expression in females

We all know that females have an inactivated X chromosome (Most of its genes are inactivated). Consider a female who is a heterozygous carrier of an X linked abnormality, If the inactivated X was that ...
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2answers
111 views

DIYbio - CRISPR injection sites for targeting the ABCC11 gene [closed]

I've been researching into the biohacking world where people most notable Josiah Zayner and Tristan Roberts have used a CRISPR solution developed in their backyard for gene therapy. There is even a ...
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2answers
85 views

Would prehistoric humans have been considered negroid or australoid by modern standards? [closed]

What are your thoughts about this? For myself I think that the subject statement is rather obvious isn’t it, since Africans, & especially Australian Aboriginals, have the most archaic features &...
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1answer
29 views

For allele frequency determination, is it good to take samples from a college/school or a hospital or any other technique?

I am trying to determine allele frequency of a hla allele. Preliminary analysis shows the prevalence of the allele (homo or heterozygous both) is 3%. The allele is related to a disease (After exposure ...
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21 views

What is the distribution of gene polymorphism levels across human genes?

Of the approximately 19,000 human genes, about how many have one allele that occurs with appreciable frequency in the current human population, how many have two alleles, and so on? (By "appreciable ...
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1answer
34 views

How to identify whether something is in linkage disequilibrium?

If the following loci indicated the presence of an SNP in flu strains, is Locus 2 and Locus 3, which are located 10 bp apart in linkage disequilibrium? "When alleles and molecular markers are ...
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1answer
61 views

Polydactyly and its genetics

One of my friend was saying that her aunt (father's sibling sister) was having polydactyly but none of her cousins (her aunt has two daughters) is having it. What is the chance that my friend's ...
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2answers
115 views

Is it possible in modern biology to make any person's identical twin (or genetical clone) using his DNA?

I was told by a Biotech professor (who came in our college for a guest lecture) that Bio Technology has now become so advanced that if we want to make an identical twin (or Genetical DNA Twin) of a ...
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1answer
28 views

Height prediction based on genetics

My height, as predicted by my genetics, is 156 cm whereas my actual height is 172 cm. What could be the reasons for this substantial discrepancy? Does it just mean I had very good nutrition as a child?...
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1answer
19 views

what is the source of data in biological database like Genbank [closed]

What is the source of data in international biological data bases like Genbank and what is it meant for?
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1answer
17 views

Technical reason that specialized embryonic cells form

During the embryonic stage of human development, rapid cell division occurs and specialized cells form to build the various parts of the developing fetus. I'm curious: Why technically do specialized ...
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1answer
41 views

Gene frequency — database/site

Is there any free database when one can check the gene frequency in a healthy population? For example I would like to check it for genes like BIN1, CLU or CR1. On the English Wikipedia I found a gene ...
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0answers
91 views

How does the new discovery that mitochondrial dna is inherited from both parents change population genetics and other dates?

This new study seem to have pretty much proven that mtDNA is inherited from both parents. I assume that this would lead to most age estimates of ancient human ...
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2answers
129 views

Is it possible to deduce facts about a person's parents just by studying his/her genome?

As an example, suppose Anne had abusive parents. Is it theoretically possible to deduce this from her genome even if she didn't inherit this quality (of being an abusive parent)?
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1answer
43 views

Codons at for transcription vs translation [closed]

Why are start and stop codons present at translation level but not at transcription level? And how will I obtain a protein at transcription level? Thanks in advance
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2answers
111 views

Is it possible that there are two people in the world who belong to a different species? [duplicate]

There're over 7 billion people in the world and every one of them is different from everyone else. Is it possible that there are two people so different that they belong to different species (in the ...
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2answers
374 views

What type of genetic changes occurs when ovaries or uterus are removed from female body? [closed]

I saw so many women which have present dermoid cysts in their ovaries or uteruses. Doctors operate and mostly the ovaries and uterus can not be saved and the doctors remove the ovaries or uterus. ...
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1answer
37 views

Do we know which traits reside in which chromosome? If not, how about the next 10 years? [closed]

Assuming we develop a technology that allows us to make human gametes (sperm & eggs) combining chromosomes from different persons. Thus we take 1st chromosome from 1st person, 2nd chromosome from ...
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1answer
58 views

Are modern gene-editing techniques capable of creating genetically-superior versions of humans? [closed]

Can we alter the DNA in, say, a small-framed, low muscle mass male to those of elite bodybuilders? Can we alter the DNA sequence that stops balding and hair loss? How about the genes responsible for ...
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0answers
42 views

Relationship between inbreeding and sterility in humans

In general, inbred individuals tend to be at increased risk of sterility as shown in cows (Gonzales-Recio, 2007) or in leghorns (Nordskog and Cheng, 1988) for examples. I only have very quickly looked ...
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1answer
108 views

Are androgenic-anabolic steroids a form of gene editing?

Is taking AAS a form of gene-editing? Steroids alter genes in some way since they allow people to build more muscle than what's naturally possible -- so they sort of "break" natural genetics somehow. ...
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2answers
123 views

Hemoglobin question- how many alleles?

So I know that Hemoglobin is made of 2 alpha and 2 beta subunits. The alpha consists of 2 genes on chromosome 16, and the beta of 1 gene on chromosome 11. So why does Hemoglobin only have 4 alleles? ...
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1answer
80 views

Does the deletion of Chromosome 20 cause immunity against prion disease?

I was reading recently about prion disease and it caught my attention that a normal prion protein is coded n chromosome 20, therefore, in order for an infectious prion protein to attack, there must be ...
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3answers
91 views

Why is the mechanism of inheritance for this disease autosomal dominant?

An unrelated couple has a daughter and a son with the same rare condition. Neither parent has any obvious signs of the condition, but the father's mother (paternal grandmother) and her brother have ...
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3answers
739 views

Why did scientists think humans had 100,000 genes (before the Human Genome Project)?

One of the major results of the Human Genome Project (HGP) was that humans have far fewer separate genes than previously thought. From a 2004 article about the HGP: Francis S. Collins, director of ...
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1answer
32 views

What does “novel, predicted deleterious, within autozygome” mean in genetics?

I am a medical student and just got involved with a genetic lab and research. I read a lot phrases like: "Although no mutations have been reported in this gene, we think this variant is interesting ...
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2answers
113 views

What is meant by “50% related to sibling” versus “95% related to chimpanzee”?

Obviously I am more related to my sister than to a chimpanzee, so what do these different percentages actually refer to? Here is my preliminary research: https://genetics.thetech.org/ask-a-...
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1answer
108 views

Very frequent multiple births in humans

18th century Feodor Vassilyev is said to have had children by two wives, each of whom only ever had twins, triplets or quadruplets. His first wife has 16 sets of twins, 7 of triplets and 4 of quads; ...
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1answer
73 views

Can people be bred for tameness in a similar way to Russian foxes?

Russian foxes were selectively bred for tameness. https://en.wikipedia.org/wiki/Domesticated_red_fox Can a similar process happen to humans, under the right conditions - say extreme political ...