Questions tagged [human-genetics]

The scientific study of inheritance as it occurs specifically in human beings.

Filter by
Sorted by
Tagged with
3
votes
0answers
77 views

How many generations apart can a DNA test for blood relations be valid?

Suppose an American suspects he is a descendant of George Washington and he has a strand of hair of George Washington. Can a DNA test be done to prove that he is indeed a true descendant of the great ...
2
votes
1answer
776 views

Genetics and blue eyes

Blue eyes are a recessive trait in humans. I read an article recently which stated: People with blue eyes have a single, common ancestor, according to new research. A team of scientists has ...
2
votes
1answer
72 views

Do the recent findings of an ape-like creature in Europe with human-like teeth change the Out of Africa narrative?

http://www.telegraph.co.uk/science/2017/05/22/europe-birthplace-mankind-not-africa-scientists-find/ Two fossils of an ape with human-like teeth were discovered in Greece, and Bulgaria, and they are ...
0
votes
0answers
145 views

Has human evolution currently stopped? [duplicate]

Due to the advent of social networking and dating sites, it is now possible for almost anyone to find a potential mate. Therefore, there is not as much of a pressure based on physical characteristics ...
2
votes
2answers
925 views

Why is lower case used in front of a capitalized acronym (e.g. rDNA)?

Examples: rDNA, mRNA, tRNA. Why do we use small case for "r" in "rDNA", etc? Any particular reason?
0
votes
1answer
47 views

What is allele-specific gene expression?

I read somewhere that the two different alleles which we (and other species) inherit from our parents are not expressed equally in our cells. Which genes show allele-specific expression? How and why?
0
votes
1answer
61 views

HapMap 3 phased haplotype

I need to get HapMap 3 phased haplotype data. Where can I find it? Actually I need these data for specific populations and a specific gene. What is the easiest way to find data? I hope I can find an ...
10
votes
1answer
241 views

How it is determined that a particular gene or set of genes is responsible for a trait?

How it is determined that a particular gene or set of genes is responsible for a trait? Is it just a statistical analysis of people showing and not showing the trait and the genes they have (or don't ...
4
votes
1answer
2k views

Where to download gene list of human genome?

I am looking for a place where I can download a full gene list of human genome. Either by HGNC symbol or ensemble ID as long as it is usable on the consensusPathdatabase. Up until this point I have ...
1
vote
0answers
505 views

How can my sister have dark brown eyes, while my parents have blue eyes? [duplicate]

Both my father and mother have blue eyes, just like me. But my sister has dark brown eyes, contrary to what I've read about the dominance of brown eye genes and recessive blue eye genes. What happened ...
1
vote
1answer
646 views

Determine the chances of blood group type and rhesus factor of unknown parent?

First of all, I'm not a biologist so my jargon might not exactly be common on this site. I'm a programmer and as a hobby project I try to make an algorithm that does two things: Determine the ...
1
vote
0answers
32 views

Is human genome editing more complicated than mice genome editing?

A lot of genome editing trials are being done on mice and rats, but I often read that the step from mice- to human genome editing is complicated. What are precisely? I guess it has something to do ...
0
votes
1answer
63 views

How EGDS (endurance genetic distance score) is calculated?

Can anybody please make me understand how EGDS5 has been calculated to 40.8 in this paper at page#31? The formula has been described in this paper but when i tried the same, I am not getting the same ...
2
votes
2answers
551 views

Recombination frequencies

I have been learning about recombination frequencies, but an still getting a bit confused despite having gone over many of the links in Google regarding them. I was wondering if someone could verify ...
1
vote
0answers
33 views

On parents' similarity

I don't know if this is a real claim, I live in Mexico City and most of the people I know are more similar to their father than to their mother? Why is that? Are the x and y cromosomes somehow related ...
2
votes
0answers
69 views

Is a novel homozygous SNV reasonable?

I'm doing some variant discovery in a human trio (affected child, non-affected mother, non-affected father) and I have found what looks like a homozygous novel mutation. All of the aligned reads in ...
1
vote
1answer
95 views

Heritability in population genetics

What is the difference between narrow sense heritability and broad sense heritability? Does heritability in the broad sense refer to the degree of genetic determination? Heritability in the narrow ...
1
vote
1answer
731 views

Genetic pros or consequences of children born to parents of mixed nationalities?

I've gleaned a potentially flawed impression over time that a more diverse gene pool should, in theory, result in healthier progeny. Something about dominant genes promoted over recessive genes.. As ...
2
votes
0answers
53 views

Open access datasets for QTL analysis?

I'm just getting started out learning how to use the QTL package in R studio, and I'm trying to find additional datasets to practice with. I've already worked through the datasets here on the Rqtl ...
2
votes
1answer
48 views

How can I list genes present on a given series of bands?

My question is related to this one. My interest relate to this deletion: del(7)(q11q36)[12] as defined by ISCN. I would like to access a list of the genes found on the bands 11 to 36 of the 7th ...
1
vote
1answer
282 views

Understanding a Chromosomal formula in a karytope analysis

I am reading a medical reporting results of a karyotype analysis. On it it is written: Chromosomal formula 46,XX,del(7)(q11q36)[12]/46,XX[13] I understand that 46 ...
4
votes
1answer
701 views

Why is my blood group O -ve?

My parents have B +ve blood group in fact my brother also have B +ve blood group, then why my blood group is O -ve ?
5
votes
1answer
238 views

Left-handedness and Right-handedness - Are they genetic?

I have a biology book that states that whether a person will be left-handed or right-handed is determined by the genetic constitutional makeup. Is this true? As far as I knew, these traits depend on ...
4
votes
0answers
171 views

Why do female humans invest more in parental care than male humans, from an evolutionary standpoint? [closed]

As the question title suggests, why do female humans invest more in parental care than male humans, from an evolutionary standpoint? My guess is that the crux of this that males and females have ...
4
votes
0answers
59 views

How Can Homosexuality be Genetic? [duplicate]

I hold no strong opinions towards homosexuality one way or the other; I'll personally refrain, but don't apply my personal tastes to the rest of the world. I remember seeing some articles a while ...
15
votes
5answers
10k views

Do men and women have the same number of genes?

As far as I know, humans have 23 pairs of chromosomes, each one which contains a particular amount of genes. But in the "last" pair, men have a XY pair chromosome, and women have a XX pair chromosome. ...
1
vote
1answer
58 views

Are hormone secretion variations the same for a pair of monozygotic twins?

I have recently read a paper about how stress affects morning salivary cortisol levels in an individual. I am conducting a study on monozygotic twins and was wondering if cortisol levels would ...
3
votes
3answers
8k views

What is a gene transcript, how is it different from an allele?

Within human genetics, My current understanding of a transcript for a particular gene is that it's the exact nucleotide sequence and position of a particular instance of said gene in some individual. ...
4
votes
1answer
157 views

DNA mutations in CHO-KI mammalian cells

The mammalian cell line CHO-K1 has 24,383 genes. After 70 doublings (from a starting number of cells, 1) a total of ~4,000 mutations have occurred in the overall population of cells (i.e. not all in ...
0
votes
1answer
122 views

How closely related will your descendants be to you?

I wonder how similar my DNA will be to that of my great-grand-children. If a new person enters my family tree every new generation, he/she will bring in half of his/her DNA, therefore decreasing the ...
3
votes
0answers
77 views

Is Phenylalanine hydroxylase gene biallelic?

Since the PAH gene is biallelic, and there are many disease causing mutations, most PKU patients are compound heterozygotes. (paper) Compound heterozygosity in medical genetics is the condition ...
2
votes
0answers
67 views

Mosquito vs Human: Swapping the roles

Is there a known mosquito-specific lethal (for some relevant species of mosquitos) virus that you could safely (for the humans) put into the blood of living humans? Is it technically possible to ...
6
votes
2answers
519 views

What is the right definition of 'Sex Linkage'?

I am confused about definition of "sex linkage". I have found different definitions but they do no match. From P.S Verma, V.K Agarwal cell biology, genetics, molecular biology, evolution and ecology: ...
6
votes
1answer
165 views

Why are X-linked illnesses less common in females if females have X-chromosome inactivation anyway?

I have read this post but am still slightly confused about this. Do tissues in the human body not all develop from the same cell(s) in the embryo? If so, I do not see how the cell 'mosaic' would be ...
1
vote
1answer
492 views

Sex linked genes?

I am learning about genetics and sex-linked traits. All of the X-linked traits we have considered (eye colour in Drosophila, Duchene Muscular Dystrophy to name a couple)follow the rule that, a female ...
3
votes
0answers
1k views

Are epicanthic folds a dominant trait?

My state (Tripura) originally had a mostly mongoloid-feature-possessing population (ethnic group: Tripuri). Recently a large number of non-mongoloid people (ethnic group: Bengali) have migrated to ...
5
votes
2answers
112 views

Is this formula describing the loss of unfixed genes from a population accurate?

In the 1954 science fiction novel Search the Sky by Frederick Pohl and Cyril M. Kornbluth, a formula is featured that "quantitatively describes the loss of unfixed genes from a population". $$L_T=L_0 ...
8
votes
2answers
8k views

If a mother had a child with her own son, could a paternity test yield positive result for the son's father?

Let's imagine a family composed of Mr A and Mrs B, who have a son named John. Now, if for whatever twisted reason, John had a child with Mrs B, could a paternity test yield positive result for Mr A ? ...
1
vote
1answer
150 views

Can epigenetic structures carry a trait?

Can epigenetic structures cause a trait to manifest in a person if the trait is not already in the DNA? In all my readings I have yet to find a definitive statement that it is impossible.
4
votes
1answer
175 views

Why does this karyotype start numbering at 11?

Here is some image I found for karyotyping a chromosome: Why does the band numbering start at 11? When I count other things I usually start with the number one, and in some cases zero. Eleven seems ...
0
votes
1answer
502 views

Why we aren't making Darwin's theory a Law [closed]

I was wandering about darwin's theory which is controversial theory and there are no enough evidence to prove it right or falsify it, since I'm a biology student so i studied basic way of a hypothesis ...
2
votes
0answers
1k views

Is Gorlin's sign hereditary?

"Gorlin's Sign" is the ability to touch the tip of the nose with the tongue. It is present in half of people with Ehlers-Danlos syndrome, but is also present in a minority of people without that ...
8
votes
2answers
12k views

Why babies cry after they are born?

Well I have noticed that almost all of the babies cry after birth, but some of them (1 to 1,000,000? births) don't cry. So, we have: Why is this happening (the cry after birth)? Also why animals ...
1
vote
0answers
122 views

Why is the total length of Introns greater than the total length of exons?

I have just been reading that typically the total length of the Exons of a split gene is very much smaller than to total number of its Introns. Could anyone please explain why this is the case if its ...
3
votes
2answers
142 views

How early can we know the sex of a human being now?

Do we need to wait till a Zygote forms?
1
vote
1answer
131 views

Correlation between genetic distance and birth defects

It is folk knowledge that in-breeding causes birth defects due to similarity of genetics between parents. Consequently, is there a similar correlation between genetic distance of parents and ...
0
votes
2answers
2k views

Do all polygenic traits involve epistasis?

Consider the following statement All polygenic traits involve epistasis. I think its true because polygenic traits involve several genes interacting together to result in a certain phenotype and ...
2
votes
1answer
119 views

Commensalism with Virus bacteria [duplicate]

Why people die of infection from microorganism, when germs can keep breeding for longer if they dont kill host? Would not millions of years of evolution make germs evolve to not to kill human but feed ...
12
votes
2answers
2k views

Online phylogenetic tree of human lineages

I am looking for a source of information about the diversity of human lineages and their relationships. With a quick google search it is easy to find this type of tree A perfect online resource ...
3
votes
1answer
212 views

How to predict future generations from heritability

The heritability of human intelligence is estimated to be around 0.5. There are of course various estimates, some lower, some higher. But let's work with this value of 0.5 for the moment. I wanted ...

1 2 3
4
5
8