Questions tagged [immune-system]

This tag is for general questions related directly or indirectly to the vertebrate immune system, but are not questions directly related to Immunology, the discipline of the study of the immune system.

36 questions with no upvoted or accepted answers
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How does the immune system fight scabies mites?

After a distressing episode involving my elderly mother and a nursing home, I've been reading up on scabies. It seems that in healthy people, the immune system limits the mite population to around 10 ...
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0answers
141 views

How much time does it take for the naive T Cell to get activated?

Suppose a naive T cell comes in contact with an APC. How much time does it take for the T Cell to get activated and within how much time does the T cell move away from the APC due to incompatibility ...
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9 views

What is the mechanism responsible for long-lasting detectable antibody titers?

As I understand, when naive B cell encounters antigen matching its receptors and is activated by a T helper cell, it can either differentiate into 4 plasma cells, produce a lot of antibodies and ...
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0answers
34 views

Does antibodies get produced in female body against sperms?

Our immune system produces antibodies against any foreign particles entering our body.In female body sperms are a foreign particle .Does females produce antibodies or some sort of chemical resistance ...
2
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0answers
45 views

How does the white blood cell ‘hunt’ the bacterium?

There's this mildly viral video which reportedly shows a white blood cell hunting a bacterium: https://www.youtube.com/watch?v=JnlULOjUhSQ What I don't understand is - at this scale, how does the ...
2
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0answers
23 views

What is the end-point of material from an apoptotic cell, after phagocytosis?

Apoptosis occurs. The organelles and interior material form apoptotic bodies that are packed in vesicles. The cell membrane breaks apart (cell no longer exists) and apoptotic bodies enter the ...
2
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2answers
135 views

Is a species lifespan affected by meat consumption?

I read a review-like article about the hypothesis of Caleb E. Finch in a science magazine. The article of interest engages with the idea of Finch "[arguing] that immune functions and nutrition ...
2
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0answers
128 views

The difference between Mast Cells and Basophils

While reading the Wikipedia article on Mast cells, I came across something that confused me. What is the major difference between a Mast Cell and Basophil? They both seem to do the same exact ...
2
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0answers
323 views

Regarding Passive Aritficial Immunity: Why does the concentration of the foreign antibodies decrease over time?

So, like suggested in question, I am extremely confused about this one concept. That whether or not the injection of foreign antibodies ( passive artificial immunity ) triggers an immune response. ...
2
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0answers
54 views

What natural defence mechanism does the human body have against lead poisoning?

It is known that lead ion takes place of necessary ions, like calcium, in the body, but does not perform their task, hence wrecking the system. So how does the body eventually recognise this threat ...
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0answers
2k views

What is significance of opsonization?

Wikipedia says Antibody opsonization is the process by which a pathogen is marked for ingestion and eliminated by a phagocyte. Opsonization involves the binding of an opsonin, e.g., antibody, to ...
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0answers
126 views

Do symptoms of common cold infections correlate with the infectious agent?

The common cold - in summary, an acute upper respiratory tract viral infection - is one of the most frequent viral infections in humans and can be caused by about 200 viral types [Eccles (2005)]. ...
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1answer
110 views

How some virus are able to reach the CNS?

I know that the lymphocytic choriomeningitis virus (LCMV) could provoke meningitis and encephalitis when this virus reaches the brain. However, there are other viruses like Varicella (VSV), ...
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1answer
38 views

Immune response to foreign protein

In the context of COVID-19, why is it possible to inject someone else’s antibody protein into a person without fear of stimulating an immune response. Does this indicate that, somehow, antibody ...
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0answers
38 views

Do person with strong immune system have less chance of surviving SARS-COV-2 attack?

In most of the cases dealing with SARS-COV-2 disease, the major mortality cause is due to cytokine storm in response to Corona-virus that also attack healthy organs causing multiple organ failure. ...
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14 views

Can intracellular protein initiate strong immune response?

Some autoantibodies escape immune tolerance and can cause autoimmune disease. In order to cause harm to the tissues by these autoantibodies, do the antigen need to be extracellular or membrane bound, ...
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61 views

Is this trial that reversed aging in humans worth taking seriously?

In September 2019 Fahy et al. published results from the TRIIM (Thymus Regeneration, Immunorestoration, and Insulin Mitigation) trial. Their stated goals were to investigate whether they could restore ...
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1answer
70 views

What determines if a small protein / large peptide is immunogenic?

I'm wondering if there is some threshold in size or a specific structural property that determines if a small protein or large peptide would cause an immune reaction. Context: there are a number of ...
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22 views

Do people have local immunity?

I mean the immunity that covers only one body part or skin area after exposure to the infection but does not cover the whole organism.
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39 views

Can cell mediated immune response be transferred via blood transfusion

I read that human body can develop cell mediated immunity to viral infections and subsequently clear the virus. For example, people clear warts through cell mediated immune response against the wart ...
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0answers
19 views

What is the difference between cytokine and chemokine?

I often see these terms being used in inflammation, and I'd like to know, are they synonymous with each other or do they mean different things? Also could someone provide an example of each?
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30 views

Is there a organ or type of cell that makes Nagalase?

Schindler disease / Kanzaki disease is being described as alpha-N-acetylgalactosaminidase deficiency. So then, which organ or cell(s) produce this alpha-N-acetylgalactosaminidase (Nagalase) ?
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268 views

Does testosterone weaken the immune system?

I was reading this articles here that states that the higher the blood level of testosterone is, the weaker the immune system gets. I read another article about testosterone here that focuses on the ...
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218 views

What is the difference between an active and inactive T helper cell?

1- Are all inactive T helper cells "T memory cells" ? 2- Is there anything such as active T memory cells ? 3- I have noticed that there is also a third type of T helper cells but i dont know what it ...
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67 views

In the event of an abrasion, do mast cells cause vasodilation or vascular constriction?

Or both? I am unsure as to what mast cells will do in the event of a wound either on the epidermis or the epithelial. I know they secrete factors that mediate vascular constriction / dilation, but I ...
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0answers
91 views

Meaning of proliferation rate of 3 day−1

The abstract of an article in Journal of Virology contains the following line: We find that CD8+ cell proliferation begins 1 to 2 days after infection and occurs at an average rate of 3 day−1, ...
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85 views

Do allergens have structural similarities to pathogens?

The conventional popular explanation of allergies is that the immune system confuses allergens with pathogens and reacts to them as such. Is there any merit to this explanation? If so, I would ...
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0answers
70 views

Why does a centrocyte have a cleaved nuclei?

Why does a centrocyte have a cleaved nuclei? Is there a biological reasoning behind this phenomenon or is it the nature of the centrocytes? Does the selected centrocytes proliferate too?
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36 views

Are immunosuppressors necessary after a bone marrow transplant for Bubble Boy Syndrome?

I know that under normal circumstances, immunosuppressors are needed to mitigate the host body's immune reaction to the graft. However, people suffering Bubble Boy Syndrome have pretty much no immune ...
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0answers
31 views

How do microbes develop resistance to anitmicrobial peptides?

I would like to better understand how bacteria use the "strategy" of alternations to lipid A and membrane proteins in order to resist antimicrobial peptides of the immune system? It is my ...
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1answer
14 views

How can I detect which antibody is produced by the B cell?

I mean ,In primary response IgM is produced (IgD as well) ,In secondary response various types of antibodies are produced . So how do I detect which antibody is B cell is producing at a time.
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17 views

How antibodies are produced in our body against intracellular proteins of infectious bacteria?

When an infectious agent invades our body, then surface antigens of the infectious agent are detected by our immune system and B-cells get activated. However, we do have antibodies in our blood ...
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1answer
40 views

Immune response to IgA positive bacteria

If certain bacteria can be coated with IgA in vitro, does that mean they are likely to elicit an IgA immune response? Edit I'm working on a project that involves IgA-Seq analysis. Bacteria are coated ...
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23 views

How do T cells deal with the obstructions in their path of migration?

When T cells move in the blood, are their any obstructions(other cells) while they migrate? If there are then how do the T cells overcome such obstructions in their path? Do they move past them or ...
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885 views

How lymphocytes in lymphatic system get oxygen?

We know that the gas-transporting protein hemoglobin is absent from the lymphatic system. So, how does gas transportation takes place in lymphatic system? Is mere diffusion from surrounding blood ...
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1answer
50 views

Why do viruses cause different symptoms?

If the sole purpose of a virus is to hijack the nucleus of a cell to replicate, why do we have different symptoms for different viruses? I can think of the following comming into play: immune ...