Questions tagged [insulin]

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Why does activity cause hypoglycaemia in diabetics?

(I'm from the UK so I'll be using mmol/L as units and taking <4.0 as hypoglycaemia.) I remember being told that I should consume a small amount of sugar or reduce insulin dose sightly to increase ...
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How is an extreme insulin overdose counteracted

I just watched this comedy skit that went - Trainee: I just gave him 10 of insulin Doctor: 10 what? Trainee: 10cc Doctor: * look of terror * As a diabetic myself I know that 10cc or 1000u is an insane ...
Ethan's user avatar
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79 views

Why do some people accumulate more diglycerides in their muscle cells?

The scientist Gerald Shulman has experimentally found that young lean adults in their early twenties that are children to people with type 2 diabetes often show muscle insulin resistance. He found ...
Agerhell's user avatar
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1 vote
1 answer
26 views

Can monoclonal antibodies be used to transport insulin

Quick question Monoclonal treatments in cancer require the drug attached to the antibody which then attaches itself to the neoantigen on a cancerous cell, would it be possible to transport insulin in ...
Brian's user avatar
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2 votes
1 answer
123 views

How do receptors lose their sensitivity?

Recently, I learned that one of the causes of Type II diabetes is that insulin receptors on cell surfaces lose their sensitivity due to long-term high exposure to insulin (which occurs as a result of ...
F16Falcon's user avatar
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3 votes
2 answers
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Would intravenous insulin + glucose significantly accelerate glycogen synthesis?

Would an intravenous injection of insulin + glucose result in significantly quicker replenishment of exhausted glycogen stores than an injection of glucose alone? This is a strictly theoretical ...
Jan's user avatar
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1 vote
0 answers
40 views

Dangers of excess blood protein? [closed]

Like glucose, amino acids are also insulinogenic as well. So, presumably, just like glucose, the body would also like to keep amino acids levels in the blood stream below (or within) some certain ...
ManRow's user avatar
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1 vote
0 answers
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sweet receptor's affect on insulin release

So I understand the basics of how the body releases insulin to keep blood glucose levels in check and (loosely) that higher insulin levels can lead to more (or at a faster rate) glucose being stored ...
Daveh0's user avatar
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1 answer
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Full name for stem cells

So during research, my professor mentioned a type of stem cell, a name that was like 5-6 words long, that can be used to treat diabetes by creating an "artificial organ". That hypothetical organ would ...
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2 votes
1 answer
385 views

Is the Insulin Receptor Considered an Enzyme?

Can we consider insulin receptor an enzyme? In other words, does the insulin receptor have enzymatic characteristics?
Reem M.Al Haj's user avatar
-1 votes
1 answer
123 views

The insulin protein of apes & chimpanzees [closed]

How many amino acids do the insulin protein of apes and chimanpzees compose of?!
K. M.'s user avatar
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5 votes
1 answer
6k views

Why doesn't glucagon promote glycogenolysis in muscle?

Insulin stimulates glycogenesis in both liver and in muscles. Epinephrine stimulates glycogenolysis in both liver and muscles. But glucagon stimulates glycogenolysis in liver only. Why is this so?
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2 votes
1 answer
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Activation of Glycogen Synthesis by Insulin - mechanism and cellular location?

My textbook states the following... Insulin activates enzymes that convert glucose to glycogen. Does this conversion occur inside or outside the liver and muscle ...
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2 votes
1 answer
3k views

Why do some tissues have insulin-dependent glucose transporters and others not?

Insulin upregulates GLUT-4 glucose transporter insertion in skeletal muscle and adipose tissue. But there are many tissues in the body that use insulin-independent glucose transporters (like GLUT-3 in ...
rorty's user avatar
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1 vote
0 answers
42 views

What risk does the insulin pump hack carry?

Recently, a OneTouch system was hacked, potentially allowing any malicious attacks, draining the pump into someone's bloodstream: Jay Radcliffe, a diabetic and researcher with cyber security firm ...
Kaz Wolfe's user avatar
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1 vote
1 answer
1k views

Role of the Hypothalmus in the control of Blood Sugar

In homeostatic regulation of blood glucose, the receptor and effector is the Pancreas, but how does the control centre — the Hypothalamus — connect and link into this process?
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1 vote
0 answers
52 views

Is it comfirmed that Alzheimer's is a diabetes of the brain?

I read in this New Scientist report, that the mental decline during diabetes may be an early stage of Alzheimer's. The hypothesis was based on a study with 20 rats. Has there been any follow up ...
Strategy Thinker's user avatar
10 votes
3 answers
29k views

What happens if a non-diabetic receives an injection of insulin?

If a person without diabetes or any diabetes-related issues receives an injection of insulin, what happens? Would the blood glucose level drop or does the body naturally compensate for the added ...
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1 vote
1 answer
316 views

Which of the three is true for insulin receptors?

I have seen the following question in a Cell Biology exam: Which of the following is true" Insulin has an hydrophobic Signal Peptide and the insulin receptor does not have an hydrophobic Signal ...
user135172's user avatar
7 votes
4 answers
849 views

Is Insulin-Glucose dynamic Lotka-Volterra?

From Wikipedia: The Lotka–Volterra equations, also known as the predator–prey equations, are a pair of first-order, non-linear, differential equations frequently used to describe the dynamics of ...
Fraïssé's user avatar
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9 votes
1 answer
604 views

If eating 100% fat 2 times more worth the energy I spend during the day, will I store body fat?

So in theory, insulin hormone is the one that tells the body "eat more. don't burn body fat". Alongside with glucose blood level regulation and turning excessive glucose into liver (which later goes ...
knitevision's user avatar
9 votes
1 answer
293 views

Do blood glucose "spikes" contribute to insulin resistance, or is prolonged elevation required?

There's increasing public discussion about the health risks of chronic insulin resistance* (IR). In many cases there's a focus on high glycemic index foods that "spike" your blood sugar, which implies ...
octern's user avatar
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2 votes
1 answer
1k views

Production of processed Insulin in bacteria

Genetically-engineered bacteria are used to produce insulin in industry, but as far as I know, the bacteria can produce only proinsulin. Why is that? What happens in the human body in order to make ...
Robertos's user avatar
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6 votes
1 answer
902 views

Genetic engineering for insulin production

In order to put human DNA inside a bacteria in order to have it create Insulin, from what type of cell would you need to take the gene for insulin? I thought it should be from any somatic cell, since ...
gil_bz's user avatar
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