Questions tagged [karyotype]

The number and morphology of chromosomes in eukaryotic nuclei and analyses related to measuring the karyotype.

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How to use karyotype notation?

I'm looking at two karyotypes, one for a person with Klinefelter's Syndrome and another with Patau's. What is the karyotype notation for them? I don't understand what I looked up online. Any help is ...
John Liu's user avatar
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Why do some karyotype graphs contain 46 pairs of chromosomes?

The human genome consists of 23 pairs of chromosomes. Two copies of each pair connect to each other at the centromere. Normal karyotype graphs should look like this: But some karyotype graphs contain ...
seamos's user avatar
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De novo mutation selectivity

I was recently reading about genetic diseases and came to understand that many of them are caused by de novo mutations in the prezygotic or early embryonic stages of the life cycle of the organism. ...
Dhyey Gandhi's user avatar
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number of chromatids seen in karyotype

The karyotype is performed on a cell whose cycle has been stopped in metaphase or pro metaphase, using colchicine or by other means. In the textbooks I read that during the S phase each of the 46 ...
piadinas's user avatar
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Appearance of Karyotypes in educational material

Most actual karyotypes online appear as single chromosomes (unreplicated). I was under the impression that a micrograph of the replicated chromosomes was taken during metaphase of mitosis and thus ...
Steven Cotrone's user avatar
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Polymorphism in number of chromosomes?

The answer to this question, saying that Down Syndrome - a trisomy of human chromosome 21 - is caused by de novo mutation (rather than resulting from standing variation) made me think about ...
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What are homologous chromosomes?

I've read that homologous chromosomes are composed of one maternal chromosome and one paternal chromosome. I want to confirm if this image is for one set of homologous chromosomes: They have the ...
Via Lo's user avatar
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Understanding a Chromosomal formula in a karytope analysis

I am reading a medical reporting results of a karyotype analysis. On it it is written: Chromosomal formula 46,XX,del(7)(q11q36)[12]/46,XX[13] I understand that 46 ...
Remi.b's user avatar
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Why does this karyotype start numbering at 11?

Here is some image I found for karyotyping a chromosome: Why does the band numbering start at 11? When I count other things I usually start with the number one, and in some cases zero. Eleven seems ...
William Entriken's user avatar
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Why does size decrease across the sequence of human chromosomes?

The following graph shows a decrease in the number of base pairs per chromosome across the sequential set of human chromosomes: Is this because chromosomes were originally numbered by their size on ...
SANBI samples's user avatar
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Is there a karyotype database for human cell lines?

I'm looking for the karyotype of a specific cell line. Some karyotypes are well known, such as HeLa or some carcinomas, but some are very hard to find, such as LG2 (B cells). Is there a database ...
Renaud's user avatar
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