Questions tagged [liposomes]
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Why do the COVID vaccines contain the cationic lipids they do?
Why did Moderna & Pfizer specifically pick their SM-102 and ALC-0315 cationic lipids with tertiary amines, branched tails, long linker chains, and small hydroxyl head groups? Are the large tails ...
Estimation of tissue-partition coefficients and clearance for liposomic nanoparticles
I am working on developing a PBPK model for liposomic nanoparticles used to deliver drugs to fells in the bloodstream. However, I do not have any in vivo data or in vitro data. Given only chemical and ...