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Questions tagged [liposomes]

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Why do the COVID vaccines contain the cationic lipids they do?

Why did Moderna & Pfizer specifically pick their SM-102 and ALC-0315 cationic lipids with tertiary amines, branched tails, long linker chains, and small hydroxyl head groups? Are the large tails ...
user64751's user avatar
1 vote
1 answer

Estimation of tissue-partition coefficients and clearance for liposomic nanoparticles

I am working on developing a PBPK model for liposomic nanoparticles used to deliver drugs to fells in the bloodstream. However, I do not have any in vivo data or in vitro data. Given only chemical and ...
TanMath's user avatar
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