Questions tagged [literature]

Questions about scientific journal papers, books or other written sources, or for requests for references.

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14
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1answer
2k views

How does paracetamol work?

Hinz et al. 2008 found that COX-2 may be inhibited by paracetamol, and this is attributed to it's analgesic and antipyretic properties. However there are other more recent claims from Andersson et al.,...
12
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5answers
712 views

Introductory literature for synthetic / systems biology

I am a computer engineer (MSc in Computer Engineering) who's looking to switch into the field of synthetic / systems biology. I have a comprehensive layman's understanding of evolution, genetics, ...
11
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3answers
7k views

How much energy does a lion contain? [closed]

I was looking into the following problem: Obviously, the solution lies in how much energy either can output per unit of time. The total energy output of the sun is $3.8×10^{26} \frac{J}{s}$. The ...
11
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1answer
821 views

Did not understand a small excerpt from a research paper

Was going through this paper, among multiple things that i did not understand, I came across this part: Each amino acid residue of a single window was encoded into a unitary bit string of length ...
10
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1answer
2k views

What is the difference between organelle membranes?

Cells and organelles are contained in lipid bilayers. I'm particularly interested in eukaryotic organelle bilayers and the biophysicochemical differences between them. Many papers assume a ...
10
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0answers
294 views

Anatomical Angle Made by the Fingers of an Extended Palm

Does the angle made by the fingers (excluding the thumb) of an extended palm (as shown in the figure below) have a name (such as the Lovibond or Cobb angle, for instance) ? I have already checked ...
9
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3answers
2k views

What are the benefits of elucidating the crystal structure of a protein?

I have spent months as a student working on trying to form a tricky protein crystal. But I have never actually had explained to me why the structure will be useful. Once elucidated, what can we ...
9
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1answer
545 views

How does membrane potential vary between intraceullar membranes and the cellular membrane?

Question Does each type of membrane have a different membrane potential? I'm especially interested in answers that can cite academic papers that have attempted to measure membrane potentials. ...
8
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5answers
974 views

Book/source for learning bioinformatics, focused on genomics?

Does anyone know of sources for learning bioinformatics, focused on genomics? I would like to learn alot of skills I could apply potently in the workforce if I ever became adept at the fields. My ...
8
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1answer
372 views

Start studying mathematical biology from basics

I am really passionate about theoretical and quantitative biology and I would like to build my future career around this topic. I've just got my bachelor's degree in biology (ecology) but scince I've ...
7
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4answers
680 views

Books for biology,popular but rigorous? [closed]

There are very goods in physics and mathematics (like Feynman lectures for exemple) that give an elementry but but broad view of their,therefore I'd like for help to find help to find a biology book ...
7
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5answers
634 views

How can I search for and find specific biology topics in scientific journals?

I looked on google to find "scientific paper on biological explanation of homosexuality" but nothing comes up that appears reliable or from a journal. Then I looked up "scientific journals" and I ...
7
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4answers
689 views

Modern immunology textbooks

I am looking for recommendations to good textbooks introducing modern immunology. Review articles, preferably modern (post 2000) would also be useful. Please, include a brief comment with each book ...
7
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1answer
1k views

Time spent in phases of cell cycle

I am looking for references to papers containing the time intervals spent in different phases of the cell cycle (ej., G0, G1, S, G2, M for eukaryotes) for different cells. In particular, I am ...
7
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3answers
102 views

Global database for patients with rare and important injuries or disease?

I was recently reading Christof Koch's The Quest for Consciousness, and several times he mentioned how important some patients with sad and terrible brain injuries were for the understanding of the ...
7
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2answers
176 views

Examples of references for mathematical approaches in bioinformatics that are applicable to linguistics?

Do you have any classic references for mathematical approaches in bioinformatics that are applicable to linguistics (or vice versa)? EDIT I am mainly interested in approaches to reconstruct the ...
7
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1answer
2k views

Alfred Jost's rabbit experiment: how did he actually do it?

I was watching a Crash Course on Biology YouTube video by Hank Green: Great Glands - Your Endocrine System. Hank humorously describes a sex determination experiment by Alfred Jost as follows (...
6
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3answers
229 views

Did early 20th century researchers state why they used E. coli as a model organism?

I am investigating the early uses of E. coli as a model organism. Sadly, many early 20th century papers are not in English. In those that are, I have been unable to find explicit statements as to why ...
6
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4answers
607 views

Is Insulin-Glucose dynamic Lotka-Volterra?

From Wikipedia: The Lotka–Volterra equations, also known as the predator–prey equations, are a pair of first-order, non-linear, differential equations frequently used to describe the dynamics of ...
6
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2answers
5k views

How did the endoplasmic reticulum come to be?

Organelles are sub-cellular compartments in cells. However prokaryotes don't use organelles to organise their intracellular space. Evolutionarily, there is evidence that mitochondria and ...
6
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1answer
109 views

Evolution of diversity and extinction resistance

I saw a comment on an answer to another question that touched on an interesting topic: keeping diversity is useful for parameter exploration or to adapt to future environmental change My initial ...
6
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1answer
199 views

Current understanding of abiogenesis

I am trying to understand the current work on abiogenesis in biology, e.g. primordial soup, the Miller-Urey experiment, etc. How has our understanding of abiogenesis been revised since the Miller-...
6
votes
1answer
69 views

Where should I go for online information on animals endemic specifically in Mozambique?

I've been involved with the citizen science project "Wildcam Gorongosa" for over half a year now (website, forum). As there are lots of unexperienced volunteers, many questions are being asked. Often ...
6
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2answers
401 views

Measuring fitness / lifetime reproductive success (LRS) in Drosophila

I am planning a fitness assay of Drosophila melanogaster. I'd like to get a good measure of lifetime reproductive success (lrs) but I don't want to count all the offspring produced over a lifetime by ...
5
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2answers
2k views

How can I text-mine full-text articles from PubMed? [closed]

I want to do a text mining study using full-text versions of articles I find on PubMed. My intended search protocol will be roughly as follows: Search PubMed using a gene name (and any alternate ...
5
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2answers
132 views

Books about famous experiments in biology - 'methods of investigation'

I'll explain briefly what I need (hoping to find something) : I wanted to know if someone knew about a book that in a way or another talked about the greatest experiments in biology (Griffith, Avery-...
5
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1answer
141 views

Which Darwin book (and today edition) is illustrated by his own drawings?

I am interested in buying Charles Darwin books and mostly drawings (nowadays editions, I am not a collector). Please, can you advise in which book and which edition I can find the most of his drawings?...
5
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3answers
576 views

Good book on Origin of Life [closed]

What is a book that goes into reasonable detail (but isn't textbook-level technical) about the origin of earth and in particular the origin of life on earth? Something intended for a broad audience, ...
5
votes
1answer
216 views

Which literature/study/myth spurred the idea that urine is sterile?

There is a seemingly unfounded mantra that a person's urine is sterile who is not suffering from a UTI. So far I have found convincing evidence to the contrary; urine is not sterile. This poster ...
5
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1answer
394 views

What is a good identification key for European mushrooms?

I live in the Netherlands, and I am looking for an identification key for mushrooms. Are there any keys you could share?
5
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1answer
116 views

Specific examples of signalling pathway using logical 'OR' and 'AND'?

I have read here that "signals from two different pathways may be needed to activate a response, which is like a logical "AND." Alternatively, either of two pathways may trigger the same response, ...
5
votes
1answer
272 views

Is there a difference in cytoplasmic pH between prokaryotes and eukaryotes?

The cytosolic pH in human cells is around 7.4, but fluctuates as the cell is replicating. Prokaryotes and eukaryotes are vastly different in many ways. One thing they share is cytoplasm. Is there any ...
5
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1answer
239 views

Modern reference for Kropotkin's lazy bees

I have been reading through Peter Kropotkin's Mutual Aid: A Factor of Evolution and he mentions a curious fact about bees (bolding by me for emphasis): predatory instincts and laziness continue to ...
5
votes
1answer
161 views

Molecular psychology/psychiatry literature/articles

I am new biology student which is on molecular biology subject on university. I would like to know something about genetic related to neurobiology, and certainly molecular psychiatry/psychology, ...
5
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2answers
292 views

Is nucleoside-triphosphate delivery to RNA or DNA polymerase active or passive?

Are nucleoside triphosphates (NTPs) actively delivered to RNA polymerase (similarly dNTPs to DNA polymerase) through some active chaperoned process, or are they so abundant in the nucleus that they ...
5
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1answer
188 views

Is there a biological explanation for perceived deeper cognition whilst on cannabis?

Cannabis has been associated with literature, arts, and culture for centuries. There are a few features of the drugs affect on the human mind that account for this, however it remains illegal in most ...
5
votes
2answers
114 views

Is there a standard reference for the importance of tumor heterogeneity?

In a recent post, Philip Gerlee highlighted the two biggest contributions of mathematical oncology to cancer research: (1) increasing focus on the progress of cancer as an evolutionary process, and (2)...
5
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1answer
94 views

white blood cells and cancer cells transport through lymphatic vessels

It is a well-known fact that both of these cells can reach the lymphatic vessels from interstitial space. How does it do so physically? Are there any mathematical models describing this process? It ...
5
votes
1answer
2k views

What is needed for a G-matrix?

I have been doing a lot of reading on quantitative genetics and the G- (and B-) matrix lately. I get the principle behind performing the analysis now but I am still not sure how to do it. I'd like to ...
5
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0answers
161 views

Where can I get numerical data for the PAR (photosynthetically active radiation) curve?

I'm trying to do some rough figuring to calculating efficiencies of various light sources for growing plants. I'm hampered, however, by the lack of a curve to multiply by the spectrum of light ...
4
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2answers
3k views

Where can I find a list of common enzyme cofactors and/or co-enzymes?

Where can I find a list of enzyme cofactors and/or co-enzymes, ordered by how common they are? For example, $O_2$, $H_2O$, $ATP$, $ADP$, $NAD$, should be ranked in the first places, because they ...
4
votes
1answer
197 views

Can a novel protein domain arise de novo in nature or did all protein domains evolve from a single ancestor?

I know there is extensive research into the taxonomy and evolution of protein domains and many connections are, and are continuing to be, found between numerous domains. However, as far as I can see, ...
4
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1answer
61 views

Is there a database of pollen-seed distances across plant species?

I was enjoying Richard Smith's excellent answer to this question, and wondered: If you consider the pollen/seed distribution range to be plant locomotion, is there a database that compares these ...
4
votes
1answer
98 views

Looking for the closest example of life forms similar to some mathematical patterns

Caveat: this is my first question here, it is quite interdisciplinary, but I hope to be in the correct place to ask. I am a user of Mathematics Stack Exchange since some years ago, and this question ...
4
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0answers
70 views

Kinetic mathematical model of glycolysis?

I am looking for papers containing kinetic mathematical models of glycolysis, hopefully in mammalian cells (or as close as possible, say yeast). The papers I have found do qualitative analysis (...
4
votes
1answer
167 views

What are the secondary structure requirements for cell-penetrating peptides AKA protein transduction domains

Cell penetrating peptides. Cell penetrating peptides (CPPs) are a class of short amino acid sequences which are sufficient for crossing cell membranes and delivering themselves along with any ...
4
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0answers
44 views

Can we predict a person's tolerance to cold exposure during excercise?

Being an amateur athlete and student of anatomy I've always wanted to know if there is a formula for determining an unconditioned body's tolerance to cold temperatures while exercising. I know the ...
4
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0answers
237 views

Looking for a dichotomous key to identify primates

I'm looking for a dichotomous key to identify primates by physical and possibly geographical traits. Any format is fine (print, web, mobile app, etc.). Other than classroom activities and genetic ...
4
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2answers
90 views

Is arachnophobia connected to lower immunity against spider toxins?

Are arachnophobics more subceptible to toxical effects coming from spider toxins?
3
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3answers
440 views

Looking for Kelly Chibale's paper on Malaria cure

From National Geographic, there has been a lot of hype on Kelly Chibale's work from University of Cape Town on the aminopyridine MMV390048. Unfortunately, this was from an announcement from an ...