Questions tagged [medicine]

Medicine is the doctrine of prevention, diagnosis and treatment of diseases and injuries in humans and animals. Health and medicine questions are off-topic unless dealing with the biology underlying health and medicine. Please carefully explore the tour, help centre, and meta before posting health and medicine questions.

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278 views

Can upper motor neuron lesions cause hypotonia?

I have been taught that hypotonia is always caused by lower motor neuron lesions while hypertonia is by upper motor neuron lesions. However, I recently learned of an entity called central hypotonia, ...
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What ailments used to be completely fatal (or nearly so) but, now modern medicine has a treatment or cure?

My brother was a Type 1 diabetic and back in high school I did a report on diabetes. One of the things that struck me was that before 1921, type 1 diabetes was basically 100% fatal. I was wondering ...
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How do we know that mild forms of rabies are nonexistent?

Wikipedia's rabies article says: "Death usually occurs 2 to 10 days after first symptoms. Survival is almost unknown once symptoms have presented, even with the administration of proper and intensive ...
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Why is there such a large evening rise of temperature and night sweats in certain diseases like TB, lymphoma etc?

I've heard that it's got to do something with the levels of cortisol which usually dampens the effects of IL-1, but when it's night time the cortisol levels are usually low so IL-1 response is ...
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Relationship between inbreeding and sterility in humans

In general, inbred individuals tend to be at increased risk of sterility as shown in cows (Gonzales-Recio, 2007) or in leghorns (Nordskog and Cheng, 1988) for examples. I only have very quickly looked ...
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56 views

Why is free ribose not reduced to deoxyribose rather than the reduction occuring on ribonucleotides

I cannot understand why deoxyribonucleotides are not synthesized directly from deoxyribose, but ribonucleotides have to be synthesized first, and only then can deoxyribonucleotides be synthesized.
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Why is beta thalassemia major not lethal while alpha thalassemia with loss of all 4 genes lethal?

So why is beta thalassemia major with two B0 alleles not fatal in utero (despite the hemoglobin not having any B chains), while alpha thalassemia with deletion of all 4 genes encoding for the alpha ...
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121 views

Could a human become infected with rabies in such a way that even prior vaccination wouldn't stop the infection?

Given the highly persistent nature of rabies after entering the brain, I was wondering whether certain ways of exposure to this virus could be risky even for a previously vaccinated individual. I ...
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Is it theoretically possible to safely eliminate most viruses in the atmosphere, hence preemptively cure all the viral diseases? [closed]

Could we create a genetically modified virus or bacteria (with inability to mutate into something dangerous for animals) that would quickly spread all over the planet and selectively kill most of the ...
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1answer
67 views

Is hydroxyproline an amino acid? (Classification question)

So I know that hydroxyproline is created from proline via hydroxylation as a post-translational modification. I also know that proline is considered an amino acid. However, once you hydroxylize it, ...
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46 views

Which kind of drugs get absorbed through epidermis?

Some drugs such as nicotine can be administered through skin. I thought the layers of skin are designed to prevent in-flow of any chemical/germs. Not all drugs get absorbed in this fashion. So do ...
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How would a medication cause a one to maintain a different weight?

This isn’t really a medical question, I’m just really curious about this. I was maintaining weight A and then started taking a medication that brought me to weight B. While on the medication, I ...
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101 views

How having sickle cell trait would provide resistance to malarial parasites?

It's mentioned in my textbook that subjects with sickle cell trait develop resistance to malaria. I've read a few research papers predisposing involvement of macrophages and papers asserting ...
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Why are only few cigarette smokers prone to cancer?

It's tacit that only a few populace of smokers get cancer. What spares the others from it or what specifically cause cancer in those populace? See this Washington Post Article
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177 views

How does 2,3 biphosphoglycerate works to release oxygen bound to the hemoglobin?

I read on Wikipedia that 2,3 BPG binds with the deoxygenated state of hemoglobin and helps in stabilizing it. It was also written that it helps release remaining oxygen from the hemoglobin. How? ...
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170 views

Why ketoacidosis is less common in patients of Noninsulin Dependent Diabetes Mellitus?

The other day my teacher said ketone bodies are mostly formed when insulin is less and NIDDM type diabetes mellitus has less chances to grow ketosis. https://medlineplus.gov/ency/article/000320.htm P. ...
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Does avoiding medication that alleviates symptoms shorten the length of a cold?

People use over the counter (OTC) medications to relieve symptoms of the common cold. However, these symptoms are part of the immune response, right? They are driven by the body responding to the ...
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123 views

Does adenylate cyclase stimulate or inhibit acid secretion in the stomach?

I am confused about my teacher's notes. "Acid secretion is stimulated by ACh, gastrin and histamine. Histamine stimulates adenylate cyclase which increases cAMP production." When I looked this up ...
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28 views

Does using animal models for medical research also promote veterinary research on these animal types?

I have been reading about mouse models for studying inflammatory bowel diseases such as Crohn's disease and Ulverative Colitis. For example, according to this publication, a widely used mouse model ...
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49 views

Why is plasma glucose concentration not double that of whole blood?

It is known that the concentration of plasma glucose is 12% higher than that of whole blood. But since 45-50% of whole blood is red blood cells, shouldn't the plasma glucose be almost double — since ...
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1answer
37 views

Finding out the best concentration for my plant extract to be used as drug for diabetes

I am using plant extract of Ajuga parviflora and found out that it possess anti-diabetic properties by using alpha-amylase inhibitory assay. I used various concentration 250 µg/ml(29% inhibiton of ...
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2answers
132 views

Is the glomerular filtration rate, per kidney or for both?

We say in a healthy human being the average glomerular filtration rate is about 120 mL/min. Is that for both kidneys together (60+60), or just one kidney? Pardon me if this makes me sound like an ...
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169 views

Is hydrothorax considered as edema?

In _Robbins Basic Pathology 9th ed., edema is defined as [E]dema is an accumulation of interstitial fluid within tissues. Extravascular fluid can also collect in body cavities such as the ...
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1answer
155 views

Why warfarin is given as racemic mixture?

Warfarin is administered as a racemic mixture of S- and R- warfarin. S- warfarin is 3 to 5 times more potent than R- warfarin. So, what's the logic behind giving a mixture of it? Isn't administration ...
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What exactly causes SSRIs, SNRIs, and tricyclics to induce akathisia?

Such as too high neurotransmitter levels (serotonin/dopamine/other) or the method of drug delivery or some other reason? Please keep in mind I know very little about this subject, I apologize for the ...
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789 views

Why does the rabies virus have such a long incubation period?

So there was a case in India, where a man developed rabies 25 yrs after the dog bite. Source: https://www.google.co.in/amp/s/m.timesofindia.com/city/goa/25-yrs-after-dog-bite-man-gets-dies-of-rabies/...
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Is swimming pool water actually a weak topical medication?

I was inspired by this question. Given that the chlorine levels in swimming pool water are so high that they can seriously harm amphibians, it seems logical that the water should also kill various ...
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Why are vaccines a successful treatment of allergy?

As I understand the answer to Allergic rhinitis vaccine, the vaccine facilitates immune response against the antigen. Given that allergy is an overreaction of the immune system against harmless ...
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933 views

How harmful is aluminium?

I have been taught in school that aluminium is harmful for brain. Thus sour meals should not be cooked in aluminium pots and it is unhealthy to add lemon juice to tea while there is teabag in the cup, ...
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1answer
39 views

What is the mechanism behind sympathic effusion of serous cavities due to nearby abscess?

Patient with left perinephric abcess which does not ruptured have reduced breath sound that is mostly due to plural effusion revealed by CT scan which was sterile. I found this called sympathetic ...
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1answer
151 views

How might IV-saline cause kidney damage that seems to be less likely with “balanced fluids” IVs instead?

The ABC News article What's in the IV bag? Studies show safer option than saline includes: Saline — salt dissolved in water — has been the most widely used fluid in the U.S. for more than a century ...
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124 views

Why is full cell/high antigen dose pertussis vaccine dangerous for adults?

I do remember that I have read (or heard) somewhere that as a human is older, the whole cell vaccine (and high antigen dose one) has more and more adverse effects. As it is consistent with the target ...
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57 views

Could Cannabidiol steady a hand? [closed]

Can Cannabidiol be used to steady shaky or nervous hand for precision work like surgery? I have used it for shooting pool/billiards and I'm not sure if it is a placebo or it is helping? but I am ...
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What are some good examples of open-source articles in which the synergy of two medicines is demonstrated?

I am doing research on Stochastic Cooperative Game Theory (a subfield in mathematics), which I will henceforth call SCGT for convenience. In this theory, entities can work together to receive a bigger ...
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1answer
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Rabies virus mortality [duplicate]

Why rabies virus has nearly 100% fatality rate in human (see this virology blog; thanks to @iayork for the link) if not vaccinated early, even some people have survived Ebola, then why does rabies doe ...
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4answers
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Why have a placebo control group when testing a new drug if existing drugs can be used?

It is general practice to compare a new treatment against a sham treatment (placebo), and then use those results to compare efficacy of the new treatment (call it B) to an existing treatment (call it ...
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1answer
37 views

Genetics… Translocation

Can a Translocation of chromosomal parts occur between an autosome and an allosome? If it occurs in between allosomes,what could be the effect of Robertsonian Translocation between an X and a Y ...
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Embolism risk in cancer [closed]

Why is there an increased risk of embolism in any malignancy? I studied that malignancy is a risk factor for pulmonary embolism. Can someone explain me the exact mechanism under which malignancy ...
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1answer
2k views

Why cornstarch for athlete's feet?

It seems like a lot of foot (anti-odor or antifungal) powders are often based off of cornstarch (i.e., as the primary filler). But wouldn't cornstarch (which, in some places, is also a common food ...
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207 views

What happens if you intake pure magnesium? [closed]

We know that body needs a certain amount of magnesium. Why are magnesium supplements in the form of magnesium oxide, magnesium citrate, etc?
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272 views

Why do erythrocytes have no MHC1 but platelets do?

Red blood cells do not have a considerable number of MHC1 through their membranes, and that's explained by them not having a nucleus. But why do platelets have MHC1s if they have no nucleus either? I ...
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176 views

How medical studies induce cancer in lab animals?

To test the effectiveness of drugs, they are typically tested on animals. How cancer is induced in lab animals to test the effectiveness of cancer drugs?
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Can you “fight” a coma or serious illness?

In an article about the latest earthquake to strike Mexico, I read that a rescuer said to someone in a gurney, "Fight for your life, please!" I've seen similar things in TV shows and movies where a ...
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2k views

How fast can the human body temperature change?

I'm really curious about how fast can a human body temperature change? E.g. how fast can the human body temperature change when the human has fever? I'm not interested in how fast fever changes the ...
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22 views

Using Transduction to reverse Antibiotic Resistance?

Is it possible to use reverse transduction to reverse antibiotic resistance. Since antibitiotic resistance is causee by transduction of the F factor, is it possible to induce a F+ non antibiotic ...
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1answer
146 views

How does adjuvant enhance the immunogenicity of antigen? [closed]

My question is, How does adjuvant enhance immunogenicity of antigen? I just want to know deeply about it , Any suggestions will be helpful!
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2k views

What are those brown scars in the eyes? [closed]

I have recently realised that one of my friends had brown scars or marks inside his eyes. He says that he doesn't know what they are and has been there since young. What could this possibly be ? Are ...
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Placebo effect and why they work [closed]

I'm just wondering how the placebo effect works on people. If a patient is given fake drugs , how does that make him better? So what if they feel more "assured", how would that help the body immunity (...
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875 views

Why does an increased heart rate mean increased blood pressure?

Say a person starts exercising. If their cardiac volume remains the same but their heart rate increases so that the overall result is an increase in cardiac output, will their blood pressure increase ...
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336 views

How does Reissner's membrane rupture cause Ménière's disease symptoms?

In Ménière's disease, an ednolymphatic hydrops (EH) in scala media leads to a distention and, eventually, rupture of Reissner's membrane. This results in an influx of K+-rich endolymph into the Na+-...