Questions tagged [mouse]

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Number of dopaminergic neurons in VTA

Do you know an authoritative source for the approximate number of dopaminergc cells in the ventral tegmental area (VTA)? Ideally I would like to know this for mice, rats, as well as humans, but one ...
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1answer
61 views

Mouse H2 allele sequences

I've been trying to find complete sequences of mouse (Mus musculus) MHC H2 locus haplotypes for quite some time now with limited success. The EBI IMGT database has a table of mouse H2 haplotypes, yet ...
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0answers
27 views

What is the advantage of producing IgY bird's antibody instead of IgG? [closed]

Usually IgG antibodies are produced in mice. What is the advantage of producing IgY bird's antibody instead of IgG?
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1answer
462 views

Why is Mus Musculus a good model organism? [closed]

I'm reading through a number of articles that use partial hepatectomy in Mus Musculus to study the mechanisms for liver regeneration (1, 2, 3). I have no doubt that a better understanding of ...
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2answers
264 views

Inbred mice has no severe phenotype outcome?

Why does 20 generation of inbred mouse have no particular strange phenotypes, but on the contrary, when on purposely inbreed dogs or tigers for specific phenotype cause severe deformation of the bone ...
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1answer
82 views

Solid mouse (C57BL/6) WT primers

I am trying to get a good pair (or better yet, library of pairs) of primers that give me one band in WT mice (C57BL/6). Do you know where I could find such a thing? Alternatively, I thought of just ...
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2answers
783 views

At what age does the mouse skull stop growing?

Unless otherwise mandated, neuroscientific research on mice is done with ~7-week old animals. There is a sort-of mantra that at this age their skulls stop growing. However, recently, I noticed a ...
6
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1answer
966 views

In percentage, how much is the human genome (DNA) similar to the mouse genome?

Some guy argued with me against evolution theory, and he claimed that human and mice share 98% just like human and chimpanzee. I've tried to search online for a simple and accurate answer, but I ...
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1answer
352 views

What are mouse LS cells?

I have seen the term "mouse LS cell" used in several papers now, but I haven't found an explanation for the origin of these cells (for example, this paper). What are mouse LS cells? What is their ...
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1answer
2k views

Mouse Colony Software

I am looking for a good mouse colony census program that tracks the mice we have in the lab, breeding success of breeders, lineages, multiple user access, etc. Jackson labs has a program that does ...
3
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1answer
118 views

How to inhibit formation of specific antibodies (to antisera)?

Is there a way to inhibit an antibody response to a specific antigen using immunosupression? I am interested in reducing the anti-antibody formation to animal antibodies such as murine antibodies in ...
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2answers
203 views

human anti-mouse antibody

I have heard about human anti-mouse antibodies (HAMAs) and read that HAMAs neutralize murine antibodies, therefore decreasing the effectiveness of those murine antibodies. Is this true that HAMAs ...
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1answer
294 views

Does isolation have any effect upon mouse behavior?

I work with a lot of mice. I don't do any behavioral analysis, I just inject DNA or RNA and do imaging assays. However, I have noticed some effect of isolation on mouse behavior. Normally, the mice ...