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Questions tagged [neurodegenerative-disorders]

Neurodegenerative disorders are disorders characterised by progressive neuronal cell death.

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24 views

Do lychees cause encephalitis?

In India, there is a recent outbreak of this disease after many consumed lychees. Many people link this to lychee's "toxins". I'm not a biology major hence can't elaborate further on this, but here ...
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1answer
5k views

Why are prions in animal diets not destroyed by the digestive system?

According to CBC: Mad cow disease is the common name for a condition known technically as bovine spongiform encephalopathy, or BSE. [...] The only known source of mad cow disease is from animal-...
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What is it that specifically kills ALS patients?

ALS is a fatal motor neuron disease, and even though there are many different articles out there on the topic "How does ALS actually kill you?", none of them really delve deep enough into biology to ...
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1answer
103 views

Are axons capable of endocytosis?

There is evidence for the uptake of toxic substances like prions from the cell bodies of neurons via endocytosis. There is also evidence for prion deposition in white matter. But I haven't been able ...
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0answers
122 views

How much should one smoke in order to prevent Parkinson's? [closed]

There are studies who claim that nicotine has a neuroprotective effect against Parkinson's(such as this: http://www.ncbi.nlm.nih.gov/pubmed/11772120) What would be the minimum amount of nicotine(...
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0answers
55 views

Of people who develop Alzheimer disease, are those people genetically predisposed to it?

I have read a lot lately about microbiological pathogens that are found in blood vessels in the brain of patient's with Alzheimer disease (positive association). So, I am confused whether there are ...
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1answer
76 views

Why to use transgenic mice in ALS models?

In ALS mice model with mutant SOD1 - there are use of transgenic mice, with insert of human mutant SOD1. Why is that? Why not to mutate directly mice SOD1 ? In transgenic mice, after few generations ...
6
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1answer
262 views

Why does ALS start in middle age?

Amyotrophic lateral sclerosis (ALS) often starts at middle age, but I didn't find any suggestion why. Something seems to trigger the symptoms in middle age. If I am not mistaken, the sporadic ALS is ...
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1answer
5k views

Does breath-holding cause permanent brain damage?

My question is: Does voluntarily holding your breath at atmospheric pressure for a few minutes can cause brain damage? I'm talking about periods of time around 3 minutes. I've read there are some ...
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1answer
1k views

What is the mechanism behind tinnitus?

I seem to have come across two contrasting explanations for tinnitus induced by loud noises- i.e. damage to the hair cells in the cochlea. On the one hand, I have read that damage to the hair cells ...
24
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1answer
29k views

Why do adults lose hearing at high frequencies?

Children and teens can hear high pitched sounds that adults can't hear anymore. Why do adults lose high-frequency hearing?
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1answer
183 views

Congenital blindness due to retinitis pigmentosa - does it exist?

Retinitis pigmentosa (RP) patients typically become blind after a period of years in which their eye sight slowly deteriorates due to photoreceptor degeneration. Generally RP patients develop night-...
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1answer
91 views

The use of proteins in memory creation

I have very limited knowledge of how the human memory works as I think, at this time, most people do. However, I have been reading and some articles which say, and I quote the article just linked ...
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1answer
199 views

Do insomniacs yawn?

According to wikipedia, the jury is still out on the function a yawn serves. The article referenced above however writes to say Yawning most often occurs in adults immediately before and after ...
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5answers
459 views

What causes autism?

What causes autism? By this I don't mean what is to blame i.e. Vaccines, Gluten or Pharmaceuticals etc.. I mean what exactly is happening in the brain to cause the autistic behaviors such as little ...
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1answer
935 views

What factors govern the variable age of onset in Huntington's Disease?

"Huntington's disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems." As we all know, this genetic disease ...
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What does effect would Sulforaphane have on Kennedy's Disease?

Sulforaphane is a isothiocyanate found in cruciferous vegetables including broccoli and cauliflower. Its 2D structure is as follows: It's been found to serve as a histone deacetylase 6 (HDAC6) ...
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138 views

What are some of the immediate challenges to break through before finding a cure for mad cow disease?

What are the immediate challenges to break through in seeking a cure for mad cow disease? I know that mad cow disease has no treatment as of yet.