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Questions tagged [neurology]

The medical specialty involving the diagnosis and treatment of all categories of disease involving the central, peripheral, and autonomic nervous systems, including their coverings, blood vessels, and all effector tissue, such as muscle.

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How do organophosphates actually work?

The common explanation as to what the primary mechanism of action for organophosphates (and carbamates) is is the inhibition of the enzyme acetylcholinesterase and resulting buildup of acetylcholine ...
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1answer
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Neurons competing for survival

I was reading in a book that in the process of neurogenesis - when new neurons are born - neurons compete for survival. Or in other words they have to make themselves useful to the brain otherwise ...
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Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
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Would methamphetamine heal wounds, infections, and diseases?

Alright, so this sounds crazy but based on these research findings it is safe to assume that meth would allow wounds and diseases to heal faster by interleukin 6 . On the otherhand, using meth during ...
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0answers
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What phosphorylates tau protein & and what causes tau to be phosphorylated?

I want to know what phosphorylates tau protein and its 6 isoforms. I know kinases cause phosphorylation events, and in tau it can be phosphorylated in a healthy neuron in the trans conformation, but ...
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0answers
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What is the signal that indicates which neurons Schwann cells should myelinate versus which should remain unmyelinated?

Schwann cells are neuroglial cells that produce myelin in the peripheral nervous system. However, not all axons are myelinated - some will remain unmyelinated. There must be some signal that ...
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45 views

Question About the Physiology of Seizures

Absence seizures usually occur in children between ages 4 to 14 (Hopkins Hospital). Spontaneous remission occurs in 65–70% of patients during adolescence (Medicine Central). My question is what ...
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How long can one go with necrosis?

In general, when a limb dies, how long does it take before it falls off? Can you go years with a black and useless limb, or does it just.. fall off right away?
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What is methamphetamine's transport carrier across the BBB?

Which carrier protein allows methamphetamine to cross the blood brain barrier? I would assume it's SLC22 and possibly SCAMP1
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0answers
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CNS lymphatic vessels around ventricles lat et 4th?

I am searching for precise locations of the lymphatic vessels of the CNS based on the applications of the article here. However, I did not find any when having a focus on the immediate region around ...
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0answers
45 views

What happens to the brain during meditation?

I've read several experiments on the internet according to which it is possible to reach a psychedelic state without taking any psychedelic drugs like DMT, LSD and other tryptamine derivatives. It ...
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0answers
91 views

Loss of nerves in asthma

This site says: VIP [vasoactive intestinal peptide] nerves are absent in severely asthmatic subjects. Mice with targeted deletion of the VIP gene exhibit histopathologic features of airway ...
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Dorsal root fibres

How can dorsal root fibres be unmylinated though are responsible for conduction of pain and temperature? How is their conduction so fast without even being myelinated? Is presence of only one axon( ...
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0answers
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Electrode locations for neuron study in stereo EEG?

I am thinking where to put optimally depth electrodes in stereo EEG outside sulci in studying the functioning of neural transmission of N neurons over one perivascular space in rodents, mice or rat, ...
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0answers
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Is there an evolutionary reason why so many white matter tracts decussate in the brainstem and spinal chord?

From a developmental perspective, I would tend to assume that it would be much simpler for the fibers descending from (for instance) the pyramidal tracts, superior cerebellar peduncles, or ascending ...
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0answers
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How well does the event-driven DVS sensor approximate the rods of the retina?

There is a neuromorphic vision sensor that is generating some interesting research these days that is called the Dynamic Vision Sensor. One of the claims of this sensor is good approximation of the ...
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0answers
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What substances can selectively destroy certain cells?

Recently, I've watched a documentary about how, in the 1980s, people were buying and using drugs from the streets and then becoming paralyzed a few days afterwards. The drugs that they were using were ...
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Do non-human primates have mental disorders like humans?

I was at the zoo today and watched a gorilla pick at a scab on its finger, compulsively, until it started bleeding. Is this OCD or is it just a nervous thing that non-human primates do at the zoo? Do ...
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0answers
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Why Cerebrospinal fluid is not heated for VDRL?

For performing VDRL of serum , we heat serum to inactivate complement proteins which may otherwise interfere , but why don't we do same for CSF even though it too has complement proteins in it? Is it ...
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is it possible to use electroshock to temporary stop gross motor functions directly on the neural pathway?

Is it possible to modify that procedure and use it to send a small electroshock on the specific neural pathway and temporarily stop that gross motor function? When the microphone detects unwanted ...
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Why do nerve fibres rotate?

Background: Lemniscus (Latin lēmniscus, ribbon) is a strap of second order nerve fibres which twist as they ascend to the brainstem. Why do these these nerve fibres rotate? What could be the ...
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Is 7-nitroindazole neuroprotective against meth because it oxidizes peroxynitrate?

So 7-nitroindazole (7-NI) prevents methamphetamine (METH) induced neurotoxicity AND completely prevents meth induced dopamine depletion, but doesn't prevent meth induced hyperthermia. Strangely, a ...
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FitzHugh–Nagumo system with diffusion

I was studying the FitzHugh-Nagumo model with diffusion and I quite do not understand the meaning of it. If we consider the system without diffusion, \begin{equation}\label{FHN}\begin{cases} \dot{u}=...
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55 views

Of people who develop Alzheimer disease, are those people genetically predisposed to it?

I have read a lot lately about microbiological pathogens that are found in blood vessels in the brain of patient's with Alzheimer disease (positive association). So, I am confused whether there are ...
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Recovering Coma patient with theoretical full knowledge of heart function

In coma, there is the medullary depression (stage of agony). Spontaneous respiration and circulation cease i.e. vasomotor center. There is no full circulatory and respiratory support. Assume you ...
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Image formation

I have learnt that the brain provides a perception of image due to previous memory and experience. Then how does a blind person attain vision after cornea replacement?
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Does loss of dopaminergic neurons totally eliminate voluntary muscular control?

Breathing is a function that is not only autonomic, but can also be temporarily overridden and placed under voluntary control. In fact, you are now breathing manually. Now, suppose that someone has ...
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How much is the motion speed of calcium ions in ion channels and neurons?

As far as I know, calcium ions moving in a Brownian manner are responsible for the performance of neurons and neuro-transmitters. My question is, how much kinetic energy these calcium ions have and ...
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Are there toxins that cause heart attack and/or stroke in multiple individuals in short time frames?

Are there any known environmental factors that would cause more than one person to have a heart attack or stroke within a short period of time (e.g. 2-3 months) of one another? I'm particularly ...
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Is there still a convincing argument/evidence that adult neurogenesis does not exist/play an essential role in NON-Human Primates?

Adult neurogenesis in human-being is a debated topic, and will probably take several years to get resolved. I am under impression that it is relatively easier to settle the debate on non-human ...
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Does the Spinoreticular Tract end in Brainstem?

According to this book on Springer spinoreticular tract is : As the name implies, the tract originates in the spinal cord and terminates in the reticular formation (RF) in the brainstem. While most ...