Questions tagged [neuromodulation]

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How do I stimulate a neuron extracellularly, specifically the sphenopalatine ganglion

Apologies if this is too basic of a question, but I am an electrical engineer, just getting into neuromodulation/neurostimulation. For my senior project, I am trying to make a device that stimulates ...
Brian's user avatar
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How does current delivered by a neural stimulator propagate in the brain?

I have been trying to find good literature on how a stimulus current propagates through a medium that contains both gray and white matter (like the brain). Is it safe to assume that a current will ...
Moppentapper's user avatar
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What controls gut motility?

I have two different papers. One claims that gut motility is reduced by stimulation of the Opioid κ and δ receptors. The receptors are activated by Morphine and certain derivatives, specifically ...
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Gastroenteritis virus causing mutation of the Enterochromaffin cells

I am working on the solution to a worldwide problem: IBS or chronic diarrhea following a viral gastroenteritis infection. I think I have an answer. The only missing piece to the puzzle I found in a ...
DcShank's user avatar
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2 votes
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Which of the nicotinic acetylcholine receptors (nAChRs) catalyse the release of the neuromodulators mentioned below that's caused by nicotine?

Neuromodulators: acetylcholine, norepinephrine, epinephrine, vasopressin, histamine, arginine, serotonin, dopamine, autocrine agents, and $\beta$-endorphin. I am aware that agonists of the $\alpha_7 $...
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Endocannabinoid Transporters - which ones are Likely to Exist and what is the Evidence for their Respective Existence?

Endocananbinoid = Endogenous Cannabinoid or CB1 and CB2 ligands. I'm asking which endocannabinoid transporters exist and could the one answering show all the evidence for the existence of the ...
Josh Pinto's user avatar
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1 vote
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Does regulate always mean suppress when it comes to heteroreceptors?

Do heteroreceptors always suppress the release of the neurotransmitter they regulate upon their (the heteroreceptor's) activation?
Josh Pinto's user avatar
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3 votes
1 answer
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What triggers creative thought in humans?

Creativity, innovation and ideation. Is there something in the brain that makes the brain think that way, as opposed to "normal baseline". What triggers creative thought in humans?
Alex Stone's user avatar
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3 votes
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703 views

What is the relationship between Homocysteine and Norepinephrine metabolic cycles?

I've been researching neuromodulators and have taken a look at the Norepinephrine/Noradrenaline system. The diagram of biosynthesis of Norepinephrine is presented in the wikipedia article: ...
Alex Stone's user avatar
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