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Questions tagged [neurotransmitter]

Small molecules involved in the propagation of a nerve signal across the synapses.

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Does dopamine suppress serotonin production?

In a youtube video in spanish, I heard that dopamine suppress serotonin production. Is that true?
Dare to ask-I dnt mind punishm's user avatar
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Which co-transmitters are released first?

I understand that a single neuron can release different neurotransmitters depending on the frequency of its stimulation (see https://www.ncbi.nlm.nih.gov/books/NBK10818/). As the frequency of ...
Jim Doe's user avatar
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Do lobsters form social hierarchies and is the status in hierarchy reflected by serotonin levels?

In his book 12 rules for life Jordan Peterson claims that: Consider serotonin, the chemical that governs posture and escape in the lobster. Low- ranking lobsters produce comparatively low levels of ...
CuriousIndeed's user avatar
6 votes
2 answers
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Neurons: how does the brain reduce electromagnetic interference?

I read that the frequency of signal over neural ion channels in the brain can range from .19 Hz - 30 Hz at low voltage. For an interference example, AC electricity is 60 Hz at high voltage and ...
Nick's user avatar
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Vision and signal through the nervous system: Is it Frequency Shift Keying?

I have questions regarding the signal between the retina and other parts of the brain. There are two types bipolar cells which are excited by light or darkness to the retina. Question: Do these form ...
Nick's user avatar
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Impact of increased sodium conductance at a neuromuscular junction

If trans-epithelial Na+ transport were to increase at the synapse(please consider both pre and post-synaptic membrane situations) in a neuromuscular junction, how would that manifest itself? My guess ...
user1155386's user avatar
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Is Signal Transduction Unidirectional from the Stimuli to the Final Receptor?

I wonder if signal transduction in biological systems including visual, olfactory, tactile or any other biological system, is unidirectional. Suppose that $X_i$ is the $ith$ cell in the signal ...
Ali Pedram's user avatar
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3 answers
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Is there a difference between human neuron cells compared to those of other animals?

Thanks for looking. Firstly, I am nowhere near biologist, just a student, so my apologies if this isn't a "good" question. Background: So I was searching about intelligence, brains and ...
Zombie Chibi XD's user avatar
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Where are neurotransmitters secreted?

As far as I know, neurotransmitters are proteins, so they should be secreted from the cell body of the neurons. However, when I checked online, they say neurotransmitters are secreted in the axon ...
234ff's user avatar
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Using serotonin for relief from allergies

When someone suffers from an allergy, due some allergens they are given drugs like anti-histamine, adrenaline or serotonin. How does serotonin affects the body to give a relieve from the action of ...
Vaibhav Raj's user avatar
-2 votes
1 answer
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Alternative hypothesis for learning in brain beyond the hebbian rule

I was reading on wikipedia that there are exceptions to the hebbian rule, and I was curious about the possibilities of other hypotheses of how learning occur in the brain. So I would like to know: ...
Raphael Augusto's user avatar
5 votes
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How do anticholinesterase pesticides kill nematodes?

Compounds that inhibit the enzyme acetylcholinesterase are commonly used as pesticides. In animals with centralized respiratory systems controlled by the nervous system, poisoning with an ...
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Are endorphins addictive?

Endorphins are among the brain chemicals known as neurotransmitters, which function to transmit electrical signals within the nervous system. Stress and pain are the two most common factors leading to ...
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Can catecholamines degrade back into tyrosine, or, is synthesis irreversible? (in human body)

Catecholamines like dopamine, noradrenaline and adrenaline are broken down with enzymes that catalyze the reaction. Can they degrade back into tyrosine (a conditionally essential amino acid), or is ...
Leif's user avatar
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Differences between neurotransmitters and neuromodulators

According to the Wikipedia article on neuromodulation a neuromodulator can be conceptualized as a neurotransmitter that is not reabsorbed by the pre-synaptic neuron or broken down into a ...
Hans-Peter Stricker's user avatar
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How does the dopamine spike from drugs compare quantitatively to pleasurable non-drug activities?

I did find this popular press article that quotes a researcher offering the following quantification: "in lab experiments done on animals, sex causes dopamine levels to jump from 100 to 200 units, and ...
Andy's user avatar
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Where do the Ca ions that causes neurotransmitter release from synaptic bouton, come from?

I hope the information you share will help clarify the following doubts and gaps in my knowledge: Where do the Calcium ions in the influx (which then triggers the neurotransmitter vesicles) come from?...
pulkitsinghal's user avatar
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What are the chemicals in the gap at a synapse? [duplicate]

I am learning about (introductory level) biological psychology and the synapse structure came into mind. I do understand that neurotransmitters are transmitted between two neurons via the synapse ...
justadzr's user avatar
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What determines the influx of calcium ions in the voltage-gated ion channels?

Calcium channels play a crucial role in neuronal signaling by helping the synaptic vesicles to fuse through the synaptic active zone and release their neurotransmitters. My question is, at a given ...
Alex L's user avatar
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2 answers
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Are neurotransmitters part of the endocrine system?

I was speaking with a substitute teacher of mine, and we were discussing whether neurotransmitters are part of the endocrine system or not. My class just spent an entire semester on the topic of the ...
chilipepperhott's user avatar
2 votes
1 answer
2k views

What causes sodium channels to open?

What triggers the opening of sodium channels in a neuronal membrane? Is it acetylcholine that activates sodium channels in the postsynaptic membrane? Are sodium channels like receptors that have to ...
stressed out's user avatar
3 votes
1 answer
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What makes synaptic vesicle release probabilistic?

The fusion of synaptic vesicles (SVs) with the plasma membrane of the active zone (AZ) upon arrival of an action potential (AP) at the presynaptic compartment is a tightly regulated probabilistic ...
Alex L's user avatar
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Could we have endless pleasure?

Are there any studies that point out that we could have a device in the future or drug that could give us endless amount of pleasure by stimulating or blocking processes in the brain or nerve system? ...
PbxMan's user avatar
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How long does it take the neurotransmitters to diffuse accross the synaptic cleft?

Neurotransmitters get from the pre-synaptic neuron to the receptors on the post-synaptic neuron by diffusion across the gap between these two (the synaptic cleft). My question is, how much time does ...
Alex L's user avatar
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2 answers
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What material fills the synaptic cleft? Is it water?

The synaptic cleft is the gap between the pre-synaptic and post-synaptic neurons, and neurotransmitters are transferred between the neurons within this region. What substance exits in this space, is ...
Alex L's user avatar
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How do organophosphates actually work?

The common explanation as to what the primary mechanism of action for organophosphates (and carbamates) is is the inhibition of the enzyme acetylcholinesterase and resulting buildup of acetylcholine ...
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What substances can selectively destroy certain cells?

Recently, I've watched a documentary about how, in the 1980s, people were buying and using drugs from the streets and then becoming paralyzed a few days afterwards. The drugs that they were using were ...
user73910's user avatar
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Is NMDA produced in the body?

On the wiki page for NMDA it says that NMDA is a synthetic substance that mimics glutamate. So why does the body not use glutamate instead of NMDA? Also how is it possible that our body can produce ...
user3665690's user avatar
1 vote
1 answer
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Exocytosis of synaptic vesicles

I'm reading the following paper: http://jcs.biologists.org/content/123/6/819 The part I am really confused about is when they say: Exocytosis appears to use two alternative pathways: clathrin-...
user3665690's user avatar
3 votes
1 answer
366 views

How do Neurotransmitters get into the neurons?

This may be a dumb question. I'm not a Neuroscientist. I'm just trying to learn more about the brain to improve my AI learning algorithms… I understand that there are different kinds of ...
Marco Sousa-Poza's user avatar
6 votes
2 answers
192 views

Can light function as a neurotransmitter?

Any animal with an eye has photoreceptors, which are essentially light-sensitive neurons. Green algae have channelrhodopsin, which are ion channels that open and close in response to light. Clearly, ...
StarlightDown's user avatar
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Action potential frequency presynaptic neuron comared with in post-synaptic neuron/ muscle cells

I am a physicist interested in knowing how the action potential frequency in a presynaptic neuron compares with that in a) a post-synaptic neuron and b) membrane depolarisation of muslce cells, ...
Meep's user avatar
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To what extent does the distribution of nerual transmiters in the brain vary human to human?

Suppose $x$ is a position in the brain, and $n_i(x)$ is the density of neuro recepter $i$ around that point. Any given human will have some distribution of neruo recepters $n_i(x)$ through out there ...
Shane P Kelly's user avatar
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Solubility of lithium carbonate in blood

When a person with Bipolar Disorder ingests a pill of $\ce{Li_2CO_3}$ and it enters the stomach the pill cap is dissolved in the hydrochloric acid; however, when it gets absorbed in the blood how does ...
EnlightenedFunky's user avatar
7 votes
3 answers
2k views

Humans have Cannabinoid receptors. Does that mean we're meant to consume cannabis?

I know the answer is no. But what then explains the name of these receptors being specific to Cannabinoid found in cannabis? Aren't Cannabinoid receptors exclusive to Cannabinoid? Why are they named ...
yathish's user avatar
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İrreversible dopamine antagonist vs. Dopamine agonist

Can a dopamine agonist reverse the effects of an irreversible dopamine antagonist?
user57928's user avatar
2 votes
1 answer
272 views

Is every neurotransmitter receptor an ion channel?

This is a rudimentary question--perhaps the answer is well known to biologists, but is every neurotransmitter receptor also an ion channel? For example, NMDAR is a glutamate receptor and cation ...
wanderingmathematician's user avatar
2 votes
1 answer
306 views

How long does it take for a blocked dopamine receptor to be broken down by the body?

Do the blocked dopamine receptors get broken down by the body and if so how often ? In other words how long does it take for the dopamine receptors blocked by irreversible dopamine antagonists to ...
user57928's user avatar
3 votes
1 answer
528 views

Is the ACh receptor more permeable to sodium ions?

The AChR is permeable to sodium and potassium ions only and has a reversal potential of 0mV. However the Nernst potentials for sodium and potassium ions is ~ +60mV and -88mV respectively. Taking a ...
ogu01's user avatar
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2 votes
1 answer
111 views

Inhibitory effect of GABA through GABA(A) receptors

Over at Wikipedia, the following is written in the article about GABA(A) receptors: "Upon activation, the GABA(A) receptor selectively conducts Cl− through its pore. Cl- will flow out of the ...
K. Claesson's user avatar
2 votes
2 answers
14k views

difference between neurotransmitters and hormones

I have been reading a lot about neurotransmitters and hormones but what's the difference between them both or are they the same? It's been confusing for a while now. Also, why do some ...
Aisha Saif's user avatar
6 votes
2 answers
721 views

Can acetylcholine leak away from the synapse and cause spasms?

I am currently studying Pharmacology and a question came to mind. We know that Acetylcholine is used as a neurotransmitter in the neuromuscular junction, both Sympathetic as Parasympathetic, but as I ...
Mateus Gutemberg's user avatar
-1 votes
1 answer
69 views

How outside signals creates different chemical composition in the brain? [closed]

Scenario A: I am walking down the street and my phone rings. I answer and I am told that my ticket that I registered last week was lucky and I won million EUR. Scenario B: I am walking down the ...
Vy.Iv's user avatar
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3 votes
1 answer
91 views

Confusion about the construction of the rat's mental map

I'm reading the article "A Topological Paradigm for Hippocampal Spatial Map Formation Using Persistent Homology" by Y. Dabaghian, F. Mémoli, L. Frank, G. Carlsson I try to understand the following ...
palio's user avatar
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1 answer
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Does GABA help or hinder anxiety?

This article https://www.prnewswire.com/news-releases/smartphone-addiction-creates-imbalance-in-brain-300558945.html Says both The researchers performed MRS exams on the addicted youth prior to ...
Chloe's user avatar
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1 answer
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Does orgasm cause a dopamine crash?

There's some theory around that orgasm will cause a dopamine surge and drop, and that this can lead to a period of low mood or depression. A come down. Is this true, does orgasm have a negative ...
Jimmy Widdle's user avatar
4 votes
1 answer
528 views

Why does excess dopamine activity in the pleasure centers results in less pleasure in schizophrenics?

According to the dopamine hypothesis of schizophrenia, there is an excess of dopamine in the mesolimbic pathway (nucleus accumbens), and this contributes to the positive symptoms of schizophrenia. I ...
soeci92's user avatar
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1 vote
1 answer
734 views

Which function do nicotinic receptors have in the periphery?

I came across this question today, it says: Nicotinic receptors stimulation is directly responsible for ….... I should fill the spaces by one of the following choices: Increasing the excitability ...
Asmaa's user avatar
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5 votes
1 answer
1k views

Why do classic psychedelics not cause withdrawal, despite high tolerance?

"Classical" psychedelics, such as LSD, DMT, and Mescaline, are serotonin agonists that cause hallucinogenic effects. They are notorious for having rapid tolerance, such that after consuming such ...
Daniel Grover's user avatar
2 votes
2 answers
457 views

Where does the initial action potential come from?

When talking about action potentials we say that previous neurons caused an action potential in this neuron and that this neuron's action potential caused the same in further neurons. But what is the ...
Marko Kevac's user avatar