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Questions tagged [neurotransmitter]

Small molecules involved in the propagation of a nerve signal across the synapses.

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15 votes
4 answers
9k views

Is there a correlation between total neurons and intelligence?

Thanks for looking. First off, I am not a biologist, just a curious layman, so I apologize in advance if this isn't a "good" question. Please don't downvote me into oblivion. I read today ...
Matt Cashatt's user avatar
4 votes
3 answers
1k views

Mechanical cause of loss of consciousness

Consciousness is an electrical and chemical interaction in the brain, caused by neurons firing and chemical interactions. How does a mechanical "force" cause this to stop working? i.e. How does a ...
Laurence's user avatar
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8 votes
2 answers
3k views

How does the brain know where a signal came from? What is the addressing system

I am an electronic engineer so I am thinking about this from an electronics outlook. How does the addressing system work, As I see it, the nervous system is small parallel branches attached to larger ...
Shasam's user avatar
  • 83
3 votes
2 answers
1k views

What material fills the synaptic cleft? Is it water?

The synaptic cleft is the gap between the pre-synaptic and post-synaptic neurons, and neurotransmitters are transferred between the neurons within this region. What substance exits in this space, is ...
Alex L's user avatar
  • 131
1 vote
0 answers
64 views

Visual maps of the neuronal membrane

There are lots of visual maps of the brain as a whole, especially the cortex, that show the distribution of "features" over a two-dimensional map, e.g. the Brodman areas (their morphology and their ...
Hans-Peter Stricker's user avatar
11 votes
2 answers
389 views

Understanding the brain: how are neurotransmitters released in the brain?

I have a basic knowledge of how neural networks work. A potential difference is created that forces sodium, potassium, chloride, and calcium ions to flow which carries an electrical signal to the end ...
Dirac's user avatar
  • 111
4 votes
2 answers
815 views

Could an action potential produce few or more neurotransmitters based on the stimulus received?

I reckon that if you would be able to widen the AP width, it would produce more neurotransmitters in that larger time interval. Is that correct? Or does the neuron have a standard amount of ...
kalfasyan's user avatar
  • 385
3 votes
2 answers
992 views

What is the difference between neurotransmitters acting as neurotransmitters and hormones?

My main confusion is what differentiates the action of a transmitter substance as a neurotransmitter and as a hormone. For example, when norepinephrine is being talked about as transmitter substance ...
EMMs2008's user avatar
  • 265
3 votes
3 answers
3k views

Is there such thing as "half-life" of dopamine?

If a dopamine is released at T=0 and binds to receptor D2, what determines the time when the concentration of this neurotransmitter bound to the receptor reaches half of the original concentration? In ...
Alex Stone's user avatar
  • 6,515
3 votes
1 answer
214 views

Do serotonergic (5-HT2A-mediated) psychedelics elicit stimulant effects?

I know that 5-HT2A partial agonism is the key mechanism of action of serotonergic psychedelics but I also know that some research (e.g. the selective (no activity on any other known receptor sites) 5-...
Josh Pinto's user avatar
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2 votes
1 answer
306 views

How long does it take for a blocked dopamine receptor to be broken down by the body?

Do the blocked dopamine receptors get broken down by the body and if so how often ? In other words how long does it take for the dopamine receptors blocked by irreversible dopamine antagonists to ...
user57928's user avatar
2 votes
1 answer
107 views

Why do SRIs help in serotonergic neurotransmission?

Serotonin reuptake inhibitors (SRIs) block the action of the serotonin transporter (SERT) which, according to Wikipedia, leads to an increase in serotonergic neurotransmission. Now this book ...
vauge's user avatar
  • 279
2 votes
2 answers
1k views

Resting and action membrane potential..?

In the resting membrane potential of neurons the inside of membrane is kept negative and outside of membrane is kept positive by the utilization of energy through Na-K Atpase pump, While during action ...
katherinebridges's user avatar