Questions tagged [noncoding-rna]

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How to differentiate transportable element and non-coding RNA in genome?

I am searching for unannotated non-coding RNA in my genome at the same time i want to omit the transposable element from my genome. My sequencing libraries are paired-end and i am searching in the IGV ...
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1answer
172 views

Why does a cell need siRNA?

My question is about small non-coding RNAs. miRNA and siRNA are both known for mRNA regulation. miRNA can both transcriptionally inhibit and degrade mRNA by cutting it. For inhibition just a small ...
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1answer
114 views

What is the difference between alarmones and riboswitches

An Alarmone is an intracellular signal molecule that is produced due to harsh environmental factors. They regulate the gene expression at transcription level. A riboswitch is a regulatory segment of a ...
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Eukaryotic equivalent of bacterial tmRNA

According to this Wikipedia article, tmRNA is only found in bacteria, with its purpose being to “rescue stalled ribosomes”. This brings me to the question of is there a eukaryotic equivalent of this ...
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2answers
161 views

Is spliceosomal RNA called snRNP or snRNA? [closed]

I have been reading articles by various sources, and they seem to interchangeably call the U1/U2/U4/U6 compounds involved in RNA splicing snRNPs as well as snRNAs. This confuses me deeply. They must ...
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1answer
459 views

Why is Mus Musculus a good model organism? [closed]

I'm reading through a number of articles that use partial hepatectomy in Mus Musculus to study the mechanisms for liver regeneration (1, 2, 3). I have no doubt that a better understanding of ...
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1answer
278 views

Where does tracrRNA comes from? [closed]

I'm talking about CRISPR system. I know the crRNA is transcribed from the palindromic repeat and the "spacer" but I don't know where the tracrRNA comes from.
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1answer
238 views

Which are the best programs to analyze circular RNA?

Hello I'm just started with bioinformatics and I would like to know which programs are best for the task of finding circRNA (circular RNA) in sequences of tissues and different cellular types. I have ...
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non-coding RNA modelling in silico

I've been trying to model a non-coding RNA molecule which binds to a RNA binding protein. I found the DNA sequence for ncRNA from NCBI. I did not find the RNA seq of the same. Hence my doubt is, ...
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1answer
404 views

Are there parts of DNA that do not have genes?

A question in my genetics class is "Are the number of genes proportional to the genome size?" The answer is "no," and is it because the genome is the entirety of all the DNA in an organism, but that ...
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1answer
82 views

Can ncRNA convert to coding RNA/mRNA by mutations?

DNA has transcribed into RNA (Non-coding). Can this RNA mutate and become a Protein-Coding one/mRNA? Have there been any such instances reported by scientists?
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What is meant by “Expression” of Non-Coding RNA?

I was having a look at lncRNAdb and its help says: The ENCODE project gene annotation list, GENCODE, has predicted that the human genome contains 14,470 lncRNAs whereas only a small proportion of ...
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Small non-coding RNA (sRNA) vs. micro RNA (miRNA)?

What are the differences between micro RNAs (miRNA) and small non-coding RNAs (sRNA)? Are these two terms used interchangeably?
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3answers
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Are non-coding RNAs introns?

I am slightly confused as to what part of the genome codes for non-coding RNAs. Is it the introns? This would make sense to me as to why they are not transcribed as the introns are not transcribed. Or ...
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3answers
432 views

Are some non-coding RNA spliced?

Are some non-coding RNA spliced like mRNA? I tried to find some information but I don't find anything...