Questions tagged [noncoding-rna]

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How frequent are transposons in action? [closed]

A transposable element (TE, transposon, or jumping gene) is a DNA sequence that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic ...
3 votes
1 answer
99 views

Difference between LIGR-seq and PARIS methods

I would like to reuse a dataset produced by LIGR-seq for ncRNA secondary structure prediction in the style of PARIS method. At ...
1 vote
1 answer
49 views

Where in the cell does this enhancer RNA knockdown take place?

In Pneuli et al 2015, they knock down an enhancer RNA using RNAi, testing whether it is a mere byproduct or whether it has a key role in the enhancer's function. They find their system works: the ...
0 votes
1 answer
37 views

Are pseudogene counted as a subtype of long non-coding RNA genes?

Are pseudogenes regarded as a subtype of the genes for long non-coding RNAs? I could not find the answer to this question in an internet search.
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1 vote
1 answer
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Why does a cell need siRNA?

My question is about small non-coding RNAs. miRNA and siRNA are both known for mRNA regulation. miRNA can both transcriptionally inhibit and degrade mRNA by cutting it. For inhibition just a small ...
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1 vote
1 answer
138 views

What is the difference between alarmones and riboswitches

An Alarmone is an intracellular signal molecule that is produced due to harsh environmental factors. They regulate the gene expression at transcription level. A riboswitch is a regulatory segment of a ...
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1 vote
0 answers
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Eukaryotic equivalent of bacterial tmRNA

According to this Wikipedia article, tmRNA is only found in bacteria, with its purpose being to “rescue stalled ribosomes”. This brings me to the question of is there a eukaryotic equivalent of this ...
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0 votes
2 answers
176 views

Is spliceosomal RNA called snRNP or snRNA? [closed]

I have been reading articles by various sources, and they seem to interchangeably call the U1/U2/U4/U6 compounds involved in RNA splicing snRNPs as well as snRNAs. This confuses me deeply. They must ...
1 vote
1 answer
646 views

Why is Mus Musculus a good model organism? [closed]

I'm reading through a number of articles that use partial hepatectomy in Mus Musculus to study the mechanisms for liver regeneration (1, 2, 3). I have no doubt that a better understanding of ...
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0 votes
1 answer
389 views

Where does tracrRNA comes from? [closed]

I'm talking about CRISPR system. I know the crRNA is transcribed from the palindromic repeat and the "spacer" but I don't know where the tracrRNA comes from.
1 vote
1 answer
258 views

Which are the best programs to analyze circular RNA?

Hello I'm just started with bioinformatics and I would like to know which programs are best for the task of finding circRNA (circular RNA) in sequences of tissues and different cellular types. I have ...
1 vote
0 answers
37 views

non-coding RNA modelling in silico

I've been trying to model a non-coding RNA molecule which binds to a RNA binding protein. I found the DNA sequence for ncRNA from NCBI. I did not find the RNA seq of the same. Hence my doubt is, ...
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1 vote
1 answer
693 views

Are there parts of DNA that do not have genes?

A question in my genetics class is "Are the number of genes proportional to the genome size?" The answer is "no," and is it because the genome is the entirety of all the DNA in an organism, but that ...
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0 votes
1 answer
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Can ncRNA convert to coding RNA/mRNA by mutations?

DNA has transcribed into RNA (Non-coding). Can this RNA mutate and become a Protein-Coding one/mRNA? Have there been any such instances reported by scientists?
0 votes
2 answers
121 views

What is meant by "Expression" of Non-Coding RNA?

I was having a look at lncRNAdb and its help says: The ENCODE project gene annotation list, GENCODE, has predicted that the human genome contains 14,470 lncRNAs whereas only a small proportion of ...
3 votes
2 answers
2k views

Small non-coding RNA (sRNA) vs. micro RNA (miRNA)?

What are the differences between micro RNAs (miRNA) and small non-coding RNAs (sRNA)? Are these two terms used interchangeably?
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10 votes
3 answers
2k views

Are non-coding RNAs introns?

I am slightly confused as to what part of the genome codes for non-coding RNAs. Is it the introns? This would make sense to me as to why they are not transcribed as the introns are not transcribed. Or ...
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6 votes
3 answers
466 views

Are some non-coding RNA spliced?

Are some non-coding RNA spliced like mRNA? I tried to find some information but I don't find anything...