Questions tagged [nucleic-acids]

Polymers/Oligomers of mononucleotides. Nucleotides are composed of heterocyclic bases such as Adenine, Guanine, Thymine, Cytosine, and Uracil linked to a backbone moeity such as ribose (RNA), deoxyribose (DNA), N-(2-aminoethyl)-glycine (PNA), etc. These monomers are usually linked by phosphodiester bonds as in the case of DNA and RNA but can be other bonds such as peptide bonds in the case of PNA.

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Gene located on Which strand? Want reference. [duplicate]

Update: Initially my question (below) was appropriately marked as duplicate/overlapping with two other questions; This and this ; among them a specific part of an answer of the second duplicate/...
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How sterile is sterile when working with nucleic acids to prevent contamination?

I am reading up on preparatory work on working with nucleic acids and a lot of the instructions speak on excessive procedures on cleaning environments with high %ethanol and making sure the equipment ...
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Does DNA react in all of the ways most other acids do?

As I understand it from my basic chemistry, there are some fundamental reactions that exist between any acid and other substances for example acid-base reactions that form a salt, and the existence of ...
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Why don’t different organisms have nucleic acid genomes containing different bases and sugar?

All organisms contain genetic material. Be it DNA or RNA, both of them have a fixed pentose group (deoxyribose and ribose). Also they contain the same types of nitrogenous bases, Adenine, Thymine(or ...
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What could I call such nucleic-acid-Sequence? A sort of palindromic sequence? is there any term called mirror repeat?

5'... ATGCC|CCGTA ...3' 3'... TACGG|GGCAT ...5' or say 5'... AAGT|TGAA ...3' 3'... TTCA|ACTT ...5' or in generalised way; on each strand; ABCDEF|FEDCBA Is there any terminology for such-sort ...
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Want reference for a convention

This answer to another question satisfactorily answer one of my major confusion. The convention is that in indicating any sequence feature† in a protein-coding gene on double-stranded DNA, a ...
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For how long and how cold should I perform ethanol/isopropanol precipitations of RNA or DNA?

Precipitating nucleic acids using either isopropanol or ethanol is a very common operation, and I've read some very different protocols on the duration and temperature the precipitation should be ...
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What is the name of the bond between phosphate and the sugar in a nucleotide?

I am slightly confused about what the name of the bond is between the phosphate and sugar within a nucleotide. All my research comes up with is a phosphodiester bond being the backbone of DNA. But ...