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Questions tagged [nucleotide]

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Chemistry of phosphodiester bond formation by DNA polymerase

As I'm teaching General Biology to my college students, I realized that I don't fully understand how a 3-P nucleotide like ATP is broken down to be incorporated into DNA during replication. How does ...
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1answer
31 views

Are there interesting biomolecules consisting of chains of nucleotides that present multiple bond?

Watson-Crick bonds guanine-cytosine and adenine-thymine helically shape DNA. If I understand correctly, a sequence in only two of the nucleotides, for instance TGGTGTGGGTG ... would determine the dual ...
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Why can nucleotides be only added in the 5' to 3' direction? [duplicate]

In semi-conservative replication, why is it that DNA polymerase joins nucleotides in a specific direction?
3
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1answer
407 views

What is the difference between nucleotide polymorphism (θ) and nucleotide diversity (π)?

In my population genetics book (see reference at bottom) they define them as: Nucleotide polymorphism (θ): proportion of nucleotide sites that are expected to be polymorphic in any sample of size 5 ...