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Questions tagged [orf]

In molecular genetics, an open reading frame is the part of a reading frame that has the ability to be translated. An ORF is a continuous stretch of codons that may begin with a start codon and ends at a stop codon.

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Why are there six reading frames if only one strand of DNA is referred to as the ‘coding strand’?

We need to consider six reading frames when considering the potential of DNA to encode protein (three frames for each strand). But only one strand is transcribed into RNA — the so-called coding strand....
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How to determine the most likely reading frame of a DNA sequence?

This question is from a past exam paper for an introductory bioinformatics module. I'm a computer scientist doing biology for the first time. "A short bacterial gene has been sequenced, giving the ...
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