Questions tagged [pain]

Tag for questions pertaining the sensation of unpleasant sensory and emotional experiences associated with actual or potential tissue damage.

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Why does it take 24 hours for tendons to give feedback on whether the loads they received were excessive?

I heard in this interview of Jill Cook (tendon researcher) on https://youtu.be/GKkSp-TlofI?t=230: Tendons talk to you 24 hours later. So what happens if if I put load on a tendon today, it will ...
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0answers
15 views

Why are isometric contractions more analgesic than isotonic contractions for tendon pain?

According to a randomized clinical trial {1}, isometric contractions are more analgesic than isotonic contractions for tendon pain. The explanation they give is as follows: The antinociceptive ...
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0answers
29 views

How do painkillers prevent shock?

I was reading about the Placebo effect and came across this little story: The roots of the placebo problem can be traced to a lie told by an Army nurse during World War II as Allied forces ...
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1answer
26 views

How do NSAID's work and what are the differnces between COX-1 and COX-2? [closed]

NSAID's work by slowing down the COX enzym, but how do does enzymes cause pain? because I've read that they're also needed for the body and do "good" things.
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Sea Urchin Pain

Are sea urchins theoretically able to feel pain? They have output and input organs which would make them "vulnerable" to feel pain but on the other hand, they don't have brains. I was wondering if ...
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1answer
39 views

Does a severed limb/finger experience pain after its separated?

If a person ends up with a severed finger will that finger, after falling off, experience any pain and start writhing? Can a limb kind of have a mind of its own for a few more seconds after separating ...
7
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1answer
117 views

Does spinal cord have pain receptors?

I understand that the brain itself does not have pain receptors, so when the brain is damaged or cut, there is no experience of pain. For example, surgeons can operate on the brain while a patient is ...
0
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1answer
415 views

What part of the body holds the most pain receptors?

What part of the body holds the most pain receptors or is likely to cause someone to feel the most intense pain? I thought it was the eyes but I can't find that source anymore.
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3answers
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Do oysters feel pain?

Do oysters feel pain when you bite into the inside, or when you crack open the shell? I tried google searching it to no avail. When you bite inside the oyster or when you break the shell to open the ...
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0answers
97 views

Do muscles and connective tissue have different types of pain receptors?

I assume that muscles have pain receptors ("nociceptors"?) that fire when the muscle is under excessive strain or even tears or becomes injured. I also assume that similar pain receptors exist for ...
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1answer
38 views

Results of self-administration study about pain in honeybees?

There research on nih.gov about ability of bees feel pain. But I can't understand their conclusion. Could you provide necessary excerpts here from those study so it would be clear what conclusion they'...
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Pain and Angina Pectoris

What causes pain in an angina pectoris? Ok, heart muscles may lack oxygen, but what is the role of pain here? Is it being beneficial? I'd like to know the physiological process of induction of pain ...
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1answer
120 views

Is it the theory of the 5 senses obsolete? [closed]

An enigmatic topic in traditional science was labelled as the mystery of the 5 senses, and how to best group senses by type. Is that theory now meaningless? Do Scientists still agree that that ...
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3answers
5k views

Do lobsters possess a nervous system to feel pain?

I was reading an article, which it mentions that lobsters do not have a nervous system: Lobsters have very poor eyesight and no nervous system. They walk slowly on the sea floor but are capable ...
2
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2answers
94 views

At what stage is the nervous system developed enough to interpret neuronal signals as 'pain'?

According to this article in Live Science, one of the reasons the fetus can't feel pain until 19 weeks is because the nervous system isn't fully developed. But according to this article, the heart ...
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0answers
36 views

Where does the pain from headaches come from [duplicate]

I may be wrong but I have always thought that the brain doesnt have any nerve endings, so why is it we get headaches and where does this pain come from? I have heard lack of sleep, hydration or ...
1
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1answer
82 views

What makes a rotator cuff tear symptomatic in humans?

The majority of rotator cuff tears is asymptomatic {1}. What makes a rotator cuff tear symptomatic or asymptomatic in humans? References: {1} Minagawa, Hiroshi, Nobuyuki Yamamoto, Hidekazu Abe, ...
3
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1answer
136 views

Why is burn feeling 'slower' than touch?

When you touch a hot object you first feel the touch and only after a second you feel the burn too, and if you detach your skin from the object the burn feeling continues for few seconds. I remember i'...
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0answers
227 views

Why are interneurons needed in the spinal cord for polysynaptic reflexes and somatosensory tracts to the brain?

The single explanation I found for the polysynaptic reflex is that the interneuron diverges into more pathways, such as the efferent motor neuron, the inhibitory neuron to the opposite extensor muscle,...
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1answer
179 views

Why pain caused by blunt objects vanish after some time and return at the event of touching?

Background When any bone/muscle of body is hit badly by a blunt object, it hurts pretty bad of course for some time. But, after some time the pain goes off completely or to some extent. Then, if we ...
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0answers
368 views

Why does crippling pain exist? [closed]

Some kinds of trauma can cause pain so severe that it makes you unable to move or do anything at all. It may put you out of action and unable to help yourself because of how excruciating it is. ...
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0answers
117 views

Is there an evolutionary advantage associated with migraine? [duplicate]

I have read Wikipedia article on Genetics of migraine headaches and I don't buy it Because genetics influence susceptibility to migraine, it can be shaped by evolution. Fitness-impairing ...
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4answers
3k views

Is it possible to feel pain in some part of a body, but the pain “feeling” is introduced somewhere else?

Is it possible to feel pain in some part of a body, but that the cause of the pain is situated elsewhere in the body? For example, somebody feels pain in his toe, but it turns out that this pain is ...
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0answers
75 views

Why is a wound much more painful when damp?

Why is a wound much more painful when damp? This is a very strange phenomenon. For example: I have a little wound, not painful at all. But, when it is just damp, it is much painful.
17
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2answers
2k views

What is the cause that angina pectoris is felt in your left arm?

When someone has heart problems sometimes they feel pain in their left arm. But why is the left arm painful?
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0answers
285 views

How does lactic acidosis lead to pain?

I come from Physics, not biology. My understanding is that without sufficient oxygen present, the Krebs cycle terminates in lactic acid formation for the body to later continue the reaction when ...
20
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1answer
15k views

Is it painful for the hen to lay eggs?

My little son just asked me this question. His mother used to complain about the excruciating pain she suffered when she gave birth to him. He is a compassionate kid and wonders whether the hen goes ...
2
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1answer
92 views

Reseach on feeling pain of other people

I'm more of a tech than bio kind of guy, but I have read and learned a lot alongside of my girlfriend's education. Which is very interesting!! Currently I want to investigate : people claiming to ...
7
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1answer
444 views

What stimulates a nociceptor?

For instance, when pressure is applied to the skin, what determines how much pressure results in nociceptor stimulation. And when a sharp object pierces the skin, why is pain, rather than simply touch,...
4
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1answer
976 views

What causes the pain when a bone fracture is healing?

Why does a fracture still hurts when it is healing? I understand the pain at the beginning - the bone is not in its place, there is a pressure against the nerves, also the swelling pushes the nerves ...
2
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1answer
103 views

Why does mud therapy work by some pain related diseases?

Apparently, some users here agree there is no ion exchange through the skin. Mud therapy has some therapeutic effect for pain related diseases. As an anecdotal example, I experienced pain relief by ...
5
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1answer
138 views

How does Tylenol relieve pain without making me drowsy?

So I have a crown that popped out and has been killing me, I've lived on a steady diet of Tylenol since it popped out. I've noticed that aside from killing most of the pain from the tooth, the tylenol ...
2
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1answer
1k views

Most painless method for killing insects

I'm planning on having a small farm of crickets or grasshoppers. I would like to cause them as little suffering as possible, so I'm wondering what is the most painless way to kill them? So far, the ...
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1answer
209 views

Can someone die from pain? [duplicate]

I'm a CNA and I just got home from a very long day at work. I just started this job and I got hurt at work last night which made me wonder can enough pain cause death (without suicide)? I think the ...
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1answer
1k views

How is pain induced by blunt and sharp objects?

Normally, when something touch you, you won't feel pain. With a great force "touching" you, you will feel pain. However, if something that is spiky makes contact with you, you will feel pain. So, how ...
4
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1answer
394 views

Why isn't the upper limit of pain lower in humans?

From what I understand, pain is an useful mechanism that signals us that something is not quite right with our body (in particular, we're under attack). It's good - it alert us and tells us that we ...
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0answers
1k views

Skin extra sensitive to heat after burn

I just got my finger burnt (first degree burn $\Rightarrow$ I didn't even bother to bear the wound). It didn't hurt much, even when I pressed the wound. However, when exposed to heat (hot water, but ...
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2answers
301 views

If one endures the same form pain over a long period of time, would the pain begin to lose intensity?

Metaphorically thinking, if one endured the pain of constant burning for decades, would the pain slowly lose its strength?
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1answer
206 views

Normal death experience [closed]

Consider a natural cause of death (no car accidents etc) - Is it true that death is generally preceded by suffering? In other words, are we destined to experience the most severe suffering we could ...
5
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1answer
81 views

Can nociceptors die because of too much mechanical stress?

In martial art people hit their body (e.g., with small bean bags) to become more insensitive to pain. Can the sensory neurons die during this procedure? I think this is just an urban legend. Instead, ...
2
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1answer
4k views

What is the distance between the sciatic nerve and the colon at the closest point?

Is it possible that a full colon impinges on the sciatic nerve? Is there anything that physically separates the sciatic nerve from the colon?
4
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2answers
575 views

Does suffocation pain involve nociceptors?

I never suffocated myself so not entirely sure, but when you suffocate, it's painful, right? But of course different kind of pain than being injured or sick. What I'm wondering is, if the "painful" (...
4
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2answers
202 views

Does the body have a gate control for pain

I understand it is not the most accurate source but I recall a House episode where he claimed the body had a control mechanism for pain in which only the most painful thing was felt. Is that true? and ...
7
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1answer
19k views

What's a mouth ulcer/canker sore “made of”, and why do they develop?

Mouth ulcers are red/white rings with a crater. They are sore and last for 7-10 days. What I want to know is what they are 'made of' - i.e., what is the ring filled with, and why is the centre crater ...
3
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3answers
355 views

Swapping genes?

So, gene therapy is to take out a gene, correct its mutation, and put the corrected one back into the organism, right? Is it also possible to take out a gene from an organism and put in a totally ...
3
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2answers
282 views

Is there a specific mechanism for the delivery of pain medication?

For example, when one takes aspirin or ibuprofen does the chemical get dispersed to all pain receptor? My question really is, how does the chemical know where to target in the body? I figure wherever ...
5
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1answer
148 views

How do we share pain?

When somebody else tells me about his or her itching or pain in some specific body part, I sometimes begin to feel similar feelings. I can think of about three explanations: I feel pain all over my ...
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2answers
610 views

How can we know or measure pain in animals?

Is there any standard way to know how much pain an animal feels when it gets hurt like when a bird loses it's wing or hen when killed etc. All pain sensation points? Hey I'm new to biology. :)
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1answer
2k views

Redheads and pain receptors

I remember reading this in a biology textbook, and decided to do a little digging. Redheads have a lower sensitivity to some pain and a higher sensitivity to other compared to people of other colored ...
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1answer
504 views

Do people with congenital analgesia feel cold?

There are a few diseases that cause an insensitivity to pain. This question asks about the relationship between the cold and pain, which got me thinking: Is shivering a response driven by the ...