Questions tagged [pedigree]

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Is it tautological that all living humans descended from a single male and single female human ancestor?

Many popular science articles cite high sequence conservation of mitochondrial DNA and the Y chromosome among living people as evidence that all humans are descended from a single male and single ...
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Assessing carrier Risk

susan has been found to be a carrier of Tay Sachs. what is the risk that her maternal aunt is also a carrier if we don't know her parents status?
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2answers
607 views

How can i confirm that the given pedigree chart is of an autosomal dominant trait?

This image is from the NCERT textbook. In diagram A, which represents an autosomal dominant trait, I found out that autosomal recessive inheritance also satisfies the pedigree. Yet, the NCERT text ...
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How do you find probabilites of carrying an X linked recessive disease in a blank pedigree given only one phenotype?

In the above pedigree, the black square indicates the male affected with Hemophilia which is a X-linked recessive trait. What is the probability that the proposed child, which is a male (indicated as ?...
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2k views

Pedigree Probability, Autosomal Recessive Trait

So, I thought I understood how to calculate the probability for a pedigree, until I came across this answer in my textbook. The question is: what is the probability the offspring of IV1 x IV2 will ...
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Measure of relatedness between two animals

So I am aware there is such a thing as inbreeding coefficient which is a number allocated to an individual as a result of taking the average of it's parents' inbreeding coefficient. (Note that I am ...
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2answers
533 views

Does the given pedigree show a Y-linked dominant trait?

I think that since every generation has males affected only, the trait must be Y-linked. Also, since every generation expresses the trait, I think it should be dominant. However, the answer key says ...
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2answers
986 views

Probability of carrier for recessive trait given parents are carriers and sister affected

I'm trying to understand more about inheritance of an autosomal recessive trait that runs in my girlfriend's family. How could I start looking at this? My girlfriend's sister, C, is affected with a ...
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1answer
1k views

Can someone help me with this Pedigree Analysis?

$\text{So... here is the given pedigree chart:}$ My question is ... whether this is an autosomal or a X-linked recessive trait. The book I was following gave me this info: My Attempt: Looking at ...
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1answer
95 views

Why can't the mutation for this simple pedigree be X-linked recessive?

http://ocw.mit.edu/courses/biology/7-012-introduction-to-biology-fall-2004/exams/finalprac.pdf For question 7a on pages 10-11 of the above link, why can't the mutation be X-linked recessive? The ...
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1answer
372 views

Concept and analysis of Pedigree

Pedigree analysis is a process of establishing a virtually correct inheritance pattern of a genetic condition in a proband's family. I call it virtually correct because in many a cases we assume the ...
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1answer
3k views

How to recognise the type of allele by pedigree analysis diagrams? [closed]

It was said that this interference pattern is due to dominant allele. I fail to see that. In general how to recognise the type of allele by pedigree analysis diagrams?
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What does a diamond symbol actually mean in pedigree? [closed]

Does it mean a person who is neither a male or a female, a homosexual or an individual whose sex is unspecified?