# Questions tagged [population-genetics]

Questions related to the study of the distributions and changes of allele frequency in a population.

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### Hardy-Weinberg Equilibrium Test Result for Merged Genotypes

I was curious if two populations are in Hardy-Weinberg Equilibrium (HWE), and if they are merged, then what happens? To find out, I considered populations from the 1000 genome project data. For ...
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### Calculate expected heterozygocity using Wright's F statistics (here, FIS)

I try to better understand Wright's F statistics. In general, there are many derivations and many interpretations, and in books, the parameters are called differently, that's why I am struggling. More ...
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1 vote
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### Are there two different senses of the word 'heritability' in use?

Target Height as Predicted by Parental Heights in a Population-Based Study states: The heritability value was taken as the regression coefficient between final height and midparental height Is this ...
101 views

### Expected number of SNPs in a sample of size k

Consider a Wright-Fisher population of constant size $N$. We sample $k$ haplotypes in this population. What is the expected number of SNPs? I think the answer should be in Watterson (1975) but it ...
1 vote
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### Datasets for Genetic Diversity of Species Across Geographical Distribution

I'm carrying out some research on applying machine learning methods to ecology and conservation. I'd like to know: are there some datasets on genetic diversity across geographical positions? ...
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### Initial population when I count backwards?

My question deals with the number of ancestors it took to produce me: --> To produce me, it took 2 people (my parents) = ($2^1$) people = 2 --> One generation further included = ($2^1 + 2^2$) ...
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### Bottleneck in population that is already experiencing inbreeding depression

What would be the result when a population experiences a bottleneck, while already manifesting inbreeding depression? I only found this article and it suggests that the inbreeding depression would ...
194 views

### Understanding ancestry testing mathematically

Forgive me if this question has been asked here before, because it is something which should be very easy to find, but I can't seem to find an answer no matter where I search. The question is simply ...
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### Is there a term for a sequence of genomes for a family?

Suppose that I am following how a "familial" genome changes throughout generations. That is, I have the genome of a grandmother, father, and daughter, and my objective is to see how the ...
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### How does an engineered supressive Lethal (when present in 2 copies) gene drive spread through a population until causing population extinction?

I understand that at the molecular level a CRISPR mediated gene drive works by copying the altered gene (and the drive containing CAS enzyme, and guide RNA) into the other chromosome containing the ...