Questions tagged [recombination]

The process of breaking and recombining strands of DNA.

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17
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2answers
14k views

Genetic linkage greater than 50 centimorgans

Classically, the linkage between two loci can be measured in centimorgans (cM), which represents the percent chance that these two loci will recombine an odd number of times (generating a recombinant ...
14
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3answers
20k views

Why doesn't recombination occur in male Drosophila?

"Males do not show meiotic recombination, facilitating genetic studies." For a while I have known that this phenomenon occurs, this quote comes from the Wikipedia page on Drosophila melanogaster, and ...
5
votes
3answers
8k views

How many recombination events are there per generation in humans?

I'm looking for a reference that tells me how many recombenation events occur in humans from one generation to the next. Assuming that the human genome is a 3.3 GigaBases long DNA sequence, how many ...
2
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1answer
401 views

Does recombination increase the additive genetic variance for fitness?

On this article, first column, eighth line of the introduction: By bringing together favourable alleles from different chromosomes, sex and recombination increase the additive genetic variance for ...
7
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1answer
267 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
5
votes
1answer
785 views

Mitotic crossover happens in G1?

I was reading this article in wikipedia and came across this : It has been suggested that recombination takes place during G1, when the DNA is in its 2-strand phase, and replicated during DNA ...
4
votes
3answers
3k views

Why asexual reproduction?

When I took a course on genetics and evolution, I learned that recombination and sexual reproduction is advantageous compared to asexual reproduction. Sexual reproduction allows more combinations of ...
6
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1answer
2k views

Understanding recombination scoring in family pedigrees

I am having some problems understanding recombination, and I am not sure what element I am missing here. This figure is an example from my text book. The pedigree belongs to a family with an autosomal ...
0
votes
2answers
61 views

Using punnett squares to express sex/gene linkage and recombination frequency

I have been using punnett squares to visualize mating experiments. I am looking at a pairing which is known to have a crossover event occur. I know from empirically collected data the recombination ...