Questions tagged [renal-physiology]

The branch of physiology that deals with the kidneys, and their role in reabsorption, filtration, acid-base and electrolyte balance.

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11
votes
2answers
591 views

What can the timing of human urination tell about the human's physical condition and circadian rhythms?

I've noticed a peculiar phenomenon. A subject drinks 400 ml of water, then observes time until the urge to urinate is felt. The time is 15 minutes. The subject releases water. 14 minutes later another ...
11
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2answers
52k views

Glomerular Filtration Rate

In practice, when you have vasoconstriction of the glomerular capillaries and subsequently an increase in blood pressure, glomerular filtration rate increases. However, this seems counterintuitive to ...
8
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1answer
103 views

Which aspects of renal physiology are standing in the way of an artificial (mechanical) kidney?

Scientists have been able to create artificial organs with varying degrees of success. The mechanical heart (in its various forms, e.g. ventricular assist) is able to sustain life for some period of ...
7
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2answers
118 views

What is the benefit of near-emptying the bloodstream in the mammalian kidney?

In the normal function of the kidney, the bloodstream is near emptied of fluids as it moves through the glomerulus, in which glomerular filtrate is formed. As it proceeds through the Nephron, a ...
7
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1answer
6k views

Does THC excretion increase if urine volume increases?

In regards to the body metabolizing and excreting THC: if urination is increased as a result of drinking lots of fluids, does that mean that more THC is leaving the body? To rephrase the question, is ...
6
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3answers
8k views

Why do I want to urinate when I touch water?

I've noticed that whenever I come in contact with running water (especially when I do my dishes), I have a desire to urinate. A quick Google search (link,link) gave me few different hypotheses: Cold ...
5
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1answer
363 views

Can the kidneys utilize ketone bodies for energy?

Ketone bodies are water-soluble and should pose no problem to the kidneys because of solubility. If the kidneys are able to utilize ketone bodies for energy, then they must express the enzyme 3-...
4
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1answer
1k views

Is the amount of phosphoric acid added to colas enough to disrupt the function of the kidney over the long term?

Both Coca-Cola and Pepsi add phosphoric acid $H_3PO_4$ to their colas to give them a signature "bite". The kidneys use a phosphoric acid/dihydrogen phosphate/hydrogen phosphate homeostasis as one ...
3
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1answer
3k views

What are the highest and lowest possible pH, paCO2 and HCO3 in the blood of living human?

What are the highest and lowest possible values of pH, $paCO_2$, and $HCO_3$ in the (arterial or venous) blood of a living human being?
3
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1answer
2k views

Renorenal Reflex

According to this: The kidney contains afferent sensory nerve fibers that are located primarily in the renal pelvic wall where they sense stretch. I think the stretch is due to urine. If I am ...
2
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1answer
64 views

Ascending loop of Henle

When ions diffuse out passively or are actively transported out of the ascending loop of Henle, do those ions just hang around or do they go into the circulatory system and leave the kidney. I ask ...
1
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1answer
113 views

Does having to urinate imply that you are becoming dehydrated?

This question came up after I read another question that coffee does not dehydrate you, but instead acts as a mild diuretic. Does having to pee imply dehydration? Allow me to elaborate: When you ...
1
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1answer
104 views

Is the serum concentration of calcitriol different at different times in the day?

Given that calcitriol has a relatively short half-life in adults it would be possible that the serum concentration is at different times of the day different if it gets produced in different ...
1
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1answer
1k views

Why does renal artery stenosis lead to activation of Renin-Angiotensin system?

To my current understanding, stenosis or narrowing of the arteries would mean higher blood pressure, similar to atherosclerosis. So the Renin system should be suppressed to counter the high blood ...
1
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1answer
277 views

Can tubular secretion regarded as local hormone?

Tubular secretion is : The process in which ions and other waste products are transported into the distal tubules of the nephron. can it be regarded as local hormone??
1
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1answer
67 views

Can polystyrene sulfonate bind calcium or sodium in the gut? How?

Polystyrene sulfonate is used as a potassium binder to treat hyperkalemia in traumatic rhabdomyolysis, acute and chronic kidney disease. It is listed as an ion-exchange resin that can also remove ...
1
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2answers
3k views

How does the counter-current multiplier work in the nephrons?

Why is the counter-current multiplier called like that? What is flowing in the opposite direction to the glomerular filtrate for it to be called "counter-current"? Can you please explain the counter-...
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3answers
4k views

Why are lipid-soluble substances harder to excrete?

I understand why water-soluble substances can be excreted. However, why are they easier to excrete than lipid-soluble substances? Why can’t lipid-soluble substance be excreted just as easily in the ...
0
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1answer
717 views

What is titratable acid? Why is ammonium not titratable acid?

What exactly do we mean when we use term titratable acid in renal physiology? Why is ammonium not considered a titratable acid?
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0answers
9 views

How to generate kidney stones in animal models?

How can the major types of kidney stones (calcium oxalate, calcium phosphate, uric acid, struvite, or cystine) be induced in an animal model? I have noted in my research on this topic that calcium ...
0
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0answers
61 views

Microalbuminuria in inflammation of urinary tract

Albumin is excreted into urine (albuminuria) in nephrotic syndrome and in certain inflammatory conditions of urinary tract.$^1$ How is inflammation in urinary tract related to increase in albumin ...
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0answers
97 views

peritoneal dialysis Vs Hemodialysis?

Their are basically two types of dialysis: 1.peritoneal dialysis 2.hemodialysis, My Question is Why the peritoneal dialysis needs to be carried out on everyday BUT hemodialysis is carried out on only ...